Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT by Janey Sewell, T Charles Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger

“…Modelling suggested that provision of oral tenofovir/emtricitabine pre-exposure prophylaxis increased human immunodeficiency virus testing, with anti-retroviral therapy initiation at diagnosis, and reductions in the level of condom-less sex, that each played an important role in decreasing human immunodeficiency virus incidence among men who have sex with men, and that the current human immunodeficiency virus incidence would have been double what it is if any one of them had not occurred. …”
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Advancing the therapeutic effectiveness of paclitaxel in chronic lymphocytic leukemia through the simultaneous inhibition of NOTCH1 and SF3B1 by Shiva Abolhasani, Armin Mahmoud salehi Khesht, Atefeh Khodakarami, Ali Masjedi, Bentolhoda Rashidi, Sepideh Izadi, Fatemeh Karimian Noukabadi, Vahid Karpisheh, Khatereh Torabi Poudeh, Pooya Jalali, Zahra Salehi, Rafieh Bagherifar, Seyyed Sina Hejazian, AliAkbar Movassaghpour, Abbas Ali Hosseinpour Feizi, Farhad Jadidi

“…Results Our findings showed that CL-NPs loaded with anti-NOTCH1/-SF3B1 siRNAs-PTX significantly suppressed NOTCH1 and SF3B1 expression in PBMCs and BMMCs isolated from CLL cases in comparison with the untreated samples, leading to increased leukemic cell sensitivity to PTX and decreased the proliferative capacity of leukemic cells. …”
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Effect of 5-fluorouracil on Pseudomonas aeruginosa: impact on virulence, biofilm formation, and bacterial growth by Amani A. Niazy, May M. Alrashed, Abdurahman A. Niazy

“…By placing the current evidence in context, we hope to guide further studies toward determining the clinical viability of 5-FU as a treatment option against this formidable pathogen.…”
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High-tech agricultural tools as a determinant of dynamic rationalization of business processes in Russian agriculture by Moroz Oksana, Medvedsky Dmitriy

“…In the current environment of innovative transformations in the Russian Federation, there is a significant expansion of digital technological products, and there is an active digital optimization of business processes in all national economic sectors, including agriculture. …”
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Structural Validity and Reliability of the Indonesian Version of Self-Leadership by Gianti Gunawan, Anissa Lestari Kadiyono, Fasya Adisa Raspati

“…Background Problems: As self-leadership increasingly becomes recognized as a key factor in organizational success, there is a need for an assessment tool adapted to the Indonesian context. …”
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Toward a Capability-Based Account of Intergenerational Justice by Alex M. Richardson

“…It is my hope that the capabilities approach so applied can give us a novel way of understanding our responsibilities toward future people in a time where such an understanding is both unfortunately lacking and increasingly dire. Finally, I will discuss some implications of a capability-based account in the intergenerational context and some justifications for applying the approach in this way. …”
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Establishing foreign bookshelves in libraries around the world: a socio-cultural component of international cooperation by Demianiuk Liudmyla

“…The research has found that such projects are effective tools of cultural diplomacy that significantly enhance global cultural understanding. Conclusions. In the current geopolitical and cultural context, a pressing issue for Ukraine is the preservation of the identity of the Ukrainian nation and its cultural heritage for future generations. …”
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The Role of Gut Microbiota Dysbiosis as a Potential Factor in Early Diagnosis, Prognosis and Therapeutic Strategy of COVID-19 Patients by Kevin Tandarto, Kadek Ari Suyandi, Lily Chandrawati

“…The consequences of the coronavirus disease 2019 (COVID-19) are devastating and become the current world major public health issue. Not only SARS-CoV-2 attack the respiratory system, but also can affect multiple organs. …”
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Financial assessment of the implementation of state policy measures in the field of environmental protection: macroeconomic aspect by N. N. Shkolnikova, E. A. Shkolnikov, M. A. Shkolnikov

