miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

“…Conversely, inhibiting miR-34a-5p resulted in an increase in cell growth and a decrease in programmed cell death. …”
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Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

“…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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Meta-analysis on the effects of chemical stressors on freshwater ecosystem functions by Alexander Feckler, Ralf Schulz, Ralf B. Schäfer

“…Importantly, the shape and direction of the relationships identified here match those reported in field-based studies, indicating a decrease in functioning as chemical stress increases, strengthening the ecological relevance of our findings. …”
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The implementation of Safety Management Systems in healthcare: a systematic review and international comparison by Zhivko Zhelev, Sian de Bell, Alison Bethel, Maria Clarke, Rob Anderson, Jo Thompson Coon

“…Approaches to patient safety in all countries reflect increasing awareness that for an initiative to be successful, it needs to be context-specific. …”
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Two decades of cropland monitoring in Changsha-Zhuzhou-Xiangtan city group: trends and future predictions by Wenbo Zhang, Dazhao Fan, Song Ji, Yang Dong, Dongzi Li, Ming Li

“…The results demonstrated that the cropland area in the CZTCG in the past 20 years has shown a two-stage trend of increasing (2000–2015, increase of 8.25%) and decreasing (2015–2020, decrease of 2.91%), and the main reasons for cropland loss in the whole process of change were forest and building, with serious loss of cropland area in Changsha County and Wangcheng District. …”
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Application of Jane Jacobs’ Theory in the Analysis of the Borders of Territory Monitoring in Urban Spaces from Citizens’ Points of View in Bandar Abbas by Amirhamzeh Shahbazi, Esmaeil zakerimnabi, Alireza Shahbazi

“…The inclination to monitor such spaces decreased after age 40, reaching zero among those over 70. …”
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A virus becomes a global concern: research activities on West-Nile virus by Doris Klingelhöfer, Markus Braun, Isabelle M. Kramer, Friederike Reuss, Ruth Müller, David A. Groneberg, Dörthe Brüggmann

“…Currently, West-Nile virus (WNV) is spreading worldwide to colder regions due to climate change. …”
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Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

“…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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高敏感特質中高齡學習者面對數位學習壓力及疫情焦慮之學習滿意度與後疫情調適：復原力之中介效果 Learning Satisfaction and Post-Pandemic Adaptation in Highly Sensitive Middle-aged and Elderly Learners in the Face of Digital Learni... by 王雅鈴 Ya-Ling Wang, 張伶瑜 Lin-Yu Chang, 羅淇文 Chi-Wen Luo, 林郁文 Yu-Wen Lin

“…This study aims to investigate the relationship between digital learning stress, pandemic anxiety, depression, learning satisfaction and post-pandemic experiences in highly sensitive middle-aged and elderly learners in the context of the widespread adoption of digital learning due to the pandemic, and explore the role of resilience as a mediating variable. …”
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Presentation of Financial Assets in the Statistics of Foreign Economic Relations by V. N. Salin, L. Yu. Arhangelskaya, O. G. Tretyakova

“…Together with the financial account, account figures for other changes in financial assets and liabilities explain the total amount of changes: increases or decreases in the value of financial assets / liabilities, their occurrence or disposal, resulting from transactions, revaluation and other changes in volume.The issues of theory and practice of presenting indexes of financial assets in the considered sections of macrostatistics and their analysis are a relevant and promising direction for improving national statistical accounting, incl. due to the spread of remote work, the collection of information via the Internet, the emergence of a large number of new financial instruments and operations.The authors of the article have repeatedly referred to the problems of macroeconomic financial statistics in their studies, which gave them the opportunity to comprehensively consider the topical issues of representing financial assets in the statistics of foreign economic relations.…”
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Coordinated regulation of timing and strength of synaptic outputs by adrenergic receptors through control of action potentials in Purkinje cells by Kei Furukawa, Kei Furukawa, Shin-ya Kawaguchi

