Polycystic Ovary Syndrome and the Potential for Nanomaterial-Based Drug Delivery in Therapy of This Disease by Mingqin Shi, Xinyao Li, Liwei Xing, Zhenmin Li, Sitong Zhou, Zihui Wang, Xuelian Zou, Yuqing She, Rong Zhao, Dongdong Qin

“…Polycystic ovary syndrome (PCOS) is the predominant endocrine disorder among women of reproductive age and represents the leading cause of anovulatory infertility, which imposes a considerable health and economic burden. Currently, medications used to treat PCOS can lead to certain adverse reactions, such as affecting fertility and increasing the risk of venous thrombosis. …”
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Hydroxyapatite-filled osteoinductive and piezoelectric nanofibers for bone tissue engineering by Frederico Barbosa, Fábio F. F. Garrudo, Paola S. Alberte, Leonor Resina, Marta S. Carvalho, Akhil Jain, Ana C. Marques, Francesc Estrany, Frankie J. Rawson, Carlos Aléman, Frederico Castelo Ferreira, João C. Silva

“…The biological cues provided by the HAp nanoparticles enhanced the osteogenic differentiation of seeded human mesenchymal stem/stromal cells (MSCs) as observed by the increased ALP activity, cell-secreted calcium deposition and osteogenic gene expression levels observed for the HAp-containing fibers. …”
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Enhanced Broad-Spectrum Efficacy of an L2-Based mRNA Vaccine Targeting HPV Types 6, 11, 16, 18, with Cross-Protection Against Multiple Additional High-Risk Types by Kosuke Tsukamoto, Akio Yamashita, Masatoshi Maeki, Manabu Tokeshi, Hirotatsu Imai, Akira Fukao, Toshinobu Fujiwara, Koji Okudera, Nobuhisa Mizuki, Kenji Okuda, Masaru Shimada

“…Results: We identified that a construct containing E01 (a 5′-untranslated region) and SL2.7 (a poly(A) polymerase recruitment sequence) significantly increased protein expression. …”
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Formulation of best-fit hydrophile/lipophile balance-dielectric permittivity demulsifiers for treatment of crude oil emulsions by C.M. Ojinnaka, J.A. Ajienka, O.J. Abayeh, L.C. Osuji, R.U. Duru

“…The presence of water in crude oil causes corrosion, lowers capacity utilization of production and processing plant parts and pipelines, reduces oil recovery and increases the oil content of the effluent water. The stabilizing factors of crude oil emulsions vary from one oil field to the other and with time in the same well as co-produced water increases, or after a well treatment and Enhanced Oil Recovery Operations (EOR). …”
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Advances in Encapsulating Marine Bioactive Compounds Using Nanostructured Lipid Carriers (NLCs) and Solid Lipid Nanoparticles (SLNs) for Health Applications by Rita Favas, Hugo Almeida, Andreia F. Peixoto, Domingos Ferreira, Ana C. Silva

“…As life expectancy rises and modern lifestyles improve, there is an increasing focus on health, disease prevention, and enhancing physical appearance. …”
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Treatment Methods Dry Form of Age Macular Degeneration — History and Prospects. Review by A. N. Kulikov, M. V. Zakharov, A. A. Volozhev

“…The main treatment for wet AMD is the injection of medications called anti-VEGF agents. Currently, treatment of dry age-related macular degeneration includes modification of risk factors (stop smoking, healthy life style and etc) and dietary supplements containing a combination of certain ingredients (vitamin C, vitamin E, zinc, copper, and lutein with zeaxanthin or beta-carotene) may be able to slow the progression of the disease. …”
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A virus becomes a global concern: research activities on West-Nile virus by Doris Klingelhöfer, Markus Braun, Isabelle M. Kramer, Friederike Reuss, Ruth Müller, David A. Groneberg, Dörthe Brüggmann

“…Currently, West-Nile virus (WNV) is spreading worldwide to colder regions due to climate change. …”
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One-sample missing DNA-methylation value imputation by Christelle Kemda Ngueda, Julia Palm, Flavia Remo, André Scherag, Lutz Leistritz

“…Abstract Background Currently, the most popular methods for missing DNA-methylation value imputation rely on exploiting methylation patterns across multiple samples from the same population. …”
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HISTORICAL CHANGES IN THE AREA UNDER FOREST—ESTIMATION APPROACH BASED ON CARTOGRAPHIC RESOURCES by Aleksandar Popović, Biljana Šljukić, Dragan Borota

