Quinine Use and the Risk of Exacerbations of Chronic Obstructive Pulmonary Disease: A Nationwide Retrospective Registry Study by Vilstrup F, Sivapalan P, Eklöf J, Jordan A, Biering-Sørensen T, Sperling S, Jensen JUS

“…An unadjusted analysis on the unmatched population showed similar results (HR 1.475, 95% CI 1.39 to 1.56).Conclusion: In the current study, we found an association between the use of Quinine in patients with COPD and an increased risk of acute exacerbations and death. …”
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Design and experiment of a Long Range Autonomous Underwater Vehicle for Ocean Acoustic Data Observation by Sun Qindong, Xu Shangfeng, Sun Tongshuai, Lu Faliang, Dong Pengfei, Chang Jiaqi

“…In order to realise noise measurement and target detection, this paper designs a long range autonomous underwater vehicle (LRAUV), namely ‘Petrel’, which contains a variable buoyancy system, attitude adjustment mechanisms, pitch and heading control planes, acoustic vector sensor (AVS) and a propeller. …”
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Replacing fishmeal with an insect meal blend: Implications for intestinal microbiota in European seabass by Violeta Kalemi, Simona Rimoldi, Rafaela S. Costa, Ana Basto, Marta Monteiro, Genciana Terova, Luisa M.P. Valente

“…This research stands out by examining a combination of IMs rather than a single source, thereby addressing an underexplored area in the current literature. In a feeding trial that lasted 75 days, European seabass were fed three different diets: a commercial-like control diet and two experimental diets containing partial replacement of FM with IM (25 % and 50 %). …”
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Sarcopenia in Rheumatic Diseases: A Hidden Issue of Concern by Eleni C. Pardali, Markos Klonizakis, Dimitrios G. Goulis, Sousana K. Papadopoulou, Christos Cholevas, Constantinos Giaginis, Christina Tsigalou, Dimitrios P. Bogdanos, Maria G. Grammatikopoulou

“…The present narrative review seeks to explore the methods used to assess sarcopenia in patients with RDs, its prevalence among them, and the challenges faced by the affected individuals, while critically assessing the appropriateness and limitations of current sarcopenia assessment tools in the context of RDs.…”
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The lack of evidence-based management in electrical storm: a scoping review by Pouya Motazedian, Graeme Prosperi-Porta, Marie-Eve Mathieu, Nickolas Beauregard, William Knoll, Nicholas Quinn, Simon Parlow, Pietro Di Santo, Omar Abdel-Razek, Richard Jung, Nikola Kolobaric, William Barbour, David Nelson, Trevor Simard, Jacob C. Jentzer, Rebecca Mathew, George A. Wells, F. Daniel Ramirez, Benjamin Hibbert

“…The use of sedation for ES was exclusively studied in the context of mechanical ventilation. There was an increase in the number of ES studies over time, but sample sizes remained small and unchanged. …”
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A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy by Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He

“…Teriparatide (PTH1‐34) exerts antioxidant properties in the context of osteoporosis. Thus, in the current study, a multifunctional thermosensitive nanodelivery system is developed, based on the unique anatomical structure of the inner ear, to load and sustain the release of PTH1‐34 to alleviate hair cell damage. …”
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THE ANALOGY OF STATUTE AND THE ANALOGY OF LAW AS DOCTRINAL INSTRUMENTS FOR LEGAL RESPONSE TO ECONOMIC CHALLENGES by Serhii Zavalniuk, Volodymyr Zavalniuk, Iryna Zavalniuk

“…The analogy of statute (analogy legis) and the analogy of law (analogy iuris) hold a distinct place among the tools for overcoming legal gaps in the economic sphere. In the context of the global trend of expanding the scope of judicial discretion, the question of the admissibility and methodology of analogies is becoming increasingly critical. …”
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Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia by Ilinca Untu, Michael Davidson, Gabriela-Dumitrita Stanciu, Jonathan Rabinowitz, Jonathan Rabinowitz, Romeo-Petru Dobrin, Diana-Sabina Vieru, Bogdan-Ionel Tamba, Bogdan-Ionel Tamba

“…These mechanisms likely contribute to the acceleration of neurodegeneration in AD and the onset or worsening of depressive symptoms. Current therapeutic approaches remain largely nonspecific, with a lack of targeted therapies that address the unique pathophysiological context of depression in AD. …”
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Emergency response mobile 3D printing system: A case study in rapid manufacturing of polyurethane foam bridges by Jingwen Liang, Zhuo Zeng, Penglin Wang, Zhongxu Wang, Shifeng Wen, Yan Zhou, Cheng Zhou

