The pharmacological management of depression – Update 2017 by Elzbieta Osuch, Andre Marais

“…Depressive disorders contribute significantly towards overall morbidity and increased risk for suicide. Antidepressant therapy remains one of the cornerstones in the management of depressive disorders. …”
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Early Diagnosis of Latent Tuberculosis Reactivation due to Drug Interaction between Cobicistat and Intranasal Fluticasone by Roberto Pineda-Reyes, Alena Klochko

“…Single-tablet antiretroviral therapy is currently the first-line choice for the treatment of HIV infection. …”
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Unveiling biomarkers via plasma metabolome profiling for diabetic macrovascular and microvascular complications by Zhixi Li, Yuhan Ren, Feng Jiang, Kai Zhang, Xuan Meng, Yingfeng Zheng, Mingguang He

“…In contrast, the potential prognostic value of the plasma metabolome remains substantially under characterized in this context. This study aims to systemically reframe the value of circulating metabolites, providing new insights into both assessment and pathophysiology of diabetic complications. …”
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Influence of the Electric Field on the Properties of Hydrogenated Graphene by V. V. Muravyov, V. N. Mishchenka

“…Graphene is currently considered as one of the most promising materials for the creation of new semiconductor devices for various frequency ranges. …”
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Performance of epoxy-nanocomposite under corrosive environment

“…The diffusion of the environmental solution was measured by noting the increase in weight of the samples as a function of immersion time in these solutions at 80°C. …”
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Substance P- and Insulin-like Growth Factor 1-derived Tetrapeptides for Neurotrophic Keratopathy Related to Leprosy: A Clinical Trial by Shoko Kondo, MD, Yoshiko Okano, MD, PhD, Satoshi Iraha, MD, PhD, Shoji Tokunaga, PhD

“…Although leprosy is bacteriologically curable, there is currently no efficient treatment. Eye drops containing tetrapeptides, phenylalanine-glycine-leucine-methionine-amide (FGLM-NH2) and serine-serine-serine-arginine (SSSR), derived from substance P and insulin-like growth factor 1, are clinically efficacious in the treatment of corneal epithelial disorders caused by neurotrophic keratopathy. …”
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From waste to weapon: the potential of medicinal plant waste extracts for eco-friendly crop disease management by Chang-Jie Jiang, Yao Sun, Shijiao Xu, Shijiao Xu, Xinqiong Liu, Xianzhi Xie

“…The increasing challenge of managing crop diseases requires innovative and sustainable approaches. …”
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Changes in the Species Composition and Structure of Large-Diameter Trees Along a Narrow Latitudinal Gradient in Subtropical China by Mengxian Li, Fei Huang, Xiaorong Jia

“…Investigating these impacts provides critical insights for silvicultural species selection and forest structure optimization, particularly in the context of global warming, and is essential for the sustainable development of large-diameter forests. …”
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Transition Effects in Bridge Structures and Their Possible Reduction Using Recycled Materials by Mariusz Spyrowski, Krzysztof Adam Ostrowski, Kazimierz Furtak

“…This article serves as a review of the current challenges in bridge engineering, specifically addressing the transition effect and the utilization of recycled materials. …”
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Sustainable Machining Using Eco-Friendly Cutting Fluids: A Review by Pankaj Kumar, Amit Kumar Jain, Prem Kumar Chaurasiya, Damodar Tiwari, Anitha Gopalan, Joshuva Arockia Dhanraj, Jenoris Muthiya Solomon, Aravinth Sivakumar, Karthikeyan Velmurugan, Johannex Fefeh Rushman

“…The base fluids of eco-friendly cutting fluids should contain some vegetable oil. Due to their eco-friendly, thermal, and tribological qualities, these types of machining fluids are becoming increasingly popular among researchers throughout the world. …”
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Mapping the status of global taxonomic knowledge of Orthoptera (Arthropoda, Insecta) by Rodrigo Antônio Castro-Souza, Juliana Stropp, Luiz Felipe Moretti Iniesta, Richard J. Ladle, Neucir Szinwelski, Geiziane Tessarolo, José Alexandre Diniz-Filho, Thadeu Sobral-Souza, Joaquín Hortal

