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961
Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex.
Published 2009-08-01“…When the background DA was eliminated by depleting DA with reserpine and alpha-methyl-p-tyrosine, or by preparing corticolimbic co-cultures without the VTA slice, Up-states could be enhanced by low concentrations (0.1-1 microM) of DA that had no effect in the VTA containing cultures. Finally, in spite of the concentration-dependent effects on Up-states, exogenous DA at all but the lowest concentrations increased intracellular current-pulse evoked firing in all cultures underlining the complexity of DA's effects in an active network.…”
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962
In vitro and preclinical evaluation of the antifungal activity of 6-methoxy-1 H-indole-2-carboxylic acid produced by Bacillus toyonensis strain OQ071612 formulated as nanosponge hy...
Published 2025-04-01“…Abstract Background In a previous study, 6-methoxy-1 H-indole-2-carboxylic acid (MICA) was isolated from the culture broth of Bacillus toyonensis strain OQ071612 soil isolate in our laboratory, and it demonstrated promising antifungal activities. The current study was designed to create a nanosponge (NS)-hydrogel (HG)-containing MICA followed by in vitro and preclinical evaluation for potential clinical use in the topical treatment of mycotic infections. …”
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963
Malted Multi-millet based Probiotic Dairy Beverage: Nutritional, Sensory, Physicochemical and Microbiological Characterization
Published 2025-07-01“… In the current study conducted during November, 2023–April, 2024 , malted multimillet flours (MMF) viz., Finger millet, Foxtail millet and Little millet were used for preparation of probiotic lassi. …”
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964
Optimization of the defense forces personnel under mobilization conditions: The role of occupational selection as a personnel allocator
Published 2024-12-01“…The second problem is the age aspect in the ranges of 20-30, 30-40 and 40-60 years, for which it is necessary to develop and apply the criteria of occupational suitability for each of the currently relevant professions. A generalized definition of the psychological readiness state was formulated as a stable, multifaceted and hierarchically structured result of preparation for a certain activity, which contains a number of subsystems adequate to the requirements, content and conditions of the activity. …”
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965
New multifactor spatial prediction method based on Bayesian maximum entropy
Published 2013-11-01“…., organic matter and heavy metal content) are vital to soil quality evaluation and regional environment assessment. Currently, the spatial distribution of soil properties is usually predicted with classical geostatistics or environmental correlation. …”
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966
Illuminating Bilateral Breast Cancer: A Multicenter Experience and Clinical Observations
Published 2025-06-01“…In multivariate regression analysis, hormone receptor negativity was identified as an independent risk factor for decreased DFS among all BBC patients. Our study is noteworthy for shedding light on the clinical features of BBC in the context of current knowledge and for its multicenter design.…”
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967
Sargassum Enrichment in Mesoscale Eddies of the Great Atlantic Sargassum Belt
Published 2025-04-01“…Abstract Pelagic Sargassum has increased dramatically in the past decade, primarily in the annually recurrent Great Atlantic Sargassum Belt (GASB) that extends from the coast of West Africa to the Gulf of Mexico. …”
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968
Reducing the dietary starch:protein ratios in low-protein diets enhanced the growth performance of goslings from 1 to 28 days of age
Published 2025-01-01“…The current study aimed to explore the suitable starch: protein ratios under different dietary protein levels for goslings. …”
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969
Combined Oral Contraceptives for Polycystic Ovary Syndrome: <i>Pro</i> and <i>Contra</i> (Review)
Published 2024-07-01“…This study aimed to review current data on the use of COCs in PCOS, focusing on the rationality of prescribing, the main risks of using COCs, and the measures to minimise these risks.DISCUSSION. …”
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970
The Comparison of Effects of Supplementation of Zeolite and Yucca Schidigera Powder to Diet on Liver Enzymes (AST, ALT, GGT) in Sheep
Published 2020-09-01“…The concern of utilizing native coraps as forage supplements instead of antibiotics has increased in order to manipulate rumen fermentation.The purpose of current work was to determine effects of co-addition zeolites of and Yucca schidigera (YS) plant containing high level of saponin to sheep feed on plasma Aspartat aminotransferaz (AST), ALT (Alanin aminotransferaz) and Gama glutamil transferaz (GGT) levels. …”
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971
Soil remediation at coastal plains with the help of DC Resistivity Method
Published 2025-04-01“…For each type of metal, electrode pairs were placed in the soil that was filled in a plastic container. Current variation was monitored while 1 VDC/cm was applied to electrodes. …”
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972
Commonly prescribed medications and risk of pneumonia and all-cause mortality in people with idiopathic pulmonary fibrosis: a UK population-based cohort study
Published 2025-01-01“…We also observed a small increased risk for all-cause mortality in the “regular ICS user” group compared with the “non-user” control group (HRadj = 1.19, 1.06–1.33). …”
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973
Paroxysmal Sympathetic Hyperactivity Syndrome (Review)
Published 2022-08-01“…We conclude the review with a discussion of current methods of the syndrome prevention.Conclusion. …”
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974
Essential oils – a review of the regulatory framework in the European Union
Published 2025-04-01“…The current trend in consumers’ preferences for healthy lifestyles resulted in an increased demand for natural products. …”
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975
Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4
Published 2025-12-01“…Furthermore, MUC4 overexpression in the context of HIF-1α knockout was positively correlated with increased ECM protein expression and TIF. …”
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976
Standards of Specialized Diabetes Care / Edited by Dedov I.I., Shestakova M.V., Mayorov A.Yu. 11th Edition
Published 2024-01-01“…These evidence-based guidelines were designed to standardize and facilitate diabetes care in all regions of the Russian Federation.The Standards are updated on the regular basis to incorporate new data and relevant recommendations from national and international clinical societies, including World Health Organization Guidelines (WHO), International Diabetes Federation (IDF), European Association for the Study of Diabetes (EASD), American Diabetes Association (ADA), American Association of Clinical Endocrinologists (AACE), International Society for Pediatric and Adolescent Diabetes (ISPAD) and Russian Association of Endocrinologists (RAE). Current edition of the “Standards” also integrates results of completed randomized clinical trials, as well as findings from the national studies of diabetes mellitus (DM), conducted in close partnership with a number of Russian hospitals.Latest data indicates that prevalence of DM in the world increased during the last decade more than two-fold, reaching some 537 million patients by the end of 2021. …”
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977
Exploring Growth of Gracilaria sp. using the Raft Culture Method
Published 2024-12-01“…The results indicated that pH, conductivity, TDS, and turbidity were within the normal range, whereas temperature, salinity, DO, and water current were above the average. Gracilaria's weight increased consistently every 15 days, reaching a peak of 22.99 g on the 105th day. …”
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978
A numerical investigation of heat and mass transfer in the bioconvective Oldroyd B nanofluid flow through the porous stretching Riga surface with gyrotactic microorganism
Published 2025-08-01“…A time-varying Lorentz force induces vertical current flow in the fluid, an effect modeled using a Riga plate under an applied electromagnetic field. …”
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979
MaxEnt-Based Distribution Modeling of the Invasive Species <i>Phragmites australis</i> Under Climate Change Conditions in Iraq
Published 2025-03-01“…There is an insufficient understanding of both the current distribution and possible future trends under climate change scenarios. …”
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980
The implementation of Safety Management Systems in healthcare: a systematic review and international comparison
Published 2025-03-01“…Safety management systems need to be context-specific to be effective. Evidence on the use of safety management systems in health care is therefore needed to inform policy decisions. …”
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