Towards the Integration of Additive Manufacturing for Freeform Steel and Glass Façade Construction by Lia Tramontini

“…Therefore, seeing AM as an opportunity to improve on current fabrication strategies, this dissertation aims to answer the following question: How can additive manufacturing be effectively utilized to develop node solutions that support freeform steel and glass façade construction? …”
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Where heat does not come in waves: a framework for understanding and managing chronic heat by Mayra Cruz, Katharine J Mach, Lynée L Turek-Hankins, Kilan C Ashad-Bishop, Zinzi D Bailey, Scotney D Evans, Ashley Fanning, Margo Fernandez-Burgos, Jane Gilbert, Bereatha Howard, Monique Mahabir, Julia Marturano, Lisa N Murphy, Nkosi Muse, Joanne Pérodin, Amy C Clement

“…Research on heat and its risks has focused on heat waves as an increasing emergency under climate change, but this emphasis has obscured the chronic—not just acute and episodic—exposure of billions of people globally to increasingly dangerous levels of heat. …”
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Combined TNF-α and OX40L targeting as a new treatment option for hidradenitis suppurativa by Thomas Leeuw, PhD, Deimantė Šimaitė, PhD, Karen Heyninck, PhD, Clement Levin, PhD, Sigrid Cornelis, PhD, Youssef Hijazi, PhD, Heidi Rommelaere, PhD, Thomas Kreutzberg, PhD, Peter Florian, DVM, Markus Kohlmann, PhD, Theresa-Charlotte Brembach, PhD, Frank Nestle, MD, FmedSci, Kerstin Wolk, PhD, Robert Sabat, MD, PhD, Matthias Herrmann, PhD

“…Conclusion: OX40-OX40L interaction is a key pathogenetic feature in HS, and patients with HS might benefit from combined TNF-α/OX40L blockade by SAR442970, which is currently investigated in a clinical phase 2 trial.…”
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HIV-1 suppression and rare dolutegravir resistance in antiretroviral-experienced people with HIV in Liberia by James Soka Moses, Alice K. Pau, Safia Kuriakose, Greg Grandits, Cavan Reilly, Brad T. Sherman, Weizhong Chang, Lisheng Dai, Muhammad A. Khan, Helene Highbarger, Moses Mannah, Johnathan McCullough, Carla Chorley, Isaac Morlu, Joseph Dorbor, Ophelia Talweh Bongolee, Rebecca Slewion, Esther Akpa, Barthalomew Wilson, April L. Poole, Stacy L. Kopka, Tracey Miller, Cecelia J. Nuta, Christina Lindan, David Glidden, Jeffrey N. Martin, Kumblytee L. Johnson, Robin L. Dewar, Ian Wachekwa, Stephen A. Migueles

“…Abstract Background Increasingly, persons with HIV in Liberia are receiving antiretroviral therapy containing the integrase strand-transfer inhibitor (InSTI) dolutegravir (DTG), but the prevalence of and factors associated with virologic failure and HIV drug resistance (HIVDR) remain unknown. …”
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Against Futility Judgments for Patients with Prolonged Disorders of Consciousness by William Choi

“…The field of disorders of consciousness is pervaded by much uncertainty due to limitations on our current diagnostic tools, treatments, and outcome measures. …”
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EstablishINg the best STEp-up treatments for children with uncontrolled asthma despite INhaled corticosteroids (EINSTEIN): protocol for a systematic review, network meta-analysis a... by Ian Sinha, Dyfrig A Hughes, Michelle Maden, Stephen Turner, Sofia Cividini, Sarah Donegan, Giovanna Culeddu, Katie Rose, Olive Fulton, Catrin Tudur Smith

“…Treatment with a low-dose ICS, however, fails to control asthma symptoms in around 10%–15% of children and this places the individual at increased risk for an asthma attack. At present, there is no clear preferred treatment option for a child whose asthma is not controlled by low-dose ICS and international guidelines currently recommend at least three treatment options. …”
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Is drought protection possible without compromising flood protection? Estimating the potential dual-use benefit of small flood reservoirs in southern Germany by S. Q.-G. Ho, S. Q.-G. Ho, S. Q.-G. Ho, U. Ehret, U. Ehret

