Cost-effectiveness of atezolizumab plus bevacizumab versus sorafenib as first-line therapy in unresectable hepatocellular carcinoma in the US and Chinese setting: a modelling compa... by Lei Wang, Lulu Liu, Yiling Ding, Qilin Zhang, Yamin Shu

“…In scenario analyses, the atezolizumab plus bevacizumab treatment becomes favourable when the cost of atezolizumab decreases to 67.85% and 18.45% of its original price in the USA and China, respectively.Conclusions The atezolizumab plus bevacizumab is unlikely to be cost-effective compared with sorafenib for patients with unresectable HCC in the context of the USA and China. …”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…CE-MS peptidome analysis identified 191 significantly altered peptides in severely injured patients. A consistent increase in the abundance of peptides from A1AT, AHSG, and HBA1 was observed, while peptides derived from PIGR and UROM were consistently decreased. …”
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Protocol for a prospective, observational, hospital-based multicentre study of nosocomial SARS-CoV-2 transmission: NOSO-COR Project by Hubert P Endtz, Mitra Saadatian-Elahi, Valentina Picot, Laetitia Hénaff, Florence K Pradel, Vanessa Escuret, Cédric Dananché, Christelle Elias

“…In France, mortality rate in the general population was approximately 10% and could reach higher levels at the hospital. In the current context of high incidence rates of SARS-CoV-2 in the community, a significant increase in the rate of nosocomial transmission is expected. …”
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Specimens and culture media for the laboratory diagnosis of typhoid fever by John Wain, To Song Diep, Phan Van Be Bay, Amanda L. Walsh, Ha Vinh, Nguyen M. Duong, Vo Anh Ho, Tran T. Hien, Jeremy Farrar, Nicholas J. White, Christopher M. Parry, Nicholas P. J. Day

“…For 263 positive stool cultures, selenite F and selenite mannitol performed equally well and culturing 2 g rather than 1g increased the isolation rate by 10.5%. Conclusions: For the diagnosis of typhoid fever by blood culture the medium should be a rich nutrient broth containing a lysing agent. …”
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Density matrix emulation of quantum recurrent neural networks for multivariate time series prediction by J D Viqueira, D Faílde, M M Juane, A Gómez, D Mera

“…However, the effective implementation of some QRNN models is limited by the need for mid-circuit measurements. Those increase the requirements for quantum hardware, which in the current noisy intermediate-scale quantum era does not allow reliable computations. …”
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Intelligent Monitoring and Treatment System of Heavy Metal Contaminated Soil Based on Artificial Bee Colony Algorithm and Edge Computing Nanotechnology by Ke Hu, Dongdong Li, Xiaolei Cui, Donghua Hu, Junliang Chen, Shaopeng Zhuan, Hao Chang, Yaping Zhang, Tingting An, Juqin Zhang

“…Abstract The CGABC algorithm improves the convergence speed of the algorithm by crossing the solution generated by the neighborhood search of bees with the current global optimal solution. By selecting reasonable cross-operation coefficients to balance the algorithm's global optimization ability and local search ability, and adding random interference terms to increase population diversity. …”
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National Museums and Their Societal Roles: A Case Study of Finland and Japan by Shikoh Shiraiwa

“…In this article I focuses on museum professionals in Finnish and Japanese national museums within the context of current social and cultural sustainability discourses, who face an increased responsibility to democratize museum narratives and acknowledge inconvenient histories and the ongoing coloniality of the institutions and repatriation of cultural insignia. …”
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Making temporary homes by Marjolein Overtoom

“…Decreasing the housing shortage by building new houses takes time, while people need to find a space to live now. …”
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Metabolizable energy and digestible nutrient values of protease-supplemented field pea for broiler chicken by Tofuko A. Woyengo, Anna Rogiewicz, Robert Patterson

“…Results indicate that the protease product used in the current study marginally reduced the SID of AA for both SBM and field pea. …”
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Indian Himalayan Arabidopsis thaliana population reflects deep history and might be the source of species expansion in the eastern edge by Akanksha Singh, Ashwani Kumar Verma, Abhinandan Mani Tripathi, Parneeta Mishra, Sumit Kumar Bag, Sivasubramanian Rajarammohan, Sribash Roy

“…The genetic diversity of Indian populations was found to decrease towards east and west of its peripheral region. …”
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“Hold the retractor, that’s it?” – A retrospective longitudinal evaluation-study of the surgical and the elective tertial in the practical year by Junga, Anna, Görlich, Dennis, Scherzer, Sönke, Schwarz, Meike, Schulze, Henriette, Marschall, Bernhard, Becker, Jan Carl

