Repurposing Cyclic Guanosine Monophosphate Pathway Medications, from Vasodilation toward Changing the Face of Heart Failure by Antoine Fakhry AbdelMassih, Buthaina Ramadan, Jana Tarek ElDemerdash, Monia Mostafa Zayed, M. Wasim Soued, Nadine El-Husseiny, Yousef M. Husseiny, Passant Saad

“…Among the most commonly used medications used in this context, is milrinone, which increases the myocardial relaxation velocity, what is known as lusitropy. …”
Get full text

Selection of Prosthesis in Aortic Valve Surgery: Short Review and Trend in our Practice in 10 Years by Selman Dumani, Ermal Likaj, Laureta Dibra, Devis Pellumbi, Adelina Musliu, Fjoralba Qejvani, Altin Veshti

“…In recent decades, due to lifestyle changes, increased average lifespan, and a shift in surgical treatment concepts among the elderly, there has been a noticeable trend towards atherosclerotic aortic valve disease treated surgically. …”
Get full text

A review of the landscape of agroecology policies towards transforming food systems in Sub-Saharan Africa by Kevin Okoth Ouko, Cherine Lando Yugi, Modock Odiwuor Oketch, Jimmy Brian Mboya, Robert John Ogola, Mavindu Muthoka, Dick Chune Midamba

“…Sustainability serves as a normative principle in the context of food policy but also represents a hotly debated arena. …”
Get full text

Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol by Nada Aly H., Zaghloul Abdelazim A., Hedaya Mohsen M., Khattab Ibrahim S.

Get full text

Mapping the Dream: Designing Optimal E-Bike Routes in Valparaíso, Chile, Using a Multicriteria Analysis and an Experimental Study by Vicente Aprigliano, Catalina Toro, Gonzalo Rojas, Iván Bastías, Marcus Cardoso, Tálita Santos, Marcelino Aurélio Vieira da Silva, Emilio Bustos, Ualison Rébula de Oliveira, Sebastian Seriani

“…These findings challenge the current regulatory limit of 250 W for non-motorized vehicles in Chile, highlighting the potential benefits of increasing their power limits to enhance sustainable mobility in the hilly urban contexts of this country. …”
Get full text

Challenges in lentiviral vector production: retro-transduction of producer cell lines by Maximilian Klimpel, Christin Obert, Monica Terrao, Parameswari Singh, Haiyan Wei, Chao-Guang Chen, Andreas Gille, Silke Wissing, Holger Laux

“…The increasing demand for lentiviral vectors (LVs) has led to the development of several stable cell lines and production methods over the last 2 decades in order to increase titers and yields, reduce production costs and improve the safety of the vector product. …”
Get full text

Comparison of Biodynamic and Organic Agriculture by Özlem Çakır, Hilal Yıldız, Neva Karataş

“…By the help of industrial devolution in 18TH century, the increasing popularity and global warming caused the people to notice the ecologic deformation on the earth and accordingly saving the ecology and the earth became one of the main topics of current issues. …”
Get full text

Outcomes of COVID-19 on Patients with Cancer: A Scoping Review by Amjad Alrehaili, Samah Sofar, Duha Wazqar

“… Context: The COVID-19 pandemic has resulted in an unprecedented global health crisis. …”
Get full text

COVID-19 and Inflammatory Bowel Diseases: Risk Assessment, Shared Molecular Pathways, and Therapeutic Challenges by Iolanda Valentina Popa, Mircea Diculescu, Cătălina Mihai, Cristina Cijevschi-Prelipcean, Alexandru Burlacu

“…Conclusions. Using the current understanding of SARS-CoV-2 as well as other pathogenic coronaviruses immunopathology, we showed why IBD patients should not be considered at an increased risk of infection or more severe outcomes. …”
Get full text

Fishing, offshore wind energy, climate change and marine spatial planning: Is it possible to plan for a best use of space? by Neda Trifonova, Beth E. Scott, Stephen C. L. Watson, Claire Szostek, Morgane Declerck, Nicola Beaumont

“…This perspective provides a methodology roadmap that considers the link between, and the need for, both food and energy security from our oceans and provides a route to increased certainty in our current choices for the long‐term sustainable use of our oceans.…”
Get full text

The Silent Burden of De Novo Metastatic Prostate Cancer in the Middle East: A Call for Region-Specific Screening Guidelines by Noura Abbas, Laudy Chehade, Zahi Abdul Sater, Ali Shamseddine

