Immunological and physiological changes of exercise-released lactate on tumors: an important and new research window by Amir Hossein Ahmadi Hekmatikar, Arsham Entesari, Hossein Shirvani

“…In the cancer immune cycle, the immune checkpoint PD-1 and its ligand PD-L1 collaborate to facilitate immune escape and promote tumor progression (Keir et al., 2008). In this context, a study revealed that lactate can enhance the expression of PD-L1 on tumor cells, suggesting that lactate may have a protective effect against tumors by increasing PD-L1 expression (Feng et al., 2017). …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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Comparative Ethics of Modern Payment Models by Jacob Riegler

“…This article examines the alignment of current predominant payment models of fee-for-service, capitation, and value-based payments with patient care ethics. …”
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Comparación de dos métodos de detección para el registro de la frecuencia cardíaca: banda torácica vs camiseta técnica (Comparison of two methods for recording heart rate telemetry... by Jose Pino Ortega, Alejandro Bastida Castillo, Jose Maria Oliva Lozano, Daniel Rojas Valverde, Pedro Reche Soto, Carlos David Gómez Carmona

“…Heart rate (HR) is one of the most studied and utilized variables for internal load control. Currently, heart rate monitors have been integrated onto sport clothes in order to increase athletes’ comfortability. …”
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“Locality – Adaptation” Research of Hydropower Resettlement Communities in the Jinsha River Basin: A Case Study of Ludila Hydropower Station by Fang WANG, Zhuoqi LI, Haoyi XU, Jiaqi YAN

“…ObjectiveWithin human – environment systems, river basins constitute the earliest geographical units of human activity and currently represent the most critical zones of strained human – environment interactions. …”
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On the added value of sequential deep learning for the upscaling of evapotranspiration by B. Kraft, B. Kraft, B. Kraft, J. A. Nelson, S. Walther, F. Gans, U. Weber, G. Duveiller, M. Reichstein, W. Zhang, M. Rußwurm, D. Tuia, M. Körner, Z. Hamdi, M. Jung

“…However, together with the non-temporal FCN model, they exhibited a larger ensemble spread than XGBoost, and they yielded lower global ET estimates than what is currently understood. XGBoost showed a smaller ensemble spread compared to neural networks, in particular when conditions were poorly represented in the training data, but it was more sensitive to the covariate setup. …”
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Design and Synthesis of Bis-Chalcones as Curcumin Simplified Analogs and Assessment of Their Antiproliferative Activities Against Human Lung Cancer Cells and <i>Trypanosoma cruzi</... by Gabriela Alves de Souza, Lorrane de Souza Chaves, Afonso Santine M. M. Velez, Jorge Lucas F. Lacerda, Paulo Pitasse-Santos, Jayane Clys Conceição dos Santos, Otávio Augusto Chaves, Carlos Serpa, Raphael do Carmo Valente, Leonardo Marques da Fonseca, Marcos André Rodrigues da Costa Santos, Jhenifer Santos dos Reis, Carlos Antônio do Nascimento Santos, Lucia Mendonça-Previato, Jose Osvaldo Previato, Celio Geraldo Freire-de-Lima, Debora Decoté-Ricardo, Leonardo Freire-de-Lima, Marco Edilson Freire de Lima

“…<b>Background: </b>Anticancer therapies represent the primary treatment option for a significant number of cancer patients globally; however, many of these treatments are associated with severe side effects as they target molecular structures present in both cancerous and healthy cells. In a similar context, the treatment of Chagas disease, a neglected tropical illness, is hindered by the high toxicity of the currently available drugs. …”
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Early Warning and Assessment of Chinese Marathon Events' Exposure to High Temperature under Climate Warming by Yu Dandan, Shi Yong, Chen Shuman, Mei Yuru

“…In recent years, the number of marathons in China has expanded rapidly, but the impact of high-temperature weather has become more apparent. Current high-temperature early warning systems lack tailored thresholds and unified standards for sports scenarios. …”
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Regulatory culture and architectural project by Mario Losasso

“…They are attentive to a quality that does not depend on construction solutions or on techno-typological, morphological or physical-chemical characteristics, but which is linked to a system of needs to be satisfied, the outcome of the interaction between construction and cultural, socio-economic and environmental context. Today’s regulatory landscape has expanded, increasing sensitivities to environmental challenges, health and the qualities of living space. …”
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The Structural Model of Happiness Based on Mindfulness with Mediator Role of Emotional Intelligence, Self-Compassion and Resilience by Mohammad Reza Tamannai far, Faezeh Taraffo

