MicroRNA-32-5p inhibits metastasis by directly targeting VPS4B and increases sensitivity to dihydroartemisinin in neuroblastoma by Lina Chen, Hui Liu, Zhongyuan Zheng, Shuiqing Qu, Yu Zhang, Shuoqiu Deng, Shuo Shen, Tuo Liu, Yue Dai, Yu Li, Honghua Cui, Yujie Li

“…The primary objective of the current investigation was to characterize a newly discovered microRNA, miR-32-5p, in terms of the functional role, underlying mechanism of action, and potential synergistic therapeutic impact in the context of NB metastasis. …”
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Increasing uptake of self-management education programmes for type 2 diabetes in primary care: the Embedding research programme including an RCT by Melanie J Davies, Shona Agarwal, Danielle H Bodicoat, Alan Brennan, Simon Dixon, Helen Eborall, Agnieszka Glab, Laura J Gray, Michelle Hadjiconstantinou, Lisa Huddlestone, Nicky Hudson, Anju Keetharuth, Kamlesh Khunti, Caroline Kristunas, Graham Martin, Alison Northern, Mike Patterson, Daniel Pollard, Rebecca Pritchard, Sally Schreder, Jane Speight, Bernie Stribling, Jackie Sturt, Jess Turner, Christina Weis

“…Key recommendations for research Consider how best to increase uptake to SSME within the new context of increased focus on digital/virtual modalities due in part to the COVID-19 pandemic, while maintaining the benefits to some underserved populations without alienating others and widening disparities (e.g. those without internet access). …”
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Main factors influencing the digital economy: a literature review by Heng Zhang

“…In response to the challenges of our time, our research aims to understand and analyse the trends of digitalization of the economy in the current context. It is important to note that this topic is becoming increasingly relevant in the context of the rapid development of technology and its impact on the global economy as a whole. …”
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Process evaluation of a cluster randomised implementation trial examining strategies to increase early access to exercise for people with knee osteoarthritis: protocol by Jocelyn L Bowden, Kathryn Mills, Justine M Naylor, Joseph Descallar, Robert Boland, Margery Pardey, Amy Orsatti

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The molecular mechanism of shade avoidance in crops – How data from Arabidopsis can help to identify targets for increasing yield and biomass production by Yun-jia TANG, Johannes Liesche

“…This shade avoidance response (SAR) typically includes increased stem elongation at the expense of plant fitness and yield, making it an undesirable trait in an agricultural context. …”
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CALCULATION OF STATIC PARAMETERS OF SILICON DIODE CONTAINING δ-LAYER OF TRIPLE-CHARGED POINT DEFECTS IN SYMMETRIC p–n-JUNCTION by N. A. Poklonski, A. I. Kovalev, N. I. Gorbachuk, S. V. Shpakovski

“…The static capacityvoltage and current-voltage characteristics of the silicon diode with nondegenerate regions of pand n-type of electrical conductivity are calculated for forward and reverse electric bias voltage.It is shown by calculation that in the p–t–n-diode containing the δ-layer of t-defects, at the forward bias a region of current density stabilization occurs. …”
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CURRENT APPROACH TO DEVELOPMENT OF BIOSIMILAR PRODUCTS CONTAINING MONOCLONAL ANTIBODIES AS AN ACTIVE SUBSTANCE – NON-CLINICAL AND CLINICAL STUDIES OF THE FIRST RUSSIAN RITUXIMAB BI... by S. M. Alekseev, K. D. Kaplanov, R. A. Ivanov, E. V. Chernyaeva

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Increasing our knowledge about the epidemiology of Helicobacter pylori in Nunavik’s Inuit population (Québec, Canada) using Qanuilirpitaa? 2017 cross-sectional survey by Julie Ducrocq, Benoit Lévesque, Gaston De Serres, Véronique Boiteau, Cedric P. Yansouni, Jean-François Proulx, Denis Talbot

“…Despite current regional guidelines targeting high risk individuals in the context of high prevalence, Nunavik’s health authorities must remain vigilant by following gastric cancer incidence and the rapid evolution of guidelines, while considering local realities.…”
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Short Interfering RNA Directed against the SLUG Gene Increases Cell Death Induction in Human Melanoma Cell Lines Exposed to Cisplatin and Fotemustine by Ivan Vannini, Massimiliano Bonafe, Anna Tesei, Marco Rosetti, Francesco Fabbri, Gianluca Storci, Paola Ulivi, Giovanni Brigliadori, Dino Amadori, Wainer Zoli

“…Background: Melanoma remains largely resistant to currently available chemotherapy, and new strategies have been proposed to flank standardized therapeutic protocols in an effort to improve efficacy. …”
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A Computational Approach to Increasing the Antenna System’s Sensitivity in a Doppler Radar Designed to Detect Human Vital Signs in the UHF-SHF Frequency Ranges by David Vatamanu, Simona Miclaus

