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4601
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4602
Gene Editing Anxiety
Published 2025-05-01“…Health and Genetic Risks of Germline Editing Editing the human germline to prevent psychiatric disorders poses serious health risks to individuals. Currently, scientists warn that genetically altering the human genome can result in off-target mutations that increase the risk of disease. …”
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4603
Development of a composite material based on a processed product of agricultural crop
Published 2024-10-01“…Anthropogenic influence on the environment contributes to an increase in the content of heavy metals in soils. This is facilitated by the developed industrial sector, high population density and large-scale growth of urban areas. …”
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4604
Research progress on the control of reactive elements in remelted ingots during the electroslag remelting process
Published 2025-05-01“…Additionally, the physical parameters of the slag system play a crucial role in determining the surface quality and solidification characteristics of the ingots. Current research on the physical parameters of remelting slag systems containing TiO2, SiO2, B2O3, and rare earth oxides has primarily focused on viscosity and crystallization behavior. …”
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4605
Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis
Published 2025-07-01“…Abstract Facet joint osteoarthritis (FJOA) is a prevalent degenerative condition in the aging population; however, the underlying pathophysiological mechanisms remain poorly understood and current therapeutic strategies remain limited to palliative pain management. …”
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4606
Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer
Published 2025-01-01“…Moreover, pixels in each whole-mount slide of PCa are increased by approximately <inline-formula> <tex-math notation="LaTeX">$4\sim 9$ </tex-math></inline-formula> times, therefore containing more information for diagnosis. …”
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4607
What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey
Published 2024-10-01“…Most patients were offered the flu jab. Older patients, current smokers and those with other conditions such as heart failure had higher risk of an acute exacerbation. …”
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4608
Home Health Care Providers’ Readiness to Care for Children and Youth With Complex Medical Conditions: Protocol for a Scoping Review
Published 2025-07-01“…However, families continue providing the bulk of care, often at great personal costs. As care complexity increases, so does the reliance on home care providers. …”
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4609
Research status and prospects of treatment for malignant pleural mesothelioma
Published 2025-03-01“…Malignant pleural mesothelioma (MPM) is strongly associated with a history of asbestos exposure and is characterized by high malignancy, high mortality, and poor prognosis. Current treatments for MPM are limited and generally suboptimal, resulting in a median overall survival (OS) of approximately one year for MPM patients. …”
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4610
Student Mental Health in UK Higher Education Institutions: Protocol for a Scoping Review of Trends, Gaps, and Research Directions
Published 2025-07-01“…Current literature remains fragmented, with limited synthesis comparing national contexts. …”
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4611
Incidence and trends of limb amputation in first nations and general population in Saskatchewan, 2006-2019.
Published 2021-01-01“…Overall and primary LA rates for the GP Group declined 0.7% and 1.0%, while subsequent LA increased 0.1%. An increased LA rate for all categories (overall 4.9%, primary 5.1%, and subsequent 4.6%) was identified in the RI group. …”
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4612
Features of “Inverted” Educational Resources for Distance Learning of Pupils
Published 2021-08-01“…The main idea behind the development of such tools is that the “inverted” learning resources, on the one hand, implement a non-linear approach to the implementation of learning activities in accordance with the individual characteristics of a particular student (the current level of training, knowledge gaps, specific interests and difficulties), with the other - they create conditions for the initial systematization and complex internalization of the acquired knowledge and methods of action, contain a “cognitive challenge” aimed at increasing educational motivation through the implementation of mechanisms of formative self-control at the initial stage. …”
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4613
Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extracts against TCDD-induced hepatocyte damage in Jian carp (Cyprinus carpio var. Jian)
Published 2015-09-01“…Jian).Jian carp were fed with diet containing 3 doses of GGE (0.1, 0.5 and 1.0 g/kg diet) for 60 days before a single intraperitoneal injection of TCDD (0.6 μg/kg), 72 h after TCDD injection, blood and liver samples were taken for biochemical analysis.The results showed that GGE at 1.0 g/kg diet for 60 days prior to TCDD intoxication significantly reduced the elevated activities of ALT, AST, LDH, AKP and increased the reduced levels of total protein (TP), albumin (Alb) in the serum, markedly inhibited the reduction of the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), total antioxidant capacity (T-AOC), and reduced the malondialdehyde (MDA) formation in liver tissue. …”
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4614
Anatomy and function of closing muscle complex of the vagina in health and pelvic organ prolapse
Published 2025-07-01“…In modern literature, the pelvic floor muscles are presented by showing their anatomical location and indicating relevant attachment points, but their combined anatomical, topographic and functional significance is described insufficiently, which the current review was aimed at.Aim: to determine the physiological significance and anatomical units of the vagina occlusor muscle complex, topography and functions in health and in pelvic organ prolapse (POP).Materials and Methods. …”
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4615
Antiviral Therapeutics Discovery for Enterovirus D68.
Published 2025-03-01“…To date, there are no effective antiviral successfully developed for enterovirus infection and the current understanding on pathogenesis is limited, which has resulted in the persistent circulation and outbreaks across the globe. …”
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4616
Using the Smath Computer Package in School Mathematics Lessons
Published 2025-03-01“…Examples include linear equations and their systems, quadratic equations, equations containing modules, and text problems leading to the construction of equations. …”
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4617
Shaping the future of nanotechnology: a perspective on education, dissemination and ethics
Published 2025-05-01“…We analyze the available tools and highlight the current state of nanodissemination through a comprehensive review of mature and successful dissemination initiatives in nanosciences and nanotechnologies. …”
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4618
An animal model study of simplified optical navigation system-assisted percutaneous lumbar transforaminal puncture
Published 2025-08-01“…The system significantly improves puncture accuracy while markedly decreasing both the number of puncture attempts and fluoroscopy exposures compared to conventional techniques.…”
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4619
Immune status changes in patients with phlegmon in the maxillofacial region relation with purulent process prevalence
Published 2016-01-01“…Serum IL4 concentration was increased only in patient with pyoinflammatory changes in more than one area. …”
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4620
The possibility of using the DKS-AT1123 dosimeter for radiation monitoring of medical electron accelerators with the energy of more than 10 MeV
Published 2024-07-01“…Over the past 4 years, their number has increased 2.5 times. These installations contain pulsed electron accelerators that generate pulsed bremsstrahlung radiation with a maximum energy from 6 to 21 MeV. …”
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