Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants... by J. C. vanMaanen, F. C. Bach, J. W. Snuggs, K. Ito, M. H. M. Wauben, C. L. Le Maitre, M. A. Tryfonidou

“…Secretion of IL‐6 and C‐X‐C motif chemokine ligand 1 was significantly decreased in NC‐EV + IL‐1β vs. control+IL‐1β but not compared to EV‐depleted human explant controls. …”
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Residents’ Perceptions of Impending Forced Relocation in Urban China by Xin Li

“…On the other hand, many homeowners and older people are unwilling to move, since their current neighbourhood makes them feel rooted and enables them to develop living strategies to relieve their deprived socio-economic situation. …”
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Helminth Coinfections Modulate Disease Dynamics and Vaccination Success in the Era of Emerging Infectious Diseases by Brice Armel Nembot Fogang, Linda Batsa Debrah, Michael Owusu, George Agyei, Julia Meyer, Jonathan Mawutor Gmanyami, Manuel Ritter, Kathrin Arndts, Derrick Adu Mensah, Tomabu Adjobimey, Achim Hörauf, Alexander Yaw Debrah

“…Helminth infection can also negatively impact vaccine efficacy by suppressing B cell activity, reducing antibody levels, and decreasing vaccine effectiveness against infectious diseases. …”
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Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window by Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani

“…In the cancer immune cycle, the immune checkpoint PD-1 and its ligand PD-L1 collaborate to facilitate immune escape and promote tumor progression (Keir et al., 2008). In this context, a study revealed that lactate can enhance the expression of PD-L1 on tumor cells, suggesting that lactate may have a protective effect against tumors by increasing PD-L1 expression (Feng et al., 2017). …”
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DEVELOPMENT PROSPECTS OF THE RUSSIAN MARKET OF TECHNICAL SERVICING AND REPAIR IN THE СONTEXT OF A PANDEMIC by O. A. Tettsoeva

“…Currently, at a time of decreasing automotive production caused by the suspension of the plants in the period of lockdown, the reduction in purchasing power of communities connected with the risk of unemployment occurrence in consequence of business failures, the decline in wages and lower vacancy rates, is foreseen reduced demand for new cars against the background of significant increase in sales volumes in the used cars market segment and, therefore, sharp increase in demand for car services performing technical servicing and repair. …”
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STAT, SOCIETATE ŞI ISLAM ÎN DANEMARCA DE ASTĂZI by Iancu, Ana-Maria

“…However, this model of the relationship between the state and the Church is currently facing significant challenges due to the growth of religious diversity, particularly the relatively rapid increase in the number of Muslim immigrants.…”
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Faut-il en finir avec la Charte de Venise ? by Claudine Houbart

“…However, many of the issues that currently shape the global heritage landscape are absent from the document, which was drafted in a context very different from our own. …”
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PROBLEM ISSUES IN THE IMPLEMENTATION OF INNOVATIONS AND DIGITAL TECHNOLOGIES IN AGRICULTURAL PRODUCTION IN THE CONDITIONS OF NBIC CONVERGENCE by Marianna VASILCHENKO, Elena DERUNOVA, Anton VORONOV, Maria RGEVSKAYA

“…Currently, in the agro-industrial complex, the problem of import substitution of key technological solutions, innovative resources and digital technologies is becoming increasingly important for increasing agricultural production. …”
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About Our 24th Issue

“…We have determined the themes of our journal for 2024 as Discourse and Reality and Social Memory in order to analyze the sociocultural, political economic, and technological order and system that people are experiencing currently. In this context, we are proud to publish the first issue of the year under the theme of Discourse and Reality. …”
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Modern ideas about the role of the galaninergic system in the pathogenesis of heart failure and myocardial remodeling by A. A. Yafarova, A. R. Kiselev, A. F. Sheptulina, O. M. Drapkina

“…In this regard, the search for new molecules for therapeutic action aimed at preventing myocardial remodeling is of undoubted interest. In this context, the galaninergic system seems to be a promising target. …”
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What do we know about digital public debate? Technological affordances and democratic dilemmas by Gulbrandsen Ib T., Just Sine N.

“…We illustrate the resulting six types of participation through a review of empirical studies based in the Nordic context. We summarise what we currently know about digital public debate in a key democratic dilemma: increasing digital participation goes hand in hand with decreasing institutional trust.…”
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Framing the Open (Urban) Project: Insights from Landscape and Ecology by Jeannette Sordi

“…Currently, the threat posed by climate change and the increasing investment from cities on creating and repurposing open spaces and infrastructure, is feeding a renovated interest in landscape design. …”
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Learning the TEI in a Digital Environment by Stella Dee

“…This article provides a brief overview of currently-available digital resources for learning to understand and use the TEI Guidelines. …”
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Artificial Intelligence and Machine Learning at the Intersection of Privacy and Archives by Iori Khuhro, Erin Gilmore, Jim Suderman, Darra L. Hofman

“… As records are increasingly born digital – and thus, at least ostensibly, potentially much more accessible – archivists find themselves struggling to enable general access while providing appropriate privacy protections for the torrent of records being transferred to their care. …”
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Effectiveness of Physiotherapy and Occupational Therapy after Traumatic Brain Injury in the Intensive Care Unit by Stephanie Hellweg

“…Physiotherapy and occupational therapy are frequently administered in intensive care units (ICUs) after traumatic brain injury (TBI) to promote recovery. The increasing economic pressure and the growing need for evidence of therapeutic effectiveness are reasons for reviewing the currently available scientific data. …”
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Circle of Security - Parenting: A Systematic review on Effectiveness of use of the parent training program within Multi-problem Families by Tina Gerdts-Andresen

“…Introduction: Circle of Security-parenting (COS-p) is a simplified, relationship-based programme with the intention of developing parents’ observation and inferential skills related to understanding their child’s needs, increasing sensitivity to their child, aiding in emotional regulation, as well as decreasing any of their negative attributions to their child. …”
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The water level regime of periglacial lakes during the growth stage (the lakes of the Tavan-Bogdo-Ola mountain massif, South-Eastern Altai) by V. A. Rasputina, G. V. Pryakhina, D. A. Ganyushkin, D. V. Bantcev, N. A. Paniutin

“…Assessment of the dynamics of high-altitude glacial lakes is becoming increasingly important in the context of modern climate instability. …”
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Model of regional human resource management as a tool for sustainable development of the socioeconomic system by Veronika S. Zhukova

“…Integration of regional human resource management into the process of achieving goals of national economy is of particular importance in the context of the need for a comprehensive and systemic approach to the development of territories. …”
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Implementation of the National Project «Labor Productivity and Employment Support» in the Perm Region: Facts, Problems, Prospects by T. V. Alexandrova, V. L. Popov

“…In the context of the reorientation of the Russian economy towards an innovative development path, the issue of increasing labor productivity has become an important part of state policy.Currently, the country is implementing a large-scale national project «Labor productivity and employment support». …”
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Based on the Logistic regression analysis method, the carbon emission indicators of a certain province are analyzed Analysis and research by Hu Zhengxi

“…China is currently in an important period of strategic opportunities, experiencing rapid economic development, gradual social transformation, and increasingly prominent environmental issues.Achieving sustainable development of the economy, society, and environment is currently the most important task. …”
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