Bone marrow mesenchymal stem cell-derived exosomes alleviate DSS-induced inflammatory bowel disease in mice through inhibiting intestinal epithelial cell pyroptosis via delivery of... by Bihua Wu, Shuangyan Su, Xianyu Wang, Yuwei Li, Zhenghao Mei, Fenglin Lou, Le Guo

“…BackgroundInflammatory bowel disease (IBD), characterized by chronic intestinal inflammation and epithelial barrier dysfunction, remains a therapeutic challenge due to the limitations of current treatments, including drug resistance and invasive surgical risks. …”
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Optimizing in vitro slow-growth conservation media for garlic under ambient conditions: further implications for core set accessions by Ashwini Prashant Benke, DalasanuruChandregowda ManjunathaGowda, Vijay Mahajan, Digambar N. Mokat

“…Therefore, maintaining the crop’s genetic diversity in a suitable alternative form is crucial. The current study standardized the protocol for slow-growth conservation of garlic (in vitro) at an ambient temperature. …”
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Finerenone attenuates downregulation of the kidney GLP-1 receptor and glucagon receptor and cardiac GIP receptor in mice with comorbid diabetes by Duc Tin Tran, Emily S. H. Yeung, Lisa Y. Q. Hong, Harmandeep Kaur, Suzanne L. Advani, Youan Liu, Madiha Zahra Syeda, Sri Nagarjun Batchu, Andrew Advani

“…After 26 weeks, mice were fed a high fat diet containing finerenone (100 mg/kg diet) or high fat diet alone for a further 2 weeks. …”
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Effects of dietary myo-inositol on growth performance, hematological parameters, antioxidant capacity, immunity and resistance against Aeromonas hydrophila in red swamp crayfish (P... by Guoliang Ruan, Heng Zhang, Wei Chen, Liu Fang, Jiu Shu, Qian Wang

“…Myo-inositol (MI) as a vitamin-like nutrient has not been investigated in P. clarkii yet, current study was made to investigate the effect of dietary MI on the growth and health of the crayfish, P. clarkii (8.05 ± 0.71 g) fed with diets containing 0 (M0), 800 (M1), 1600 (M2), 2400 (M3), and 3200 (M4) mg/kg of MI for eight weeks. …”
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Combining the RCAS/tv-a retrovirus and CRISPR/Cas9 gene editing systems to generate primary mouse models of diffuse midline glioma by Sophie R. Wu, Julianne Sharpe, Joshua Tolliver, Abigail J. Groth, Reid Chen, María E. Guerra García, Vennesa Valentine, Nerissa T. Williams, Sheeba Jacob, Zachary J. Reitman

“…Genetically engineered mouse models (GEMMs) are critical to studying tumorigenesis and tumor-immune interactions, which may inform new treatment approaches. However, current midline glioma GEMM approaches are limited in their ability to multiplex perturbations and/or target specific cell lineages in the brain for genetic manipulation. …”
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The attenuated African swine fever vaccine HLJ/18-7GD provides protection against emerging prevalent genotype II variants in China by Zilong Wang, Jiwen Zhang, Fang Li, Zhenjiang Zhang, Weiye Chen, Xianfeng Zhang, Encheng Sun, Yuanmao Zhu, Renqiang Liu, Xijun He, Zhigao Bu, Dongming Zhao

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An animal model study of simplified optical navigation system-assisted percutaneous lumbar transforaminal puncture by B. N. Wenxiu Chai, Yuqing Chen, Li Sheng, Yong Huang

“…The system significantly improves puncture accuracy while markedly decreasing both the number of puncture attempts and fluoroscopy exposures compared to conventional techniques.…”
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Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…Men were excluded if they were unable to pass urine without a catheter, had a relevant neurological disease, were currently undergoing treatment for prostate or bladder cancer, had previous prostate surgery or were unfit for surgery. …”
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Urodynamics tests for the diagnosis and management of male bladder outlet obstruction: long-term follow-up of the UPSTREAM non-inferiority RCT by Madeleine Clout, Amanda L Lewis, Madeleine Cochrane, Grace J Young, Paul Abrams, Peter S Blair, Christopher Chapple, Gordon T Taylor, Sian Noble, Tom Steuart-Feilding, Jodi Taylor, J Athene Lane, Marcus J Drake

