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2601
Platelet glycoprotein VI promotes folic acid-induced acute kidney injury through interaction with tubular epithelial cell-derived galectin-3
Published 2025-03-01“…Additionally, we utilized platelet GPVI-specific knockout mice in conjunction with TD139, a small-molecule inhibitor of galectin-3, to explore the effects of inhibiting the galectin-3-GPVI interaction on FA-AKI. Results In the current study, we observed that mouse platelets displayed hyperactivity in the context of functional acute kidney injury (FA-AKI). …”
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2602
SolarSegNet: A multimodal frequency-aware network for photovoltaic power stations extraction using Sentinel-1 and Sentinel-2 images in coastal China
Published 2025-08-01“…Current deep learning-based remote sensing methods for photovoltaic (PV) power stations identification primarily focus on inland high-irradiance areas, but exhibit significant limitations in accurately delineating boundary of multi-scale PV power stations in coastal regions. …”
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2603
Readiness of future teachers to work at school: Review of theoretical and empirical research
Published 2024-02-01“…Introduction. The current review article studies and systematises modern knowledge about the readiness of future teachers to work at school. …”
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2604
Modelling of biological age in stable and acute exacerbations of chronic obstructive pulmonary disease
Published 2025-08-01“…Biological age (BA), a novel metric for gauging the extent of aging, has rarely been investigated in the context of acute exacerbation of COPD (AECOPD). Our study aimed to elucidate the association between BA and AECOPD, thereby highlighting the potential of BA as a predictive tool in clinical practice. …”
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2605
Changes in tree-ring wood density of European beech (Fagus sylvatica L.), silver fir (Abies alba Mill.), and Norway spruce (Picea abies (L.) H. Karst.) in European mountain forests...
Published 2024-12-01“…Abstract Key message We found a significant increase in the latewood density of European beech, and a decrease in the latewood and mean wood density of silver fir and Norway spruce in European mountain forests over the period 1901–2016. …”
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2606
Anticancer Potential, Phenolic Profile, and Antioxidant Properties of <i>Synsepalum dulcificum</i> (Miracle Berry) in Colorectal Tumor Cell Lines
Published 2025-03-01“…Polyphenols, recognized for their antioxidant capacity, have shown potential in improving the response treatment of various diseases, including cancer. In this context, polyphenols have the ability to induce cytotoxicity in tumor cells, making them possible complementary agents to current treatments. …”
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2607
Process design and techno-economic analysis of integrated coal gasification-flash ironmaking-methanol synthesis process
Published 2024-01-01“…The internal rate of return, payback period, net present value, and return on investment are estimated as 26%, 1018 million, 22.65%, and 3.20 years based on current prices, respectively. Meanwhile, the influences of coal and iron ore prices and iron and methanol prices on economic performance are explored.…”
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2608
Effect of Positioning on Oxygenation and Hemodynamics among Patients on Mechanical Ventilation
Published 2024-04-01“… Context: The routine practice of positioning is a vital procedure in critical care units, especially when prophylaxis is the aim. …”
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2609
The “New Normal” in China’s Assertive Power Projection in the South China Sea: Maritime Hybrid Threats
Published 2021-11-01“…Therefore, this study aims to shed light on the context and cumulative effects of China’s assertive employment of maritime hybrid instruments while discussing increasing international concerns on the altering dynamics of balance of power.…”
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2610
Participant perceptions of Range Rider Programs operating to mitigate wolf–livestock conflicts in the western United States
Published 2016-09-01“…We conducted semistructured phone and personal interviews with 51 participants from 17 RRPs in Montana, Oregon, and Washington during January to April 2014 and October 2014 to January 2015 to develop a typology of NRM RRPs and assess participant perceptions of current programs. Although the RRPs we studied varied in context, program focus, and scale, they shared similar organizational components that included a sponsor; collaboration among several organizations; a funding mechanism; a structure that included a supervisor, the landowner(s), and the range rider(s); and a mechanism for stakeholder feedback. …”
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2611
The association between type 2 diabetes and asthma incidence: a longitudinal analysis considering genetic susceptibility
