Therapeutic potential of microRNAs in neurological disorders: mechanisms, biomarkers, and emerging therapeutic strategies by Sourav Pal, Subhajit Mandal

“…This review critically evaluates current therapeutic strategies for miRNA delivery in neurological disorders, focusing on advanced platforms such as nanocarriers, exosomes, viral vectors, and ligand-mediated systems designed to overcome the blood-brain barrier. …”
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Theoretical Research on the Shear Mechanical Properties and Size Effect of Recycled Concrete Beams Without Stirrups by Chunyang Liu, Guangkai Zhou, Hao Wang, Yilin Wang

“…As a new type of building material with great potential, recycled concrete is playing a vital role in the context of the current construction industry’s pursuit of sustainable development. …”
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Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade by Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler

“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
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Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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Recent process in organic near-infrared fluorescent probes for detecting hypochlorous acid/hypochlorite by Zhongchang Wang, Chenzheng Guan, Wenxu Lu, Liangchao Yuan, Man Chao, Hai-Liang Zhu, Tingwu Liu

“…The design of NIR-HClO fluorescent probes has garnered increasing research focus. This review provides a critical evaluation of the latest advances (2021–2025) in the design and construction of organic NIR fluorescent probes for selectively monitoring HClO. …”
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Cybersecurity requirements for medical devices in the EU and US - A comparison and gap analysis of the MDCG 2019–16 and FDA premarket cybersecurity guidance by Max Ostermann, Rebecca Mathias, Fatemeh Jahed, Mitchell B. Parker, Florence D. Hudson, William C. Harding, Stephen Gilbert, Oscar Freyer

“…The increasing use of connected medical devices has led to substantial cybersecurity challenges, putting patient safety and the integrity of healthcare infrastructures at risk. …”
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Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4 by Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao

“…Hypoxia-inducible factor-1 (HIF-1) activation plays an essential role in CKD; however, the specific contribution of tubular HIF-1 to renal TIF remains unclear. In the current study, the mechanism underlying HIF-1-mediated TIF was investigated. …”
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Contextual Vulnerability Should Guide Fair Subject Selection in Xenotransplantation Clinical Trials by Gianna Strand

“…This paper describes the current transplant system’s use of subjective evaluation criteria, particularly psychosocial support and compliance. …”
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Graded Roll‐to‐Roll Slot Die Coating for High‐Throughput Catalyst Layer Studies by George Pätzold, Maximilian Maier, Lukas Löttert, Anna T. S. Freiberg, Prof. Dr. Simon Thiele, Dr. Dominik Dworschak

“…Many of these systems are based on substrates coated with thin layers containing catalyst, ionomer or support material like carbon. …”
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Performance Characteristics of a Pilot-Scale Electromethanogenic Reactor Treating Brewery Wastewater by Kyle Bowman, Marcelo Elaiuy, George Fudge, Harvey Rutland, William Gambier, Theo Hembury, Ben Jobling-Purser, Thomas Fudge, Izzet Kale, Godfrey Kyazze

“…This investigation presents a 4-fold increase in size compared to the next largest pilot-scale MEC-AD system presented in the literature, providing findings to inform the operation of a 52,000 L MEC-AD system (currently under construction). …”
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A New Source of Inoculum for <i>Stemphylium vesicarium</i>: Consequences for the Management of Brown Spot of Pear by Federico Cavina, Serena Baiocco, Lorenzo Tomba, Fabio Ravaglia, Christian Moretti, Rosario Raso, Valentino Giorgio Rettore, Martina Parrilli, Gianfranco Pradolesi, Riccardo Bugiani

“…Brown spot of pear (BSP), caused by <i>Stemphylium vesicarium</i>, is one of the most dangerous pear fungal diseases, being responsible for huge losses in production. Currently, in order to increase its containment, chemical control is implemented in conjunction with agronomic techniques able to reduce BSP inoculum sources (e.g., orchard grass sanitation, litter removal or application of biocontrol agents). …”
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Effects of Dynamic Agrivoltaics on Containerized Raspberry Plants: Results of the First Season by Perrine Juillion, Candice Tranchant, Kaoutar Nadi, Jimmy Noel, Benoit Valle, Jérôme Chopard, Gerardo Lopez, Camille Crevat, Xavier Bunker, Damien Fumey

“…The protection from the DAV reduced mean air temperature by 1.8°C and increased mean relative humidity by 7.3% in comparison to the CTL. …”
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The state of drained peatlands in the Middle Urals and prospects of their use for carbon farming by Seyed Omid Reza Shobairi, Alenakochubei, Olga Cherepanova, et al.

