Biochemical detection of pediatric eosinophilic esophagitis using high wavenumber Raman endoscopy and stimulated Raman microscopy by Ezekiel J. Haugen, Andrea K. Locke, Lily H. Dao, Alec B. Walter, Pratheepa K. Rasiah, Justin S. Baba, Matthew A. Buendia, Hernán Correa, Girish Hiremath, Anita Mahadevan-Jansen

“…The high wavenumber Raman spectrum contains quantitative information about the biochemical and water content in tissue. …”
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Impact of residual risk messaging to reduce false reassurance following test-negative results from asymptomatic coronavirus (SARS-CoV-2) testing: an online experimental study of a... by Leah Ffion Jones, Richard Amlot, Dale Weston, Holly Carter, Theresa Marteau, Natalie Gold, Eleonore Batteux, Stefanie Bonfield

“…Each message contained either no additional information or information about the need to continue following guidelines and protective behaviours.Outcome measures (1) Proportion understanding residual risk of infectiousness and (2) likelihood of engaging in protective behaviours (scales 1–7).Results The control message decreased understanding relative to the current NHS T&T message: 54% versus 71% (Adjusted Odds Ratio (AOR)=0.56 95% CI 0.34 to 0.95, p=0.030). …”
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Phytochemical Investigations and Pharmacological Potential of Organic Extracts of Calotropis gigantea L. Leaves by Adil Jamal, Amina Arif, Shumaila Kiran, Muhammad Naveed Shahid, Md. Belal Hossain

“…The results of our investigation indicate that the organic fractions exhibited reduced hemolytic activity, suggesting an enhanced medicinal potential and decreased toxicity of C. gigantea extracts. Based on the current results, it can be inferred that extracts derived from C. gigantea have diverse potential and urge further investigation as a possible reservoir of metabolites, antioxidants, and antibacterial compounds. …”
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Polarization of T-helper 2 to 1 phenotype has arisen in rat asthmatic pulmonary tissue after intra-tracheal administration of bone marrow-derived c-Kit+ cells by Fatemeh Mir-ershadi, Mahdi Ahmadi, Reza Rahbarghazi, Hossein Heiran, Aref Delkhosh, Majid Khaksar, Rana Keyhanmanesh

“…Conclusions: The results of the current experiment highlighted the therapeutic capacity of c-Kit+cells in the alleviation of asthmatic changes at the cellular level.…”
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A Rotated Object Detection Model With Feature Redundancy Optimization for Coronary Athero-Sclerotic Plaque Detection by Xue Hao, Haza Nuzly Abdull Hamed, Qichen Su, Xin Dai, Linqiang Deng

“…Current methods for addressing redundant features rely mostly on simple feature selection or reduction methods, overlooking the significance of redundant features in model training. …”
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Perspectives for Surrogate Safety Studies in East-European Countries by Rasa Ušpalytė-Vitkūnienė, Aliaksei Laureshyn

“…The method is put in the context of the East-European countries to see how it contribute to the on-going road safety work and a better understanding of accidents risk factors necessary for producing effective safety countermeasures.…”
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Oral pathology induced by excess or deficiency of glucocorticoids in adults by Rucsandra Elena Dănciulescu Miulescu, Loreta Guja, Bogdan Socea, Anca Dumitriu, Stana Paunica, Emil Ștefănescu

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Lithologically constrained velocity–density relationships and vertical stress gradients in the North Alpine Foreland Basin, SE Germany by P. Obermeier, F. Duschl, M. C. Drews

“…In SE Germany, the North Alpine Foreland Basin (NAFB) is a well-studied sedimentary basin, which was extensively explored for oil and gas in the last century and which is currently explored and exploited for deep geothermal energy. …”
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Changes in tree-ring wood density of European beech (Fagus sylvatica L.), silver fir (Abies alba Mill.), and Norway spruce (Picea abies (L.) H. Karst.) in European mountain forests... by Chiara Torresan, Torben Hilmers, Admir Avdagić, Edmondo Di Giuseppe, Matija Klopčič, Mathieu Lévesque, Florian Motte, Enno Uhl, Tzvetan Zlatanov, Hans Pretzsch

“…Abstract Key message We found a significant increase in the latewood density of European beech, and a decrease in the latewood and mean wood density of silver fir and Norway spruce in European mountain forests over the period 1901–2016. …”
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Understanding the effectiveness and underlying mechanisms of lifestyle modification interventions in adults with learning disabilities: a mixed-methods systematic review by Dikshyanta Rana, Sophie Westrop, Nishant Jaiswal, Evi Germeni, Arlene McGarty, Louisa Ells, Phillippa Lally, Michael McEwan, Craig Melville, Leanne Harris, Olivia Wu