Published 2025-01-01“…After adjusting for age, sex, current smoking status, and other confounding variables, T2D was significantly associated with an increased risk of developing asthma (Hazard Ratios [HR] 1.16, 95% confidence interval [CI] 1.06–1.26). …”
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2612
Using Legume-Enriched Cover Crops to Improve Grape Yield and Quality in Hillside Vineyards
Published 2024-10-01“…Natural covering (NATC) has spread on hillside vineyards of central Italy as a replacement for tillage to reduce soil erosion, although it increased nitrogen and water needs. Therefore, in the current context of global warming, using cover crops (CCs) that require less water and provide nitrogen becomes crucial. …”
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2613
Development and Dynamic Numerical Evaluation of a Lightweight Sports Helmet Using Topology Optimization and Advanced Architected Materials
Published 2025-02-01“…Hence, in the last decades, the scientific interest has been focused on establishing head injury criteria and improving the helmet design with the ultimate goal of the reduction in injury probability and increasing the athlete’s performance. In this context, the current study aims to develop a lightweight sports helmet with increased safety performance, utilizing topology optimization processes and advanced architected materials. …”
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2614
Histopathological study of the testes in three genetic lines of Japanese quail (Coturnix japonica) exposed to different doses of L-Arginine
Published 2025-06-01“…Birds were divided by color into three groups and fed diets containing different arginine levels from age 30 to 90 days. …”
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2615
Dopamine modulates persistent synaptic activity and enhances the signal-to-noise ratio in the prefrontal cortex.
Published 2009-08-01“…When the background DA was eliminated by depleting DA with reserpine and alpha-methyl-p-tyrosine, or by preparing corticolimbic co-cultures without the VTA slice, Up-states could be enhanced by low concentrations (0.1-1 microM) of DA that had no effect in the VTA containing cultures. Finally, in spite of the concentration-dependent effects on Up-states, exogenous DA at all but the lowest concentrations increased intracellular current-pulse evoked firing in all cultures underlining the complexity of DA's effects in an active network.…”
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2616
In vitro and preclinical evaluation of the antifungal activity of 6-methoxy-1 H-indole-2-carboxylic acid produced by Bacillus toyonensis strain OQ071612 formulated as nanosponge hy...
Published 2025-04-01“…Abstract Background In a previous study, 6-methoxy-1 H-indole-2-carboxylic acid (MICA) was isolated from the culture broth of Bacillus toyonensis strain OQ071612 soil isolate in our laboratory, and it demonstrated promising antifungal activities. The current study was designed to create a nanosponge (NS)-hydrogel (HG)-containing MICA followed by in vitro and preclinical evaluation for potential clinical use in the topical treatment of mycotic infections. …”
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2617
Malted Multi-millet based Probiotic Dairy Beverage: Nutritional, Sensory, Physicochemical and Microbiological Characterization
Published 2025-07-01“… In the current study conducted during November, 2023–April, 2024 , malted multimillet flours (MMF) viz., Finger millet, Foxtail millet and Little millet were used for preparation of probiotic lassi. …”
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2618
Optimization of the defense forces personnel under mobilization conditions: The role of occupational selection as a personnel allocator
Published 2024-12-01“…The second problem is the age aspect in the ranges of 20-30, 30-40 and 40-60 years, for which it is necessary to develop and apply the criteria of occupational suitability for each of the currently relevant professions. A generalized definition of the psychological readiness state was formulated as a stable, multifaceted and hierarchically structured result of preparation for a certain activity, which contains a number of subsystems adequate to the requirements, content and conditions of the activity. …”
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2619
New multifactor spatial prediction method based on Bayesian maximum entropy
Published 2013-11-01“…., organic matter and heavy metal content) are vital to soil quality evaluation and regional environment assessment. Currently, the spatial distribution of soil properties is usually predicted with classical geostatistics or environmental correlation. …”
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2620
Conformity of Tourism Higher Education with Tourism Development Goals: Focusing on Tourism Undergraduate Program in Iran
Published 2025-03-01“…Adopting a qualitative approach, it compares the current state of tourism higher education in Iran with its ideal state. …”
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