Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system. by Yoav E Timsit, Masahiko Negishi

“…Induction of HSP70 levels by heat shock also increased cytoplasmic CAR levels, similar to the effect of MG132. …”
Get full text

Schistosome egg antigen stimulates the secretion of miR-33-carrying extracellular vesicles from macrophages to promote hepatic stellate cell activation and liver fibrosis in schist... by Xin Qi, Yanan Pu, Fanyan Chen, Liyang Dong, Yongbin Ma, Junling Wang, Guo Yin, Di Lu, Xiaojun Chen, Jifeng Zhu, Yalin Li, Sha Zhou, Chuan Su

“…Mechanistically, EVs derived from SEA-stimulated Mφ contained increased miR-33, which were transferred into HSCs and subsequently upregulated autocrine TGF-β1 in HSCs through targeting and downregulating SOCS3 expression, thereby promoting HSC activation. …”
Get full text

Study on the Denitration Performance of Sulfuric Acid-Modified Columnar Catalysts Derived from Rare Earth Tailings by Qie Junmao, Xu Tong, Zhao Zefeng

“…Currently, the massive accumulation of Bayan Obo rare earth tailings in Baotou City, Inner Mongolia, has imposed significant pressure on the local ecological environment. …”
Get full text

Regenerative and Innovative Utilization of Coffee Residue and Waste Cooking Oil: Improving Rheological Properties of Recycled Asphalt by Ruipeng Zhu, Chunhua Hu

“…Currently, there is limited research on the utilization of spent coffee grounds (SCG) in asphalt pavement. …”
Get full text

Smart Packet Delivery in Mobile Underwater Sensors Networks (M-CTSP) by Abdul Khan, Miguel-Angel Luque-Nieto, Ali Akbar Siddique

“…This research is focused on leveraging the Travelling Salesman Problem (TSP) to establish the optimal route of getting from a source node to a destination node in an underwater dynamic location. In this context, all nodes are mobile and slightly adjust their positions due to water currents. …”
Get full text

Supply Chain Model for Mini Wind Power Systems in Urban Areas by Isvia Zazueta, Edgar Valenzuela, Alejandro Lambert, José R. Ayala, Rodny Garcia

“…The pursuit of energy security has become one of the most important challenges facing modern societies worldwide. The increase in energy consumption and the need to promote sustainability puts pressure on power generation systems. …”
Get full text

Multiple citizenship: international experience and implementation in Ukraine (economic, political and security aspects) by S. Denysiuk, V. Kononenko, N. Rezenkina

“… The article is dedicated to the study of issues related to multiple citizenship in the context of international law and security. In the current conditions of increasing globalization, the regulation of multiple citizenship is becoming ever more relevant, particularly in terms of national security and state sovereignty. …”
Get full text

Multiscale effects of climate change and anthropogenic activity on vegetation dynamics in Guangdong-Hong Kong-Macao greater bay area by Yun Tang, Yuanyuan Wang, Quanming Yang

“…The results reveal that: NDVI exhibits an increasing trend in most regions, Land Surface Temperature (LST) has significantly increased, and the intensity of anthropogenic activities has significantly intensified in half of the regions. …”
Get full text

Lab-in-a-Tip: a multiplex immunoassay platform based on a self-assembled barcoded protein array by Yiran He, Min Jiang, Zhenlong Liang, Zhaoxu Luo, Jingyi Qin, Ye Shen, Yayun Gu, Xiaodong Ma, Hong Wang, Xin Li, Ying Shi, Yanhua Chen, Kefeng Pu, Jiong Li

“…Abstract High throughput immunoassay is increasingly crucial for both scientific and clinical applications. …”
Get full text

Acute beneficial effects of a functional energy shot on cognitive performance and mood states during cognitively demanding task performance: a randomized, double-blind, placebo-con... by Olivia K. O’Shea, Olivia K. O’Shea, Nathan Lawley, Anna Azzopardi, Allison Gutkowski, Michelle Murphy Niedziela, Rachel Horn, David O. Kennedy, Jason Adamson