“…Following this, the specific interacting contexts and underlying mechanisms were appraised, and the synthesis focused on developing context–mechanism–outcome configurations (CMOCs), which formed the basis of the emerging programme theory. …”
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The Comparison of Effects of Supplementation of Zeolite and Yucca Schidigera Powder to Diet on Liver Enzymes (AST, ALT, GGT) in Sheep by Oğuz Kale, İbrahim Durmuş

“…The concern of utilizing native coraps as forage supplements instead of antibiotics has increased in order to manipulate rumen fermentation.The purpose of current work was to determine effects of co-addition zeolites of and Yucca schidigera (YS) plant containing high level of saponin to sheep feed on plasma Aspartat aminotransferaz (AST), ALT (Alanin aminotransferaz) and Gama glutamil transferaz (GGT) levels. …”
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Trends in prevalence and patterns of use of a heated tobacco product (IQOS™) in Japan: A three-year repeated cross-sectional study [version 2; peer review: 1 approved, 2 approved w... by Steve Roulet, Karina Fischer, Pierpaolo Magnani, Bertram Zwisele, Nathalie Camille, Suzana AlMoosawi, Marius Sieverding, Martha Bajec, Nelly Mainy

“…Background: Numerous smoke-free tobacco or nicotine-containing product (TNP) alternatives have been introduced to support individual- and population-level harm reduction relative to continued cigarette smoking. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Context : Lymphangiomas are developmental anomalies presenting mainly in the first two years of life. …”
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Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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Meta-analysis on the effects of chemical stressors on freshwater ecosystem functions by Alexander Feckler, Ralf Schulz, Ralf B. Schäfer

“…These include expanding the range of chemical stressors investigated, accounting for the context-dependency of chemical effects on ecosystem functions, and complementing laboratory studies with semi-field and field experiments to verify and validate laboratory-derived findings under more realistic environmental conditions.…”
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Quality failures in Energy- saving renovation projects in Northern China by Yuting Qi

“…The novelty of this study lies in the fact that it explored and analysed the causes systematically from two main aspects in the context of China: the importance of a cause and the level of effort required to address a cause. …”
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Improving Growth Performance, Biochemical Parameters and Reducing Mortality due to Ascites in Broilers by Propranolol Inclusion by Shahriar Saidian, Somaya Farahmand, Mokhtar Fathi, Salar Saifi

“…To induce ascites, water containing 7 g per liter of salt was provided to the chickens from day 15 of age. …”
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Chemical characterization and cytotoxic effect of three edible fungi (Morchella) against breast cancer cells: A therapeutic approach

“…This present study aimed to explore the cytotoxic activity of Morchella extracts in the context of the MCF-7 cell line (breast cancer) and ultra-performance liquid chromatography mass spectroscopy (UPLC-MS) analysis. …”
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Lifelong Learning and Employability in the Danube Region Countries: Influences and Correlations by Constanţa-Nicoleta Bodea, Maria-Iuliana Dascălu, Gordana Velikic, Stelian Stancu

“…The conclusions of the current study are particularly important in the Romanian context, as the employment rate of recent graduates is in a decreasing trend, but also for all the Danube Region ex-communist countries, which have to boost their employment rates as well, to assure their economical growth. …”
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GBD: incidence rates and prevalence of anxiety disorders, depression and schizophrenia in countries with different SDI levels, 1990–2021 by Jueqi Wang, Xue Guan, Ning Tao

“…Data were categorized into 5-year age groups and 95% uncertainty intervals (UI) were calculated to account for data variability.ResultsIn countries with different SDI levels, the age-standardized average annual percentage change (AAPC) in the incidence of anxiety were all shown to be increasing, and there were large gender differences between the different SDI levels, with a maximum of 0.97 (0.76–1.18) for females in countries with a high SDI level, Age-standardized more rates per 100,000 people in high SDI countries, from 658.87 in 1990 to 841.56 in 2021, and the largest gender differences in countries with a low to moderate SDI level, with AAPCs for males and females of 0.04 (0.04–0.05), 0.86 (0.63–1.09); for depression, only the countries with medium-high SDI levels were statistically significant compared to the countries with medium-low SDI levels, with AAPCs of 0.05 (0.04–0.07), 0.04 (0.04–0.05); for schizophrenia in addition to the AAPCs of the countries with medium-high SDI levels showed an increase of 0.16 (0.13–0.18); the rest decreased.ConclusionThis study highlights the current status of global incidence and prevalence of mental disorders and examines the complex interactions between the period of onset and cohort of onset of mental disorders using APC modeling, with differences in gender differences in mental disorders in countries with different SDIs, and significant differences in countries with low to medium SDI levels, requiring further exploration of the mechanisms by which socio-economic development influences gender-specific mental health. …”
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