Unraveling the complex role of microglia in Alzheimer’s disease: amyloid β metabolism and plaque formation by Sho Takatori, Mayuna Kondo, Taisuke Tomita

“…Conversely, we explore findings that challenge this view, such as microglial depletion experiments resulting in unchanged or decreased Aβ accumulation. We propose that the contribution of microglia to Aβ metabolism is context-dependent, varying with disease progression, genetic background, and experimental conditions. …”
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CIS Countries Foreign Economic Activity — from Challenges to New Opportunities by M. S. Goncharov

“…Aim and tasks. To identify current trends and issues in foreign trade, the international financial system, and the investment activity of CIS member states, and to provide recommendations that contribute to sustainable economic development and strengthened mutual cooperation.Methods. …”
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Unlocking the hidden forces: deformation and associated stress distribution in the present-day Geneva Basin and Jura fold-and-thrust belt by Sandra Borderie, Jon Mosar, Adeline Marro, Louis Hauvette

“…If current seismicity indicates that the Geneva Basin is tectonically active, few data regarding the state of stress in the area are currently available. …”
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Social Skills Training Program and its Effect on Quality of Life and Stigma among Patients with Schizophrenia by Samah Ali, Amal Awad, Hanaa Ewise, Shimaa Adam

“… Context: Schizophrenia is a severe mental disorder that significantly disrupts an individual's social interactions, work performance, and overall quality of life. …”
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Therapeutic potential of microRNAs in neurological disorders: mechanisms, biomarkers, and emerging therapeutic strategies by Sourav Pal, Subhajit Mandal

“…We also explore the future of miRNA research in the context of precision medicine, highlighting the importance of targeted delivery, safety optimization, and integration of patient-specific molecular profiles. …”
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Assessing the Spatial Dependence of the Shipped Products Volume in Dynamics by V. M. Timiryanova

“…At the same time, it is obvious that any current state is a consequence of the position achieved by the considered territory in the past. …”
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Business model innovation and SMEs’ resilience: technological roadmap in Nigeria by Oluwakemi R. Alake, Omotayo Adegbuyi, Abiola A. Babajide, Odunayo P. Salau, Oluwakemi O. Onayemi, Opeyemi O. Joel, Oluwatoyin D. Adesanya

“…In summary, this study offers a current road map for technical development in the context of novel business models and the resilience of SMEs in Nigeria. …”
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EXTREME WINTERS IN XX–XXI CENTURIES AS INDICATORS OF SNOWINESS AND AVALANCHE HAZARD IN THE PAST AND EXPECTED CLIMATE CHANGE CONDITIONS by A. D. Oleynikov, N. A. Volodicheva

“…Currently, due to the global climate change and increasing frequency of weather events focus is on prediction of climate extremes. …”
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Semantic Features-Based Discourse Analysis Using Deceptive and Real Text Reviews by Husam M. Alawadh, Amerah Alabrah, Talha Meraj, Hafiz Tayyab Rauf

“…It uses a dataset of real hotel reviews, containing both positive and negative reviews. Under investigation is the hypothesis that strong, fact-based, realistic words are used in truthful reviews, whereas deceptive reviews lack coherent, structural context. …”
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Variation and prognostic potential of the gut antibiotic resistome in the FINRISK 2002 cohort by Katariina Pärnänen, Matti O. Ruuskanen, Guilhem Sommeria-Klein, Ville Laitinen, Pyry Kantanen, Guillaume Méric, Camila Gazolla Volpiano, Michael Inouye, Rob Knight, Veikko Salomaa, Aki S. Havulinna, Teemu Niiranen, Leo Lahti

“…These findings highlight risks and socio-demographic dimensions of antibiotic resistance that are particularly relevant in the current context of global urbanization and middle-class growth.…”
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Strategic Role of the Pharmaceutical Industry in the Сontext of the Global Pandemic by Z. A. Mamedyarov

“…The paper traces the current trends in the growth of innovative competition in pharmaceuticals and biotechnology, taking into account the factor of the COVID-19 pandemic. …”
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After the Astana declaration: is comprehensive primary health care set for success this time? by Per Kallestrup, Christian Kraef