“…Introduction: In the context of the shortage of physicians, the practical year is an important component in the acquisition of future medical talent. …”
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Evaluation of pre-exposure vaccine effectiveness against mpox during the 2022–2023 mpox outbreak in the Madrid region (Spain): a test-negative design by José Francisco Barbas del Buey, Jesús Íñigo Martínez, Marcos Alonso García, Andrés Aragón Peña, Laura Montero Morales, Araceli Arce Arnáez

“…Introduction An appropriate vaccination approach is critical to control the current outbreak of mpox but there is little research providing information on its effectiveness, particularly under circumstances of limited vaccine availability.Methods Pre-exposure vaccination campaign in the Madrid region, with the modified vaccinia Ankara-Bavarian Nordic was indicated in the risk groups from 18 July 2022.To evaluate the vaccine effectiveness (VE) of a dose of third-generation smallpox vaccine against mpox in the context of pre-exposure prophylaxis, a population-based indirect cohort study (Broome method) also known as test-negative design (TND) was conducted in the Madrid region (6 751 251 inhabitants). …”
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Sectoral investments to achieve water, energy and land SDG under climate change uncertainty by Adriano Vinca, Muhammad Awais, Edward Byers, Volker Krey, Keywan Riahi

“…Developing countries in Asia and sub-Saharan Africa will need to increase their spending by 10%–30%, compared to current trends, to meet their SDGs for water. …”
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Presenting the agility model of the organization in order to improve the productivity of human resources by Asie Mohmedi, Rashid Zolfaghari, Mahsa Gholam hossein zadeh

“…In terms of purpose, the current research is applicable in the quantitative part, fundamental-exploratory in the qualitative part, and mixed (qualitative-quantitative) in terms of implementation. …”
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Larvul Ngabal Law as A Regulation in Marine Resources Management In Kei Islands, Southeast Maluku Regency by La Ode Angga, Barzah Latupono, Ahmad Yani Renuat, Rini Atbar

“…Results of the Research: The existence or existence of law Larvul Ngabal Currently, it is increasingly existing, this can be seen from the increasingly advanced society of Southeast Maluku and have the same feelings in a group, where they stay in one place because they come from from the same genealogy or descent. …”
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Value foundations of experiencing stress and adaptation of students: Cross-cultural study by E. I. Koltunov, V. G. Gryazeva-Dobshinskaya, Ya. A. Dmitrieva, N. V. Markina, J. Zhi, E. S. Naboichenko

“…Present work is dedicated to an urgent problem that has emerged as a result of a global trend – an increase in the number of young people moving to other countries in search for a higher education, which often leads to stress during the process of cultural adaptation.In the current research, the authors conducted a comparative analysis of the normative and individual values of students from China and Russia, studying at the Russian university. …”
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Proper performance of duties that ensure the adversarial nature of criminal proceedings in Russia by E. N. Petukhov, M. A. Neymark

“…A problematic situation in criminal proceedings is revealed in the form of imperfection of the means intended to achieve his appointment in the context of the implementation of the adversarial legal regime. …”
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Pedagogical science in Russia: Much history, no strategies by I. P. Smirnov

“…It is well known that when scientific successes are modest, history, an endless exploration of the past instead of a strategic analysis of the future, is used.The aim of the present article was a critical discussion of the subject, goals and content of modern pedagogical research, reasons for scientists’ focus on historical context of education, their isolation from the current situation and the strategy for its further development.Methodology and research methods. …”
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Modeling marine microplastic emissions in Life Cycle Assessment: characterization factors for biodegradable polymers and their application in a textile case study by Felicitas Pellengahr, Elena Corella-Puertas, Elena Corella-Puertas, Valérie Mattelin, Nadim Saadi, Francesca Bertella, Anne-Marie Boulay, Yvonne van der Meer

“…However, current LCA modeling is not considering the potential impacts of plastic emissions on the biosphere. …”
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Psychological mechanisms of destructive manipulation and strategies for preventing digital fraud by M.I. Rozenova, A.S. Ognev, E.V. Likhacheva

“… <p style="text-align: justify;"><strong>Context and relevance</strong>. The complex and international nature of the economic, social, moral and psychological damage caused by digital fraud, and its size, determines the search for ways to counteract and improve the safety of human activities in the digital environment. …”
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