The methyl-CpG binding domain 2 regulates peptidylarginine deiminase 4 expression and promotes neutrophil extracellular trap formation via the Janus kinase 2 signaling pathway in e... by Biao Peng, Mu-Yun Yan, Yun-Rong Chen, Fei Sun, Xu-Dong Xiang, Da Liu

“…Objective The prognosis for severe asthma is poor, and the current treatment options are limited. The methyl-CpG binding domain protein 2 (MBD2) participates in neutrophil-mediated severe asthma through epigenetic regulation. …”
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Exome sequencing reveals a rare damaging variant in GRIN2C in familial late-onset Alzheimer's disease by Elisa Rubino, Maria Italia, Elisa Giorgio, Silvia Boschi, Paola Dimartino, Tommaso Pippucci, Fausto Roveta, Clara Maria Cambria, Gabriella Elia, Andrea Marcinnò, Salvatore Gallone, Ekaterina Rogaeva, Flavia Antonucci, Alfredo Brusco, Fabrizio Gardoni, Innocenzo Rainero

“…Primary rat hippocampal neurons overexpressing GluN2CA1072V showed an increase in NMDAR-induced currents, suggesting altered glutamatergic transmission. …”
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A review of coal mine saline mine water treatment and utilization technologies by Weidong MAO, Zhongquan GUO, Yuan FU, Jiuli YANG, Xufeng XU, Yantao WU, Zhipeng TANG, Jun ZHANG, Dongfeng CUI, Junzhao ZHU

“…Concerning the challenges currently faced by membrane concentration and evaporation crystallization technology, and the future development direction, the following proposals are put forward: the ongoing advancement of high-efficiency short-flow membrane concentration and low-carbon evaporation crystallization processing technology and equipment; the sustained investigation of the conversion of low-value by-product salts and the extraction of high-value components; actively explore the joint treatment mode of low-grade heat source, geothermal or photovoltaic power and salt-containing mine water; proactively investigate the regional centralized treatment mode of salt-containing mine water; and explore the technical, policy and economic feasibility of off-grid new energy applications, and study naturally enhanced evaporation and concentration technologies.…”
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Potential Herb-Drug Interactions Among Elderly Nursing Home Residents in Romania by Hanna Sebesi, László István Bába, Melinda Kolcsár, Zsolt Gáll, Soma Dávid

“…Evidence shows that herb-drug interactions (HDIs) are significant in clinical pharmacology. However, the current use of herbal supplements and the prevalence of HDIs among elderly patients in nursing homes is not known. …”
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Food Application of Orange Seed Powder through Incorporation in Wheat Flour to Boost Vitamin and Mineral Profiles of Formulated Biscuits by Ashiq Hussain, Salah Laaraj, Tusneem Kausar, Aziz Tikent, Hanane Azzouzi, Samina Kauser, Qurat Ul An, Aqsa Iqbal, Saima Akram, Rizwan Nisar, Ayesha Najam, Haya Fatima, Shazia Yaqub, Kaoutar Elfazazi

“…As a result, there is increasing interest in fruits and vegetable seeds that contain bioactive chemicals, such as those that are obtained from orange seeds. …”
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Interaction effect analysis of distributed photovoltaic access to distributed network based on single-port reduced model by Xiankui WEN, Ke ZHOU, Junwei ZHANG, Mingjun HE, Yongxiang CAI

“…A high penetration photovoltaic distribution network contain numerous voltage-sensitive power electronic devices, which effect with each other, increasing the computational complexity of the node grid-connected critical capacity. …”
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A review on the chemical ecology of the Fucaceae holobionts: from fundamental knowledge to applications by Rousseau, Coralie, Demoulinger, Gautier, Rousvoal, Sylvie, Champeval, Delphine, Dolly, Maurane, Michel, Gurvan, Thomas, François, Markov, Gabriel V., Potin, Philippe, Dittami, Simon M., Prado, Soizic, Leblanc, Catherine, Le Guillard, Cécile

“…In recent years, the use of brown seaweeds (Phaeophyceae) and especially Fucaceae, has increased for a variety of applications including food additives, nutraceuticals, cosmetics, and agriculture, mainly because most edible brown algae contain valuable bioactive compounds. …”
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Principles of care for adolescent girls with eating disorders and body disturbances disorders: lessons from the COVID-19 pandemic by A. A. Pichikov, Y. V. Popov, Y. A. Yakovleva, T. A. Salomatina

“…The most reasonable approaches during the pandemic are the approaches focused on the family of a teenager using, if possible, remote forms of assistance.Conclusions: Currently, there are no norms and standards in the organization of assistance to adolescents with eating disorders and body image disorders in the pandemic context. …”
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Compilation of the strategic model of the sanctions policies of the United States towards the Islamic Republic of Iran with an emphasis on three major security discourses (Joe Bide... by Jamshid Rezaei Mirghaed, Rohollah Shahabi, Fereydoon Akbarzadeh

