Development of <i>OptiCon</i>: A Mathematical Model with a Graphical User Interface for Designing Sustainable Portland Cement Concrete Mixes with Budget Constraint by Angie Pineda, Rita Peñabaena-Niebles, Gilberto Martínez-Arguelles, Rodrigo Polo-Mendoza

“…However, designing PCCs with simultaneous contents of SCMs and RCA is not easily manageable because current design procedures fail to adjust all of the variables involved. …”
Get full text

Availability of trace minerals in feed ingredients and supplemental sources (inorganic, organic, and nano) in broiler chickens by Junhyung Lee, Minju Kim

“…At d 15 of age, a total of 480 birds, one-day-old Ross 308 males, were used in the current trial and housed in metabolic cages for chickens. …”
Get full text

MEANS AND METHODS OF STIMULATION OF SALIVATION (LITERATURE REVIEW) by N.O. Riabushko

“… Currently, a large number of tools and methods are proposed to reduce dryness in the mouth and restore the deficiency of biologically active substances entering the mouth with saliva. …”
Get full text

NMDA Receptor–Mediated Ca2+ Flux Attenuated by the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin by Jordan Casby, Benjamin M. Gansemer, Stanley A. Thayer

“…Incubating cultures in Mg2+‐free buffer containing tetrodotoxin, 6‐cyano‐7‐nitroquinoxaline‐2,3‐dione, and bicuculline for 30 min inhibited NMDA‐evoked increases in intracellular Ca2+ concentration ([Ca2+]i) recorded at 22°C by 50% ± 18% and prevented inhibition by brophenexin. …”
Get full text

Impact of Metal Source Structure on the Electrocatalytic Properties of Polyacrylonitrile-Derived Co-N-Doped Oxygen Reduction Reaction Catalysts by Arseniy Kalnin, Ksenia Kharisova, Daniil Lukyanov, Sofia Filippova, Ruopeng Li, Peixia Yang, Oleg Levin, Elena Alekseeva

“…We have proposed a multifunctional active metal source strategy based on the cobalt complex with the ligand containing pyridine and azo-fragments. This complex simultaneously provides the nitrogenous environment for the Co atoms and acts as a blowing agent due to N₂ extrusion, thus increasing the surface area and porosity of the material. …”
Get full text

Novel Nanotechnology of TiO2 Improves Physical-Chemical and Biological Properties of Glass Ionomer Cement by Daniela Dellosso Cibim, Miki Taketomi Saito, Priscila Alves Giovani, Ana Flávia Sanches Borges, Vanessa Gallego Arias Pecorari, Orisson Ponce Gomes, Paulo Noronha Lisboa-Filho, Francisco Humberto Nociti-Junior, Regina Maria Puppin-Rontani, Kamila Rosamilia Kantovitz

“…Furthermore, regardless of TiO2 concentration, no significant effect was found on SR, whereas GIC-containing 7% TiO2 presented decreased SH values. Fluoride release lasted longer for the 5% and 7% TiO2 groups, and cell morphology/spreading and ECM composition were found to be positively affected by TiO2 at 5%. …”
Get full text

Consequences, costs and cost-effectiveness of workforce configurations in English acute hospitals by Peter Griffiths, Christina Saville, Jane Ball, David Culliford, Jeremy Jones, Francesca Lambert, Paul Meredith, Bruna Rubbo, Lesley Turner, Chiara Dall’Ora

“…Study registration This study is registered as Current Controlled Trials ClinicalTrials.gov NCT04374812. …”
Get full text

Recent process in organic near-infrared fluorescent probes for detecting hypochlorous acid/hypochlorite by Zhongchang Wang, Chenzheng Guan, Wenxu Lu, Liangchao Yuan, Man Chao, Hai-Liang Zhu, Tingwu Liu

“…Finally, we outline future prospects, aiming to inspire innovative designs that will overcome current bottlenecks and propel the field towards clinical translation. …”
Get full text

Cybersecurity requirements for medical devices in the EU and US - A comparison and gap analysis of the MDCG 2019–16 and FDA premarket cybersecurity guidance by Max Ostermann, Rebecca Mathias, Fatemeh Jahed, Mitchell B. Parker, Florence D. Hudson, William C. Harding, Stephen Gilbert, Oscar Freyer

“…The increasing use of connected medical devices has led to substantial cybersecurity challenges, putting patient safety and the integrity of healthcare infrastructures at risk. …”
Get full text

Assessment of the Chemical Composition and Antioxidant Capacity of Flowers, Seeds, and Seed Cake of Cactus Pear (<i>Opuntia ficus-indica</i> L.) and Their Application in Biscuits by Fatiha Brahmi, Amira Oufighou, Leila Smail-Benazzouz, Nouna Hammiche, Lydia Hassaine, Lila Boulekbache-Makhlouf, Khodir Madani, Federica Blando

“…Functional ingredients rich in bioactive compounds can be added to conventional ingredients for the formulation of food to increase its nutraceutical potential. Three prickly pear parts, namely flowers, seeds, and seed cake were utilized in the current work as natural antioxidant resources. …”
Get full text

In Vitro and In Vivo Comparison of Changes in Antibiotics Susceptibility of E. coli and Chicken’s Intestinal Flora after Exposure to Amoxicillin or Thymol by Soukayna Hriouech, Ahmed A. Akhmouch, Mariam Tanghort, Hanane Chefchaou, Aouatef Mzabi, Najat Chami, Adnane Remmal

“…E. coli strain was subcultured on agar plates containing increasing concentrations of either amoxicillin or thymol. …”
Get full text

The state of drained peatlands in the Middle Urals and prospects of their use for carbon farming by Seyed Omid Reza Shobairi, Alenakochubei, Olga Cherepanova, et al.