“…We demonstrate that Purkinje cell axons exhibit negative control of action potentials in amplitude and conduction velocity by β-adrenergic receptors in a manner dependent on the axonal length through specific reduction of axonal Na+ currents. On the other hand, β-adrenergic receptors increased presynaptic release probability without changing the amount of readily releasable vesicles in axon terminals of Purkinje cells. …”
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Reassessing immediate coal phase-out: Dual imperatives of capacity control and renewables expansion in China’s net-zero strategy by Jiaxing Wang, Xi Lu, Hao Wang, Yang Ou, Jianxiao Wang, Dan Tong, Yan Li, Ziwen Ruan, Zihua Yin, Wenlong Zhou, Benjamin McLellan, Emily Xing, Anna M. MacLennan, Jingli Fan, Xian Zhang, Michael B. McElroy, Kebin He

“…Broader context: Reducing CO2 emissions in power systems is crucial for China in achieving its net-zero emission target. …”
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Cervical ripening at home or in hospital during induction of labour: the CHOICE prospective cohort study, process evaluation and economic analysis by Mairead Black, Cassandra Yuill, Mairi Harkness, Sayem Ahmed, Linda Williams, Kathleen A Boyd, Maggie Reid, Amar Bhide, Neelam Heera, Jane Huddleston, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Gordon C S Smith, Rosemary Townsend, Helen Cheyne, Christine McCourt, Sarah Stock

“…However, there was substantial uncertainty with the adjusted analysis consistent with a 74% decrease in the risk through to an 81% increase. qCHOICE Important aspects of service users’ experience of home cervical ripening were quality of information provided, support and perception of genuine choice. …”
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Making temporary homes by Marjolein Overtoom

“…Decreasing the housing shortage by building new houses takes time, while people need to find a space to live now. …”
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Improving outcomes for people with autism spectrum disorders by reducing mental health problems: the IAMHealth research programme including one RCT by Emily Simonoff, Gillian Baird, Bryony Beresford, Tony Charman, Martin Knapp, Andrew Pickles, Carol Povey, Tom Purser, Paramala Santosh, Vicky Slonims, Stephen Scott

“…Factors contributing to this included beliefs about the causes of MHP and increased vulnerability with the context of a diagnosis of autism, knowledge of self-management and, based on prior experiences, a view that professional support or intervention was unavailable or inadequate. …”
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Impact of frailty in older people on health care demand: simulation modelling of population dynamics to inform service planning by Bronagh Walsh, Carole Fogg, Tracey England, Sally Brailsford, Paul Roderick, Scott Harris, Simon Fraser, Andrew Clegg, Simon de Lusignan, Shihua Zhu, Francesca Lambert, Abigail Barkham, Harnish Patel, Vivienne Windle

“…Prescriptions increased with increasing age in both Fit and Mild frailty categories but decreased in moderate and severe categories. …”
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Matrix Gla Protein – a new marker for colorectal cancer detection? A systematic review by Mirela-Georgiana Perné, Lorena Ciumărnean, Olga-Hilda Orășan, Vasile Negrean, Teodora-Gabriela Alexescu, Mircea Vasile Milaciu, Ioana Roșca, Răzvan Dan Togănel, Gabriel Emil Petre, Lucia Procopcoiuc, Cristina Drugan, Alexandra Crăciun

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SOUTH AFRICAN USERS’ FUNCTION AND EXPERIENCE WITH A MAGNETORHEOLOGICAL MICROPROCESSOR KNEE: A MIXED METHODS STUDY by Surona Visagie, Benje Theron

“…CONCLUSION: This study provides context specific scientific evidence that may support funding decisions for MPKs in South Africa. …”
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DEVELOPMENT PROSPECTS OF THE RUSSIAN MARKET OF TECHNICAL SERVICING AND REPAIR IN THE СONTEXT OF A PANDEMIC by O. A. Tettsoeva

“…Currently, at a time of decreasing automotive production caused by the suspension of the plants in the period of lockdown, the reduction in purchasing power of communities connected with the risk of unemployment occurrence in consequence of business failures, the decline in wages and lower vacancy rates, is foreseen reduced demand for new cars against the background of significant increase in sales volumes in the used cars market segment and, therefore, sharp increase in demand for car services performing technical servicing and repair. …”
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