What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey by Alex Bottle, Alex Adamson, Xiubin Zhang, Benedict Hayhoe, Jennifer K Quint

“…Clinical Practice Research Datalink analysis showed notable changes in post-diagnosis prescribing from cohort 1 to 2, such as increases in long-acting muscarinic antagonist (21.7–46.3%). …”
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Electronic cigarette use in relation to changes in smoking status and respiratory symptoms by Linnéa Hedman<sup>+<sup>, Gustaf Lyytinen<sup>+<sup>, Helena Backman, Magnus Lundbäck, Caroline Stridsman, Anne Lindberg, Hannu Kankaanranta, Lina Rönnebjerg, Eva Rönmark, Linda Ekerljung

“…A validated postal questionnaire containing identical questions was used in OLIN and WSAS at baseline in 2006–2008 and at follow-up in 2016. …”
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Why a strong global plastics treaty is essential for agricultural systems, food safety, food security and human health by Marie-France Dignac, Melissa Bakhos, Susanne Brander, Gabin Colombini, Megan Deeney, Etienne Dufour, Violette Geissen, Asta Hooge, Esperanza Huerta Lwanga, Baptiste Monsaingeon, Kristian Syberg, Joe Yates

“…An ambitious global plastics treaty is urgently needed to decrease soil pollution from microplastics and nanoplastics (MNPs), originating both from intentional uses of agricultural plastics and from composts and sludges applied to soils, contaminated due to the increasing plastic production and use. The current narrative, biased by vested interests, overemphasizes short-term benefits of agricultural plastics, while ignoring their adverse effects. …”
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Isolation of mitogen-activated protein kinase SlMAPK12 gene and characterization of its expression pattern in Solanum lycopersicum by KONG Fu-ling, WANG Jie, CHENG Lin, GUAN Xiao-yan, HE Yan-jun, LU Gang

“…As we know, current research on tomato (Solanum lycopersicum L.) …”
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THE ETHICAL STARTUP? by Alexis Walker

“…While this may seem counterproductive to current business goals, the very emergence of DNA marketplaces selling themselves as equitable and just alternatives to older models suggests that ethical practice can increasingly be seen as a selling point for some companies. …”
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Clinical and laboratory assessment of the effect of hygiene products on the condition of periodontal tissues and hard tooth tissues in the treatment of caries by indirect method by I. A. Belenova, V. A. Mitronin, Z. A. Filippova, V. I. Khryachkov, M. S. Vasilyeva, N. A. Protsenko

“…According to statistics, the widespread use in modern dental practice of indirect restoration methods in the treatment of caries of the frontal group of teeth leads to an increase in the incidence of marginal periodontal disease. …”
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The impact of electronic cigarette smoking on periodontal status and proinflammatory cytokine levels: a cross-sectional study by Banna Alnufaiy, Hanadi Ghurmallah Alzahrani, Rhodanne A. Lambarte, Mohannad Abdullah Alghamdi, Abdulelah Saad Alali, Wael Farhan Alanazi, Mohammad Hamad Alkanhal, Abdulrahman Farhan Almukhalfi

“…Abstract Background E-cigs(E-cigs) use is increasing worldwide. Recent studies suggest that E-cigs contain harmful elements that could lead to adverse oral health outcomes. …”
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Improved Mechanical Performances of Hastelloy C276 Composite Coatings Reinforced with SiC by Laser Cladding by Yuqing Tang, Zheng Lu, Xuan Zhang, Xihuai Wang, Shengbin Zhao, Mingdi Wang

“…SiC addition resulted in the formation of high-hardness phases, such as Cr₃Si and S₅C₃, with their peak intensity increasing with SiC content. The dendrites extend from the bonding zone towards the top of the coatings, and the crystal direction diffuses from the bottom to each area. …”
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Aortic Aneurysm Inflammatory Cell Detection with Deep Learning methods by Kristóf-Gergö Nagy, Csaba Szferle, Attila Fintha

“…INTRODUCTION: In digital pathology, neural networks such as the Multilayer Perceptron (MLP) and Residual Neural Network (ResNet) are becoming increasingly prevalent for the analysis of tissue structure. …”
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Construction of Modified Mesoporous Graphite Phase Carbon Nitride Material and Its Photocatalytic U(Ⅵ) Reduction Performance by YU Mingyue1, HAO Shuai1, HUANG Wenlong1, JIANG Dongmei2, XIA Liangshu1

“…Consequently, the uranium-containing wastewater produced poses significant and substantial threats to environmental safety and public health. …”
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Integrating quantum synchronization in future generation networks by Swaraj Shekhar Nande, Muhammad Idham Habibie, Milad Ghadimi, Andrea Garbugli, Koteswararao Kondepu, Riccardo Bassoli, Frank H. P. Fitzek