“…In this analysis we (1) examine the challenges that comprehensive PHC faced after the Alma-Ata declaration, (2) provide an analysis of the current opportunities and threats to comprehensive PHC strengthening on the global, national and community level and (3) review the most important policy recommendations and related evidence to address these threats for success of the Astana declaration.Factors that are predominantly opportunities are the treasure of historical lessons from the past 40 years, the increased attention to social and environmental determinants of health, the global economic growth and new technologies, in particular digital medicine, which also have the potential to revolutionise community involvement.Factors that are currently predominantly threats are insecurity, conflicts and disease outbreaks; lack of sustained political commitment and inappropriate monitoring and evaluation structures; inappropriate and unsustainable financing models; insufficient health workforce recruitment, employment and retention; missing support of physicians and their professional organisations; inadequately addressing the needs of the community and not giving attention to gender equity. …”
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Re-establishment and Regarding Trust and Transparency, Blockchain’s Contribution to the Solution of a Thousand-Year Problem by Nataliia Krasnokutska, Koray Adıgüzel

“…It is understood that after the development of technologies that eliminate centralised structures such as Blockchain, the business world is keen to adapt to this change. In this context, it is concluded that including new technologies such as Blockchain increased trust in various industries, and in the majority of the studies, Blockhain considered being an element to reduce costs and create a more transparent environment. …”
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CHAC1 in urological tumors: contextual dualism and therapeutic implications by Deyu Wang, Yongquan Wan, Yunxiang Li, Yuan Ren, Jiakai Ma, Si Ge, Ziqiang Zeng, Zuoping Wang, Lei Zhen

“…CHAC1, a glutathione-degrading enzyme, governs context-dependent pathophysiological processes in urological malignancies through modulation of endoplasmic reticulum stress and ferroptotic pathways. …”
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Intellektuális akadálymentesítés az oktatásban: problémafelvetés, alternatívák keresése by Mónika KRASZNAY

“…Based on the author’s educational and teaching experiences, including a recommended literature, and taking into account the relevant context of the postmodern society (rapidly changing world, rapidly developing sciences, increased amount of but easily/quickly accessible information, communication tools for information dis-semination, etc.), the study considers – and encourages the reader to do the same – the following in terms of both secondary and higher education: ● How and to what extent can we supplement the one-sided memorization of facts and data, the acquisition of lexical knowledge with the technical possibilities of researching and storing information? …”
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Competitiveness of Bulgarian oilseed production in the world market by Bozidar Ivanov

“…In general terms, competitiveness can be comprehended in a static aspect as an outcome on one hand or either as conditions and factors (dynamics) determining that outcome or competitive performance. In the current study, the competitiveness is defined as the capability of the agricultural industries and the production of oilseed crops in Bulgaria to sustain and expand their market share and to maintain and increase the added value of their production in terms of national and global scene. …”
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Analysis of government subsidy strategies in the supply chain of science and technology innovation platform. by Guangsi Zhang, Chen Chen, Jiaping Xie, Qiang Hu

“…To accelerate the realization of S&T innovation, the government provides subsidies to guide the S&T innovation platform and increase the participation of innovation subjects. …”
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Utilizing pistachio green hull extract to produce sugar-free muffins with antioxidant and antidiabetic potential by Amin Karimi, Amir pouya Ghandehari Yazdi, Mohsen Barzegar, Mohammad Rahmati, Nooshin Bazsefidpar, Arash Soltani, Seid Mahdi Jafari

“…The current study aimed to produce sugar-free muffins containing pistachio green hull extract (PGHE) as a natural source of antioxidant and antidiabetic compounds. …”
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Expert Consensus on Clinical Application of Lower Limb Rehabilitation Robots by ZHANG Lixin, BAI Dingqun, BAI Yulong, CHEN Wenhua, CHEN Yan, DU Qing, FAN Maohua, HE Hongchen, HUANG Liping, JIA Jie, LI Jianhua, LI Lei, PAN Yu, SU Min, WANG Hongtu, YIN Yong, ZHANG Bi

“…In addition, referencing the latest research, this consensus elaborates on the working principles, classification, clinical application (indications and contraindications, working parameters and operating procedures, safety), and recommendations on clinical application (hemiplegia, paraplegia, musculoskeletal diseases, childhood diseases and other systemic diseases) when using lower limb rehabilitation robots in the current context. Lower limb rehabilitation robots are well-suitable for patients with walking difficulties and long-term bedridden condition. …”
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Taxpayer protection standard in international tax disputes by M. D. Polenchuk

“…This is especially important for those states that do not use arbitration, such as Russia.The main conclusion is that the application of the standard of protection of human right to a fair trial in relation to the taxpayers in the tax treaty disputes resolution procedures is an efficient way to develop the current mutual agreement procedure and arbitration and to increase the confidence of taxpayers in these mechanisms.…”
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