Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy by Chao Lv, Chao Lv, Chao Lv, Chao Lv, Chao Lv, Lei Zhao, Jiani Hou, Hongyin Sun, Hongyin Sun, Hongyin Sun, Zhongsha Li, Zhongsha Li, Zhongsha Li, Zhongsha Li, Yuesong Wu, Yuesong Wu, Yuesong Wu, Yuesong Wu, Peizheng Shi, Yaping Xiao, Yunjin Xie, Yunjin Xie, Yunjin Xie, Yunjin Xie, Wei Su, Wei Su, Wei Su, Wei Su, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin, Mingzhu Yin

“…Histological analysis demonstrated that TFA alleviated hepatic steatosis and fibrosis, with decreased levels of inflammatory cytokines and increased antioxidant markers. …”
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SOUTH AFRICAN USERS’ FUNCTION AND EXPERIENCE WITH A MAGNETORHEOLOGICAL MICROPROCESSOR KNEE: A MIXED METHODS STUDY by Surona Visagie, Benje Theron

“…CONCLUSION: This study provides context specific scientific evidence that may support funding decisions for MPKs in South Africa. …”
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Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning by Bronagh Walsh, Carole Fogg, Tracey England, Sally Brailsford, Paul Roderick, Scott Harris, Simon Fraser, Andrew Clegg, Simon de Lusignan, Shihua Zhu, Francesca Lambert, Abigail Barkham, Harnish Patel, Vivienne Windle

“…Prescriptions increased with increasing age in both Fit and Mild frailty categories but decreased in moderate and severe categories. …”
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Anticipating how spatial fishing restrictions in EU waters perform to protect marine species, habitats, and dependent fisheries by François Bastardie, Amaia Astarloa, Logan Binch, Isabella Bitetto, Dimitrios Damalas, Jochen Depestele, Pierre-Yves Hernvann, Sigrid Lehuta, Jonas Letschert, Irida Maina, Stéphanie Mahévas, Georgia Papantoniou, Miriam Püts, Giovanni Romagnoni, Giovanni Romagnoni, Giovanni Romagnoni, Giovanni Romagnoni, Maria Teresa Spedicato, Klaas Sys, Irini Tsikopoulou, Gert Van Hoey, Walter Zupa, Anna Rindorf

“…As the proportion of closed regions increases, potential effects on marine ecosystems can even be damaging in the short term to some sensitive species (such as the endangered, threatened and protected species ETP) and vulnerable habitats (with currently high relative benthic status RBS). …”
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Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components by Marion Henderson, Anja Wittkowski, Katie Buston, Karen Crawford, Alice MacLachlan, Alex McConnachie, Emma McIntosh, Claudia-Martina Messow, Catherine Nixon, Rosaleen O’Brien, Shona Shinwell, Daniel Wight, Yiqiao Xin, Rachel Calam, Ruth Dundas, James Law, Helen Minnis, Lucy Thompson, Philip Wilson

“…Mellow Bumps in comparison, comprises of seven weekly antenatal sessions and one postnatal session. It aims to decrease maternal stress, increase understanding of neonates’ capacity for social interaction, and emphasise the importance of early interaction for brain development and attachment. …”
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Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

“…In the United Kingdom, the uptake of antiretroviral therapy is generally high, but a delay in starting antiretroviral therapy and non-adherence compromise the health and well-being of people living with human immunodeficiency virus, increase the risk of transmission of human immunodeficiency virus and increase National Health Service costs. …”
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Protecting the Autonomy of Patients with Severe Mental Illness Through Psychiatric Advance Directive Peer-Facilitation by Nicholas Karasik

“…Guiding Distributive Justice: Capability Theory Capability theory is an account of justice opportunity that places a fundamental moral significance on individuals' ability to reach proper functioning and well-being.[52] Whether or not an individual can make use of a particular set of resources and convert them into a state of functioning depends on personal, sociopolitical, and environmental conditions ("conversion factors").[53] In this sense, liberty is not the absence of restraint from others or institutions but the freedom achieved through capability-enhancing relationships.[54] Within the context of bioethics, capability theory shifts focus toward creating circumstances by which individuals can direct their lives as they choose.[55] Acting in accordance with the principle of beneficence, peer-support specialists could enhance the capability of patients to be self-determined and autonomous, which would promote patient well-being and empowerment.[56] Those living with SMI, such as schizophrenia and bipolar disorder, are among the most disadvantaged in society, experiencing social and economic hardship related to their illness.[57] These individuals are often feared and rejected by others, which increases depression, lowers self-esteem, and engenders feelings of social isolation.[58] Compounding their challenges, especially for those facing structural inequalities, is insufficient access to appropriate mental health services supporting recovery.[59] Capability theory provides a sound justification for the resource distribution necessary to create and sustain a thriving network of peer-support specialists, to which those with SMI currently do not have access. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…Recommendation for Simultaneous Allograft Listing Ethical research design calls for assessments of which vulnerabilities and in which contexts researchers and IRBs ought to offer additional safeguards. …”
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