Topical Application of RNAi Therapy Using Surface-Modified Liposomes for Treating Retinal-Vein Occlusion by Taishi Shiratori, Takaaki Ito, Anri Nishinaka, Ryosuke Matsumiya, Eriko Yamazoe, Hirofumi Takeuchi, Hideaki Hara, Kohei Tahara

“…Recently, antibody- and nucleic acid-based pharmaceuticals have increasingly been used to treat retinal diseases, with improvement or cure as the goal; however, these drugs are currently only administered by intravitreal injection. …”
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The role of judicial authorities in criminal proceedings for political crimes in the Stalinist period: modern historiography by Alexander Ya. Kodintsev

“…Currently, PhD theses, covering an increasing number of regions of Russia, are being defended actively. …”
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A methionine/aspartate-rich synthetic peptide delineated from N-terminal region of nucleophosmin protein effectively protects against cadmium-induced toxicity by Rui Yan, Heng Wee Tan, Xiao-Yun Zhao, Jia-Yi Wu, Qiu-Hua Zhong, Xiu-Yun Wang, Na-Li Cai, Yan-Ming Xu, Andy T.Y. Lau

“…The molecular mechanism of Cd cytotoxicity is complicated and still not well understood, and treatment options for Cd cytotoxicity are lacking. Currently, only a limited number of Cd-targeted proteins have been identified. …”
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Identifying studies evaluating susceptibility factors for chemical health assessments: A case study focused on methylmercury developmental neurotoxicity by Deborah Segal, Rebecca Nachman, Onyemaechi Nweke, Elizabeth Radke, Geanine Brunson, Bita Khoshhal, G. Nicole Helguero, Leonid Kopylev

“…However, at this time, Approach 1, involving the application of a dose–response filter, is currently recommended for identifying epidemiology papers with information on susceptibility factors.…”
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Social sensing a volcanic eruption: application to Kīlauea, 2018 by J. Hickey, J. Young, M. Spruce, M. Spruce, R. Pandit, R. Pandit, H. Williams, R. Arthur, W. Stovall, M. Head

“…Here we use social sensing of Twitter (currently known as X) posts to track changes in social action and reaction throughout the 2018 eruption of Kīlauea on the island of Hawai`i. …”
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Military and political security in the Arctic before and amidst the Ukrainian crisis by I. A. Arzhanov

“…This course has been reflected in a whole series of alliance’s military exercises, which, as shown in the article, are becoming increasingly extensive and regular year by year. The author concludes that the Ukrainian crisis has only laid bare the true aspirations of the NATO countries seeking to contain Russia in the Far North and refusing to consider its interests and build a constructive dialogue in the field of military and political security. …”
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UML/OCL based design and the transition towards temporal object relational database with bitemporal data by Soumiya Ain El Hayat, Fouad Toufik, Mohamed Bahaj

“…In software modeling, UML (Unified modeling language) receives increasing attention from designers of real-time systems in software development. …”
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Improvement of RT-DETR model for ground glass pulmonary nodule detection. by Siyuan Tang, Qiangqiang Bao, Qingyu Ji, Tong Wang, Naiyu Wang, Min Yang, Yu Gu, Jinliang Zhao, Yuhan Qu, Siriguleng Wang

“…Currently, pulmonary nodules detection work mostly focus on recognition and diagnosis of solid nodules. …”
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Melt‐Processable and Electrospinnable Shape‐Memory Hydrogels by Turdimuhammad Abdullah, Cagatay Altınkok, Oguz Okay

“…Abstract Due to their ability to adapt to subtle changes in response to various external and internal stimuli, smart hydrogels have become increasingly popular in research and industry. However, many currently available hydrogels suffer from poor processability and inferior mechanical properties. …”
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Investigation of hydrogen embrittlement in steel alloys: mechanism, factors, advanced methods and materials, applications, challenges, and future directions: A review by Umme Javeria, Sung Jin Kim

“…Hydrogen embrittlement (HE) remains a critical challenge in structural metals, particularly steels, compromising their mechanical integrity in hydrogen-containing environments. The process typically initiates with crack nucleation and progresses to fracture due to a reduction in ductility and an increase in brittleness. …”
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T cell epitope content comparison using EpiCC correlates with vaccine efficacy against heterologous porcine reproductive and respiratory syndrome virus type 2 strains by J. Mark Hammer, Andres H. Gutierrez, Lucas Huntimer, Benjamin Gabriel, William D. Martin, Sabine E. Hammer, Tobias Käser, Anne S. De Groot

