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Approaches to clinical development of combination medicines in the Russian Federation and the Eurasian Economic Union in view of the requirements of the current legislation
Published 2019-03-01“…In recent years, there has been an increasing interest in the development of combination medicines (fixed drug combinations) containing two or more active ingredients in a single dosage form. …”
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An Increased Plasma D-Dimer Levels During Different Stages of Normal and Complicated Pregnancies Among Women in Bisha, Saudi Arabia
Published 2025-08-01“…These findings underscore the importance of interpreting D-dimer values in the context of gestational age and pregnancy complications. …”
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An analysis of the Policy of Increasing the Salaries of Government Employees Based on the Framework of Kingdon's Multiple Streams (Case Study of Budget Law 1401)
Published 2024-09-01“…The current research aims to analyze the policy of increasing government employees' salaries within the framework of Kingdon's multiple streams model in the context of the 1401 budget law. …”
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Main factors influencing the digital economy: a literature review
Published 2024-12-01“…In response to the challenges of our time, our research aims to understand and analyse the trends of digitalization of the economy in the current context. It is important to note that this topic is becoming increasingly relevant in the context of the rapid development of technology and its impact on the global economy as a whole. …”
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MicroRNA-32-5p inhibits metastasis by directly targeting VPS4B and increases sensitivity to dihydroartemisinin in neuroblastoma
Published 2024-09-01“…The primary objective of the current investigation was to characterize a newly discovered microRNA, miR-32-5p, in terms of the functional role, underlying mechanism of action, and potential synergistic therapeutic impact in the context of NB metastasis. …”
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A Dynamic Interval Auto-Scaling Optimization Method Based on Informer Time Series Prediction
Published 2025-01-01“…Currently, widely used responsive auto-scaling methods, such as Kubernetes HPA, exhibit certain lags due to the startup time costs of containers and Pods. …”
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Frequency of weight and body composition increases in advanced non‐small cell lung cancer patients during first line therapy
Published 2024-12-01“…One cohort received the current standard of care (CSOC), which consisted of immunotherapy and newer chemotherapy regimens, and the other cohort was treated with the former standard of care (FSOC), consisting only of older platinum‐containing regimens. …”
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Significantly Increased Aqueous Solubility of Piperine via Nanoparticle Formulation Serves as the Most Critical Factor for Its Brain Uptake Enhancement
Published 2025-03-01“…The PIP NPs could significantly increase the aqueous solubility of piperine from 0.04 mg/mL to 52.31± 0.9 mg/mL and release piperine with a 12.83-fold higher rate than that from piperine suspension. …”
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Study on the Electrochemical Corrosion Resistance Behavior of 20 and L245NS Steels in Simulated Low Sulfur - Containing and CO<sub>2</sub> - Saturated Oilfield Sewage
Published 2021-05-01“…Results showed that corrosion current density of 20 and L245NS steels decreased and charge transfer resistance increased in low sulfur conditions compared to those in sulfur - free conditions. …”
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Effect of Current Density on Structure and Hardness of the MAO Film on 7N01 Aluminum Alloy Surface for Water Pump
Published 2021-07-01“…The hardness of the MAO film prepared with the current density of 1 A/dm2 was 158.3 HV. When the current density increased, the hardness of the film was also improved. …”
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Chaperonin containing TCP1 subunit 6A may activate Notch and Wnt pathways to facilitate the malignant behaviors and cancer stemness in oral squamous cell carcinoma
Published 2024-12-01“…In SCC-15 and HSC-3 cells, CCT6A overexpression increased cell proliferation, invasion, sphere formation, CD133, and Sox2 expression, but decreased cell apoptosis; on the contrary, CCT6A knockout exhibited an opposite effect on the above indexes. …”
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Bioconvective MHD flow of hybrid alumina-silver-water nanofluid across a moving needle containing gyrotactic microorganisms with Cattaneo-Christov heat and mass flux model
Published 2025-06-01“…The current study contains a steady laminar bioconvective magnetohydrodynamic (MHD) flow involving water (H2O)-based hybrid nanofluid composed of silver (Ag) and alumina oxide (Al2O3) as nanoparticles. …”
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Expert opinion on the current conceptual, clinical and therapeutic aspects of disease related malnutrition and muscle loss: a multidisciplinary perspective
Published 2025-07-01“…Therefore, the proposed expert opinion aimed to address the current conceptual, clinical and therapeutic aspects of DRM and muscle loss from a multidisciplinary perspective in certain risk groups (geriatric patients, cancer patients, patients with neurodegenerative disorders and critically ill patients) and to address the utility of targeted specific nutritional interventions, specifically the high protein nutritional supplements containing β-hydroxy-β-methylbutyrate (HMB) and vitamin D, in terms of potential beneficial effects in preserving and reversing muscle loss beyond meeting nutritional requirements.…”
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