High dynamic range capillary electrophoresis method for sensitive detection of low-frequency driver mutations by Nobue Tamamura, Yoshihiko Hagiwara, Hirokazu Kato, Yusuke Ono, Kenji Takahashi, Kazuya Koyama, Hiroki Sato, Tetsuhiro Okada, Hidemasa Kawabata, Yu Ohtaki, Chiho Maeda, Miyuki Mori, Shin-ichi Chiba, Mishie Tanino, Kenzui Taniue, Takashi Anazawa, Ryoji Inaba, Yusuke Mizukami

“…Abstract Cancer genomics aims to personalize treatments by identifying genetic abnormalities in cancer cells. However, current analytical techniques face limitations in simplicity and cost-effectiveness. …”
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Medical embryology and regenerative medicine: research and applications in clinical practice by Julia Soczyńska, Julia Soczyńska, Wiktor Gawełczyk, Wiktor Gawełczyk, Patrycja Obrycka, Patrycja Obrycka, Mateusz Żołyniak, Mateusz Żołyniak, Adrian Muzyka, Adrian Muzyka, Krzysztof Majcherczyk, Krzysztof Majcherczyk, Julia Papierkowska, Julia Papierkowska, Sławomir Woźniak

“…Taking this progress a step further, the ability to introduce stem cells into damaged tissues, thereby facilitating the formation of functional structures, has led to the growing interest in organoids -three-dimensional models that replicate key functions of real organs. Organoids are currently applied not only in drug screening but are also gaining increasing attention for their role in cancer therapy research. …”
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Advancing life cycle assessment of bioenergy crops with global land use models by Anders Arvesen, Florian Humpenöder, Tomás Navarrete Gutierrez, Thomas Gibon, Paul Baustert, Jan Philipp Dietrich, Konstantin Stadler, Cristina-Maria Iordan, Gunnar Luderer, Alexander Popp, Francesco Cherubini

“…We find that land use-related CO _2 emission for bioenergy range from 2 to 35 tonne TJ ^−1 , depending on bioenergy demand, policy context, year and accounting method. GHG emissions per unit of bioenergy do not increase with bioenergy demand in presence of an emission tax. …”
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The Symbiotic Bacterial Profile of Laboratory-Reared and Field-Caught <i>Aedes albopictus</i> Mosquitoes from Greece by Elias Asimakis, Ioannis Galiatsatos, Georgia Apostolopoulou, Eleni C. Savvidou, Georgios Balatsos, Vasileios Karras, Vasiliki Evangelou, Eva Dionyssopoulou, Antonios Augustinos, Nikos T. Papadopoulos, Antonios Michaelakis, Panagiota Stathopoulou, George Tsiamis

“…The use of symbiotic bacteria to improve the application of SIT or design combined SIT/incompatible insect technique (IIT) approaches is currently considered. In this context, exploring the microbiota of local mosquito populations is crucial for identifying interesting components. …”
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Heat Removal Performance Analysis of HTR-PM Reactor Cavity Cooling System under Accident Condition by QIN Haiqi, LI Xiaowei, ZHANG Li, LIU Xiongbin, ZHENG Yanhua, WU Xinxin

“…When the atmosphere temperature increases from 25 ℃ to 42 ℃, the maximum concrete temperature increases from 86 ℃ to 111 ℃. …”
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The Effects of Creatine Monohydrate and/or Whey Protein on the Muscle Protein Synthesis and Anabolic Signaling Responses in Non-Stressed C₂C₁₂ Murine Myotubes by Nicholas J. Kontos, Joshua S. Godwin, Anthony Agyin-Birikorang, Darren G. Candow, Christopher M. Lockwood, Michael D. Roberts, Christopher B. Mobley

“…<b>Conclusions</b>: WP increases protein synthesis and anabolic signaling with no additive effect from CRE. …”
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Quantitative characterization of adsorbed and free shale oil microscopic distribution based on nuclear magnetic resonance: a case study of Chang 7 member of Triassic Yanchang Forma... by Fei LIU, Jinliang DU, Lin SUN, Ruiliang GUO, Bofei HAO, Peng LIU

“…Quartz-related pores significantly increase the specific surface area of pores, thus providing more occurrence sites for adsorbed oil, whereas an increase in clay mineral content significantly reduces the pore volume available for free oil. …”
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Efficacy and Safety of Various Intravenous Thrombolytics for Acute Ischemic Stroke (AIS) at Various Dosages: A Systematic Review and Network Meta-Analysis by Yibin Hu, Shengxian Wu, Haixuan Zhang, Kangfeng Wang, Lijuan Zhang, Yizheng Ma, He Li

“…Abstract Background Currently, there is limited evidence on the efficacy and safety of various thrombolytic drugs at different dosages for the treatment of acute ischemic stroke (AIS). …”
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A Comparison of the 𝜶2/3/5 Selective Positive Allosteric Modulators L-838,417 and TPA023 in Preclinical Models of Inflammatory and Neuropathic Pain by Sarah Nickolls, Hannah Mace, Rebecca Fish, Michelle Edye, Rachel Gurrell, Magnus Ivarsson, Tom Pitcher, Sachi Tanimoto-Mori, Denise Richardson, Catherine Sweatman, Janet Nicholson, Cameron Ward, John Jinks, Christine Bell, Kimberly Young, Huw Rees, Andrew Moss, Ross Kinloch, Gordon McMurray

