Ginkgo ketone ester tablets for the treatment of cognitive impairment associated with chemotherapy for breast cancer - a prospective cohort study by Jiajing Chen, Lixin Chen, Kexin Jiang, Dandan Wang, Chunyu Wu, Yuenong Qin, Sheng Liu

“…Biochemical analysis revealed substantial GSH elevation (56% increase) and ROS reduction (41% decrease) at week 24, while TNF-α remained unchanged. …”
Get full text

Biostimulation through natural biological inputs on fruiting, nutrient availability and rhizosphere microbiome in legume intercropped ‘Sweet Charlie’ strawberry (Fragaria × Ananass... by Pramod Kumar, Rajeshwar Singh Chandel, Subhash Chander Verma, Nisha Sharma, Simran Saini, Rohit Bishist, Suman Lata

“…The study further recognised as a practical and affordable solution to farmers in order to improve soil health, increase crop nutrition and lower production costs. …”
Get full text

Surveillance of Unregulated Caffeine Health Claims on Coffee and Other Foods—A Market Analysis by Katharina Höfflin, Veronika Kurz, Yvonne Köder, Kristina Schmied, Verena Bock, Ann-Kathrin Kull, Dirk W. Lachenmeier

“…Due to its stimulating effect on the central nervous system and the associated increase in alertness and reduction in tiredness, caffeine is specifically added to some foods, such as food supplements. …”
Get full text

Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review by A. N. Kulikov, M. V. Zakharov, A. A. Volozhev

“…The main treatment for wet AMD is the injection of medications called anti-VEGF agents. Currently, treatment of dry age-related macular degeneration includes modification of risk factors (stop smoking, healthy life style and etc) and dietary supplements containing a combination of certain ingredients (vitamin C, vitamin E, zinc, copper, and lutein with zeaxanthin or beta-carotene) may be able to slow the progression of the disease. …”
Get full text

Advancing Climate-Resilient Sorghum: the Synergistic Role of Plant Biotechnology and Microbial Interactions by Atul Kumar Srivastava, Aamir Riaz, Junmei Jiang, Xiangyang Li, Mohammad Uzair, Pooja Mishra, Aqib Zeb, Jiwei Zhang, Raghvendra Pratap Singh, Lingfeng Luo, Songshu Chen, Sanwei Yang, Yudan Zhao, Xin Xie

“…Combinations of endophytes and microbial inoculants enhance plant immunity to pests and diseases while increasing tolerance to stress. Biocontrol agents such as Bacillus and Trichoderma contain suppression of pathogens and need less dependence on the use of chemical pesticides. …”
Get full text

Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering by Frederico Barbosa, Fábio F. F. Garrudo, Paola S. Alberte, Leonor Resina, Marta S. Carvalho, Akhil Jain, Ana C. Marques, Francesc Estrany, Frankie J. Rawson, Carlos Aléman, Frederico Castelo Ferreira, João C. Silva

“…The biological cues provided by the HAp nanoparticles enhanced the osteogenic differentiation of seeded human mesenchymal stem/stromal cells (MSCs) as observed by the increased ALP activity, cell-secreted calcium deposition and osteogenic gene expression levels observed for the HAp-containing fibers. …”
Get full text

Silicon-Quantum-Dot Light-Emitting Diodes With Interlayer-Enhanced Hole Transport by Wei Gu, Xiangkai Liu, Xiaodong Pi, Xingliang Dai, Shuangyi Zhao, Li Yao, Dongsheng Li, Yizheng Jin, Mingsheng Xu, Deren Yang, Guogang Qin

“…The highest EQE of ∼2.4% obtained in the current work is among the best values that have been reported for Si-QD LEDs. …”
Get full text

Health and economic evaluation of cytomegalovirus vaccination strategy among young women in China: a modelling study by Bin Zhang, Gang Qin, Jun-Tao Shu, You-Jia Wu, Yin-Hua Jiang, Yi-Wen Ge, Meng-Zhao Yin

“…Background Congenital cytomegalovirus (cCMV) infection imposes a substantial economic burden on both families and society in China. There is currently a paucity of dynamic models to study cytomegalovirus (CMV) vaccination strategies for China’s high-seroprevalence population (over 95%). …”
Get full text

Determining the Teachers' Attitude towards "Mistake" and "Making Mistakes" in the Learning Process and Improving the Culture facing it (case study: elementary school students) by Mazhar Babaee, Hedyeh Azagh

“…With these perceptions, teachers may react differently to students' mistakes. In this context, the teacher's attitude, his awareness and experience of the impact of mistakes on progress and success in dealing with students' mistakes are very important. …”
Get full text

Enhanced Broad-Spectrum Efficacy of an L2-Based mRNA Vaccine Targeting HPV Types 6, 11, 16, 18, with Cross-Protection Against Multiple Additional High-Risk Types by Kosuke Tsukamoto, Akio Yamashita, Masatoshi Maeki, Manabu Tokeshi, Hirotatsu Imai, Akira Fukao, Toshinobu Fujiwara, Koji Okudera, Nobuhisa Mizuki, Kenji Okuda, Masaru Shimada

“…Results: We identified that a construct containing E01 (a 5′-untranslated region) and SL2.7 (a poly(A) polymerase recruitment sequence) significantly increased protein expression. …”
Get full text

The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

“…Bioinformatics analysis showed Cti6 is conservative in Aspergillus spp., and mCherry mediated subcellular localization showed that most Cti6 accumulated in the nuclei, which reflected that Cti6 performed its important biological function in the nuclei in Aspergillus spp.. The results of the current study elucidate the roles of PHD domain containing proteins in the mechanism of the infection of crops by A. flavus, and provided a novel target for effectively controlling the contamination of Aspergillus spp. to crops.…”
Get full text

Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer by Linjie Xu, Xiaotian Yu, Haoming Luo, Jili Wang, Wenjie Liang, Jing Zhang, Zunlei Feng, Cheng Lu, Xiuming Zhang

“…Moreover, pixels in each whole-mount slide of PCa are increased by approximately <inline-formula> <tex-math notation="LaTeX">$4\sim 9$ </tex-math></inline-formula> times, therefore containing more information for diagnosis. …”
Get full text

C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation by Tsung-Ta Liu, Cheng-Tsung Liu, I-Hsun Li, Yu-Chieh Chu, Hao-Yuan Hung, Chuang-Hsin Chiu, Ta-Kai Chou, Shiao-Yun Li, Tin-An Wang, Jui-Hu Shih

“…Abstract Background Parkinson’s disease (PD) is an incurable neurological disorder, and current pharmacological therapies primarily address symptoms without halting disease progression. …”
Get full text

Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extracts against TCDD-induced hepatocyte damage in Jian carp (Cyprinus carpio var. Jian) by Du Jinliang, Cao Liping, Jia Rui, Liu Yingjuan, Shen Yujin, Yin Guojun

“…Jian).Jian carp were fed with diet containing 3 doses of GGE (0.1, 0.5 and 1.0 g/kg diet) for 60 days before a single intraperitoneal injection of TCDD (0.6 μg/kg), 72 h after TCDD injection, blood and liver samples were taken for biochemical analysis.The results showed that GGE at 1.0 g/kg diet for 60 days prior to TCDD intoxication significantly reduced the elevated activities of ALT, AST, LDH, AKP and increased the reduced levels of total protein (TP), albumin (Alb) in the serum, markedly inhibited the reduction of the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), total antioxidant capacity (T-AOC), and reduced the malondialdehyde (MDA) formation in liver tissue. …”
Get full text

Sustainable agriculture through nano-priming: Evaluating the role of biogenic manganese oxide nanoparticles in mitigating wastewater-induced stress in wheat (Triticum aestivum) by Aneeza ISHFAQ, Sabir HUSSAIN, Tanvir SHAHZAD, Muhammed SHAHID, Faisal MAHMOOD, Syed Raza HUSSAIN, Irfan HAIDRI, Imran KHAN, Mahmoud F. SELEIMAN, Muhammad Ahsan ASGHAR, Muhammad Fuad ANSHORI

“…Control included seeds without MnO-NP priming. The wastewater contained contaminants such as heavy metals and organic pollutants. …”
Get full text

Anatomy and function of closing muscle complex of the vagina in health and pelvic organ prolapse by G. B. Dikke, A. D. Makatsariya, A. M. Ziganshin, E. A. Shaikhieva, V. O. Bitsadze

“…Altering integrity of the specified muscle complex (rupture, in-labour overstretching) or its structural degradation characterized by loss of tone and contraction force, results in failed closing genital fissure, increased distance between the medial parts of m. levator ani in the lower third of the vagina and the loss of supporting and closing functions of the pelvic floor as well as POP development. …”
Get full text

Evaluating and Enhancing Japanese Large Language Models for Genetic Counseling Support: Comparative Study of Domain Adaptation and the Development of an Expert-Evaluated Dataset by Takuya Fukushima, Masae Manabe, Shuntaro Yada, Shoko Wakamiya, Akiko Yoshida, Yusaku Urakawa, Akiko Maeda, Shigeyuki Kan, Masayo Takahashi, Eiji Aramaki

“… BackgroundAdvances in genetics have underscored a strong association between genetic factors and health outcomes, leading to an increased demand for genetic counseling services. However, a shortage of qualified genetic counselors poses a significant challenge. …”
Get full text

Antiviral Therapeutics Discovery for Enterovirus D68. by Prof Justin Jang H Chu

“…Through western blot and immunofluorescence staining, the LC3-II/LC3-I ratio and number of LC3 puncta-positive cells increased upon EV-D68 infection, indicating autophagy induction in infected cells. …”
Get full text

Improving Egg Quality in Tropical Environments: Assessing the Maize Meal Replacement by Wheat Bran and Soybean Oil in Laying Hen Diets by Mariana Novela, Abilio P. Changule, Igor I. S. Munguambe, Florentina D. Chilala, Leonel A. Joaquim, Eunice J. Chivale, Marcos Mabasso, Ramos J. Tseu, Filomena dos Anjos, Otília H. T. Tomo, Manuel Garcia‐Herreros, Custódio G. Bila

“…ABSTRACT Background The use of wheat bran (WB) in the monogastric animal feed is limited due to its high fibre content and low energy contents. Objectives The current study evaluated the effect of replacing maize meal with WB, in the absence or presence of soybean oil, on egg quality and economic performance indicators. …”
Get full text

SEED DORMANCY BREAKING OF AN ENDANGERED MEDICINAL TREE SPECIES (TAXUS BACCATA L.) USING EMBRYO CULTURE by Mohamed BEKHOUCHE, Abdelkader MORSLI, Majda KHELIFI-SLAOUI, Roukia BENYAMMI, Hayette ZAOUT, Lakhdar KHELIFI

“…Among the nine treatments, the treatments with 0.5 mg/l TDZ and 1 mg/l GA3 showed the highest germination (100%), while the other treatments all increased the germination percentages significantly compared to the control (37.5%). …”
Get full text