Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
Get full text

Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…CE-MS peptidome analysis identified 191 significantly altered peptides in severely injured patients. A consistent increase in the abundance of peptides from A1AT, AHSG, and HBA1 was observed, while peptides derived from PIGR and UROM were consistently decreased. …”
Get full text

Philosophy of School Multilingualism in the Era of Political Multiculturalism. French Experience. Case of France by N. V. Litvak

“…A philosophical understanding of the data of sociology, cultural anthropology, social psychology (on the example of France) on the problem of school education as one of the mechanisms for the transmission of culture in the context of multilingualism is proposed.Results and discussion. …”
Get full text

Drivers of Food Service Need and Use among Non-Hispanic Black and Hispanic Men with Chronic Conditions in the United States by Jeong-Hui Park, Tyler Prochnow, Ledric Sherman, Caroline D. Bergeron, Ashley Merianos, Babatunde Olubajo, Sanjeela Gandhari, Matthew L. Smith

“…Food insecurity is predominant and differs across certain races and ethnicities, which highlights the importance of community-based food service access and utilization. In this context, the current study examined factors associated with community-based food service needs and utilization among middle-aged and older non-Hispanic Black and Hispanic men with chronic conditions. …”
Get full text

Analyzing outcomes for peripheral versus central administration of vasopressors: A narrative review by Jack Dryden, Jose Navas-Blanco

“…There is an emerging body of evidence to suggest that the peripheral administration of vasopressors is safe and effective in many clinical contexts and often superior to central administration. …”
Get full text

The influence of entrepreneurial role model on entrepreneurial intention: a cross-level investigation by Mu Xuan, Liu Yankai

“…Social implications – At the same time, role models should be presented differently in diverse cultural contexts. For example, in countries with a strong collectivist orientation, the media should include collectivist messages when promoting entrepreneurial role models, such as his cooperation with the government, family and friends, which is in line with collectivist values, so that potential entrepreneurs in a collectivist context may perceive more similarity to role models and thus increase their entrepreneurial intentions (Morris et al., 1994); On the contrary, in countries with low collectivist tendencies, the media can appropriately carry an element of individualism when promoting entrepreneurial role models, for example, by telling how entrepreneurs succeed on their own strength and superior abilities, which is in accordance with the values of individualism. …”
Get full text

Insomnia, Cognitive Impairment, or a Combination of Both, Alter Lipid Metabolism Due to Changes in Acylcarnitine Concentration in Older Persons by Selma Karime Castillo-Vazquez, Berenice Palacios-González, Marcela Vela-Amieva, Isabel Ibarra-González, Ricardo Morales, Paola García-delaTorre, Sergio Sánchez-García, Carmen García-Peña, Ricardo Reyes-Chilpa, Raúl Hernán Medina-Campos, Jessica Hernández-Pineda, Juan Carlos Gomez-Verjan, Nadia Alejandra Rivero-Segura

“…Results: Our results show that insomnia increases the concentration of acylcarnitines (C10, C8, C14, C12:1, C18:1 and C18) as compared to CI group, while older persons with CI show a decrease the concentration of the acylcarnitines C16, C10 and C8. …”
Get full text

Winter wheat yield responses to growing degree days: Long-term trends and adaptability in major producing areas of China by Ziyang Liu, Davide Cammarano, Xiaojun Liu, Yongchao Tian, Yan Zhu, Weixing Cao, Qiang Cao

“…The number of days in the growth period during the sowing-to-jointing stage and jointing-to-flowering stage decreased significantly, the number of days during the flowering-to-maturity stage increased significantly. …”
Get full text

AI as a creative partner: a PRISMA review of AI’s role in supporting creativity in education by Alex Urmeneta, Margarida Romero, Margarida Romero

“…Creativity is considered an important competency for personal and professional development in the current society. With the integration of artificial intelligence (AI) in education, there is increasing interest in understanding how AI can support the creative process and how its usage in various contexts might affect user agency. …”
Get full text

A Comparative Approach of Cultural Intelligence Profile of Management and Non-Management Romanian Students by Laura BRANCU, Valentin MUNTEANU, Ionut GOLET

“…Cultural intelligence (CQ) is defined as the as individuals’ ability to act efficiently in different cultural contexts. Due to a significant growth of Internet-based communication, enabling virtual work teams, geographically and culturally dispersed (Stanko & Gibson , 2009), and to increased globalization over the past 20 years, the number of people who currently get in touch with other cultures has grown significantly (Eisenberg et al., 2013). …”
Get full text

