Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

“…By elucidating the precise underlying mechanisms, these drugs could emerge as promising therapeutic options, particularly in the context of combination therapy for ALL.…”
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Failure behavior of tantalum electrolytic capacitors under extreme dynamic impact: Mechanical–electrical model and microscale characterization by Xiangyu Han, Da Yu, Cheng Chen, Keren Dai

“…It is found that the leakage current of tantalum capacitors increases sharply under extreme impact, causing functional failure. …”
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Investigating Awareness of Pesticide Exposure as a Risk Factor for Parkinson’s Disease and Uptake of Exposure-Mitigating Behaviour in Farming Communities in Ireland by Lucy M. Collins, Éilis J. O’Reilly, Joan Omosefe Osayande, Fionnuala Wilson, Jolie Morisho, Rebekah Bevans, Rachel Roberts, Bereniece Riedewald, Louise M. Collins, Gerard W. O’Keeffe, Aideen M. Sullivan

“…An online survey was completed by a sample of the farming community (<i>n</i> = 707) attending agricultural fairs, and included demographics, lifetime/current residence/work on farms, pesticide contact, PPE use, PD diagnosis, and awareness of pesticide–PD association. …”
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High prevalence of the hotspot complement factor I p.Ile357Met pathogenic variant in Tunisian atypical hemolytic uremic syndrome patients: report of three new cases and review of t... by Asma Tajouri, Asma Tajouri, Asma Tajouri, Imen Ayadi, Imen Ayadi, Rimeh BenBrahim, Rimeh BenBrahim, Ikram Mami, Abir Boussetta, Hend Jlajla, Hend Jlajla, Yousr Zerzeri, Haifa Arbi Sassi, Jamila Ben Sassi, Hela Sahli, Lilia Laadhar, Lilia Laadhar, Tahar Gargah, Mohamed Karim Zouaghi, Maryam Kallel Sellami, Maryam Kallel Sellami

“…The recurrence of this variant in the Tunisian cohort led us to suggest that it could be characteristic of the Tunisian population.MethodsIn this context, we conducted the current study which included 8 adults and three children with suspected aHUS and decreased factor I levels, as well as one relative. …”
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DEVELOPMENT OF AUTOMATED EXCITATION AUXILIARY CUTTING SIMILAR EXPERIMENT PROTOTYPE AND ITS MECHANICAL EXPERIMENT by LU JinNan, YUE JianGuang, XIE Miao, WANG PengFei

“…The experimental results show that during the same time period, when there is active excitation, the initial time for increasing contact force is 0.07 s earlier than when there is no excitation, longer duration, contact force is reduced by 0.12 kN compared with no excitation, after excitation, the average cutting current decreased by 1.12 A.Through the test bench based on Similarity theory, the active excitation vibration experiment and test can be carried out on the cutting arm of the road-header under limited laboratory conditions. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…The enrichment analysis highlighted the fundamental pathways where the NOTCH1- and SF3B1-associated ceRNA network exerts its influence in the context of CLL. Conclusions This study implies the efficacy of combined therapy by CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs and PTX as a novel therapeutic strategy for CLL, even though further studies are required to warrant the findings. …”
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Investigating the Existence of a Cathode Electrolyte Interphase on Graphite in Dual‐Ion Batteries with LiPF6‐Based Aprotic Electrolytes and Unraveling the Origin of Capacity Fade... by Lukas Haneke, Felix Pfeiffer, Katharina Rudolf, Pranti Sutar, Masoud Baghernejad, Martin Winter, Tobias Placke, Johannes Kasnatscheew

“…Affirmed by Raman spectroscopy and scanning electron microscopy, the active material remains structurally stable, suggesting capacity fading to be dominated by resistance rise at the PE, likely due to an electronic contact resistance from active material grain boundaries and/or from the interface between electrode particles and the current collector in course of high volume changes; as systematically derived by impedance spectroscopy.…”
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‘Mental heAlth and well-being in rUgby pLayers’ (MAUL) study: an online survey of diverse cohorts of rugby union players internationally by Jon Patricios, Paul Kelly, Simon Kemp, Debbie Palmer, Karim Khan, Caithriona Yeomans, Kathryn Dane, Steffan Griffin, Samantha Fawkner, Heather Lewis, Kearnan Myall, Rebecca Syed Sheriff, Kaitlin Simpson

“…Evidence suggests that physical activity and sports benefit mental health and well-being, and rugby provides health-enhancing moderate-to-vigorous physical activity.Objective This cross-sectional study used an online approach and engaged national rugby governing bodies to understand adult rugby players’ mental health and well-being and increase the diversity of the current evidence base.Results 500 rugby players completed an online survey. 44% of participants identified as female, and 55% as male. …”
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Job Satisfaction Analysis of Nurses, who Work in Neurology and Neurosurgery Units by Anna Rymkiewicz

