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3621
Research progress on novel nanomaterials mediated treatment of candidal keratitis
Published 2025-04-01“…The incidence of Candida keratitis has been rising annually due to factors such as the misuse of immunosuppressive drugs and increased contact lens wear. Following infection, Candida itself and the formation of biofilms contribute to enhanced resistance against currently used systemic antifungal agents, including voriconazole, amphotericin B, itraconazole, and fluconazole,posing significant challenges to clinical treatment.Recently, research on nanomaterials-mediated drug delivery systems for treating Candida keratitis has burgeoned. …”
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3622
Chemotactic migration of T cells towards dendritic cells promotes the detection of rare antigens.
Published 2012-01-01“…Although it has been shown that dendritic cells (DCs) carrying cognate antigen in some circumstances attract T cells chemotactically, it is currently still unclear whether chemoattraction of T cells towards DCs helps or hampers scanning. …”
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3623
E-commerce as a modern form of business organization
Published 2024-12-01“…The development of e-commerce can increase the profitability of companies and allow them to reduce costs, in particular, virtual stores and online contact addresses allow goods to be stored closer to the place of their direct production, which speeds up the distribution of goods and related costs.…”
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3624
Two-Hour Sea Level Oscillations in Halifax Harbour
Published 2025-07-01“…We explore the nature of the oscillations as a first step towards the improvement of prediction schemes for sea level and currents in the region. This involves an analysis of the oscillations in the context of seiche and Helmholtz resonance theories and the use of a 2D numerical model to handle realistic bathymetric conditions and other complications that the simpler theories cannot address. …”
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3625
Residential Buildings at Climate Crossroads: Insights from Portugal for South European Energy Performance
Published 2025-05-01“…Results indicate substantial regional variations, with significant increases in cooling demands and corresponding reductions in heating needs, exposing limitations in the regulatory climate files currently used in energy certification processes. …”
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3626
Advances in research on SATB2 and its role in tumor development
Published 2025-07-01“…Understanding its precise mechanisms in these contexts can pave the way for future advancements in therapeutic strategies. …”
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3627
Federated learning with tensor networks: a quantum AI framework for healthcare
Published 2024-01-01“…The healthcare industry frequently handles sensitive and proprietary data, and due to strict privacy regulations, it is often reluctant to share it directly. In today’s context, Federated Learning (FL) stands out as a crucial remedy, facilitating the rapid advancement of distributed machine learning while effectively managing critical concerns regarding data privacy and governance. …”
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3628
NATIONAL HEALTH INSURANCE BASED TELEMEDICINE APPLICATION FOR HYPERTENSION MANAGEMENT IN PRIMARY LEVEL OF HEALTH FACILITIES
Published 2021-06-01“…Telemedicine is a health care provider without any direct contact, which has various methods. Today, telemedicine in Indonesia is growing rapidly along with technology and legal regulation in its implementation, increasing users by 700% in the first year of 2020. …”
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3629
Perceptions of AI competence in social and healthcare services: Readiness, reliance and realism
Published 2025-04-01“… Artificial intelligence (AI) is transforming the health and social service environment through increasingly advanced and autonomous digital solutions. …”
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3630
PULSE: A modular framework for predictive energy efficiency in heterogeneous data centers
Published 2025-09-01“…The platform fills a gap in current research by offering a user-friendly, modular, and adaptive solution that empowers operators to model, predict, and improve data center energy performance with minimal technical expertise. …”
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3631
Document-Level Neural TTS Using Curriculum Learning and Attention Masking
Published 2021-01-01“…During synthesis, the document-level text is synthesized using only the necessary contexts of the current time step and masking the rest through an attention-masking mechanism. …”
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3632
A novel in vitro system for simultaneous infections with hepatitis B, C, D and E viruses
Published 2025-05-01“…Using HEV-infected HuHep mice, we confirmed the antiviral effect of vonafexor, an FXR agonist, that is currently being tested clinically against HBV/HDV. …”
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3633
Participative Multilingual Identity Construction in Higher Education: Challenging Monolingual Ideologies and Practices
Published 2025-04-01“…In establishing a rationale for applying this framework and its underpinning conceptualisation of multilingual identity to the (increasingly linguistically diverse) tertiary education sector, this current paper critically examines the literature on attitudes towards multilingualism in higher education; and on evidence for the value of identity-focused pedagogies. …”
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3634
CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers
Published 2024-10-01“…CHAC1, an essential regulator of oxidative stress and ferroptosis, is increasingly recognized for its significant roles in these cellular processes and its impact on various human diseases and cancers. …”
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3635
Unit-level Digital Twin Model Construction Technology for Part Manufacturing Processes
Published 2025-02-01“…This paper reviews the construction technology of unit-level digital twins for part machining, focusing on three key aspects: virtual entity model construction, process strategy design, and process parameter decision making. The current research status and limitations of these aspects in both domestic and international contexts are discussed. …”
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3636
Prevalence and associated factors of tuberculosis among diabetic patients attending public health facilities in Ethiopia: a multicenter study
Published 2025-02-01“…Abstract Background Individuals with diabetes mellitus (DM) have high tuberculosis (TB) prevalence. Currently, the incidence of DM is increasing in low and middle-income countries including Ethiopia where TB is also endemic, which may complicate TB prevention and control efforts. …”
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3637
Optimal management of crop pests in the presence of agritourism
Published 2025-06-01“…The findings indicate that while pest management is crucial for reducing fruit damage and increasing yields, current practices fail to maximize economic returns. …”
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3638
Urban green infrastructure and social cohesion in Lagos Metropolis, Nigeria
Published 2024-12-01“…Urbanisation has increasingly resulted in social fragmentation, insecurity, and health challenges in cities worldwide. …”
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3639
OPTIMIZATION OF IMID-BASED THERAPIES
Published 2024-12-01“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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3640
Justification of military neutrality of the Republic of Serbia at a time of erosion of neutrality in Europe
Published 2023-01-01“…The first chapter briefly describes the historical decline of neutrality during the first half of the 20th century. In that context, observation made in mid last century, according to which neutrality was becoming an obsolete concept, is true. …”
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