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Trusted health system implementation strategies to increase vaccination (TRUE SYNERGI): a stepped-wedge cluster randomized trial to reduce HPV-related cancers by Daisy Y. Morales-Campos, Prajakta Adsul, Yuanyuan Liang, Erin Donovan, Leticia R. Moczygemba, Jessica A. Kahn

“…Preliminary data from our previous work suggest practice facilitation is a feasible approach for building the capacity in FQHCs to select and implement provider- and practice-level strategies for increasing vaccination rates. Methods This proposal considers the HPV vaccine as the evidence-based intervention and describes the rational and study design for “TRUsted hEalth SYstem implementatioN stratEGIes to increase vaccination (TRUE SYNERGI)”, a hybrid type 2 study that uses previously-piloted implementation strategies (i.e., practice facilitation, provider education, among others) to influence provider recommendations (implementation outcome) and practice-level vaccination rates (effectiveness outcome). …”
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Study protocol for an observational research study with an embedded N-of-1 design: Increasing the availability of goal-oriented cognitive rehabilitation for people living with deme... by Caoimhe Hannigan, Antoine Lemercier, Garret McDermott, Helena Lydon, Sean P Kennelly, Michelle Kelly

“…Sub-study 1 will evaluate the impact of GREAT-CR in this context and sub-study 2 will evaluate the implementation model. …”
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The Impact of Increasing Seawater Temperatures over the Last 30 Years on the Reproductive Cycle of the Pearl Oyster <i>Pinctada radiata</i> (Leach, 1814) in the Arabian Gulf by Razan Khalifa, Radhouane Ben Hamadou, Bruno Welter Giraldes, Sandra Joaquim, Zainab Hizam, Shafeeq Hamza, Anne Bassères, Jean-Charles Massabuau, Alexandra Leitão

“…This study aimed to characterize the reproductive cycle of <i>P. radiata</i> in Qatar and compare the current data with historical records in the region obtained between 1992 and 1993. …”
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The Functional Impact of VX-770 on the Cystic Fibrosis Transmembrane Conductance Regulator Is Enduring and Increases the Constitutive Activity of This Channel in Primary Airway Epi... by Heidi J. Nick, Sarah E. Christeson, Preston E. Bratcher

“…Acute VX-770 exposure resulted in an increase in CFTR-mediated currents in the absence of exogenous compounds that induce the phosphorylation/activation of CFTR, with acute exposure having the same effect as chronic exposure. …”
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Increasing day three parasitaemia is observed after treatment of patients with artemether-lumefantrine and single dose of primaquine for uncomplicated Plasmodium falciparum malaria... by Bontu Abate, Bokretsion Gidey Brhane, Tsegahun Manyazewal, Hussien Mohammed, Yonas Wuletaw, Moges Kassa, Mesay Hailu, Getachew Tollera, Geremew Tasew, Ashenafi Assefa, Eyasu Makonnen

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A multi-level implementation strategy to increase adoption of chiropractic care for low back pain in primary care clinics: a randomized stepped-wedge pilot study protocol by Eric J. Roseen, André Bussières, Rocky Reichman, Celia Bora, Jennifer Trieu, Kirsten Austad, Charles Williams, Ryan A. Fischer, Danielle Parrilla, Lance D. Laird, Michael LaValley, Roni L. Evans, Robert B. Saper, Natalia E. Morone

“…., manual therapy, exercise instruction, advice on self-care), implementation strategies to increase adoption of chiropractic care for LBP in primary care clinics are understudied, particularly in underserved communities. …”
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Feasibility of Cognitive Training in Combination With Transcranial Direct Current Stimulation in a Home-Based Context (TrainStim-Home): study protocol for a randomised controlled t... by Ulrike Grittner, Agnes Flöel, Rafal Nowak, Friederike Thams, Daria Antonenko, Merle Rocke, Robert Malinowski

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INNOVATIONS IN NUTRITION AS RISK-DECREASING FACTOR OF ALIMENTARY-DEPENDENT DISEASES IN INFANTS by T.V. Borodulina, N.E. Sannikova, L.N. Malyamova

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Aplikasi belajar tajwid menggunakan binary search by Anita Andriani, Arbiati Faizah, Indana Lazulfa, Istiqomah Istiqomah

“…Muslim start learning tajweed from their early age, but currently motivation to learn tajweed is decreasing. …”
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Generating evidence on screening, diagnosis and management of non-communicable diseases during pregnancy; a scoping review of current gap and practice in India with a comparison of... by Theophilus Lakiang, Sonali Abner Daniel, Kauma Kurian C, Minashree Horo, Shumayla Shumayla, Sunil Mehra

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