“…The global change of the planet's climate is associated with increased concentration of greenhouse gases in the atmosphere, which is the result of irrational human economic activity. …”
Get full text

Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34+ Cells by Hui Xie, Li Sun, Liming Zhang, Teng Liu, Li Chen, Aiqi Zhao, Qian Lei, Fei Gao, Ping Zou, Qiubai Li, An-yuan Guo, Zhichao Chen, Hongxiang Wang

“…We speculate that MSC-MVs may recapitulate the hematopoiesis-supporting effects of their parent cells. In the current study, we found MSC-MVs containing microRNAs that are involved in the regulation of hematopoiesis. …”
Get full text

Optimization of The Budget of The Industrial Complex Transformation Strategy Based on Neural Network Modeling by A. G. Boev, A. G. Puzakov, Yu. P. Anisimov

“…Currently, Russian industry is developing mainly along an extensive path that does not provide a deep innovative transformation of business and the necessary increase in labor productivity.Materials and methods. …”
Get full text

Role of tertiary lymphoid structures and B cells in clinical immunotherapy of gastric cancer by Weiyi Chen, Lingli Zhang, Man Gao, Ning Zhang, Rumeng Wang, Yang Liu, Yan Niu, Lizhou Jia, Lizhou Jia

“…Mature TLSs are B-cell regions containing germinal centers. During germinal center formation, B cells undergo transformations to become mature cells with immune function, exerting anti-tumor effects. …”
Get full text

Fatty fried food toxins as triggering stimuli to immune system interplay in global autoimmune diseases: A systematic review by Saba Anwar, Qamar Abbas Syed, Mahnoor Saleh, Muhammad Saad Akram, Ghayyor Sultan, Sahar Khalid, Anum Ishaq, Gholamreza Abdi, Rana Muhammad Aadil

“…The purpose of the current systematic review was to respond to the following query: Does the rising level of fatty fried food consumption trigger the major autoimmune diseases such as Crohn's disease, ulcerative colitis, rheumatoid arthritis, systemic lupus erythematous, and multiple sclerosis? …”
Get full text

Topological transformation of microbial proteins into iron single-atom sites for selective hydrogen peroxide electrosynthesis by Xiaofeng Xiao, Zechao Zhuang, Shuhu Yin, Jiexin Zhu, Tao Gan, Ruohan Yu, Jinsong Wu, Xiaochun Tian, Yanxia Jiang, Dingsheng Wang, Feng Zhao

“…These moieties resemble the structural features of nonheme Fe-dependent enzymes while being effectively confined on a microbe-derived, electrically conductive carbon support, enabling high-current density electrolysis. A comparative analysis involving catalysts derived from eleven representative microbes reveals that the presence of 0.05 wt% Fe single-atom sites leads to a significant 26% increase in hydrogen peroxide selectivity. …”
Get full text

Impaired plasma membrane calcium ATPase activity and mitochondrial dysfunction contribute to calcium dysregulation in Fabry disease-related painful neuropathy by Francesco Formaggio, Asia Pizzi, Cecilia Delprete, Davide Pasqualini, Isabella Mataloni, Roberto Rimondini, Ludovica Campolongo, Vincenzo Donadio, Anna Maria Ghelli, Rocco Liguori, Marco Caprini

“…The reduced activity was associated with a decrease of cytosolic pH which weakened the PMCA-dependent calcium extrusion. …”
Get full text

Exercise Promotes Hippocampal Neurogenesis in T2DM Mice via Irisin/TLR4/MyD88/NF-κB-Mediated Neuroinflammation Pathway by Haocheng Xu, Xin Tian, Yuanxin Wang, Junjie Lin, Baishu Zhu, Chen Zhao, Bin Wang, Xin Zhang, Yu Sun, Nan Li, Xun Sun, Fanxi Zeng, Mingzhi Li, Xiquan Ya, Renqing Zhao

“…Moreover, exercise markedly increased the levels of fibronectin type III domain-containing protein 5 (FNDC5)/irisin protein while decreasing the expression of Toll-like receptor 4 (TLR4), myeloid differential protein-88 (MyD88), and nuclear factor kappa-B (NF-κB) in the hippocampus of T2DM mice. …”
Get full text

Optimizing AI models to predict esophageal squamous cell carcinoma risk by incorporating small datasets of soft palate images by Kotaro Waki, Katsuya Nagaoka, Keishi Okubo, Masato Kiyama, Ryosuke Gushima, Kento Ohno, Munenori Honda, Akira Yamasaki, Kenshi Matsuno, Yoki Furuta, Hideaki Miyamoto, Hideaki Naoe, Motoki Amagasaki, Yasuhito Tanaka

“…Previously, we found that specific soft palate morphologies are strongly associated with increased ESCC risk. However, there is currently no artificial intelligence (AI) system that utilizes oral images for ESCC risk assessment. …”
Get full text