“…<p>As climate change drives the intensification and increased frequency of hydrological extremes, the need to balance drought resilience and flood protection becomes critical for proper water resources management. …”
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CREATING THE KULTUK POLYGON FOR EARTHQUAKE PREDICTION: VARIATIONS OF (234U/238U) AND 87SR/86SR IN GROUNDWATER FROM ACTIVE FAULTS AT THE WESTERN SHORE OF LAKE BAIKAL by S. V. Rasskazov, E. P. Chebykin, A. M. Ilyasova, E. N. Vodneva, I. S. Chuvashova, S. A. Bornyakov, A. K. Seminsky, S. V. Snopkov, V. V. Chechel'nitsky, N. A. Gileva

“…Determinations of (234U/238U) in groundwater samples are used for monitoring current deformations in active faults (parentheses denote activity ratio units). …”
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Microvesicles Derived from Human Embryonic Neural Stem Cells Inhibit the Apoptosis of HL-1 Cardiomyocytes by Promoting Autophagy and Regulating AKT and mTOR via Transporting HSP-70 by Lei Zhang, Jianyi Gao, Tianyan Chen, Xiang Chen, Xianyan Ji, Kai Ye, Jiahong Yu, Bin Tang, Yusheng Wei, Hong Xu, Jiabo Hu

“…Additionally, hESC-NSC-derived MVs contained high levels of heat shock protein 70 (HSP-70), which can increase the level of HSP-70 in cells. …”
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Evaluation of parenting interventions for those with additional health and social care needs during pregnancy: THRIVE a multi-arm RCT with embedded economic and process components by Marion Henderson, Anja Wittkowski, Katie Buston, Karen Crawford, Alice MacLachlan, Alex McConnachie, Emma McIntosh, Claudia-Martina Messow, Catherine Nixon, Rosaleen O’Brien, Shona Shinwell, Daniel Wight, Yiqiao Xin, Rachel Calam, Ruth Dundas, James Law, Helen Minnis, Lucy Thompson, Philip Wilson

“…Mellow Bumps in comparison, comprises of seven weekly antenatal sessions and one postnatal session. It aims to decrease maternal stress, increase understanding of neonates’ capacity for social interaction, and emphasise the importance of early interaction for brain development and attachment. …”
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Direct oral penicillin challenge in secondary care with low-risk patients: the SPACE mixed-methods study with cost-effectiveness analysis by Mamidipudi Thirumala Krishna, Yogini H Jani, Iestyn Williams, Ruben Mujica-Mota, Rebecca Bestwick, Michele Siciliano, Robert Michael West, Rashmeet Bhogal, Bee Yean Ng, Kornelija Kildonaviciute, Rachel Pollard, Nicola Jones, Louise Dunsmure, Mairead McErlean, Neil Powell, Chidanand C Hullur, Ariyur Balaji, Jonathan Sandoe, Amena Warner, Ron Daniels, Caroline Thomas, Siraj A Misbah, Louise Savic

“…Penicillin allergy labels lead to increased risk for serious hospital infections and longer hospital stay and are associated with higher estimated healthcare costs. …”
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Whole-blood model reveals granulocytes as key sites of dengue virus propagation, expanding understanding of disease pathogenesis by Hansa Praneechit, Somchai Thiemmeca, Dararat Prayongkul, Kessiri Kongmanas, Dumrong Mairiang, Nuntaya Punyadee, Adisak Songjaeng, Nattaya Tangthawornchaikul, Nasikarn Angkasekwinai, Kanokwan Sriruksa, Yupin Suputtamongkol, Wannee Limpitikul, John P. Atkinson, Panisadee Avirutnan

