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Showing 361 - 380 results of 479 for search '(( current decrease in (contexts OR context) ) OR ( current decreased in (contexts OR context) ))', query time: 0.18s Refine Results
  1. 361

    Complementary Strategy of Maternal Immunization with RSVpreF Vaccine and Monoclonal Antibodies for the Prevention of Respiratory Syncytial Virus Among Italian Infants: A Cost-Effec... by Barbara Polistena, Fabio Midulla, Giovanni Sotgiu, Daniela d’Angela, Roberto Di Virgilio, Federico Spandonaro

    Published 2025-07-01
    “…Methods Using a model (with a cohort framework and a Markov-type process) specifically adapted to the Italian context, the study provided cost-effectiveness and cost-utility assessment of prevention strategies adding the maternal vaccination to the existing immunization opportunities with palivizumab or nirsevimab administered to high risk and unprotected infants. …”
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    Article
  2. 362

    Increasing day three parasitaemia is observed after treatment of patients with artemether-lumefantrine and single dose of primaquine for uncomplicated Plasmodium falciparum malaria... by Bontu Abate, Bokretsion Gidey Brhane, Tsegahun Manyazewal, Hussien Mohammed, Yonas Wuletaw, Moges Kassa, Mesay Hailu, Getachew Tollera, Geremew Tasew, Ashenafi Assefa, Eyasu Makonnen

    Published 2025-03-01
    “…These findings support the ongoing use of AL with a single dose of PQ as the primary treatment option for uncomplicated P. falciparum infections in the study area. In the context of the emergence and spread of partial artemisinin-based combination therapy(ACT) resistance in Africa, regular monitoring of the efficacy of current artemisinin-based combinations is recommended for the early detection of emerging drug resistance in the study setting and beyond.…”
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  3. 363
  4. 364

    Effects of ibrutinib and venetoclax on the expression of immune checkpoint molecules in leukemic blasts of patients with acute lymphoblastic leukemia by Armin Dozandeh-Jouybari, Fatemeh Mousavi-Mirkalaei, Saeid Taghiloo, Hossein Karami, Mohammad Naderisorki, Ehsan Zaboli, Mohammad Eslami-Jouybari, Tohid Kazemi, Hossein Asgarian-Omran

    Published 2025-06-01
    “…By elucidating the precise underlying mechanisms, these drugs could emerge as promising therapeutic options, particularly in the context of combination therapy for ALL.…”
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    Article
  5. 365

    Progress of arylacetamide deacetylase research in metabolic diseases by Liu Yang, Zhe-Zhen Liao, Li Ran, Xin-Hua Xiao

    Published 2025-05-01
    “…It plays a significant role in drug metabolism, lipid metabolism, and the pathogenesis of various diseases. In the context of drug metabolism, AADAC is vital for ensuring the safety of ester-based drugs. …”
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    Article
  6. 366

    Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

    Published 2025-03-01
    “…Overexpression of the splicing factor 3b subunit 1 (SF3B1) and neurogenic locus notch homolog protein 1 (NOTCH1) factors is typically found in chronic lymphocytic leukemia (CLL), leading to the development of chemotherapy resistance. Objective The current investigation aims to evaluate the chemosensitivity of CLL cells by blocking NOTCH1 and SF3B1 using chitosan lactate (CL) nanoparticles (NPs). …”
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    Article
  7. 367

    The Immune Environment in Colorectal Adenoma: A Systematic Review by Ugne Silinskaite, Jurate Valciukiene, Matas Jakubauskas, Tomas Poskus

    Published 2025-03-01
    “…<b>Methods:</b> In this systematic review, we aim to provide a thorough analysis of the current research examining the immune infiltration patterns in sporadic colorectal adenoma tissues in the context of immune cell-based, cytokine-based, and other immunological factor-related changes along the conventional adenoma–carcinoma sequence. …”
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  8. 368

    The role of anifrolumab in reshaping the treatment landscape of extra-renal systemic lupus erythematosus by Fulvia Ceccarelli, Matteo Piga, Alessandra Bortoluzzi, Laura Coladonato, Micaela Fredi, Daniele Mauro, Chiara Tani, Luca Iaccarino

    Published 2025-07-01
    “…Hypothetical scenarios derived from clinical practice were examined to identify real-life contexts suitable for the early initiation of anifrolumab treatment. …”
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    Article
  9. 369

    Job Satisfaction Analysis of Nurses, who Work in Neurology and Neurosurgery Units by Anna Rymkiewicz

    Published 2022-12-01
    “…Satisfaction, facing problems and motivation are currently strategic points to be analysed in terms of nurses’ work. …”
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  10. 370

    Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

    Published 2025-03-01
    “…Modification of the CCL2 secretion seemed to be context dependent in the human explants: where EVs treatment stimulated CCL2 secretion but in the presence of IL‐1β this effect was counteracted. …”
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  11. 371