Valorization of 3D/4D models of disappeared or ruined heritage sites in 3D modeling environments by M. Koehl, J.-E. Heitz, E. Sommer, M. Fuchs

“…These models allow for the restoration of shapes and dimensions, and their placement within a historical context. To help users better project themselves, it is also interesting to place them in current urban contexts. …”
Get full text

Healthcare workers’ perceptions of patient safety culture in emergency departments: a scoping review by Min Ji Kim, Ming Wei Jeffrey Woo

“…Objective This review aimed to map the concept of patient safety culture in emergency departments (EDs), describe the availability of evidence related to patient safety culture as assessed by healthcare workers, identify the key focus areas of existing studies and pinpoint gaps in the current literature.Design A scoping review followed a comprehensive methodological process that included five steps based on the framework developed by Arksey and O’Malley and updated by Peters et al.Eligibility criteria Studies encompassing original research and all pertinent published and grey literature within the last 15 years (2010–2024) that aligned with the population (healthcare workers), concept (patient safety culture) and context (emergency department) framework for this study were included.Data sources PubMed, CINAHL (EBSCOhost), WOS, Embase, MEDLINE (Ovid), and KISS databases were searched for original studies published between 2010 and 2024 that aligned with the topic of this study.Data extraction and synthesis Two researchers independently extracted data from 28 eligible articles using a predetermined data extraction tool. …”
Get full text

Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
Get full text

The examination of family value hierarchies in Russian and Chinese cultures by O. E. Iatsevich, V. V. Iudashkina, L. N. Shabatura, N. A. Tkacheva, A. F. Zakirova

“…Introduction. In the context of globalisation and the intensification of international contacts, there is an increasing need to understand the intercultural differences and similarities between Russian and Chinese youth, particularly in significant areas such as family values. …”
Get full text

USE OF AGRICULTURAL POTENTIAL FOR ECONOMIC RECOVERY/GROWTH by Ana-Maria IFRIM, Marius-Mihai MICU, Oana-Raluca RUSU, Catalin Ionut SILVESTRU, Cristina Vasilica ICOCIU

“…In the current context, after a pandemic that has left traces in all socio-economic fields and during major geo-political problems, Basic research is needed in order to identify directions for rapid and sustainable socio-economic recovery. …”
Get full text

The Immune Environment in Colorectal Adenoma: A Systematic Review by Ugne Silinskaite, Jurate Valciukiene, Matas Jakubauskas, Tomas Poskus

“…<b>Methods:</b> In this systematic review, we aim to provide a thorough analysis of the current research examining the immune infiltration patterns in sporadic colorectal adenoma tissues in the context of immune cell-based, cytokine-based, and other immunological factor-related changes along the conventional adenoma–carcinoma sequence. …”
Get full text

TRENDS REGARDING DEVELOPMENT THE SUSTAINABLE WINE TOURISM IN THE REPUBLIC OF MOLDOVA by Viorica GUȚAN, Constanta Laura ZUGRAVU, Maria Magdalena TUREK RAHOVEANU, Gheorghe Adrian ZUGRAVU

“…In this context, the purpose of the paper is to identify and analyze the current trends and developments in the wine tourism sector in Moldova, focusing on sustainable practices. …”
Get full text

Importance of Cheese Whey Processing: Supplements for Sports Activities – a Review by Patricia Fassina, Gabriela Quadros Nunes, Fernanda Scherer Adami, Márcia Inês Goettert, Claucia Fernanda Volken de Souza

“…Whey protein (WP) is a highly nutritious, commercially available alternative food source that is used primarily as a food supplement by athletes and physically active individuals to provide them with essential amino acids and bioactive peptides, and additional benefits have been attributed to WP consumption. In this context, the objective of this review was to explore current evidence regarding the consumption of different WP supplements in sports nutrition to elucidate their efficiency in affecting muscle hypertrophy, physical performance, response to muscle injury, weight loss, and body composition changes. …”
Get full text

Characterizing dengue transmission in rural areas: A systematic review. by Olivia Man, Alicia Kraay, Ruth Thomas, James Trostle, Gwenyth O Lee, Charlotte Robbins, Amy C Morrison, Josefina Coloma, Joseph N S Eisenberg

“…In some rural areas, the force of infection appears to be increasing over time, as measured by increasing seroprevalence in children and thus likely decreasing age of first infection, suggesting that rural dengue transmission may be a relatively recent phenomenon. …”
Get full text

Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
Get full text