“…Current models for studying DENV pathogenesis often lack the complexity of the human immune system, hindering the development of effective therapies and vaccines. …”
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Spatio-temporal forecasting of COVID-19 cases in the Netherlands for source and contact tracing by Max Keuken, Jizzo R. Bosdriesz, Anders Boyd, Elisabeth M. den Boogert, Ivo K. Joore, Nicole H.T.M. Dukers – Muijrers, Gini van Rijckevorsel, Hannelore M. Götz, Irene E. Goverse, Mariska W.F. Petrignani, Stijn F.H. Raven, Susan van den Hof, Kirsten V.C. Wevers-de Boer, Maarten F. Schim van der Loeff, Amy Matser

“…Due to the rapid increases in incidence of COVID-19 in the Netherlands, the capacity to conduct a full SCT quickly became insufficient. …”
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A retrospective assessment of COVID-19 vulnerability index indicators and mortality rates pre-COVID-19 (2018–2020) and during COVID-19 (2020–2022) in a health and demographic surve... by Takwanisa Machemedze, Chodziwadziwa Whiteson Kabudula, Jean Juste Harrisson Bashingwa, Beth A. Tippett Barr, Nellie Myburgh, Sana Mahtab, Cleopas Hwinya, Stephen Tollman, Ziyaad Dangor, Shabir A. Madhi

“…Using indicators included in a COVID-19 Vulnerability Index, previously developed in South Africa, the current study established a composite COVID-19 vulnerability index, stratified into tertiles. …”
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Fatores que potencializam a participação e comunicação dos estudantes de ensino superior na modalidade a distância / Factors that enhance the participation and communication of hig... by Paula Santos Orofino, Adson Nogueira Alves, Raphael Sigolo Ruas Gonçalves, Vitor da Silva Palacios, Mônica Cristina Garbin

“…In addition to providing students with a more active participation in this communication process in the context of distance education, considering that the teaching and learning process occur in a mediated, collaborative way and through social interactions in the midst of the knowledge society. …”
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Analysis of Interdisciplinary Differences in the Structure of the Scientific Genre in the Introduction Section of Humanities Research Articles by Roya Peyravi, Hossein Ghorbanpoor Arani, Abbas Zaree

“…The findings of this research are both applicable and feasible for evaluating the current challenges in scientific writing. In this context, two key recommendations have been proposed to improve academic writing in the Persian language. …”
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Addressing Shortcomings in Contingency Standards of Care by Alexander Quan

“…Lack of Formalization One shortcoming of current contingency measures is that they fail to meet the same level of procedural detail and clarity as crisis standards. …”
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Mineralogy and sulfide mineral chemistry of Khabr iron ore, Southwest of Baft (Southeast of Sanandaj-Sirjan Zone) by Mohammad Boomeri, Habib Biabangard, Somayeh Dehghani Soltani, Azadeh Bordbar

“…The chemistry of arsenopyrite, pyrite and chalcopyrite contain low volumes of gold, silver, bismuth, Pb, Zn, Te and mercury. …”
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Mortality impact, risks, and benefits of general population screening for ovarian cancer: the UKCTOCS randomised controlled trial by Usha Menon, Aleksandra Gentry-Maharaj, Matthew Burnell, Andy Ryan, Jatinderpal K Kalsi, Naveena Singh, Anne Dawnay, Lesley Fallowfield, Alistair J McGuire, Stuart Campbell, Steven J Skates, Mahesh Parmar, Ian J Jacobs

“…While screening did not increase anxiety, there was slightly increased worry in women who were asked to return for more intense repeat testing. …”
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Role of NLRP3 Inflammasome in Heart Failure Patients Undergoing Cardiac Surgery as a Potential Determinant of Postoperative Atrial Fibrillation and Remodeling: Is SGLT2 Cotransport... by Rodrigo L. Castillo, Jorge Farías, Cristian Sandoval, Alejandro González-Candia, Esteban Figueroa, Mauricio Quezada, Gonzalo Cruz, Paola Llanos, Gonzalo Jorquera, Sawa Kostin, Rodrigo Carrasco

“…In heart failure (HF) patients undergoing cardiac surgery, an increased activity of mechanisms related to cardiac remodeling may determine a higher risk of postoperative atrial fibrillation (POAF). …”
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