Sustainable agriculture through nano-priming: Evaluating the role of biogenic manganese oxide nanoparticles in mitigating wastewater-induced stress in wheat (Triticum aestivum) by Aneeza ISHFAQ, Sabir HUSSAIN, Tanvir SHAHZAD, Muhammed SHAHID, Faisal MAHMOOD, Syed Raza HUSSAIN, Irfan HAIDRI, Imran KHAN, Mahmoud F. SELEIMAN, Muhammad Ahsan ASGHAR, Muhammad Fuad ANSHORI

“…Control included seeds without MnO-NP priming. The wastewater contained contaminants such as heavy metals and organic pollutants. …”
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Finerenone attenuates downregulation of the kidney GLP-1 receptor and glucagon receptor and cardiac GIP receptor in mice with comorbid diabetes by Duc Tin Tran, Emily S. H. Yeung, Lisa Y. Q. Hong, Harmandeep Kaur, Suzanne L. Advani, Youan Liu, Madiha Zahra Syeda, Sri Nagarjun Batchu, Andrew Advani

“…After 26 weeks, mice were fed a high fat diet containing finerenone (100 mg/kg diet) or high fat diet alone for a further 2 weeks. …”
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Effects of dietary myo-inositol on growth performance, hematological parameters, antioxidant capacity, immunity and resistance against Aeromonas hydrophila in red swamp crayfish (P... by Guoliang Ruan, Heng Zhang, Wei Chen, Liu Fang, Jiu Shu, Qian Wang

“…Myo-inositol (MI) as a vitamin-like nutrient has not been investigated in P. clarkii yet, current study was made to investigate the effect of dietary MI on the growth and health of the crayfish, P. clarkii (8.05 ± 0.71 g) fed with diets containing 0 (M0), 800 (M1), 1600 (M2), 2400 (M3), and 3200 (M4) mg/kg of MI for eight weeks. …”
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Combining the RCAS/tv-a retrovirus and CRISPR/Cas9 gene editing systems to generate primary mouse models of diffuse midline glioma by Sophie R. Wu, Julianne Sharpe, Joshua Tolliver, Abigail J. Groth, Reid Chen, María E. Guerra García, Vennesa Valentine, Nerissa T. Williams, Sheeba Jacob, Zachary J. Reitman

“…Genetically engineered mouse models (GEMMs) are critical to studying tumorigenesis and tumor-immune interactions, which may inform new treatment approaches. However, current midline glioma GEMM approaches are limited in their ability to multiplex perturbations and/or target specific cell lineages in the brain for genetic manipulation. …”
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Electronic cigarette use in relation to changes in smoking status and respiratory symptoms by Linnéa Hedman<sup>+<sup>, Gustaf Lyytinen<sup>+<sup>, Helena Backman, Magnus Lundbäck, Caroline Stridsman, Anne Lindberg, Hannu Kankaanranta, Lina Rönnebjerg, Eva Rönmark, Linda Ekerljung

“…A validated postal questionnaire containing identical questions was used in OLIN and WSAS at baseline in 2006–2008 and at follow-up in 2016. …”
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The attenuated African swine fever vaccine HLJ/18-7GD provides protection against emerging prevalent genotype II variants in China by Zilong Wang, Jiwen Zhang, Fang Li, Zhenjiang Zhang, Weiye Chen, Xianfeng Zhang, Encheng Sun, Yuanmao Zhu, Renqiang Liu, Xijun He, Zhigao Bu, Dongming Zhao

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Intelligent beehive monitoring system based on internet of things and colony state analysis by Yiyao Zheng, Xiaoyan Cao, Shaocong Xu, Shihui Guo, Rencai Huang, Yingjiao Li, Yijie Chen, Liulin Yang, Xiaoyu Cao, Zainura Idrus, Hongting Sun

“…Moreover, our counting algorithm also achieved excellent results, with root mean square error (RMSE) of 1.3 ± 0.1, 0.2 ± 0.0, and 1.6 ± 0.1 in counting the number of bees current, entry, and out scene in an episode, respectively. …”
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An animal model study of simplified optical navigation system-assisted percutaneous lumbar transforaminal puncture by B. N. Wenxiu Chai, Yuqing Chen, Li Sheng, Yong Huang

“…The system significantly improves puncture accuracy while markedly decreasing both the number of puncture attempts and fluoroscopy exposures compared to conventional techniques.…”
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Design and Synthesis of Bis-Chalcones as Curcumin Simplified Analogs and Assessment of Their Antiproliferative Activities Against Human Lung Cancer Cells and <i>Trypanosoma cruzi</... by Gabriela Alves de Souza, Lorrane de Souza Chaves, Afonso Santine M. M. Velez, Jorge Lucas F. Lacerda, Paulo Pitasse-Santos, Jayane Clys Conceição dos Santos, Otávio Augusto Chaves, Carlos Serpa, Raphael do Carmo Valente, Leonardo Marques da Fonseca, Marcos André Rodrigues da Costa Santos, Jhenifer Santos dos Reis, Carlos Antônio do Nascimento Santos, Lucia Mendonça-Previato, Jose Osvaldo Previato, Celio Geraldo Freire-de-Lima, Debora Decoté-Ricardo, Leonardo Freire-de-Lima, Marco Edilson Freire de Lima

