Scientific and Regulatory Lessons Learnt on Building a Chemistry, Manufacturing, and Controls (CMC) Package for COVID-19 Variant Vaccine Updates in the EU—A Regulator’s Perspective... by Ragini Shivji, Elena Grabski, Veronika Jekerle

“…The pace at which variants emerge challenges the technical feasibility to make adapted vaccines available in a suitable timeframe and in sufficient quantities. Despite the current absence of a clear-cut seasonal spread for COVID-19, the EU regulatory approach thus far is a pragmatic approach following a pathway similar to that of seasonal influenza. …”
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Phylogenetic Groups and Antimicrobial Resistance among Uropathogenic Escherichia coli Isolates from Hospitalized Patients in Tehran by Mana Talebi Farahani, Mohammad Karim Rahimi, Mehdi Goudarzi

“…Background: The presence of Escherichia coli among uropathogens is increasing significantly worldwide. It accounts for a considerable amount of morbidity and high medical costs and also can lead to mortality. …”
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N-Acetyl-cysteine and Mechanisms Involved in Resolution of Chronic Wound Biofilm by Xin Li, Jane Kim, Jiabin Wu, Alaa’ I Ahamed, Yinsheng Wang, Manuela Martins-Green

“…Chronic wounds are a major global health problem with the presence of biofilm significantly contributing to wound chronicity. Current treatments are ineffective in resolving biofilm and simultaneously killing the bacteria; therefore, effective biofilm-resolving drugs are needed. …”
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Non-linear oral bioavailability and clinical pharmacokinetics of high-dose Andrographis paniculata ethanolic extract: relevant dosage implications for COVID-19 treatment by Phanit Songvut, Jaratluck Akanimanee, Tawit Suriyo, Nanthanit Pholphana, Nuchanart Rangkadilok, Duangchit Panomvana, Porranee Puranajoti, Jutamaad Satayavivad

“…These findings suggest that current extraction process of ethanolic extract may hinder its effectiveness. …”
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Stability and change in latent movement behaviour profiles during adolescence and links with future depressive symptoms by Christopher Knowles, Gavin Breslin, Angela Carlin, Kyle Paradis, Stephen Shannon

“…Transition patterns containing a period of minimal movement predicted worse depressive symptoms at ages 18 and 22. …”
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Copper homeostasis and neurodegenerative diseases by Yuanyuan Wang, Daidi Li, Kaifei Xu, Guoqing Wang, Feng Zhang

“…Copper is a potent oxidant that increases reactive oxygen species production and promotes oxidative stress. …”
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TIM-3 teams up with PD-1 in cancer immunotherapy: mechanisms and perspectives by Zhuohong Yan, Chunmao Wang, Jinghong Wu, Jinghui Wang, Teng Ma

“…Among these candidates, T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is considered a promising target. …”
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Spatio-temporal changes of water quality variables in a highly disturbed river by Z. Abdollahi, A. Kavian, S.H.R. Sadeghi

“…Many rivers in developing countries are unhealthy because they contain harmful physical, chemical and biological agents. …”
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Descriptive, analytical and molecular epidemiology of pancreatic cancer by O. V. Shangina, D. M. Maximovich, D. G. Zaridze

“…The purpose of the study was to present current data on the role of lifestyle and heredity factors in the etiology of pancreatic cancer (PC). …”
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Identification of widely conserved biosynthetic gene cluster involved in pigment production of Bacillus subtilis by Rune Overlund Stannius, Christopher A. Dunlap, Estelle Morvan, Mélanie Berbon, Sophie Lecomte, Antoine Loquet, Ákos T. Kovács

“…This study describes the chemical and biological features of a new class of SM BGC, which we hope will serve to improve the current BGC discovery pipelines in Bacilli.IMPORTANCEIdentification of novel microbial secondary metabolites (SMs) and their biosynthetic gene cluster (BGC) has become increasingly difficult, especially in Bacilli, as the tools for screening and genome mining are dependent on clear function or similarity to already known BGCs. …”
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3D-printed resin for permanent/definitive restorations: meta-analysis for bond strength by Minjoo Ki, Marc Hayashi, Mijoo Kim