“…Moreover, the indirect effect of mindfulness on happiness was significant in that mindfulness leads to an increase in resilience by enhancing emotional intelligence and self-compassion, while it improves happiness by increasing resilience. …”
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Conceptualization of Policies, Strategies and Programs for Poverty Alleviation in Iran: A Qualitative Study by Hassan Danaeefard, Morteza Nabavi, Faramarz Nasri, Seyed Mohammad Javad Sajjadi Nezhad

“…., were created to help alleviate poverty in the country.The Research Center of the Islamic Council has stated in a report that the poverty line rate has been increasing since 2011 and has reached from 19.4% to 30/4% in 2021. …”
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Improving health-promoting workplaces through interdisciplinary approaches. The example of WISEWORK-C, a cluster of five work and health projects within Horizon-Europe by Deborah De Moortel, Michelle C Turner, Ella Arensman, Alex Binh Vinh Duc Nguyen, Víctor Gonzalez

“…New survey shows the mental health of European workers is increasingly at risk. https://www.etui.org/news/new-survey-shows-mental-health-european-workers-increasingly-risk 7. …”
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Anisotropic flexible stress sensors based on Loofah/CN/MWCNTs by 刘璐, 贾晓丽, 黄书童, 张景龙, 李守宝, 柯燎亮

“…Consequently, the loofah skeleton and conductive coating were compressed and released simultaneously, effectively functioning as a variable resistor. As applied stress increased, the loofah framework became more compact, gradually increasing the contact area between carbon-based materials of different sizes, thereby generating new current pathways. …”
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Mineralogy and sulfide mineral chemistry of Khabr iron ore, Southwest of Baft (Southeast of Sanandaj-Sirjan Zone) by Mohammad Boomeri, Habib Biabangard, Somayeh Dehghani Soltani, Azadeh Bordbar

“…Discussion and Results  The iron mineralization occurs at the contact of carbonate rocks and phyllite and schists. …”
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Time to treat the climate and nature crisis as one indivisible global health emergency by Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski

“…Fish provide more than half of dietary protein in many African, South Asian and small island nations, but ocean acidification has reduced the quality and quantity of seafood.16 Changes in land use have forced tens of thousands of species into closer contact, increasing the exchange of pathogens and the emergence of new diseases and pandemics.17 People losing contact with the natural environment and the declining loss in biodiversity have both been linked to increases in non-communicable, autoimmune, and inflammatory diseases and metabolic, allergic and neuropsychiatric disorders.10,18  For Indigenous people, caring for and connecting with nature is especially important for their health.19 Nature has also been an important source of medicines, and thus reduced diversity also constrains the discovery of new medicines. …”
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Group-based interventions to reduce gambling involvement among male football fans: a synopsis of findings from a feasibility study by Gerda Reith, Blair Biggar, Chris Bunn, Manuela Deidda, Craig Donnachie, Frankie Graham, Cindy Gray, Nicola Greenlaw, Kate Hunt, Matthew Philpott, Neil Platt, Robert D Rogers, John Rooksby, Sally Wyke, Heather Wardle

“…Football Fans and Betting was most successful in feasibility delivery when it was delivered within grassroots and local community contexts. Conclusions In the current climate of gambling industry penetration into professional football, promoting a gambling harms prevention intervention proved an insurmountable challenge. …”
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Interpersonal counselling for adolescent depression delivered by youth mental health workers without core professional training: the ICALM feasibility RCT by Jon Wilson, Viktoria Cestaro, Eirini Charami-Roupa, Timothy Clarke, Aoife Dunne, Brioney Gee, Sharon Jarrett, Thando Katangwe-Chigamba, Andrew Laphan, Susie McIvor, Richard Meiser-Stedman, Jamie Murdoch, Thomas Rhodes, Carys Seeley, Lee Shepstone, David Turner, Paul Wilkinson

“…However, alterations to the referral pathways did not increase the number of referrals made to the study. …”
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Territories -in- between by Alexander Wandl

“… There is an increasing body of literature suggesting that the conventional idea of a gradual transition in spatial structure from urban to rural does not properly reflect contemporary patterns of urban development and their potential for sustainable development. …”
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Supporting antiretroviral therapy uptake and adherence: the SUPA research programme and RCT by Rob Horne, Caroline Sabin, Trudie Chalder, Vanessa Cooper, Lucy Campbell, Elizabeth Glendinning, Iris Mosweu, Paul McCrone

“…In the United Kingdom, the uptake of antiretroviral therapy is generally high, but a delay in starting antiretroviral therapy and non-adherence compromise the health and well-being of people living with human immunodeficiency virus, increase the risk of transmission of human immunodeficiency virus and increase National Health Service costs. …”
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Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…Men were excluded if they were unable to pass urine without a catheter, had a relevant neurological disease, were currently undergoing treatment for prostate or bladder cancer, had previous prostate surgery or were unfit for surgery. …”
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