“…While vaccines are available, they are not entirely effective, and the introduction of modified live virus vaccines (MLV) has contributed to an increase in the rate of viral evolution. While vaccines induce humoral responses that may contribute to immunity against PRRSV, vaccines containing T cell epitopes that are well-matched to circulating strains are believed to be more likely to induce protective effects upon challenge or field exposure. …”
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Evaluation of intestinal tissue safety during the compression process of circular end-to-end anastomosis stapler based on finite element simulation by Yuanda Zhou, Yuanda Zhou, Yuanda Zhou, Yuanda Zhou, Zhen Tan, Peishi Jiang, Yi Sun, Yi Sun, Yi Sun, Yi Sun, Dewang Wu

“…ObjectiveCurrently, there is no standardized finite element analysis method for investigating the safe compression range of circular end-to-end anastomosis stapler. …”
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Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes. by Sharon E Robertson, Maya Yasukawa, Douglas C Marchion, Yin Xiong, Syeda Mahrukh Hussnain Naqvi, Tarik Gheit, Massimo Tommasino, Robert M Wenham, Anna R Giuliano, Johnathan M Lancaster, Mian M K Shahzad

“…<h4>Introduction</h4>Currently 11 infectious agents are classified as carcinogenic but the role of infectious agents on outcomes of epithelial ovarian cancer is largely unknown.…”
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Mapping the global distribution and conservation status of oases—ecosystems of pivotal biocultural relevance by Juan Antonio Hernández-Agüero, Mechthilde Falkenhahn, Jessica Hetzer, Karsten Wesche, Christiane Zarfl, Klement Tockner

“…However, less than 0.5% of their total area is currently under protection, making oases one of the least conserved ecosystems worldwide. …”
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Cybercrime as a New Object of Statistical Analysis by A. E. Lyapin

“…The real damage from cybercrimes is currently difficult to calculate, while the number of these crimes is growing rapidly from year to year. …”
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Direct and Indirect Methods for Studying Human Gut Microbiota by V. T. Ivashkin, O. S. Medvedev, E. A. Poluektova, A. V. Kudryavtseva, I. R. Bakhtogarimov, A. E. Karchevskaya

“…Aim: To review the main methods of intestinal microbiota studying.Key points. Currently, molecular genetic methods are used mainly for basic research and do not have a unified protocol for data analysis, which makes it difficult to implement them in clinical practice. …”
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Multi-contrast machine learning improves schistosomiasis diagnostic performance. by María Díaz de León Derby, Charles B Delahunt, Ethan Spencer, Jean T Coulibaly, Kigbafori D Silué, Isaac I Bogoch, Anne-Laure Le Ny, Daniel A Fletcher

“…Schistosomiasis currently affects over 250 million people and remains a public health burden despite ongoing global control efforts. …”
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development of the Scientific School of the financial university in the field of accounting-analytical and control Systems in the Modern Economy by R. P. Bulyga, M. V. Melnik

“…The following areas of research have been identified as key issues of updating and adapting the school to the modern stage of economic development: improving the methodology and methodology for developing reporting of economic entities, taking into account changes in their organizational structures (corporate reporting), including consolidated reporting, reporting in the format of sustainable development, containing a wide range of non-financial information (ESG agenda) and integrated reporting, as well as strengthening the role of internal (production, management) control, based on new opportunities, information and communication systems; the formation of internal and external control and audit systems of various directions, facilitating reliable feedback between production and management bodies; strengthening and developing the interaction of accounting systems (accounting, operational production, statistical) of all levels to create on this basis high-quality databases for information support of management; increasing the efficiency of all parts of the national economy and implementing the strategy for the development of the economy of the country, regions and industries. …”
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Analysis of a segmentation approach to breeder blanket design and the utilisation of FLiBe as a novel neutron reflector by Adam J. Barker, Mark R. Gilbert, Philip D. Edmondson

“…Tritium is a rare resource, currently produced only in a limited number of fission reactors and other low-output facilities. …”
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Microvesicles produced by natural killer cells of the NK-92 cell line affect the phenotype and functions of endothelial cells of the EA.Hy926 cell line by K. L. Markova, V. A. Mikhailova, A. V. Korenevsky, Yu. P. Milyutina, V. V. Rodygina, E. P. Aleksandrova, A. S. Markov, O. A. Balabas, S. A. Selkov, D. I. Sokolov

“…The results revealed significant differences in the proteomic profiles of cells of the NK-92 cell line and their MV product. Contact between ECs and MVs derived from cells of the NK-92 cell line is accompanied by the following events: a) expression of granzyme B in ECs, b) activation of caspase-9 and caspase-3, with partial EC death, c) appearance of the panleukocyte marker CD45 on ECs, d) decrease in CD105 expression, and increase in CD34 and CD54 expression, and e) inhibition of EC migration. …”
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