“…In the context of increasing global natural disasters, the 72-hour golden rescue window imposes three critical requirements on rapid construction technologies: timeliness, multi-hazard adaptability, and systemic support. …”
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Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…CE-MS peptidome analysis identified 191 significantly altered peptides in severely injured patients. A consistent increase in the abundance of peptides from A1AT, AHSG, and HBA1 was observed, while peptides derived from PIGR and UROM were consistently decreased. …”
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Tokenization and deep learning architectures in genomics: A comprehensive review by Conrad Testagrose, Christina Boucher

“…Current deep learning architectures and tokenization techniques have been explored for the extraction of meaningful underlying information contained within this sequencing data. …”
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Assessment of Ecological City Development in Urban Settlements of East Azarbaijan Province with an Emphasis on the Theoretical Model of Sustainable Development by Hosain Nazmfar, Ali Eshghei charborj, Saeedeh Alavi

“…With the rapid increase in urban population in the world and increasing concern about the environment, the challenge of creating a livable sustainable city was a priority for city planners; the idea of the Ecology is in response to these concerns. …”
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Pearl River Delta: Scales, Times, Domains by Liang Xiong

“…It provides a substantial opportunity via visualization and spatialization to overcome the obstacle of localism among different levels of governments in the decision-making and implementation processes. It also helps to increase public awareness of, and participation in, the planning and design process, which are often lacking in the Chinese context. …”
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Family Interviews Improve Health Service Recommendations in Mortality Review Process: A Mixed‐Methods Assessment by Catherine Kothari, Fernando Ospina, Nia Evans, Cynthia Bane, Joi Presberry Dixon, Vaishali Patil, Ruth Butters, Rosemary Fournier, Susanna C. Joy, Brenda O'Rourke, Josephine Woods, Debra Lenz, Aaron L. Davies

“…Additionally, US policy leaders in maternal child health and health equity provided historical and current context for FIMR family interview funding and enabling legislation (informing the interpretation of study results and specifically referenced within the manuscript).…”
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Visual analysis of fruit harvesting machine based on CiteSpace by YANG Daorina, ZHANG Fengkui, WANG Yulong, HE Ruohong, ZHU Jikui, LI Ping

“…[Objective] In the context of the acceleration of agricultural modernization, the development of fruit harvesting machinery is of great significance for improving the production efficiency of fruit industry and reducing labor costs. …”
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Assessing carbon storage dynamics in an ecological civilization demonstration zone amid rapid urbanization: A multi-scenario study of Guizhou Province, China by Rui Chen, Xuehai Fei, Jingyu Zhu, Weiduo Chen, Haiqiang Du, Yingqian Huang, Yi Shen, Yong Zhang, Aping Niu, Peng Xu

“…The results show that Guizhou’s carbon storage increased from 3423.13 Tg to 3475.42 Tg, with forest restoration increasing it by 301.62 Tg and agricultural expansion reducing it by 218.63 Tg. …”
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Microbial Enhanced Heavy Oil Recovery by the Aid of Inhabitant Spore-Forming Bacteria: An Insight Review by Biji Shibulal, Saif N. Al-Bahry, Yahya M. Al-Wahaibi, Abdulkader E. Elshafie, Ali S. Al-Bemani, Sanket J. Joshi

“…As the price of crude oil increases and crude oil reserves collapse, exploitation of oil resources in mature reservoirs is essential for meeting future energy demands. …”
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PROBLEM ISSUES IN THE IMPLEMENTATION OF INNOVATIONS AND DIGITAL TECHNOLOGIES IN AGRICULTURAL PRODUCTION IN THE CONDITIONS OF NBIC CONVERGENCE by Marianna VASILCHENKO, Elena DERUNOVA, Anton VORONOV, Maria RGEVSKAYA

“…Currently, in the agro-industrial complex, the problem of import substitution of key technological solutions, innovative resources and digital technologies is becoming increasingly important for increasing agricultural production. …”
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Protocol for a prospective, observational, hospital-based multicentre study of nosocomial SARS-CoV-2 transmission: NOSO-COR Project by Hubert P Endtz, Mitra Saadatian-Elahi, Valentina Picot, Laetitia Hénaff, Florence K Pradel, Vanessa Escuret, Cédric Dananché, Christelle Elias

“…In France, mortality rate in the general population was approximately 10% and could reach higher levels at the hospital. In the current context of high incidence rates of SARS-CoV-2 in the community, a significant increase in the rate of nosocomial transmission is expected. …”
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