“… This paper analyzes changes in forested areas, as depicted in topographic maps, within the historical context of their publication in Serbia. The research focuses on the experimental field “Goč-Gvozdac” of the University of Belgrade – Faculty of Forestry, with additional reference to changes in Central Serbia. …”
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The Role of Internet Penetration in Agricultural Development, Economic Growth and Development Index by Muh. I lham, Muh. Natsir, Gamsir Gamsir

“… The development of the internet and ICT-based technology (Information and Communication Technology) is currently the main focus of research, especially in the context of agricultural development which is expected to contribute to economic growth and the Human Development Index (HDI). …”
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Entropy-Based Uncertainty in Onshore and Offshore Wind Power: Implications for Economic Reliability by Fernando M. Camilo, Paulo J. Santos, Armando J. Pires

“…In Portugal, wind energy already accounts for approximately 30% of the total installed capacity, with projections reaching 38% by 2030, making it the country’s second largest energy source. In the context of the 2050 carbon neutrality targets, quantifying and managing wind power uncertainty has become increasingly important. …”
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Environmental and Economic Impacts of V2X Applications in Electric Vehicles: A Long-Term Perspective for China by Yajie Hu, Richao Cong, Toru Matsumoto, Yajuan Li

“…Electric vehicles (EVs) play a critical role in the transition to transportation electrification and are important for achieving carbon neutrality in this sector. China currently leads the world in EV ownership; however, the energy regulation potential of in-use batteries remains largely untapped in the context of an increasingly saturated EV stock. …”
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Dissertation council in the state scientific certification system: Organizational and management mechanisms of digital transformation by Sergey I. Pakhomov, Elena A. Loginova, Oleg V. Kulyamin, Mikhail P. Petrov

“…Currently, there is a need to refine the underlying mechanisms of dissertation councils as key elements of the state scientific certification system in Russia. …”
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Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case-control study and meta-analysis. by Danielle Fitzpatrick, Kirstin Pirie, Gillian Reeves, Jane Green, Valerie Beral

“…<h4>Background</h4>Current or recent use of combined oral contraceptives (containing oestrogen+progestagen) has been associated with a small increase in breast cancer risk. …”
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Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer by Linjie Xu, Xiaotian Yu, Haoming Luo, Jili Wang, Wenjie Liang, Jing Zhang, Zunlei Feng, Cheng Lu, Xiuming Zhang

“…Moreover, pixels in each whole-mount slide of PCa are increased by approximately <inline-formula> <tex-math notation="LaTeX">$4\sim 9$ </tex-math></inline-formula> times, therefore containing more information for diagnosis. …”
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Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT by Jon Wilson, Viktoria Cestaro, Eirini Charami-Roupa, Timothy Clarke, Aoife Dunne, Brioney Gee, Sharon Jarrett, Thando Katangwe-Chigamba, Andrew Laphan, Susie McIvor, Richard Meiser-Stedman, Jamie Murdoch, Thomas Rhodes, Carys Seeley, Lee Shepstone, David Turner, Paul Wilkinson

“…However, alterations to the referral pathways did not increase the number of referrals made to the study. …”
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iPSC models of mitochondrial diseases by Sonja Heiduschka, Alessandro Prigione

“…Consequently, most mitochondrial diseases are currently untreatable. Human induced pluripotent stem cells (iPSCs) represent a promising approach for developing human model systems and assessing therapeutic avenues in a patient- and tissue-specific context. iPSCs are being increasingly used to investigate mitochondrial diseases, either for dissecting mutation-specific defects within two-dimensional (2D) or three-dimensional (3D) progenies or for unveiling the impact of potential treatment options. …”
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Enhancing digital literacy in primary education through augmented reality by Natalie Nevrelova, Lilla Korenova, Zsolt Lavicza, Nikola Bruzkova, Angelika Schmid

“…Currently, there is a need to develop digital competencies already because they are included in the new curriculum. …”
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The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

“…Bioinformatics analysis showed Cti6 is conservative in Aspergillus spp., and mCherry mediated subcellular localization showed that most Cti6 accumulated in the nuclei, which reflected that Cti6 performed its important biological function in the nuclei in Aspergillus spp.. The results of the current study elucidate the roles of PHD domain containing proteins in the mechanism of the infection of crops by A. flavus, and provided a novel target for effectively controlling the contamination of Aspergillus spp. to crops.…”
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C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation by Tsung-Ta Liu, Cheng-Tsung Liu, I-Hsun Li, Yu-Chieh Chu, Hao-Yuan Hung, Chuang-Hsin Chiu, Ta-Kai Chou, Shiao-Yun Li, Tin-An Wang, Jui-Hu Shih

“…Abstract Background Parkinson’s disease (PD) is an incurable neurological disorder, and current pharmacological therapies primarily address symptoms without halting disease progression. …”
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