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3481
Biomarkers as Potential Treatment Targets in Inflammatory Bowel Disease: A Systematic Review
Published 2015-01-01“…CRP and hemoglobin levels can be used to help predict clinical relapse in the context of withdrawal of therapy. Ultimately, the authors conclude that currently available biomarkers should not be used as treatment targets in inflammatory bowel disease because they have inadequate operational characteristics to make them safe surrogates for clinical, endoscopic and radiographic evaluation. …”
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3482
Alternative Methods of Vaccine Delivery: An Overview of Edible and Intradermal Vaccines
Published 2019-01-01“…Despite the tremendous value conferred by currently available vaccines toward public health, the implementation of additional vaccine platforms is also of key importance. …”
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3483
Alternatives to Traditional Physical Science Laboratory Experiences: A Review
Published 2024-12-01“…A summary list of advantages (e.g., increased flexibility and access) and disadvantages (e.g., no face-to-face contact and some additional costs) outlined in the articles is presented. …”
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3484
From Traditional Product Lifecycle Management Systems to Blockchain-Based Platforms
Published 2022-06-01“…However, this practice results in reducing the overall system efficiency. In this context, this paper assesses and recommends a blockchain-based innovative solution that overcomes the challenges of existing PLMs, hence increasing the overall system efficiency. …”
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3485
El divorcio en Europa en el primer tercio del siglo XX. Una conquista de la democracia y la modernidad
Published 2025-04-01“…The debate on divorce ended up becoming generalised in the international context with increasingly permissive laws that facilitated new ideological currents that questioned the established order and the traditional marriage system and which required doctrinal and legal support to establish and consolidate the different positions.…”
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3486
Passivation of a Conductive System of Integrated Circuits with a Layer of Aluminum Nitride
Published 2023-06-01“…Passivation of the film conductive system of integrated circuits makes it more reliable by increasing the resistance to electromigration. The problem of manufacturing a passivating layer on the formed current-conducting system of an integrated circuit, obtained in a single technological cycle, including isotropic plasma-chemical etching of an aluminum alloy layer to a depth of 8–12 nm and isotropic plasma-chemical nitriding of the surface of the obtained current-carrying tracks until the aluminum nitride thickness from 10 to 50 nm, is considered. …”
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3487
Anatomic and mechanical considerations in restoring volume of the face with use of hyaluronic acid fillers with a novel layered technique
Published 2014-01-01“…Context: Facial fillers have revolutionized the field of cosmetic facial rejuvenation as it has become the prime sought - after rejuvenation procedure offering youthful, 3-dimensional look with minimal invasiveness. …”
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3488
Towards Explainable Pedestrian Behavior Prediction: A Neuro-Symbolic Framework for Autonomous Driving
Published 2025-06-01“…Currently, the focus of such predictions extends beyond accuracy and reliability, placing increasing emphasis on the explainability and interpretability of the models. …”
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3489
Standardized Outcomes for Randomized Controlled Trials Targeting Early Interventions in Patients With Moderate-to-Severe Traumatic Brain Injury: Protocol for the Development of a C...
Published 2025-01-01“…In the last 20 years, there has been an increase in clinical trials in neurocritical care, leading mostly to negative results. …”
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3490
Explorative Study of Modulatory Effects of Notochordal Cell‐Derived Extracellular Vesicles on the IL‐1β‐Induced Catabolic Cascade in Nucleus Pulposus Cell Pellets and Explants...
Published 2025-03-01“…Modification of the CCL2 secretion seemed to be context dependent in the human explants: where EVs treatment stimulated CCL2 secretion but in the presence of IL‐1β this effect was counteracted. …”
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3491
High prevalence of the hotspot complement factor I p.Ile357Met pathogenic variant in Tunisian atypical hemolytic uremic syndrome patients: report of three new cases and review of t...
Published 2025-08-01“…The recurrence of this variant in the Tunisian cohort led us to suggest that it could be characteristic of the Tunisian population.MethodsIn this context, we conducted the current study which included 8 adults and three children with suspected aHUS and decreased factor I levels, as well as one relative. …”
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3492
Immunotherapy in Advanced Cutaneous Melanoma: From the Optimal Treatment Duration to the Impact on Survival in Case of Early Discontinuation Due to Immune-Related Adverse Events
Published 2025-04-01“…Immunotherapy (IT) is generally well tolerated, but an increasing area of investigation concerns the optimal treatment duration of anti-programmed cell death-1 (anti-PD1) regimens to limit the immune-related adverse events in patients who obtained a clinical response. …”
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3493
European orthopaedic trauma registries: perspectives from Belgium, Greece, Germany, the Netherlands, Spain, and the United Kingdom
Published 2025-08-01“…Member countries of the International Orthopaedic Trauma Association were contacted to provide information on the development, current position, and future plans for trauma registries within their countries. …”
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3494
Circle of Security - Parenting: A Systematic review on Effectiveness of use of the parent training program within Multi-problem Families
Published 2021-01-01“…Introduction: Circle of Security-parenting (COS-p) is a simplified, relationship-based programme with the intention of developing parents’ observation and inferential skills related to understanding their child’s needs, increasing sensitivity to their child, aiding in emotional regulation, as well as decreasing any of their negative attributions to their child. …”
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3495
Developing the European Villages in the Republic of Moldova taken into account the Digital Economy Society Index (DESI)
Published 2023-06-01“…Recent positive experiences of EU member states, which have been analyzed in previous research papers, show that the creation of jobs in agricol sectors in rural areas contributes to increasing household incomes. The objective of our study is to analyze and implement the methods and data sources for calculating DESI indicators at the level of local administrative units in the Republic of Moldova, in the context of the National Program for the European Village, launched in spring 2022. …”
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3496
Developing the European Villages in the Republic of Moldova taken into account the Digital Economy Society Index (DESI)
Published 2023-06-01“…Recent positive experiences of EU member states, which have been analyzed in previous research papers, show that the creation of jobs in agricol sectors in rural areas contributes to increasing household incomes. The objective of our study is to analyze and implement the methods and data sources for calculating DESI indicators at the level of local administrative units in the Republic of Moldova, in the context of the National Program for the European Village, launched in spring 2022. …”
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3497
Évaluer ex ante la pertinence de projets locaux d’adaptation au changement climatique
Published 2012-11-01“…Yet, such bases are essential pillars for ensuring consistency among scattered adaptation initiatives, while these latter are expected to grow in number in the context of adaptation funds increase. (iii) Ex ante assessments are as necessary as currently dominating ex post assessments, as they contribute upstream and in parallel of projects’ monitoring and efficiency analysis, to the coherence and the optimisation of adaptation endeavours.…”
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3498
Research on the Urban Village Renewal Mechanism Based on Rent Gap Theory: A Case Study in Xi’an, China
Published 2025-01-01“…This paper proposes a rent gap theory that is more suited to China’s context and further expands its applicability through case study research. …”
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3499
Liquid Modernity and the Holocaust
Published 2022-01-01“…I emphasise that, according to Bauman, both moral indifference and xenophobia are increasingly significant phenomena in contemporary society, which may entail pernicious – and currently barely foreseeable – consequences. …”
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3500
From Surveillance to Sentencing: Evaluating AI's Role in Indian Criminal Justice
Published 2025-06-01“…Additionally, AI shows promise in addressing cybercrime, one of the most formidable challenges currently facing Indian authorities. However, the integration of AI into criminal investigations raises critical concerns regarding privacy, surveillance, data protection, and algorithmic bias. …”
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