Oral vs. Outpatient Parenteral Antimicrobial Treatment for Infective Endocarditis: Study Protocol for the Spanish OraPAT-IE GAMES Trial by Guillermo Cuervo, Marta Hernández-Meneses, Arístides de Alarcón, Rafael Luque-Marquez, María M. Alonso-Socas, Ana López-Lirola, Víctor González-Ramallo, Ane J. Goikoetxea-Agirre, David Nicolás, Miguel A. Goenaga, Esperanza Merino, Francesc Escrihuela-Vidal, Pilar Martín-Dávila, Belén Loeches, Lucía Boix-Palop, Oriol Gasch, Marta Camprecios, Alicia Hernández-Torres, Lara García-Álvarez, Marcos Pajarón, María Angels Ribas, Rosa Blanes-Hernández, Inmaculada López-Montesinos, Luis E. López-Cortés, Bárbara Vidal, Mariana Fernández-Pittol, Dolores Navarro, Asunción Moreno, Coral Sala, Juan Ambrosioni, José M. Miró, OraPAT-IE GAMES Investigators

“…Conclusion In a global context of limited healthcare resources and a sustained increase in elderly and frail patients, it is of great importance to demonstrate the effectiveness and safety of outpatient management strategies that could reduce the duration of conventional hospitalizations with their potential complications and inherent costs. …”
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Combined and progestagen-only hormonal contraceptives and breast cancer risk: A UK nested case-control study and meta-analysis. by Danielle Fitzpatrick, Kirstin Pirie, Gillian Reeves, Jane Green, Valerie Beral

“…<h4>Background</h4>Current or recent use of combined oral contraceptives (containing oestrogen+progestagen) has been associated with a small increase in breast cancer risk. …”
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Fastest Prostate Cancer Prediction on Whole-Mount Pathological Slides Using Self-Reform Multilayer Transformer by Linjie Xu, Xiaotian Yu, Haoming Luo, Jili Wang, Wenjie Liang, Jing Zhang, Zunlei Feng, Cheng Lu, Xiuming Zhang

“…Moreover, pixels in each whole-mount slide of PCa are increased by approximately <inline-formula> <tex-math notation="LaTeX">$4\sim 9$ </tex-math></inline-formula> times, therefore containing more information for diagnosis. …”
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Study of the influence of pulse heating on the structure and properties of reinforcing fibers from tungsten-rhenium alloys by V. Shalomeev, S. Sheyko, O. Hrechanyi, T. Vasilchenko, V. Vinichenko, O. Korobko

“…The component that largely determines the strength and technological properties of the composite is the fibers. Currently the requirements for the strength and technological properties of reinforcing fibers are quite fully met by wires made of various tungsten-rhenium and molybdenum-rhenium alloys. …”
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The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

“…Bioinformatics analysis showed Cti6 is conservative in Aspergillus spp., and mCherry mediated subcellular localization showed that most Cti6 accumulated in the nuclei, which reflected that Cti6 performed its important biological function in the nuclei in Aspergillus spp.. The results of the current study elucidate the roles of PHD domain containing proteins in the mechanism of the infection of crops by A. flavus, and provided a novel target for effectively controlling the contamination of Aspergillus spp. to crops.…”
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Hepatoprotective and antioxidant effects of Glycyrrhiza glabra extracts against TCDD-induced hepatocyte damage in Jian carp (Cyprinus carpio var. Jian) by Du Jinliang, Cao Liping, Jia Rui, Liu Yingjuan, Shen Yujin, Yin Guojun

“…Jian).Jian carp were fed with diet containing 3 doses of GGE (0.1, 0.5 and 1.0 g/kg diet) for 60 days before a single intraperitoneal injection of TCDD (0.6 μg/kg), 72 h after TCDD injection, blood and liver samples were taken for biochemical analysis.The results showed that GGE at 1.0 g/kg diet for 60 days prior to TCDD intoxication significantly reduced the elevated activities of ALT, AST, LDH, AKP and increased the reduced levels of total protein (TP), albumin (Alb) in the serum, markedly inhibited the reduction of the activities of superoxide dismutase (SOD), glutathione peroxidase (GPx), catalase (CAT), total antioxidant capacity (T-AOC), and reduced the malondialdehyde (MDA) formation in liver tissue. …”
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Anatomy and function of closing muscle complex of the vagina in health and pelvic organ prolapse by G. B. Dikke, A. D. Makatsariya, A. M. Ziganshin, E. A. Shaikhieva, V. O. Bitsadze

“…In modern literature, the pelvic floor muscles are presented by showing their anatomical location and indicating relevant attachment points, but their combined anatomical, topographic and functional significance is described insufficiently, which the current review was aimed at.Aim: to determine the physiological significance and anatomical units of the vagina occlusor muscle complex, topography and functions in health and in pelvic organ prolapse (POP).Materials and Methods. …”
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Antiviral Therapeutics Discovery for Enterovirus D68. by Prof Justin Jang H Chu

“…To date, there are no effective antiviral successfully developed for enterovirus infection and the current understanding on pathogenesis is limited, which has resulted in the persistent circulation and outbreaks across the globe. …”
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Leishmaniases in Ethiopia: a scoping review by Ermias Diro, Fiona Wallace, Mezgebu Silamsaw Asres, Richard Wamai, Hugh Shirley, Grace Grifferty, Eleni Ayele, Katherine O’Brien, Adriana Totten, Philip Coombs, Adrienne M Orriols, Shreyas Mosurkal, Ellie Krulwich, Leah Oruko, Isabel C Roman, Prapti Shah, Riley Fanning-Hughes, Abigail L Williams, Morgan G Wong, Sophia Roe, Khushi Gandhi, Laith Matari, Sara Shaikh, Abigail Binkley, Benjamin J D Boutselis, Amer Chaudhry, Mahlet Haile

