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4501
Plant Cell Culture-Derived Saponin Adjuvant Enhances Immune Response Against a Stabilized Human Metapneumovirus Pre-Fusion Vaccine Candidate
Published 2024-12-01“…Results: In mice, TLR4 agonist containing adjuvant formulations with plant cell-produced QS-21 performed equally to licensed adjuvant AS01 containing tree-bark-extracted QS-21 and demonstrated a significant increase in immunogenicity against HMPV preF compared to the unadjuvanted control. …”
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4502
Petrochemical characteristics of ancient weathering crusts with scandium concentrations in the Nakyn kimberlite field
Published 2024-11-01“…Currently, this Formation is considered the most promising for scandium mineralization compared to other areas in the Malo-Botuobinsky and Ygyattinsky diamond-bearing regions of Yakutia with the identified scandium concentrations. …”
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4503
Project-based action in the structure of educational-game environments
Published 2025-06-01“…Currently, the problem of declining motivation among school students in the context of the modern education system, which is heavily focused on preparing for the Unified State Exam (USE) and Olympiads, is widely recognized. …”
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4504
Climate Change and Malaria in Canada: A Systems Approach
Published 2009-01-01“…Competent malaria vectors currently exist in southern Canada, including within this range several major urban centres, and conditions here have historically supported endemic malaria transmission. …”
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4505
Access to Substituted Tricyclic Heteroarenes by an Oxidative Cyclization Reaction and Their Antifungal Performance
Published 2025-02-01“…<b>Background/Objectives</b>: Fungal pathogens are increasingly developing concerning resistance against the currently available antifungal drugs, which creates a constant demand for new antifungal agents. …”
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4506
Academic Mobility in Teacher Education
Published 2020-08-01“…Nowadays, it is hard to consider higher education of the 21st century without the global context. The increasing globalisation opens up many opportunities for higher education development, while becoming a challenge to national systems for the training of qualified professionals, including teachers. …”
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4507
Rehabilitation interventions delivered via telehealth to support self-management of rheumatic and musculoskeletal diseases: A scoping review protocol.
Published 2024-01-01“…Data will be summarized qualitatively, and if appropriate, quantitatively via frequency counts of the components comprising the 'Concept' and 'Context' categories of the PCC framework.<h4>Discussion</h4>Findings from the proposed scoping review will identify how telehealth is currently used in the delivery of rehabilitation interventions for RMDs. …”
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4508
Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease
Published 2024-12-01“…Polycystic ovary syndrome (PCOS) is the predominant endocrine disorder among women of reproductive age and represents the leading cause of anovulatory infertility, which imposes a considerable health and economic burden. Currently, medications used to treat PCOS can lead to certain adverse reactions, such as affecting fertility and increasing the risk of venous thrombosis. …”
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4509
On a novel method to synthesize POSS-based hybrids: An example of the preparation of TPU based system
Published 2013-12-01“…Furthermore, an increase of surface water wettability, evidenced by the decrease of water contact angle from 95° for pristine TPU to 70° in TPU containing 10"wt% of reactive POSS, is found.…”
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4510
Gaps in Hospice and Palliative Care Research: A Scoping Review of the North American Literature
Published 2020-01-01“…To determine what gaps currently exist in hospice and palliative/end-of-life care research within the context of a North American setting to ensure that future directions are grounded in appropriate evidence. …”
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4511
A novel RNN architecture to improve the precision of ship trajectory predictions
Published 2025-12-01“…Currently, the Ornstein-Uhlenbeck (OU) model is considered the state-of-the-art for STP. …”
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4512
HIV-1 Drug Resistance Mutations: Potential Applications for Point-of-Care Genotypic Resistance Testing.
Published 2015-01-01“…The increasing prevalence of acquired and transmitted HIV-1 drug resistance is an obstacle to successful antiretroviral therapy (ART) in the low- and middle-income countries (LMICs) hardest hit by the HIV-1 pandemic. …”
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4513
Hair loss: The role of nutritional support in a comprehensive approach to hair loss treatment
Published 2025-01-01“…There are various causes of hair loss, the main one being nutritional deficiencies, micro-, macronutrients and vitamins (zinc, iron, vitamin D, essential amino acids). Currently, there are no generally accepted clinical guidelines for the treatment of telogen effluvium, which makes it difficult to choose a therapeutic algorithm. …”
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4514
Intermittent pneumatic compression for venous thromboembolism prevention: a systematic review on factors affecting adherence
Published 2020-09-01“…These findings could be used to inform future research and quality improvement efforts to increase adherence in this very important, but currently under-researched area.…”
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4515
THE SCOPE OF GLOBALIZATION AND ITS IMPACT ON THE ECONOMIC AND FINANCIAL-BANKING SECTOR
Published 2011-04-01“…The general term used to characterize this increasing interdependence of the human society is that of globalization.…”
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4516
Advances in CO-SCR Catalysts and Reaction Mechanisms
Published 2025-04-01“…It also analyzes the reaction mechanisms and approaches for mitigating catalyst poisoning under different reaction conditions, such as oxygen-rich, water-containing, sulfur-containing, and various complex environments. …”
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4517
Preparation, characterization and activity verification of xylooligosaccharides from plantain straw
Published 2024-12-01“…Currently, the utilization value of plantain straw is low. …”
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4518
High-performance liquid chromatography–tandem mass spectrometry for simultaneous determination of 23 antidepressants and active metabolites in human serum and its application in th...
Published 2025-03-01“…Currently, the treatment of depression mainly relies on drug intervention. …”
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4519
Application of alternative <i>de novo</i> motif recognition models for analysis of structural heterogeneity of transcription factor binding sites: a case study of FOXA2 binding sit...
Published 2021-03-01“…The combination of these four models allowed a signif icant increase in the fraction of recognized peaks compared to that for the sole PWM model: the increase was 26.3 %. …”
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4520
Changes in Farm Supply Voltage Caused by Switching Operations at a Wind Turbine
Published 2024-11-01“…Renewable electricity sources are now widely used worldwide. Currently, the most common sources are those that use energy contained in biomass, water, sun, and wind. …”
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