“…IntroductionFunctional beverages are increasingly popular but it is important to validate their purported effects through research. …”
Get full text

M1 macrophages – unexpected contribution to tumor progression by Olga V. Kovaleva, Madina A. Rashidova, Vasiliy V. Sinyov, Olga S. Malashenko, Alexei Gratchev, Alexei Gratchev

“…In this review, we examine the complex, context-dependent function of M1 macrophages and reassess current strategies aimed at enhancing their cytotoxicity. …”
Get full text

Ukrainian-Polish Relations Through the Prism of Scientific Schools of International Relations by Tetiana Yelova, Antonina Shulіak

“…The study applies methods of theoretical analysis, comparative research, interpretation, and systems thinking to investigate the evolution and current state of Ukrainian-Polish relations against the backdrop of EU enlargement. …”
Get full text

Association of plasma levels of Sestrin2 with adiposity and metabolic function indices in healthy and diabetic subjects from Qatar Biobank by Muhammad Ammar Zahid, Shahenda Salah Abdelsalam, Hicham Raïq, Hanan H. Abunada, Aijaz Parray, Abdelali Agouni

“…Conversely, in the diabetic cohort, higher Sestrin2 levels were paradoxically linked to increased triglycerides (OR: 1.57), the product of triglyceride glucose and waist circumference (OR: 1.8), body fat (OR: 1.72), waist circumference (OR: 1.82), waist-to-hip ratio (OR: 1.96) and metabolic syndrome (OR: 1.48).ConclusionsThese findings suggest that Sestrin2 may play a complex and context-dependent role in metabolic regulation, potentially serving as a protective factor in healthy individuals but contributing to metabolic dysfunction in the context of established diabetes. …”
Get full text

Methodology for Managing Financial Resources in Credit Institutions by A. G. Mikheev

“…The current state of credit and banking sector is characterized by high competition between credit institutions, taking place in context of increasing business volatility. …”
Get full text

Enhancing malaria elimination in high-transmission settings: the synergy of concurrent vector control and chemotherapy by Ronald Mulebeke, Adoke Yeka, Jean-Pierre van Geertruyden

“…This report aims to review the available evidence on the strategies and deployment of current tools targeting vectors and parasites in resource-limited settings, focusing on sub-Saharan Africa. …”
Get full text

PSG-Pair: A Psychological Snapshot Guided Model for Improved Query-Response Pairing in Psychological Wellness Communities for University Students by Yongsheng Ma, Xianhui Sun, Aiqun Ma

“…Additionally, while the current evaluation metrics adequately reflect the retrieval and pairing capabilities, there is a need for the development of more tailored evaluation systems to assess models within the unique context of psychological wellness support for university students. …”
Get full text

Evaluating Generative AI in Mental Health: Systematic Review of Capabilities and Limitations by Liying Wang, Tanmay Bhanushali, Zhuoran Huang, Jingyi Yang, Sukriti Badami, Lisa Hightow-Weidman

“…ObjectivesThis systematic review aims to evaluate the current capabilities of generative artificial intelligence (GenAI) models in the context of mental health applications. …”
Get full text

Review: Application of Protein-Based Raw Materials in Health Foods in China by Hao Duan, Gaigai Liu, Jiaqi Liu, Zhuoye Wang, Shuyuan Bao, Xinyue Chang, Wenjie Yan

“…Finally, based on these studies, this paper discusses suggestions for raw protein materials in the future development of health food in China and also discusses the limitations of the current research in this review.…”
Get full text

CircPWWP2A promotes renal interstitial fibrosis through modulating miR-182/ROCK1 axis by Qian Huang, Kaiyi Zhong, Jiali Wei

“…Despite ongoing research, the mechanisms underlying renal fibrosis are still not well understood, and there is currently a lack of effective treatments available. …”
Get full text

Morphological features of the poultry thymus by S. V. Huralska, N. V. Dyshliuk, S. S. Zaika, H. P. Hryshchuk, L. H. Yevtukh

“…Efforts to preserve the population and increase their productivity are directly related to strengthening poultry immunity and the state of their immune system. …”
Get full text