“…The identified studies were analysed using an extensive codebook, which was previously developed by this team and adapted to the Ethiopian context to classify the research into different categories.Results A total of 8698 articles were identified. …”
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Promising opportunities to improve polio vaccines by E. E. Evreinova, L. M. Khantimirova, V. A. Shevtsov, V. A. Merkulov, V. P. Bondarev

“…In order to meet the needs of global health, it is planned to increase the use of traditional and optimised inactivated polio vaccines and introduce new types of vaccines that are being developed based on the current understanding of RNA-containing viruses. …”
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Impact of Misting Systems on Local Particulate Matter (PM) Levels by William L. Knight, Matthew P. Fraser, Pierre Herckes

“…These experiments show PM concentrations decrease with increasing distance from misting systems. …”
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The Effect of Monetary Rewards on the Performance of Employees in an Organisation: A Case Study of Kabale District Local Government. by Nayebare, Gaston

“…Though, some of the major goals of training employees contain, increase in production, lesser labor turnover rate, higher confidence and better management and training facilitates to decrease cost as it enhances productivity, and promotes objective congruency. …”
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Cryo-EM and cryo-ET reveal the molecular architecture and host interactions of mycobacteriophage Douge by Jitendra Maharana, Chun-Hsiung Wang, Li-An Tsai, Yi-Ting Liao, Cheng-Han Yang, Melvin C. Shen, Lourriel S. Macale, Thang Ngoc Tran, Joemark Narsico, Ronelito J. Perez, Sunil Kumar Tewary, Jian-Li Wu, Hong-You Lin, Shu-Wei Chang, Aaron Franklin, Patrick J. Moynihan, Deborah Jacobs-Sera, Krista G. Freeman, Graham F. Hatfull, Todd L. Lowary, Meng-Chiao Ho

“…Molecular insights into mycobacteriophage architecture and host interactions could allow structure-guided phage engineering to increase efficacy and broaden host range, but such information is currently unavailable. …”
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SEED DORMANCY BREAKING OF AN ENDANGERED MEDICINAL TREE SPECIES (TAXUS BACCATA L.) USING EMBRYO CULTURE by Mohamed BEKHOUCHE, Abdelkader MORSLI, Majda KHELIFI-SLAOUI, Roukia BENYAMMI, Hayette ZAOUT, Lakhdar KHELIFI

“…These results indicated that the protocol developed during the current study will be useful to overcome seed dormancy and for multiplication and conservation of the species T. baccata L. …”
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Reassessing immediate coal phase-out: Dual imperatives of capacity control and renewables expansion in China’s net-zero strategy by Jiaxing Wang, Xi Lu, Hao Wang, Yang Ou, Jianxiao Wang, Dan Tong, Yan Li, Ziwen Ruan, Zihua Yin, Wenlong Zhou, Benjamin McLellan, Emily Xing, Anna M. MacLennan, Jingli Fan, Xian Zhang, Michael B. McElroy, Kebin He

“…Broader context: Reducing CO2 emissions in power systems is crucial for China in achieving its net-zero emission target. …”
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Developing and presenting a mathematical model for the purpose of organizational culture architecture based on creating alignment between the strategic reference points of organiza... by Elyas hasanzadeh Shweili, Mir Mehrdad peidaie, Ali reza Rezghi Rostami

“…These values ​​are the focus of many organizational phenomena, such as organizational culture; which provides the context of self-control and counter-control and gives it direction (Abedelrahim, 2018). …”
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Parathyroid hormone administration improves bone marrow microenvironment and partially rescues haematopoietic defects in Bmi1-null mice. by Ruinan Lu, Qian Wang, Yongli Han, Jianyong Li, Xiang-Jiao Yang, Dengshun Miao

“…The mice were treated with PTH1-34 (containing the first 34 residues of mature PTH), an anabolic drug currently used for treating osteoporosis, and compared with the vehicle-treated Bmi1-/- and wild-type littermates in terms of skeletal and haematopoietic phenotypes. …”
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Do we need urine drug screens in opioid addiction treatment: An observational study on self-report versus urine drug screens by Alannah McEvoy, Myanca Rodrigues, Brittany B Dennis, Jacqueline Hudson, David C. Marsh, Andrew Worster, Lehana Thabane, Zainab Samaan

“…It is therefore important to consider the context of the patient, and the type of the co-substance used to select patient-centred testing as indicated. …”
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Advancing life cycle assessment of bioenergy crops with global land use models by Anders Arvesen, Florian Humpenöder, Tomás Navarrete Gutierrez, Thomas Gibon, Paul Baustert, Jan Philipp Dietrich, Konstantin Stadler, Cristina-Maria Iordan, Gunnar Luderer, Alexander Popp, Francesco Cherubini

“…We find that land use-related CO _2 emission for bioenergy range from 2 to 35 tonne TJ ^−1 , depending on bioenergy demand, policy context, year and accounting method. GHG emissions per unit of bioenergy do not increase with bioenergy demand in presence of an emission tax. …”
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The Symbiotic Bacterial Profile of Laboratory-Reared and Field-Caught <i>Aedes albopictus</i> Mosquitoes from Greece by Elias Asimakis, Ioannis Galiatsatos, Georgia Apostolopoulou, Eleni C. Savvidou, Georgios Balatsos, Vasileios Karras, Vasiliki Evangelou, Eva Dionyssopoulou, Antonios Augustinos, Nikos T. Papadopoulos, Antonios Michaelakis, Panagiota Stathopoulou, George Tsiamis

“…The use of symbiotic bacteria to improve the application of SIT or design combined SIT/incompatible insect technique (IIT) approaches is currently considered. In this context, exploring the microbiota of local mosquito populations is crucial for identifying interesting components. …”
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