“…Satisfaction, facing problems and motivation are currently strategic points to be analysed in terms of nurses’ work. …”
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Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

“…Modification of the CCL2 secretion seemed to be context dependent in the human explants: where EVs treatment stimulated CCL2 secretion but in the presence of IL‐1β this effect was counteracted. …”
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Value foundations of experiencing stress and adaptation of students: Cross-cultural study by E. I. Koltunov, V. G. Gryazeva-Dobshinskaya, Ya. A. Dmitrieva, N. V. Markina, J. Zhi, E. S. Naboichenko

“…Present work is dedicated to an urgent problem that has emerged as a result of a global trend – an increase in the number of young people moving to other countries in search for a higher education, which often leads to stress during the process of cultural adaptation.In the current research, the authors conducted a comparative analysis of the normative and individual values of students from China and Russia, studying at the Russian university. …”
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Computerized and distance learning systems (the case of medical diagnostics) by B. A. Kobrinsky

“…The purpose of this paper is to analyze the current state and the possibility of developing computer systems of various types in education (the case of medicine). …”
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Monkeypox: Prevention Strategies and Challenges: Updated Review by Abate Wondesen Tsige, Siraye Genzeb Ayele

“…The mpox can spread from person to person through direct contact with infectious skin or other lesions, such as those on the mouth or genitalia. …”
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Enhanced Electrochemical Performance of Dual-Ion Batteries with T-Nb₂O₅/Nitrogen-Doped Three-Dimensional Porous Carbon Composites by Chen Qi, Duo Ying, Cheng Ma, Wenming Qiao, Jitong Wang, Licheng Ling

“…The obtained T-Nb₂O₅/RMF composites have a well-developed pore structure and a high specific surface area of 1568.5 m² g⁻¹, which could effectively increase the contact area between the material and electrolyte, improving the electrode reaction and lithium-ion transfer diffusion. …”
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ORGANIZING SELF-EDUCATION ACTIVITIES FOR MEDICAL COLLEGE STUDENTS IN THE CONTEXT OF BLENDED LEARNING by Pysmenna Oleksandra

“…The article aims to review current trends in the organization of self-education activities for medical college students, models of blended learning, and its main components that ensure the self-education of future nursing specialists. …”
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Dynamic Analysis of Pantograph-Catenary System considering Ice Coating by Yongming Yao, Ning Zhou, Guiming Mei, Weihua Zhang

“…Specifically, as the speed of trains increases, the effect of ice thickness on the current collection quality of the PAC system is becoming increasingly apparent.…”
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Performance and Reliability Assessment of Schottky Complementary Multi-FinFET Inverter for Advanced Scaling Nodes by Shalini Virumandi, Prashanth Kumar

“…The results indicate that the 5 nm node exhibit superior performance compared to other nodes, with improved electrostatic control, higher drive current (0.00212 for n-FinFET, -<inline-formula> <tex-math notation="LaTeX">$1.16\times 10 ^{-4}$ </tex-math></inline-formula> for p-FinFET), and lower leakage current, making them suitable for low-power applications. …”
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A Deep Learning-Based Diagnostic Framework for Shaft Earthing Brush Faults in Large Turbine Generators by Katudi Oupa Mailula, Akshay Kumar Saha

“…The framework was evaluated using data from a fleet of large-scale generators under various brush fault scenarios (e.g., increased brush contact resistance, loss of brush contact, worn out brushes, and brush contamination). …”
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Cutaneous Adverse Effects From Diabetes Devices in Pediatric Patients With Type 1 Diabetes Mellitus: Systematic Review by Alicia Podwojniak, Joseph Flemming, Isabella J Tan, Hira Ghani, Zachary Neubauer, Anne Jones

“…ConclusionsThe dermatologic complications of CGM and CSII pose a potential risk to long-term glycemic control in T1D, especially in young patients where skin lesions can lead to discontinuation. Increased manufacturer transparency is critical and further studies are needed to expand upon the current preventative measures such as device site rotation and steroid creams, which lack consistent effectiveness.…”
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Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study by Meera M. Dhodapkar, MD, MHS, Scott J. Halperin, MD, MHS, Wesley Day, BA, Comron Saifi, MD, Daniel R. Rubio, MD, Fotios Koumpouras, MD, Jonathan N. Grauer, MD, Arya Varthi, MD

“…ABSTRACT: Background context: Posterior lumbar fusion (PLF) is a common procedure, for which patients with systemic conditions may be considered. …”
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