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MicroRNA-32-5p inhibits metastasis by directly targeting VPS4B and increases sensitivity to dihydroartemisinin in neuroblastoma
Published 2024-09-01“…The primary objective of the current investigation was to characterize a newly discovered microRNA, miR-32-5p, in terms of the functional role, underlying mechanism of action, and potential synergistic therapeutic impact in the context of NB metastasis. …”
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Main factors influencing the digital economy: a literature review
Published 2024-12-01“…In response to the challenges of our time, our research aims to understand and analyse the trends of digitalization of the economy in the current context. It is important to note that this topic is becoming increasingly relevant in the context of the rapid development of technology and its impact on the global economy as a whole. …”
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Increasing uptake of self-management education programmes for type 2 diabetes in primary care: the Embedding research programme including an RCT
Published 2025-02-01“…Key recommendations for research Consider how best to increase uptake to SSME within the new context of increased focus on digital/virtual modalities due in part to the COVID-19 pandemic, while maintaining the benefits to some underserved populations without alienating others and widening disparities (e.g. those without internet access). …”
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The conflict between theory and practice in caring for children: field narrative of a social worker
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Evaluation of four KCNMA1 channelopathy variants on BK channel current under CaV1.2 activation
Published 2024-12-01“…Only the N999S mutation produced an increase in BK current in both micro- and nano-domains using square voltage commands and was also detectable in BK current evoked by a neuronal action potential within a microdomain. …”
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Design of an Improved Model for Personalized Adaptive E-Learning Using Context-Aware Federated Learning and Hierarchical Semantic Graph Analysis
Published 2025-01-01“…The challenges faced by most traditionally adaptive systems include limited personalization, context unawareness, low explanation, and reliance on shallow metrics of engagement. …”
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Scenari- Based Planning and Its Application in Sustainable Urban Regeneration (Case Study: Deteriorated Urban Context of Dargahan, Qeshm Island)
Published 2022-07-01“…The scope and depth of this challenge increase every day due to a wonderful mixture of ambiguity, complexity, uncertainty, and tsunamis of change surrounding the city and the current world. …”
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The molecular mechanism of shade avoidance in crops – How data from Arabidopsis can help to identify targets for increasing yield and biomass production
Published 2017-06-01“…This shade avoidance response (SAR) typically includes increased stem elongation at the expense of plant fitness and yield, making it an undesirable trait in an agricultural context. …”
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‘Can Remote Trials be Fair Trials? Exploring the Potential Effects of Communication Technology in the Criminal Justice Context from an Interdisciplinary Perspective’
Published 2024-11-01“…Exploring the Potential Effects of Communication Technology in the Criminal Justice Context from an Interdisciplinary Perspective’. This Special Issue explores the increasing use of remote technology in criminal proceedings, a trend largely attributed to the COVID-19 epidemic. …”
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