“…<b>Background: </b>Anticancer therapies represent the primary treatment option for a significant number of cancer patients globally; however, many of these treatments are associated with severe side effects as they target molecular structures present in both cancerous and healthy cells. In a similar context, the treatment of Chagas disease, a neglected tropical illness, is hindered by the high toxicity of the currently available drugs. …”
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Synergistic Effects of Mannan Oligosaccharides and Onion Peels on In Vitro Batch Culture Fermentation of High Concentrate and Forage Diets by Lydia K. Olagunju, Oludotun O. Adelusi, Peter A. Dele, Yasmine Shaw, Rosetta M. Brice, Oluteru E. Orimaye, Jorge A. Villarreal-González, Hye Won Kang, Ahmed E. Kholif, Uchenna Y. Anele

“…The administration of MOS, OP, and MOS:2OP to the HC diet decreased methane production at 24 h of incubation. …”
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Contribution of the TRPM4 Channel to Osteogenic Differentiation of Human Aortic Valve Interstitial Cells by Margaux Aize, Arthur Boilève, Benoit D. Roussel, Laura Brard, Harlyne Mpweme Bangando, Corentin Kerevel, Alexandre Lebrun, Hind Messaoudi, Vladimir Saplacan, Alain Manrique, Romain Guinamard, Christophe Simard

“…Mineralization and osteogenic markers (bone morphogenetic protein 2, runt‐related transcription factor 2) were decreased when pro‐calcifying media contained 9‐phenanthrol or small hairpin RNA–TRPM4. …”
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Bifidobacterium animalis ssp. lactis BX-245-fermented milk alleviates tumor burden in mice with colorectal cancer by Chengcong Yang, Musu Zha, Lu Li, Jiaqi Qiao, Lai-Yu Kwok, Dandan Wang, Yongfu Chen

“…Collectively, our data suggest that administering probiotic fermented milk containing specific functional strains such as BX245 could result in a reduction in tumor burden in CRC mice. …”
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Effects of coix seed polyphenol extract on rumen fermentation, milk production, fatty acid profile, antioxidant activity, and polyphenol content in dairy goats by X.Z. Tian, Y.Q. Xu, J.X. Qin, X. Wang, S.L. Xie, R. Chen, Q. Lu, X. Chen

“…Overall, the appropriate supplemental level of CSE was 1.5 g/kg in dairy goats under the conditions of the current experiment.…”
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STAT2/SLC27A3/PINK1-Mediated Mitophagy Remodeling Lipid Metabolism Contributes to Pazopanib Resistance in Clear Cell Renal Cell Carcinoma by Dingheng Lu, Yuxiao Li, Xinyang Niu, Jiazhu Sun, Weitao Zhan, Yuchen Shi, Kai Yu, Suyuelin Huang, Xiaoyan Liu, Liping Xie, Xueyou Ma, Ben Liu

“…While tyrosine kinase inhibitors (TKIs) are currently the first-line treatments for advanced/metastatic ccRCC, patients often develop resistance after TKI therapy. …”
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The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e... by Biao Peng, Mu-Yun Yan, Yun-Rong Chen, Fei Sun, Xu-Dong Xiang, Da Liu

“…Objective The prognosis for severe asthma is poor, and the current treatment options are limited. The methyl-CpG binding domain protein 2 (MBD2) participates in neutrophil-mediated severe asthma through epigenetic regulation. …”
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Food Application of Orange Seed Powder through Incorporation in Wheat Flour to Boost Vitamin and Mineral Profiles of Formulated Biscuits by Ashiq Hussain, Salah Laaraj, Tusneem Kausar, Aziz Tikent, Hanane Azzouzi, Samina Kauser, Qurat Ul An, Aqsa Iqbal, Saima Akram, Rizwan Nisar, Ayesha Najam, Haya Fatima, Shazia Yaqub, Kaoutar Elfazazi

“…In the current work, orange seed powder replaced wheat flour at 0, 2.5, 5, 7.5, and 10% levels, to observe changes in physicochemical features of developed biscuits. …”
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“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station by Fang WANG, Zhuoqi LI, Haoyi XU, Jiaqi YAN

“…ObjectiveWithin human – environment systems, river basins constitute the earliest geographical units of human activity and currently represent the most critical zones of strained human – environment interactions. …”
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On the added value of sequential deep learning for the upscaling of evapotranspiration by B. Kraft, B. Kraft, B. Kraft, J. A. Nelson, S. Walther, F. Gans, U. Weber, G. Duveiller, M. Reichstein, W. Zhang, M. Rußwurm, D. Tuia, M. Körner, Z. Hamdi, M. Jung

“…In particular, we investigate three questions regarding the performance of the sequential models compared to the non-sequential models in the context of spatial upscaling: (a) whether they lead to more realistic and robust global and regional ET, (b) whether they are able to capture the temporal dynamics of ET better, and (c) how robust they are to the covariate setup and training data subsets.…”
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Improvement of the perovskite photodiodes performance via advanced interface engineering with polymer dielectric by Andrey P. Morozov, Lev O. Luchnikov, Sergey Yu. Yurchuk, Artur R. Ishteev, Pavel A. Gostishchev, Sergey I. Didenko, Nikita S. Saratovsky, Dmitry O. Balakirev, Ivan V. Dyadishchev, Andrey A. Romanov, Ekaterina A. Ilicheva, Anton A. Vasilev, Sergey S. Kozlov, Dmitry S. Muratov, Yuriy N. Luponosov, Danila S. Saranin

“…IV curve analysis and 2-diode model calculations showed enhanced shunt properties, a decreased non-ideality factor, and reduced saturation dark current. …”
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Regulatory culture and architectural project by Mario Losasso

“…They are attentive to a quality that does not depend on construction solutions or on techno-typological, morphological or physical-chemical characteristics, but which is linked to a system of needs to be satisfied, the outcome of the interaction between construction and cultural, socio-economic and environmental context. Today’s regulatory landscape has expanded, increasing sensitivities to environmental challenges, health and the qualities of living space. …”
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