“…However, existing standards, such as the precision time protocol, are unreliable due to jitters, datagram losses, and complexity. Increasing the synchronization error from the ideal tens of nanoseconds to hundreds of microseconds is unacceptable in future-generation networks. …”
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Epidemiological Situation on Cholera in the Russian Federation in 2023 and Forecast for 2024 by A. Yu. Popova, A. K. Noskov, E. B. Ezhlova, V. D. Kruglikov, E. V. Monakhova, O. S. Chemisova, A. A. Lopatin, S. M. Ivanova, O. A. Podoynitsyna, A. S. Vodop’yanov, D. A. Levchenko, I. V. Savina

“…It was established that the toxigenic strains isolated from patients belonged to the currently dominant in the world “post-Haitian” group, including in India and Bangladesh, with the genotype ctxB7 tcpACIRS rtxA4a VSP-IIΔ0495-0512. …”
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Investigating The Possibility of Extracting Phenolic Compounds from Raisin Waste with The Aim of Waste Management from Raisin Processing Units by Amir Abbas Matin, Bahar Azimi, Hosein Hashempoor

“…Introduction: Grapes are one of the most important and most productive agricultural harvests in the world. Iran is currently the seventh largest producer of grapes in the world, with over 252,000 hectares of vineyards. …”
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Rapid public health genomics capacity building during the COVID-19 Delta crisis driven by a transnational private, public, and social alliance by Mehul Champaklal Mehta, Mehul Champaklal Mehta, Mehul Champaklal Mehta, Gayatri Nair Lobo, Gayatri Nair Lobo, Gretchen Weightman, Gretchen Weightman, Vidushi Chitalia, Vidushi Chitalia, Jayanthi Shastri, Jayanthi Shastri, Jayanthi Shastri

“…The percentage of samples sequenced increased from less than 1% to over 30%, including all known RT-PCR positive cases, the sequencing time dropped to under 72 h, and public health policy and responses were enhanced. …”
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Investigation of neuromodulation of the endbulb of Held synapse in the cochlear nucleus by serotonin and norepinephrine by Maria Groshkova, Maria Groshkova, Maria Groshkova, Maria Groshkova, Maria Groshkova, Theocharis Alvanos, Theocharis Alvanos, Theocharis Alvanos, Yumeng Qi, Fangfang Wang, Carolin Wichmann, Carolin Wichmann, Carolin Wichmann, Carolin Wichmann, Yunfeng Hua, Tobias Moser, Tobias Moser, Tobias Moser, Tobias Moser, Tobias Moser, Tobias Moser

“…Patch-clamp recordings from BCs revealed an increase in frequency of miniature excitatory postsynaptic currents (mEPSCs) upon application of NE but not 5-HT. …”
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Novel Nanozyme-Based Multicomponent in situ Hydrogels with Antibacterial, Hypoxia-Relieving and Proliferative Properties for Promoting Gastrostomy Tube Tract Maturation by Xiao F, Yan B, Yuan T, He Y, Zhang X, He X, Peng W, Xu Y, Cao J

“…The antibacterial efficiency of the MO-HPA1.0 group on E. coli and S. aureus increased by about 40.1% and 55.6% respectively, compared to the MO-HPA0.5 group. …”
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Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway by Xiao Li, Mengna Cui, Long Xu, Qie Guo

“…ObjectiveSorafenib, a multikinase inhibitor, is currently the standard treatment for advanced liver cancer. …”
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Vertical distribution of ¹³⁷Cs in soddy-podzolic sandy soil in grasslands and forests of the Bryansk region in 2015–2016 by V. P. Ramzaev, A. N. Barkovsky, K V. Varfolomeeva

“…In the meadows in three cases, the maximum activity concentration was determined in the uppermost layer. With increasing depth, the activity concentration decreased and reached a minimum in the deepest layers. …”
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Neutralizing Antibody Spectrum in COVID-19 Patients who Became Ill During the Circulation of Different SARS-CoV-2 Variants by S. K. Pylaeva, L. I. Kozlovskaya, A. A. Erovichenkov, D. I. Sirazova, E. Y. Shustova, E. A. Artamonova, A. A. Sinyugina, I. V. Gordeychuk, D. V. Troshyanskiy, E. V. Kosareva, O. N. Solodovnikova, R. K. Kogotyzhev, A. U. Berestovskaia, I. N. Tyurin, D. N. Protsenko, A. A. Ishmukhametov

“…As the virus circulates, the proportion of re-infected individuals increases, but it is unclear how well neutralizing antibodies formed by infection with early variants neutralize the new Omicron variant lines. …”
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Assessment of the phenolic profile and biological activities of aqueous date seed extracts: A comparative analysis by Tareq M. Osaili, Aseel Swaidan, Anas Al-Nabulsi, Amin Olaimat, Susanne Neugart, Layla Engelhardt, Tuba Esatbeyoglu, Mutamed Ayyash, Leila Cheikh Ismail, Maher M Al-Dabbas, Reyad S. Obaid, Nada El Darra

“…Date palm fruit (Phoenix dactylifera L.) is a well-known fruit that has become increasingly popular among consumers due to its pleasant flavor, nutrient-dense content, and nutraceutical characteristics. …”
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