“…Our analyses show that the descriptions of currently valid species increased exponentially since the 19th century, with a temporary decline following World War II, while synonyms outpaced the number of valid species until the 1980s. …”
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The Potential of Plant Extracts Used in Cosmetic Product Applications—Antioxidants Delivery and Mechanism of Actions by Cristina-Ştefania Gǎlbǎu, Marius Irimie, Andrea Elena Neculau, Lorena Dima, Lea Pogačnik da Silva, Mihai Vârciu, Mihaela Badea

“…Plant materials are becoming increasingly popular as natural antioxidants related to the expanding interest in plant chemistry. …”
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The Impact of Low-Level Laser Therapy on Spasticity in Children with Spastic Cerebral Palsy: A Systematic Review by Amalio Jiménez, Frederick R. Carrick, Norman Hoffman, Monèm Jemni

“…Context: Spastic cerebral palsy (SCP) is a condition characterized by muscle stiffness and involuntary movements, which greatly affect movement abilities and overall well-being. …”
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Application of dynamic systems modeling approach to rank optimal urban waste management strategies using SWOT method by Hamid Shahbandarzadeh, Mohammad Hossein Kabgani

“…This approach shows that among SO strategies, increasing awareness and changing citizens' attitudes towards proper waste management is in the first place. …”
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PRODUCTION PROSTHETIC NOSE FOR CAD / CAM TECHNOLOGY: ADVANTAGES AND DISADVANTAGES by L.B. Yerys

“…CAD / CAM technologies are increasingly used in prosthetic dentistry, including the manufacture of artificial limbs ear, nose, orbit, upper and lower jaw. …”
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Novel Hypericin-loaded nanoparticles as a new drug delivery system ameliorate olanzapine-induced early renal injury and oxidative stress: In vitro and in vivo approaches by Abeer M. Abd El-Hameed, Fatimah A.R. AbdulAlim, Amal H. Alsehli, Fadwa A. Elroby

“…The HP-SiNPs release profile, entrapment efficiency, cytotoxicity against the Vero cell line, renal function parameters, antioxidant efficacy, and histological changes in male rats administered with OLZ were all investigated, and they were compared to those of free HP.XRD reveals the development of an HP-silica-based composite with a 275.0 nm particle size, which increases BET surface area and thermal stability. An entrapment efficiency of around 95.61 ± 0.28 %, and a prolonged release of less than 20 % after 12 h were validated by the current results. …”
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Circulating Cell-free Tumor Nucleic Acids in Gastric Cancer by Hyun-Ji Lee, Sun Min Lee

“…As these new blood-based biomarkers have attracted increasing attention, we have discussed several important points to be considered before the clinical translation of ctNA detection. …”
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Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors by Alfred Zippelius, Petra Herzig, Pratiksha Gulati, Christian Klein, Marta Trüb, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Marina Natoli, Klas Hatje, Fabian Junker, Zhiwen Jiang, Iakov I Davydov, Markus Germann, Daniel Marbach, Adrian Zwick, Patrick Weber, Stefan Seeber, Lothar Tietze, Laura Codarri-Deak, Henry Kao

“…Bispecific antibodies, but not anti-PD-1, significantly increased the abundance of a proliferating natural killer cell subset, which exhibited enrichment for a tissue-residency signature. …”
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A review of the foliar application of individual amino acids as biostimulants in plants by Bethany C. R. Henderson, John M. Sanderson, Andrew Fowles

“…This review summarises current knowledge on the effects of the foliar application of the 20 most common naturally occurring amino acids. …”
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Preserving Innovation: Ensuring the Future of Today’s Scholarship by Karen L Hanson

“…Scholars are experimenting with increasingly diverse digital technologies to express their research in new ways. …”
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