“…The global change of the planet's climate is associated with increased concentration of greenhouse gases in the atmosphere, which is the result of irrational human economic activity. …”
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Role of tertiary lymphoid structures and B cells in clinical immunotherapy of gastric cancer by Weiyi Chen, Lingli Zhang, Man Gao, Ning Zhang, Rumeng Wang, Yang Liu, Yan Niu, Lizhou Jia, Lizhou Jia

“…In recent years, the role of various immune cells in the tumor microenvironment in cancer progression and treatment has gained increasing attention. Immunotherapy, primarily based on immune checkpoint inhibitors, has notably improved the prognosis of patients with gastric cancer; however, challenges regarding therapeutic efficacy persist. …”
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Fatty fried food toxins as triggering stimuli to immune system interplay in global autoimmune diseases: A systematic review by Saba Anwar, Qamar Abbas Syed, Mahnoor Saleh, Muhammad Saad Akram, Ghayyor Sultan, Sahar Khalid, Anum Ishaq, Gholamreza Abdi, Rana Muhammad Aadil

“…Although the scientific evidence on this topic has not been thoroughly studied, the studies reviewed confirmed the potential role of fast foods in increasing the incidence of autoimmune diseases.…”
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Job insecurity, work passion, and work–life balance in diverse work arrangements by Chantell Ribas, Gerhard H. Rabie, Karina Mostert, Leon De Beer

“…Orientation: The coronavirus disease 2019 (COVID-19) pandemic shifted work settings, revealing gaps in current literature on how work arrangements affect employee experiences and well-being. …”
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Optimizing AI models to predict esophageal squamous cell carcinoma risk by incorporating small datasets of soft palate images by Kotaro Waki, Katsuya Nagaoka, Keishi Okubo, Masato Kiyama, Ryosuke Gushima, Kento Ohno, Munenori Honda, Akira Yamasaki, Kenshi Matsuno, Yoki Furuta, Hideaki Miyamoto, Hideaki Naoe, Motoki Amagasaki, Yasuhito Tanaka

“…Previously, we found that specific soft palate morphologies are strongly associated with increased ESCC risk. However, there is currently no artificial intelligence (AI) system that utilizes oral images for ESCC risk assessment. …”
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CREATING THE KULTUK POLYGON FOR EARTHQUAKE PREDICTION: VARIATIONS OF (234U/238U) AND 87SR/86SR IN GROUNDWATER FROM ACTIVE FAULTS AT THE WESTERN SHORE OF LAKE BAIKAL by S. V. Rasskazov, E. P. Chebykin, A. M. Ilyasova, E. N. Vodneva, I. S. Chuvashova, S. A. Bornyakov, A. K. Seminsky, S. V. Snopkov, V. V. Chechel'nitsky, N. A. Gileva

“…Determinations of (234U/238U) in groundwater samples are used for monitoring current deformations in active faults (parentheses denote activity ratio units). …”
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Plant Cell Culture-Derived Saponin Adjuvant Enhances Immune Response Against a Stabilized Human Metapneumovirus Pre-Fusion Vaccine Candidate by Maarten Swart, Jessica Allen, Brendan Reed, Ana Izquierdo Gil, Johan Verspuij, Sonja Schmit-Tillemans, Anish Chakkumkal, Mark Findeis, Angela V. Hafner, Chandresh Harjivan, Rebecca Kurnat, Harmjan Kuipers, Roland Zahn, Boerries Brandenburg

“…Results: In mice, TLR4 agonist containing adjuvant formulations with plant cell-produced QS-21 performed equally to licensed adjuvant AS01 containing tree-bark-extracted QS-21 and demonstrated a significant increase in immunogenicity against HMPV preF compared to the unadjuvanted control. …”
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Podcasts in Mental, Physical, or Combined Health Interventions for Adults: Scoping Review by Elizabeth M Dascombe, Philip J Morgan, Ryan J Drew, Casey P Regan, Gabrielle M Turner-McGrievy, Myles D Young

“… BackgroundThe increasing prevalence of poor mental and physical health in adults is a global health concern. …”
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