“…Men were excluded if they were unable to pass urine without a catheter, had a relevant neurological disease, were currently undergoing treatment for prostate or bladder cancer, had previous prostate surgery or were unfit for surgery. …”
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Gene Editing Anxiety by Angelo Osofsky

“…Health and Genetic Risks of Germline Editing Editing the human germline to prevent psychiatric disorders poses serious health risks to individuals. Currently, scientists warn that genetically altering the human genome can result in off-target mutations that increase the risk of disease. …”
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Catalogue of bat viruses (2020) by M. Yu. Shchelkanov, M. N. Dunaeva, T. V. Moskvina, A. N. Voronova, Yu. V. Kononova, V. V. Vorobyeva, I. V. Galkina, V. A. Yanovich, A. A. Gadzhiev, A. M. Shestopalov

“…Aim of this the research presented in this article is to analyze the representation of bat (Chiroptera) viruses in various taxa of the Virae kingdom.Discussion. Currently, 260 viruses are associated with bats belonging to 19 orders, 28 families (9 DNA‐containing and 19 RNA‐containing) and 61 genera (18 DNA‐containing and 43 RNA‐containing). …”
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Social Networks Link Prediction Based on Incremental Learning by Jian SHU, Zhichen CHEN

“…However, the prediction performance of IL−SNLP on Ask Ubuntu and Super User decreases by only 4.54% and 5.25%, respectively, compared to its performance on Math Overflow. …”
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Chalcogenides in Perovskite Solar Cells with a Carbon Electrode: State of the Art and Future Prospects by Maria Bidikoudi, Elias Stathatos

“…Perovskite solar cells (PSCs) have been on the forefront of advanced research for over a decade, achieving constantly increasing power conversion efficiencies (PCEs), while their route towards commercialization is currently under intensive progress. …”
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SIGNIFICANCE OF THE PORT OF SINGAPORE AGAINST THE COUNTRY’S ECONOMIC GROWTH by Maciej MINDUR

“…This research covers the port’s ownership and organisational structure, and its terminals have been reviewed in terms of their location, infrastructure and functions by taking into account the new generation terminal of the port of Tuas, currently under development. Over the years, the port has seen a steady increase in revenue from transhipment, which is confirmed by the dynamics of the container volume growth over the years 1972–2017, the transhipment volume over the years 2007–2018 and the number of container ships calling at the port along with their total capacity over the years 2007–2017, as elaborated in the article.…”
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THE THERMAL STABILITY OF POLYMER CABLE COMPOUNDS WITH A FLAME-RETARDING FILLER by A. Yu. Svatikov, I. D. Simonov-Emelyanov

“…Currently, halogen-free cable compositions are becoming increasingly common in the manufacture of cable compositions. …”
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Antimicrobial resistance: Past, present, and way forward by Ramashankar Rath, Pradip Kharya, Aroop Mohanty, Anil R. Koparkar, Anand M. Dixit, Hari Shanker Joshi, Vivek Hada

“…A containment plan is currently being executed but yet to achieve the full extent as intended. …”
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Development of standard samples-simulators of weight fraction of acetone insoluble substances in rapeseed lecithins by O. S. Agafonov, E. V. Lisovaya, S. M. Prudnikov, E. P. Victorova

“…Currently, there is an increase in the volume of rapeseed processing, which leads to a natural increase in the production of by-products such as rapeseed lecithin. …”
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Characterization of harmful gases and bioaerosols of pig farms: a review of the existing literature by P. B. Grigorash, Y. V. Horiuk

“…The existing strategies and methods to combat these problems are still imperfect and need to be refined. Currently, the interaction of harmful gases, dust, solid particles and microorganisms is not taken into account, which can increase the toxic effect of each other on the animal's body. …”
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COST531 project: Study of the advanced materials for lead free soldering by Kroupa A., Dinsdale A.T., Watson A., Vrestal J., Zemanova A.

“…The main aim was to increase the basic knowledge on possible alloy systems that were used or planned to be used as lead-free solder materials and offer scientific information about these materials in order to replace the currently used lead-containing solders. …”
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Accelerated weathering of PP based nanocomposites: Effect of the presence of maleic anhydryde grafted polypropylene by N. Tz. Dintcheva, M. Morreale, F. P. La Mantia

“…Polymer nanocomposites are currently a topic of great interest. The increasing importance they are gaining also in the standpoint of industrial applications, is giving concerns regarding their environmental stability and, in general, their behaviour in outdoor applications, under direct solar irradiation. …”
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