“…The hypothesis of the authors or the central sign of the current article emphasizes the fact that the macro discourse of the United States in this period includes stopping policies, containment by delaying the domestic development of peaceful nuclear knowledge of Iran, destabilizing internal security and public order, disrupting the regionalist policies of the Islamic Republic of Iran. …”
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Boosting energy storage performance of ZnCoTe@NiCoSe2 with core-shell structure as an efficient positive electrode for fabrication of high-performance hybrid supercapacitors by Shiva Moraveji, Lida Fotouhi, Saeed Shahrokhian, Mohammad Zirak

“…ZnCoTe@NiCoSe2 has an excellent specific capacity of 240 mAh g−1 at a current density of 2 A g−1 in a three-electrode system containing 3 M KOH electrolyte solution, which is much superior to each of the core and shell components of the constructed electrodes. …”
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Psychological Features of 7-8 Grade Students Interaction with Hypertext: A Theoretical and Experimental Study Using an Eye Tracker by N.A. Borisenko, A.A. Ganicheva, K.V. Mironova, S.V. Shishkova

“… <p><strong>Context and relevance.</strong> Currently, hypertext systems are beginning to play an increasingly important role both in the media and in the educational process. …”
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Creatine as a Compound and Supplement Metabolism, Mechanism of Action, Effects, and Adverse Effects - A Review by Szymon Szypulski, Aleksandra Zielińska, Sebastian Iwaniuk, Ignacy Maciejewski, Kinga Tylczyńska, Jakub Skiba, Maria Michalska, Kinga Kowalik, Zuzanna Skiba, Natalia Tylczyńska

“…Over time, attention has also shifted toward exploring creatine’s potential applications in other areas of medicine, as well as its use across various populations and age groups. Currently, the significance and importance of creatine are being highlighted not only in the context of its use across various sports disciplines, but also for its demonstrated beneficial effects in a range of medical conditions. …”
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Challenges and Obstacles in the Development of Winter Sports Tourism in the Ski Slopes of Tehran by Siavash Imeni, Leyla Asadpour Shirazi

“…The ski industry forms a cluster combining skiing, ski entertainment, ski technology, and ski culture (Liu et al., 2022). Currently, there are 68 countries worldwide offering snow-covered outdoor ski areas, with approximately 2,000 ski resorts identified globally (Vanat, 2020). …”
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Factors affecting the design of the management dashboard framework with an emphasis on the components of human resources productivity by Hassan Barmaki, Farshad Faezy Razi, Ehtesham Rashidi

“…It collects information gathered from all departments of the organization, which contains various sources related to various business functions. …”
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Trimethylamine oxide and its possible role in the development and progression of cardiovascular disease by A. I. Kochetkov, M. V. Klepikova, O. D. Ostroumova

“…In view of this, large-scale randomized clinical trials are needed to study the CVR profile in patients receiving such therapy. Currently, other hepatoprotective agents are available that are devoid of such potential risks, since they do not contain PLs. …”
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Contributory Risk Factors for Hypertension in Adolescent Offsprings of Hypertensive Fathers Attending a Tertiary Hospital in Lagos by Babatunde A. Akodu, Victor A. Inem, Stephen Yohanna, Jane N. Ajuluchukwu

“…RESULTS: Among the adolescents whose fathers were hypertensives, 45.3% were current drinkers of coffee, and 76.7% were users of caffeine containing drugs while among the controls, 35.1% were drinkers of coffee and 52.8% were current users of caffeine containing drugs (P. value < 0.05). …”
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The prognostic value of serum apolipoprotein A1 levels in elderly patients with de novo SARS-CoV-2 omicron infection by Cong Shi, Ruishuang Ma, Miao Zhou, Shujun Yang, Shengping Gong

“…Additionally, we observed a significant increase in C-reactive protein (CRP) and beta-2 microglobulin (β2-MG) levels in individuals with decreased ApoA1 levels. …”
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The Association Between Traumatic Brain Injury and the Risk of Cognitive Decline: An Umbrella Systematic Review and Meta-Analysis by Ioannis Mavroudis, Dimitrios Kazis, Foivos Efstratios Petridis, Ioana-Miruna Balmus, Vasileios Papaliagkas, Alin Ciobica

“…Background: There is currently increasing interest in the implication of traumatic brain injury (TBI) as a potential risk factor for long-term neurodegenerative conditions, such as dementia and Alzheimer’s disease (AD). …”
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The role of judicial authorities in criminal proceedings for political crimes in the Stalinist period: modern historiography by Alexander Ya. Kodintsev

“…Currently, PhD theses, covering an increasing number of regions of Russia, are being defended actively. …”
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Features of mammary gland morphology in domestic carnivores by T. Kot, A. Dubovyi, Y. Liakhovchuk

“…According to diestrus, due to an increase in progesterone levels, successive morphological changes occur, in particular, stromal and ductal proliferation; early development of lobules with branching ducts and proliferation of alveoli; the dominance of glandular tissue with large lobules containing secretory material; early regression, an increase in interparticle connective tissue, eosinophilic protein secretion in dilated ducts and alveoli. …”
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