iPSC models of mitochondrial diseases by Sonja Heiduschka, Alessandro Prigione

“…Consequently, most mitochondrial diseases are currently untreatable. Human induced pluripotent stem cells (iPSCs) represent a promising approach for developing human model systems and assessing therapeutic avenues in a patient- and tissue-specific context. iPSCs are being increasingly used to investigate mitochondrial diseases, either for dissecting mutation-specific defects within two-dimensional (2D) or three-dimensional (3D) progenies or for unveiling the impact of potential treatment options. …”
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Enhancing digital literacy in primary education through augmented reality by Natalie Nevrelova, Lilla Korenova, Zsolt Lavicza, Nikola Bruzkova, Angelika Schmid

“…Currently, there is a need to develop digital competencies already because they are included in the new curriculum. …”
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The challenges of reproducibility for research based on geodata web services by M. Cannata, M. Collombin, O. Ertz, G. Giuliani, J. Ingensand, C. Primerano, D. Strigaro

“…Additionally, we assess the currently available tools that support data versioning for databases, files and log-structured tables. …”
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Two-Hour Sea Level Oscillations in Halifax Harbour by Dan Kelley, Clark Richards, Ruby Yee, Alex Hay, Knut Klingbeil, Phillip MacAulay, Ruth Musgrave

“…We explore the nature of the oscillations as a first step towards the improvement of prediction schemes for sea level and currents in the region. This involves an analysis of the oscillations in the context of seiche and Helmholtz resonance theories and the use of a 2D numerical model to handle realistic bathymetric conditions and other complications that the simpler theories cannot address. …”
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Natural Alternatives in the Treatment of Colorectal Cancer: A Mechanisms Perspective by Karen Vanessa Fernandez-Muñoz, Cuauhtémoc Ángel Sánchez-Barrera, Marco Meraz-Ríos, Jose Luis Reyes, Eloy Andrés Pérez-Yépez, Maria Teresa Ortiz-Melo, Luis I. Terrazas, Monica Graciela Mendoza-Rodriguez

“…Curcumin, trimethylglycine, resveratrol, artemisinin, and some helminth-derived molecules, among others, are some natural compounds studied in the context of CRC. This review discusses the main benefits, mechanisms, advances, and dark side of conventional chemotherapeutics currently evaluated in CRC treatment. …”
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In silico identification of silent primycin biosynthetic gene clusters within the family Pseudonocardiaceae by Márk Kovács-Valasek, Csaba Fekete, Andrea Kovács-Valasek

“…In the global effort to discover or design new effective antibiotics to fight infectious diseases, the increasingly available multi-omics data with novel bioinformatics tools open up new horizons for the exploration of the genetic potential of bacteria to synthesize bioactive secondary metabolites. …”
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THE WEEKEND TOUR AS THE PROSPECTIVE TREND OF RURAL DEVELOPMENT by О. В. Чайковська, О. В. Чайковський

“…The authors of the article are convinced that the study and adopting the best practices of European countries in the context of a weekend tour will contribute to an increase in income from domestic tourism. …”
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Flavonoid intake in European adults (18 to 64 years). by Anna Vogiatzoglou, Angela A Mulligan, Marleen A H Lentjes, Robert N Luben, Jeremy P E Spencer, Hagen Schroeter, Kay-Tee Khaw, Gunter G C Kuhnle

“…For this reason, there is an increasing interest in investigating the potential health effects of these compounds. …”
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Mengkriminalisasi Greenwashing: Menjawab Tantangan Perlindungan Konsumen di Era Keberlanjutan by Zentoni, Budi Santoso, David M. L. Tobing

“…This phenomenon has grown alongside increasing public awareness of the importance of environmental sustainability. …”
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Assessing the impact of cryptocurrency usage on cybersecurity: the European Union experience by S.V., K.O.