    Not All Antibodies Are Created Equal: Factors That Influence Antibody Mediated Rejection by Carrie L. Butler, Nicole M. Valenzuela, Kimberly A. Thomas, Elaine F. Reed

    Published 2017-01-01
    “…This review highlights what is currently known about the clinical context of pre and posttransplant antibodies, antibody characteristics that influence AMR, and the paths after donor specific antibody production (no rejection, subclinical rejection, and clinical dysfunction with AMR).…”
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  12. 372

    Conceptual approaches to the complex of restoration of the affected territories as a result of military actions in Ukraine by Liudmyla Datsenko, Svitlana Titova, Marharyta Dubnytska

    Published 2024-07-01
    “…Results and conclusions: The land relations during the reconstruction of Ukraine should be based on the following principles and approaches: openness of the public cadastral map of Ukraine; simplification of permit procedures; assessment of land and soil quality, inventory; continuation of the trend of decreasing arable land; conservation of lands, the use of which could harm human life and health as well as the state of the environment; expropriation of land from tenants who are connected to Russia or Belarus; soil conservation in the context of war; introduction of the state system for the control of land resources and the responsibility of land users.…”
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  13. 373

    Attributing climate and weather extremes to Northern Hemisphere sea ice and terrestrial snow: progress, challenges and ways forward by Kunhui Ye, Judah Cohen, Hans W. Chen, Shiyue Zhang, Dehai Luo, Mostafa Essam Hamouda

    Published 2025-05-01
    “…Both sea ice and spring snow in the Northern Hemisphere (NH) have been decreasing at an alarming rate in a changing climate. …”
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    Article
  14. 374

    Multidisciplinary approach to the diagnosis of disorders of coagulation system in childrenwith various pathologies by O. B. Gordeeva, M. S. Karaseva, D. E. Lavretsky, M. A. Babaikina, N. D. Vashakmadze, M. A. Soloshenko, G. V. Revunenkov, E. A. Abashidze, M. V. Egorova

    Published 2023-01-01
    “…Thrombosis in children with genetically determined thrombophilia often occur in the context of risk factors. In the early neonatal period, the deficiency of anticoagulant factors manifests as the form of fulminant purpura, followed by the development of skin necrosis. …”
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  15. 375

    Legal Challenges of Marine Insurance Laws in the Use of Unmanned Ships by Mahsa Bahadoran- Baghbaderani, Masoud Shirani, Reza Soltani

    Published 2025-03-01
    “…For this reason, The study aims to address t to what extent unmanned ships can be insured within current regulations, and whether there's a necessity to modify traditional insurance principles to ensure coverage for these ships. …”
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  16. 376

    Quality failures in Energy- saving renovation projects in Northern China by Yuting Qi

    Published 2021-04-01
    “…The energy-saving renovation of an existing building is a critical strategy in achieving a long-term energy goal in the Chinese context. In response to the high energy consumption, the Chinese government encourages that the energysaving renovation projects of the existing residential buildings should be widely carry out in Northern China (Chen et al. 2015). …”
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  17. 377

    Characterizing dengue transmission in rural areas: A systematic review. by Olivia Man, Alicia Kraay, Ruth Thomas, James Trostle, Gwenyth O Lee, Charlotte Robbins, Amy C Morrison, Josefina Coloma, Joseph N S Eisenberg

    Published 2023-06-01
    “…We conducted a systematic review to synthesize research on dengue in rural areas and apply this knowledge to summarize aspects of rurality used in current epidemiological studies of DENV transmission given changing and mixed environments. …”
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    Article
  18. 378

    CIS Countries Foreign Economic Activity — from Challenges to New Opportunities by M. S. Goncharov

    Published 2024-12-01
    “…Aim and tasks. To identify current trends and issues in foreign trade, the international financial system, and the investment activity of CIS member states, and to provide recommendations that contribute to sustainable economic development and strengthened mutual cooperation.Methods. …”
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    Article
  19. 379

    Unlocking the hidden forces: deformation and associated stress distribution in the present-day Geneva Basin and Jura fold-and-thrust belt by Sandra Borderie, Jon Mosar, Adeline Marro, Louis Hauvette

    Published 2025-06-01
    “…Abstract In foreland fold-and-thrust belts, the distribution of deformation and of the associated stress field can notably be perturbed due to local-scale features such as tectonic structures or surface topography. In the context of geothermal exploration and the planning of the future circular collider (CERN) in the Geneva Basin, it is of particular interest to constrain possible future deformation in the area and the associated stress state. …”
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    Article
  20. 380

    Effectiveness of Nursing Intervention Protocol on Nurses’ Performance and Patients’ Self-Care after Cataract Surgery by Amal S. Taha

    Published 2024-04-01
    “… Context: Cataract is the leading cause of poor vision worldwide. …”
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    Article