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4201
From waste to weapon: the potential of medicinal plant waste extracts for eco-friendly crop disease management
Published 2025-03-01“…The increasing challenge of managing crop diseases requires innovative and sustainable approaches. …”
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4202
OPTIMIZATION OF IMID-BASED THERAPIES
Published 2024-12-01“…In this case, it is clear that multiple myeloma treatment optimization cannot be achieved by considering multiple myeloma treatment only as applying the appropriate drug combination.In order to ensure the optimization of IMID-based therapies, it is necessary to take a broad perspective.This perspective should include the correct selection of the patient to be treated with IMID, the development and implementation of IMID forms that will increase patient compliance, the use of techniques to predict the development of resistance, side effect management during treatment, preventing the increase in disease burden with appropriate maneuvers by following the disease burden after treatment, and drug-free follow-up.It is recommended to avoid thalidomide in the presence of peripheral neuropathy, to prefer other agents instead of lenalidomide in the presence of renal function loss, and to avoid pomalidomide in patients with COPD.Nex-20, a once-monthly subcutaneous formulation of lenalidomide, is expected to be an important breakthrough in improving patient compliance.Prediction of which patients will develop resistance will be very useful in order to have the best treatment outcomes.Calculation of miRNA risk scores, measurement of lenalidomide metabolite levels in urine, measurement of cereblon levels in blood, or immunohistochemical detection of cereblon levels are some of the methods currently being tried to predict disease resistance.Patients who develop anemia should be treated with erythropoietin, skin reactions should be treated with steroids and antihistamines, diarrhea should be treated with loperamide and colestyramine, and in general, the drug should be discontinued and the same dose or a lower dose should be insisted upon.An important part of treatment is maintenance therapy with lenalidomide. …”
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4203
Justification of military neutrality of the Republic of Serbia at a time of erosion of neutrality in Europe
Published 2023-01-01“…The first chapter briefly describes the historical decline of neutrality during the first half of the 20th century. In that context, observation made in mid last century, according to which neutrality was becoming an obsolete concept, is true. …”
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4204
Transition Effects in Bridge Structures and Their Possible Reduction Using Recycled Materials
Published 2024-12-01“…This article serves as a review of the current challenges in bridge engineering, specifically addressing the transition effect and the utilization of recycled materials. …”
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4205
Sustainable Machining Using Eco-Friendly Cutting Fluids: A Review
Published 2022-01-01“…The base fluids of eco-friendly cutting fluids should contain some vegetable oil. Due to their eco-friendly, thermal, and tribological qualities, these types of machining fluids are becoming increasingly popular among researchers throughout the world. …”
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4206
Liquid CO phase transition fracturing technology and its application in enhancing gas drainage of coal mines
Published 2020-12-01“…It utilized phase transition equipment (PTE) consisting of a liquid gas container, control unit for the current and gas volume, heating tube, and other components. …”
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4207
Early Diagnosis of Latent Tuberculosis Reactivation due to Drug Interaction between Cobicistat and Intranasal Fluticasone
Published 2019-01-01“…Single-tablet antiretroviral therapy is currently the first-line choice for the treatment of HIV infection. …”
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4208
Circulating Cell-free Tumor Nucleic Acids in Gastric Cancer
Published 2018-09-01“…Circulating tumor nucleic acids (ctNAs) originate in a tumor and contain tumor-related genetic or epigenetic alterations. …”
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4209
Height Propagation Law and Controlling Strategies of Acid Fractures in Carbonate Gas Reservoirs With Bottom Water Layer Under Different Stress Profiles
Published 2025-01-01“…Acid fracturing is currently employed to develop the carbonate gas reservoir in the second section of the Dengying Formation at the Anyue Gas Field, Sichuan Basin. …”
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4210
The Potential of Plant Extracts Used in Cosmetic Product Applications—Antioxidants Delivery and Mechanism of Actions
Published 2024-11-01“…Natural ingredients have been used in skincare products for thousands of years. The current focus is on novel natural bioactivities that shield the skin from UV rays and free radicals, among other damaging elements, while enhancing skin health. …”
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4211
A review of the foliar application of individual amino acids as biostimulants in plants
Published 2025-05-01“…This review summarises current knowledge on the effects of the foliar application of the 20 most common naturally occurring amino acids. …”
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4212
Prevalence of obstructive sleep apnea in 6- to 12-year-old children in Rajanagaram Mandal – A cross-sectional study
Published 2025-04-01“…The prevalence of sleep apnea is high, and significant adverse effects are associated with this. Hence, the current study assessed the prevalence of sleep apnea in Rajanagaram Mandal. …”
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4213
RETRACTED: Biodiversity Loss with Habitat and Risk of New Diseases
Published 2021-03-01“…The degradation of nature is among the most serious issues that the world faces, but current targets and consequent actions amount, at best, to a managed decline. …”
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4214
Development and characterization of pramipexole dihydrochloride buccal films for Parkinson's disease treatment.
Published 2025-01-01“…Swallowing difficulties present a significant challenge in the treatment of Parkinson's disease patients. Our current experimental work aimed to produce and assess a buccal polymer film containing pramipexole as the active pharmaceutical agent. …”
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4215
Effect of Tapuy (Philippine Rice Wine) Lees on the Gut Microbiota Profile and Lifespan under Normal and Stress Conditions in Drosophila melanogaster
Published 2024-12-01“…These lees have been reported to contain high concentrations of proteins and dietary fibers. …”
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4216
Asymmetry in Distributions of Accumulated Gains and Losses in Stock Returns
Published 2025-06-01“…Our main conclusion is that the current state of theory, which predicts symmetric or near-symmetric distributions of returns, cannot explain the aggregate of empirical results.…”
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4217
Social Media and Logistics: Uncovering Challenges and Solutions Through YouTube Data
Published 2025-04-01“…<i>Methods</i>: This study collects YouTube data containing keywords related to logistics issues—particularly the 2024 problem—and applies natural language processing (NLP) techniques to explore potential solutions. …”
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4218
Mpox in Africa: What we know and what is still lacking.
Published 2025-06-01“…Mpox is endemic in several African countries, and currently, the infection has spread in non-endemic countries, including Rwanda, Uganda, and Kenya. …”
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4219
Teachers' Perception of the Challenges of teaching self-regulated Learning in the classroom: A Phenomenological Study
Published 2024-03-01“…Applying and paying attention to the challenges of teaching self-regulated learning that was raised in the current research has led to an increase in the awareness of teachers, administrators and education officials about this important structure and a way to design interventions and effective planning in order to improve the quality of education and develop students' self-regulated learning. …”
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4220
Analyzing Worn-Out Texture Regeneration from Urban Branding Perspective Using Structural Equation Modeling (SEM) (Case Study: Worn-Out Texture of Shahr-e-Kord)
Published 2024-06-01“…Based on this, the primary aim of the current research was to explain the model of how the components of an urban branding strategy influenced the success of urban regeneration in the dilapidated context of Shahr-e-Kord. …”
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