“…<b>Methods</b>: We conducted a comprehensive narrative review of epidemiological data on prostate cancer in the ME, examining trends in incidence and mortality, de novo metastatic cases, and current screening practices. Additionally, we assessed the applicability of international guidelines for prostate cancer screening to the ME context. …”
Get full text

Flavor Quality of Scomberomorus niphonius by Shanyu WANG, Chong JIAN, Yong XUE, Ling ZHAO, Huihui SUN, Rong CAO

“…The signal intensity of valeraldehyde, isovaleraldehyde, butyraldehyde, 3-hydroxy-butanone, and ethyl propionate significantly increased after the fish underwent various sterilization conditions. …”
Get full text

Saccharomyces boulardii supplementation does not affect anaerobic power gain induced by short-term sprint interval training in physically active individuals by A.S.R. Hudson, A.M.T. Lisboa, P.V.R. Andrade, R.S. Bruzzi, Y.A.T. Martins, D.D. Soares, F.S. Martins, S.P. Wanner

“…In conclusion, short-term SIT improved the participants' anaerobic performance (power), as evidenced by increased PPO. Sb supplementation did not affect the improved anaerobic power caused by SIT.…”
Get full text

Rebuilding the Unity of the Muslim Umma: Strategic Pathways in the Wake of the Al-Aqsa Storm Operation (Ṭūfān al-Aqṣā) by Mohamad Rafia

“…Originality: The originality of this work lies in harnessing the current geopolitical changes in the context of Al-Aqsa Storm operation to design a comprehensive strategy to uniting the Muslim Ummah. …”
Get full text

USE OF INFORMATION AND SOFTWARE IN THE MANAGEMENT SYSTEM OF INTERNATIONAL ENTERPRISES by Maryna V. Kovbatiuk, Ivanna I. Strilok, Viktoriya V. Shklyar, George O. Kovbatiuk

“…Therefore, the article explores the importance of this integration in the context of globalized markets, emphasizing its role in increasing competitiveness, introducing innovations and making operational and strategic decisions. …”
Get full text

Relationship of Individual Athlete External Load, Session Rating of Perceived Exertion, and Athlete Playing Status Across a Collegiate Women’s Basketball Season by Faith S. A. Brown, Jennifer B. Fields, Andrew R. Jagim, Erica L. King, Robert E. Baker, Angela Miller, Margaret T. Jones

“…Across all athletes, IL increased across the season (40.11 AU) and for each 1 unit of change in EL, IL increased by 1.04 AU. …”
Get full text

GC-Faster RCNN: The Object Detection Algorithm for Agricultural Pests Based on Improved Hybrid Attention Mechanism by Bolun Guan, Yaqian Wu, Jingbo Zhu, Juanjuan Kong, Wei Dong

“…Experiments have shown that compared with the original Faster RCNN model, GC-Faster RCNN has improved the average accuracy mAP0.5 on the Insect25 dataset by 4.5 percentage points, and mAP0.75 by 20.4 percentage points, mAP0.5:0.95 increased by 20.8 percentage points, and the recall rate increased by 16.6 percentage points. …”
Get full text

A Rotated Object Detection Model With Feature Redundancy Optimization for Coronary Athero-Sclerotic Plaque Detection by Xue Hao, Haza Nuzly Abdull Hamed, Qichen Su, Xin Dai, Linqiang Deng

“…These redundant features interfere with plaque feature extraction, resulting in decreased performance and increased computational complexity. Current methods for addressing redundant features rely mostly on simple feature selection or reduction methods, overlooking the significance of redundant features in model training. …”
Get full text

A Study on Spatial Accessibility of the Urban Tourism Attraction Emergency Response under the Flood Disaster Scenario by Yong Shi, Jiahong Wen, Jianchao Xi, Hui Xu, Xinmeng Shan, Qian Yao

“…With the ultrahigh-speed, large-scale development of tourism and the increasing frequency, intensity, and scope of extreme natural hazards in the context of climate warming, tourism has entered a high-risk era. …”
Get full text

Studio sui NEETs. Credenze, paure e percezioni delle giovani generazioni stigmatizzate by Marco Schiavetta

“…Psychosociological area: to investigate the context and environment of NEETs’ life. The answers to this question must allow them to understand what they are, first and foremost: a) the causes to which they attribute their current NEET situation (external/internal); b) the roads they would like to take to move towards work (Self orientation); c) their thoughts and attitudes towards current social policies (active/passive). 3. …”
Get full text