“…GABAA receptors containing α2/3 subunits are current targets in the battle to develop new pain medications, as they are expressed in the spinal cord where increasing inhibitory drive should result in analgesia. …”
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The incidence of influenza in pregnant women and the relevance of possible preventive measures by A. Z. Khashukoeva, T. E. Dmitrashko, Z. A. Beslangurova, D. M. Lyafisheva

“…Currently, despite significant advances in the development of medicine in general, and diagnostic and therapeutic approaches in particular, the problem of influenza is still extremely relevant. …”
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The use of innovative technologies in the production of culinary products in public catering enterprises by E. S. Franchenko, M. Yu. Tamova, T. A. Dzhum, R. A. Zhuravlev, K. K. Nikanov

“…The article provides an overview of the types of raw materials containing increased amounts of digestible iron, and describes modern technologies for the production of culinary products for people suffering from anemia. …”
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Research hotspots and trends in the application of diffusion tensor imaging in ischemic stroke: a bibliometric analysis (2003–2024) by Xu Chen, Xu Chen, Meifang Liu, Xiaolin Yang, Mengqi Yue, Haocheng Yu, Haiqiang Wang, Zirong Wang, Jing Shi, Jing Shi, Yong Qiu

“…However, the current study still needs to strengthen cross-regional cooperation, and higher quality and broader research is still necessary to lay the foundation for reaching the consensus of various experts.…”
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Improved lubricating and corrosion resistance of MAO coatings on ZK61 Mg alloy by co-doping with graphite and nano-zirconia by Chao Yang, Liyuan Sheng, Chaochao Zhao, Pinghu Chen, Wentai Ouyang, Daokui Xu, Yufeng Zheng, Paul K. Chu

“…Compared with doping with a single element, co-doping increases the content of ZrO2 and graphite in the MAO coating. …”
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Impacts of climatology error on evapotranspiration data merging over the intensively irrigated Haihe river basin, China by Yuxi Li, Xi Chen, Jianzhi Dong, Jianhong Zhou, Xin Tian, Man Gao

“…New hydrological insights for the region: Results demonstrate that current RS and reanalysis datasets of ERA5, PML, and ALEXI contain strong intra and inter-annual biases. …”
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Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus by Carlos Enrique Torres-Méndez, Sharmilee Nandi, Klara Martinovic, Patrizia Kühne, Yifan Liu, Sam Taylor, Maria Lysandrou, Maria Ines Berrojo Romeyro Mascarenhas, Viktoria Langwallner, Javier Enrique Sebastián Alonso, Ivana Jovanovic, Maike Lüftner, Georgia-Vasiliki Gkountana, David Bern, Abdul-Raouf Atif, Ehsan Manouchehri Doulabi, Gemma Mestres, Masood Kamali-Moghaddam

“…Differential pulse voltammetry was used to measure the change in current across the electrode as a function of H1 concentration. …”
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Ginkgo ketone ester tablets for the treatment of cognitive impairment associated with chemotherapy for breast cancer - a prospective cohort study by Jiajing Chen, Lixin Chen, Kexin Jiang, Dandan Wang, Chunyu Wu, Yuenong Qin, Sheng Liu

“…BackgroundChemotherapy-related cognitive impairment (CRCI) affects up to 75% of breast cancer patients during treatment, with 35% experiencing persistent post-treatment deficits. Current interventions show limited efficacy, creating urgent need for targeted therapies. …”
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Biostimulation through natural biological inputs on fruiting, nutrient availability and rhizosphere microbiome in legume intercropped ‘Sweet Charlie’ strawberry (Fragaria × Ananass... by Pramod Kumar, Rajeshwar Singh Chandel, Subhash Chander Verma, Nisha Sharma, Simran Saini, Rohit Bishist, Suman Lata

“…Liquid microbial culture of Jeevamrit contained cow dung-urine (pH-5.65, EC-0.23 dS/m) and was enriched with Azotobacter chroococcum, Pseudomonas species and actinobacteria. …”
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Highly sensitive multiplex PCR for convenient quantification and differentiation of canine Oomycota pathogens: Pythium insidiosum, Lagenidium giganteum f. caninum, and Paralagenidi... by Asfiha Tarannum, Subarna Barua, Leonel Mendoza, Raquel Vilela, Priscilla Barger, Terri Hathcock, Amelia White, Kelly Chenoweth, Chengming Wang

“…Interestingly, the developed multiplex Oomycota PCR revealed that 45.5% (40/88) of serum samples positive for anti-Pythium antibody contained Pythium DNA. Additionally, among 24 suspected anti-Pythium antibody-positive samples, 54.2% (13/24) tested positive for Pythium DNA, while 8.3% (2/24) contained Lagenidium DNA. …”
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Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3 by Swapan Kumar Ghosh, Koushik Pandey, Madhuparna Ghosh, Pradip Kumar Sur

“…Abstract Globally the current research is going for cancer disease management by different strategies as frequency and severity of this disease are increasing day by day. …”
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Prevalence and associated factors of tuberculosis among diabetic patients attending public health facilities in Ethiopia: a multicenter study by Ayinalem Alemu, Getachew Seid, Getu Diriba, Michael Hailu, Biniyam Dange, Shewki Moga, Daniel Melese, Gemechu Tadesse, Solomon H Mariam, Nega Berhe, Balako Gumi

“…Abstract Background Individuals with diabetes mellitus (DM) have high tuberculosis (TB) prevalence. Currently, the incidence of DM is increasing in low and middle-income countries including Ethiopia where TB is also endemic, which may complicate TB prevention and control efforts. …”
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