“…Background Three-dimensional (3D) printing technologies have gained increasing popularity in restorative dentistry for fabricating polymer-based restorations. …”
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Marketing Logistics and its Digitalization by Iryna Polishchuk, Yuriy Dovhan, Iryna Kramar, Larysa Dovhan, Oksana Yakushevska

“…The purpose of the article is to highlight the historical process of forming marketing logistics as a modern management concept and the current trends in its digitalization. The theoretical foundations of marketing logistics summarized in this work will facilitate the integration of digital technologies into marketing logistics, improve business processes, and support the sustainable development of companies in the context of dynamic changes in the global market. …”
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The Direction of Indonesia’s Legal Policy on the ASEAN Mutual Legal Assistance Treaty in Criminal Matters: A Path to Law Reform in Cross-Border Crime Enforcement in Southeast Asia... by Ridwan Arifin, Rodiyah Rodiyah, Waspiah Waspiah, Asyaffa Ridzqi Amandha, Elizabeth Yunita Krisnawati, Tirta Sandi, Michael Timothy Napitupulu

“…First, it provides a comprehensive analysis of the current state of Indonesia’s legal policy on AMLAT, highlighting key areas for legal reform. …”
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Study of Ionanofluids Behavior in PVT Solar Collectors: Determination of Thermal Fields and Characteristic Length by Means of HEATT^® Platform by Mariano Alarcón, Juan-Pedro Luna-Abad, Manuel Seco-Nicolás, Imane Moulefera, Gloria Víllora

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A Systematic Review Examining the Association of Falls With Diabetes‐Related Foot Ulcers by Mike Wu, Mallika Sinha, Chanika Alahakoon, Kristen S. Barratt, Shivshankar Thanigaimani, Jonathan Golledge

“…A meta‐analysis showed high heterogeneity between studies (I2 = 95%) and an increased risk of falls in people with DFU (risk ratio 2.25 and 95% CI 1.05–4.84). …”
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Optimal Decision-Making in a Green Supply Chain Duopoly: A Comparative Analysis of Subsidy Strategies with Data-Driven Marketing by Yao Yao, Shaoqing Geng, Jianhui Chen, Feng Shen, Huajun Tang

“…In the current context of severe environmental challenges and climate change, the low-carbon green development model has become an international consensus. …”
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No decision about me, without me: Collaborating with young people in mental health research by Alex Lloyd, Tom (Chin‐Han) Wu, Laura Lucas, Adeola Agunbiade, Romana Saleh, Pasco Fearon, Essi Viding

“…In recognition of the value of collaborating with experts by experience, international funders are increasingly mandating that mental health research is developed by teams that include individuals from the population of study. …”
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Eating- and Weight-Related Disorders in the Armed Forces by Hubertus Himmerich, Davide Gravina, Inga Schalinski, Gerd-Dieter Willmund, Peter Lutz Zimmermann, Johanna Louise Keeler, Janet Treasure

“…Conclusions: Even though randomized controlled trials (RCTs) have been performed to test treatments for obesity in the armed forces, RCTs for the treatment of EDs, body dysmorphic disorder, muscle dysmorphia, and RED-S syndrome are lacking in the military context.…”
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Hybrid Energy Solutions for Enhancing Rural Power Reliability in the Spanish Municipality of Aras de los Olmos by Pooriya Motevakel, Carlos Roldán-Blay, Carlos Roldán-Porta, Guillermo Escrivá-Escrivá, Daniel Dasí-Crespo

“…As global energy demand increases, ensuring a reliable electricity supply in rural or semi-remote areas remains a significant challenge. …”
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Peas (<i>Pisum sativum</i> subsp. <i>arvense</i> Asch) and Beans (<i>Vicia faba</i> var. <i>minor</i>) as Source of Quality Plant Proteins by Abebaw Tiruneh, Paweł Ptaszek, Daniel Żmudziński, Tomasz Tarko

“…Consequently, plant proteins are increasingly favored over their animal-based counterparts in the food industry. …”
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