“…The assessment of expenditures for environmental protection in Russia for 2017–2021 showed an annual stable growth with an almost twofold increase in the whole five years. A structural analysis in the context of environmental protection activities allowed us to identify the dominant cost items as the most significant in the implementation of state environmental policy. …”
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Internal Control System of the Enterprise as Instrument for Ensuring Economic Security by A. V. Guryanov, V. A. Plotnikov, A. M. Yusufova

“…The article substantiates the need to introduce and develop internal control at an enterprise and examines the importance of the internal control system as a factor in increasing the economic security of an enterprise. The main objectives of the economic security of an enterprise in this context are identified as: timely identification and prevention of adverse events in the activities of the enterprise; ensuring compliance with current legislation; asset protection; control of the reliability of the reporting provided; carrying out analysis of the processes of economic activity of the enterprise. …”
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COVID-19 hardship and mental health in Chilean parents: the role of disaster exposure and family resilience by Camila Espinoza, Lenneke Alink, David P. Laplante, Bernet Elzinga, Shelley van der Veek

“…Background: The negative mental health effects of the pandemic on families are well documented, while factors that buffer or increase such effects still need further investigation. …”
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Organizational Support as Perceived by Staff Nurses and Its Relation to Their Autonomy by Ehsan S. S. Saad, Samah M. Elsayed

“… Context: Nurses need support at all levels in the organization. …”
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The Institution of Mediation in the Legislation of the Republic of Kazakhstan: Prospects for Regional Adaptation by N. S. Chimarov, S. Yu. Chimarov

“…The presence of a stable and often conservative system of judiciary organizations is not fully compatible with the ever-increasing volume of cases, the complexity of which is also naturally increasing. …”
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Transition to the sustainable supply chains: (on the example of PJSC Uralkali) by Strimovskaya Anna, Ryumkina Kseniya, Presnyakova Olga

“…In the context of economic globalization and the growing number of sanctions, certain issues of managing key business processes, export operations and logistics in general become especially relevant for domestic enterprises. …”
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Reducing Delivery Times by Utilising On-Site Wire Arc Additive Manufacturing with Digital-Twin Methods by Stefanie Sell, Kevin Villani, Marc Stautner

“…The increasing demand for smaller batch sizes and mass customisation in production poses considerable challenges to logistics and manufacturing efficiency. …”
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Environmental Impact Sukuk: A Proposal for Environmental Sustainability by Ahmet Ulusoy, Mehmet Ela

“…The effects of climate change have been increasing rapidly in recent years and attracting attention in the context of a global problem. …”
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What ‘unexplored’ means: mapping regions with digitized natural history records to look for ‘biodiversity blindspots’ by Laymon Ball, Sheila Rodríguez-Machado, Diego Paredes-Burneo, Samantha Rutledge, David A. Boyd, David Vander Pluym, Spenser Babb-Biernacki, Austin S. Chipps, Rafet Ç. Öztürk, Yahya Terzi, Prosanta Chakrabarty

“…We also argue for increased scientific infrastructure so that more reference collections with vouchers can be kept in the countries of origin (particularly those countries lacking such infrastructure currently).…”
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HORMONE IMBALANCE AS A MANIFESTATION OF STRESS IN THE FORMATION OF OLIGOMENORRHEA IN TEENAGE GIRLS by В. Диннік, О. Диннік, С. Новохатська

“…At OM onset, nearly 20% of participants exhibited low E2 levels. With increased disease duration (years 2–3), the proportion of adolescents with low E2 decreased while those with elevated E2 increased. …”
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Residential Buildings at Climate Crossroads: Insights from Portugal for South European Energy Performance by Alexandre Castro, Sandra Sorte, Vera Rodrigues, Nelson Martins

“…Results indicate substantial regional variations, with significant increases in cooling demands and corresponding reductions in heating needs, exposing limitations in the regulatory climate files currently used in energy certification processes. …”
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Advances in research on SATB2 and its role in tumor development by Ge Cheng, Chi Tian, Waner Wang, Yangyang Zhou, Xiaoqing Wang, Lei Zhang

“…Understanding its precise mechanisms in these contexts can pave the way for future advancements in therapeutic strategies. …”
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