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Factors associated with variation in single-dose albendazole pharmacokinetics: A systematic review and modelling analysis.
Published 2022-10-01“…This variation might have implications for the efficacy of albendazole treatment, but current understanding of the factors associated with this variation remains incomplete.…”
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1242
Enhancing Unmanned Aerial Vehicle Object Detection via Tensor Decompositions and Positive–Negative Momentum Optimizers
Published 2025-03-01“…The current development of machine learning has advanced many fields in applied sciences and industry, including remote sensing. …”
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1243
Investigation of machining performance of waspaloy using copper-graphite composite electrodes in electric discharge machining
Published 2024-01-01“…In this work, pure copper electrode and three composite electrodes with varying graphite percentages in copper, viz. copper containing 5%, 10%, and 15% graphite (CuGr-5, CuGr-10, and CuGr-15), are utilized for experimentation. …”
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1244
Bone marrow mesenchymal stem cell-derived exosomes alleviate DSS-induced inflammatory bowel disease in mice through inhibiting intestinal epithelial cell pyroptosis via delivery of...
Published 2025-06-01“…BackgroundInflammatory bowel disease (IBD), characterized by chronic intestinal inflammation and epithelial barrier dysfunction, remains a therapeutic challenge due to the limitations of current treatments, including drug resistance and invasive surgical risks. …”
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1245
Optimizing in vitro slow-growth conservation media for garlic under ambient conditions: further implications for core set accessions
Published 2025-08-01“…Therefore, maintaining the crop’s genetic diversity in a suitable alternative form is crucial. The current study standardized the protocol for slow-growth conservation of garlic (in vitro) at an ambient temperature. …”
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1246
Finerenone attenuates downregulation of the kidney GLP-1 receptor and glucagon receptor and cardiac GIP receptor in mice with comorbid diabetes
Published 2024-11-01“…After 26 weeks, mice were fed a high fat diet containing finerenone (100 mg/kg diet) or high fat diet alone for a further 2 weeks. …”
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1247
Experimental study on tensile performance of horizontal joint bolted connections in fully assembled modular construction reinforced concrete
Published 2025-01-01“…According to the calculation theory for punching shear failure bearing capacity, the reduced peak load-bearing capacity of Mode III compared to Mode II was attributed to the reduction in the effective height of the punching shear cone caused by the crushing zone, consequently resulting in decreased anti-punching shear capacity. In Mode IV, when the load was increased to 134.2 kN, abrupt fracture failure of the concrete at the cross-section above the operating hand-hole of the specimen was observed, with limited cracking. …”
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1248
Cranberry Leaves as Feed Additive in Poultry Nutrition: Effects on Performance and Oxidative Stability
Published 2024-05-01“…The leaves belonging to that species can be considered a cost-effective alternative in the context of reducing antibiotics strategy in animal nutrition. …”
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1249
Beyond the brain: early autonomic dysfunction in Alzheimer’s disease
Published 2025-06-01“…These changes were accompanied by diminished sodium (INa), calcium (ICa), and nicotinic (IACh) currents, compromising CC excitability. With age, a shift toward increased potassium (IK) currents and enhanced catecholamine secretion may reflect compensatory adaptations aimed at preserving output. …”
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1250
What type of leadership is more effective for managing change during force majeure? Achieving organizational effectiveness during the pandemic
Published 2023-11-01“…Hence, it was important to identify effective leadership styles to successfully manage the transformational process during the period. Therefore, the current study aims to explore and compare the effectiveness of transformational and ethical leadership (EL) in terms of achieving organizational goals during COVID-19 in public and private sector organizations in Pakistan. …”
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1251
Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa...
Published 2025-03-01“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
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1252
THE IMPACT OF THE USE OF BIOFUELS ON CO2 EMISSIONS AT THE LEVEL OF EUROPEAN COUNTRIES FROM THE PERSPECTIVE OF ABSOLUTE DECOUPLING
Published 2025-01-01“…Decoupling economic growth from CO2 emissions completely is still a key goal of sustainability programs. According to the current research, nations with faster energy transitions and advanced technologies typically see a sharper decoupling, meaning that real GDP growth is attained without a rise in greenhouse gas emissions. …”
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1253
Adverse birth outcome research case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review
Published 2024-12-01“…Abstract Background Adverse birth outcomes (preterm birth, low birth weight, small for gestational age, and stillbirth) seem to persist in infants born to people with HIV, even in the context of maternal antiretroviral therapy. However, findings have been disparate, inconclusive, and difficult to compare directly across settings, partly owing to variable outcome definitions. …”
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1254
Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing
Published 2025-01-01“…Preemptive personalized treatment aimed at preventing these events is a crucial objective of patient management; however, the currently available scoring systems provide only moderate guidance. …”
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1255
Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway
Published 2024-10-01“…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …”
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1256
Adverse kidney related events following targeted therapies in lung cancer: a systematic review and network meta-analysis of randomized controlled trials
Published 2025-03-01“…Targeted therapies did not increase the risk of AKI, yet were associated with higher incidence of proteinuria, particularly vascular endothelial growth factor inhibitors containing therapies. …”
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1257
Electronic cigarette use in relation to changes in smoking status and respiratory symptoms
Published 2024-01-01“…Those who were persistent smokers reported increasing respiratory symptoms. In contrast, the symptoms decreased among those who quit tobacco smoking, but there was no significant difference in respiratory symptoms between quitters with and without e-cigarette use. …”
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1258
Evaluation of the Wind-Resistant Performance of Long-Span Cable-Stayed Bridge Using the Monitoring Correlation between the Static Cross Wind and Its Displacement Response
Published 2018-01-01“…However, few studies currently focus on assessing the wind-resistant performance of existing long-span cable-stayed bridge structures, and at present, no studies have revealed how to identify the deterioration of the wind-resistant performance using a bridge health-monitoring technique. …”
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1259
Temporal and Spatial Evolution and Driving Force Analysis of Water Conservation Function in Yunnan Province Based on Climate and Land Use Change
Published 2024-10-01“…The framework can predict land use change and assess water conservation in the context of future climate change and different economic developments. …”
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Optimization of Distillation Conditions for Improved Recovery of Phthalides from Celery (Apium graveolens L.) Seeds
Published 2021-06-01“…The change of distillation mode from HD to SDE significantly increased the oil yield of whole seeds (from 2.8 to 5.8% for 6 h processing) while maintaining its high phthalide content (62.5%), which translated to an increase in the total phthalide yield from 19.4 to 36.0 g/kg.…”
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