“…Therefore, researching the impact of cryptocurrency usage on cybersecurity is currently a relevant issue. The purpose of this study is to investigate the impact of cryptocurrency usage on cybersecurity in European Union countries. …”
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Public Private Partnership in the European Union: Experiences in the UK, Germany and Austria by Ronald W. McQuaid, Walter Scherrer

“…The political context of governments differs between the UK, Germany and Austria, but each government currently has a positive view of Public private Partnership (PPP). …”
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Reporting Together: Transactional Sociability, Digital Communities and Alternate Embodiments on the Road through the Use of Waze by Regner Ramos

“…The paper seeks to fill a gap in digital spatial theory by upholding that apps are made at a fast pace to help increase their commercial value, but their development, design, and research currently lacks critical study. …”
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The evolution and scope of Article 38 of the Convention on the Rights of the Child in a globalizing world by Dawid Stadniczeńko

“…Observational method, document examination method, method of analysis and criticism of literature Results The scope of contemporary research on childhood within the context of international discourse reveals the necessity of revising the approach to children and their issues. …”
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Anticipating how spatial fishing restrictions in EU waters perform to protect marine species, habitats, and dependent fisheries by François Bastardie, Amaia Astarloa, Logan Binch, Isabella Bitetto, Dimitrios Damalas, Jochen Depestele, Pierre-Yves Hernvann, Sigrid Lehuta, Jonas Letschert, Irida Maina, Stéphanie Mahévas, Georgia Papantoniou, Miriam Püts, Giovanni Romagnoni, Giovanni Romagnoni, Giovanni Romagnoni, Giovanni Romagnoni, Maria Teresa Spedicato, Klaas Sys, Irini Tsikopoulou, Gert Van Hoey, Walter Zupa, Anna Rindorf

“…As the proportion of closed regions increases, potential effects on marine ecosystems can even be damaging in the short term to some sensitive species (such as the endangered, threatened and protected species ETP) and vulnerable habitats (with currently high relative benthic status RBS). …”
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Principles of care for adolescent girls with eating disorders and body disturbances disorders: lessons from the COVID-19 pandemic by A. A. Pichikov, Y. V. Popov, Y. A. Yakovleva, T. A. Salomatina

“…The most reasonable approaches during the pandemic are the approaches focused on the family of a teenager using, if possible, remote forms of assistance.Conclusions: Currently, there are no norms and standards in the organization of assistance to adolescents with eating disorders and body image disorders in the pandemic context. …”
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Urban human-elephant conflict in Zimbabwe: a case study of the mitigation endeavour by Aliénor Scrizzi, Sébastien Le Bel, Mike La Grange, Daniel Cornélis, Cheryl Mabika, René Czudek

“… With the expansion of urbanization, urban cases of human-wildlife conflict are increasing worldwide. Africa’s population, currently at 1.3 billion, is expected to reach 4 billion by 21001. …”
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Innovative Thermosensitive Composite Materials: Merging Poloxamer PF‐127 and Polysaccharides for Enhanced Functional Properties by Marcos Blanco‐López, Inmaculada deDios‐Pérez, Álvaro González‐Garcinuño, Antonio Tabernero, Eva Martín del Valle

“…Abstract Currently, new cancer treatment options are being developed following tumor resection surgery, with a focus on minimizing invasiveness and reducing systemic toxicity to lower the risk of recurrence. …”
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Assessing coupled human-flood interactions using LiDAR geostatistics and neighbourhood analyses by Morgan J. Breen, Abiy S. Kebede, Carola S. König

“…The paper integrates well-established methods from other spheres of flood risk assessment in a novel way to explore the currently poorly understood Safe Development Paradox (SDP) phenomenon in coastal settings. …”
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A Methodological Proposal for Determining Environmental Risk Within Territorial Transformation Processes by Marco Locurcio, Felicia Di Liddo, Pierluigi Morano, Francesco Tajani, Laura Tatulli

“…The built assets and the real estate sector play a key role in this context; indeed, being among the first ones to be exposed to the effects of climate change, they serve as a crucial tool for the implementation of governance strategies that are more focused on environmental issues. …”
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Avoiding Error and Finding the Right Balance in European Health Technology Assessments: Insights Generated by the European Access Academy by Elaine Julian, Tom Belleman, Maria João Garcia, Maureen Rutten-van Mölken, Robin Doeswijk, Rosa Giuliani, Bernhard J. Wörmann, Daniel Widmer, Patrick Tilleul, Ruben Casado Arroyo, Valentina Strammiello, Kate Morgan, Marcus Guardian, Michael Ermisch, Renato Bernardini, Fabrizio Gianfrate, Stefano Capri, Carin A. Uyl-de Groot, Mira Pavlovic, Jörg Ruof

“…Results: In the survey, 65.5% of respondents indicated that experts are currently not sufficiently included in the upcoming joint scientific consultations and clinical assessments; only 37.9% suggested that the EU HTA joint procedures would accelerate national appraisal decision-making, and 58.6% believed that the principles of ‘transparency’ and ‘competency’ are balanced in the EU HTA position on conflict of interest. …”
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