Tissue Specific Effects of Chronic Sustained Hypoxia on Oxidative Stress: Role of Cilnidipine, a Dual L/N Type Calcium Channel Blocker by Shrilaxmi Bagali, Akram Naikwadi, Kusal K. Das

“…Background: Blood flow, metabolic rate and oxygen requirements of an organ guide the extent of oxidative stress experienced by any tissue in response to chronic hypoxia. Currently cilnidipine is used in the management of hypertension and its antioxidant actions are gaining wide interest. …”
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Professional pharmacy Services' outcomes performance measurement: A narrative review by Lígia Reis, João Gregório

“…To do so is important to understand which outcome performance indicators are currently being used and how added value is proven. …”
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Counting animals in orthomosaics from aerial imagery: Challenges and future directions by Ismael V. Brack, Camila Ferrara, German Forero‐Medina, Enrique Domic‐Rivadeneira, Omar Torrico, Kevin Thomas Wanovich, Benjamin Wilkinson, Denis Valle

“…Researchers should carefully consider if using orthomosaics is really needed for surveying wildlife. Currently, there is a lack of methods to prevent these errors from arising and to explicitly accommodate them in modelling approaches. …”
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Development of a Best Practice Guide to Optimise the Reporting of Patient Reported Measures by Clinical Quality Registries for Quality Improvement Purposes by Rasa Ruseckaite, Chethana Mudunna, Ilana Ackerman, Belinda Gabbe, Susannah Ahern

“…A preliminary BPG was refined during the workshop discussions. Conclusion: An increasing number of CQRs use PRMs to enhance QI reporting, however there are no published guidelines currently to support this. …”
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Acute Effects of a Single-Bout Session of High-Intensity Functional Training and Moderate-Intensity Functional Training on Cognitive Functions, Anxiety, and Stress in Healthy Adult... by Francisco José Trujillo-Gutiérrez, José López-Aguilar, Francisco Álvarez-Salvago, Honorato Morente-Oria, José Daniel Jiménez-García

“…Background: Currently, it has been observed that a fast-paced lifestyle, along with factors such as work pressure and economic and political uncertainty, among others, negatively impacts cognitive functions and increases levels of anxiety and stress in the population. …”
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Conceptualización de los medios sociales: oportunidades para la gestión del deporte (Conceptualisation of Social Media: opportunities for Sport Management) by Samuel López-Carril, Miguel Villamón Herrera, Vicente Añó Sanz

“…Social Media is a phenomenon that is changing the way that people communicate and relate among others, with many millions of users around the world. In the context of Sport Management, Social Media currently is playing a role increasingly more relevant in the day to day of clubs, athletes, federations, companies, researchers, etc. …”
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Effect of Self-Care Strategies on Health Outcomes of Patients with Hepatocellular Carcinoma by Hala Sheta, Nehal Abo El-Fadl

“… Context: Hepatocellular carcinoma is the prevailing form of primary liver cancer among adults and currently ranks as the primary cause of mortality in cirrhosis individuals. …”
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Identifying Patient-Reported Care Experiences in Free-Text Survey Comments: Topic Modeling Study by Brian Steele, Paul Fairie, Kyle Kemp, Adam G D'Souza, Matthias Wilms, Maria Jose Santana

“…Results are discussed in the context of person-centered care, patient safety, and health care quality improvement. …”
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Anesthetic problems in concomitant systemic lupus erythematosus (literature review) by O.V. Kravets, V.V. Yekhalov, V.V. Gorbuntsov

“…SLE is a very complex systemic autoimmune disease that presents major challenges in the surgical context; in the field of anesthesia, such patients should always be considered at higher risk. …”
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Examining interprofessional collaboration in oncogenetic service delivery models for hereditary cancers: a scoping review protocol by Maude Laberge, Jason Robert Guertin, Hermann Nabi, Karine Bouchard, Michel Dorval, Maria Eugenia Espinoza Moya, Julie Lapointe

“…Introduction In a context of limited genetic specialists, collaborative models have been proposed to ensure timely access to high quality oncogenetic services for individuals with inherited cancer susceptibility. …”
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The role of judicial authorities in criminal proceedings for political crimes in the Stalinist period: modern historiography by Alexander Ya. Kodintsev

“…A number of works on the history of the judicial authorities contain sections on the application of the rules of judicial procedure to political crimes. Currently, PhD theses, covering an increasing number of regions of Russia, are being defended actively. …”
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Time to treat the climate and nature crisis as one indivisible global health emergency by Kamran Abbasi, Parveen Ali, Virginia Barbour, Thomas Benfield, Kirsten Bibbins-Domingo, Stephen Hancocks, Richard Horton, Laurie Laybourn-Langton, Robert Mash, Peush Sahni, Wadeia Mohammad Sharief, Paul Yonga, Chris Zielinski

“…Fish provide more than half of dietary protein in many African, South Asian and small island nations, but ocean acidification has reduced the quality and quantity of seafood.16 Changes in land use have forced tens of thousands of species into closer contact, increasing the exchange of pathogens and the emergence of new diseases and pandemics.17 People losing contact with the natural environment and the declining loss in biodiversity have both been linked to increases in non-communicable, autoimmune, and inflammatory diseases and metabolic, allergic and neuropsychiatric disorders.10,18  For Indigenous people, caring for and connecting with nature is especially important for their health.19 Nature has also been an important source of medicines, and thus reduced diversity also constrains the discovery of new medicines. …”
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A comprehensive review of methodologies and application to use the real-world data and analytics platform TriNetX by Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Matthew Anson, Matthew Anson, Henner Zirpel, Diamant Thaci, Henning Olbrich, Katja Bieber, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Astrid Dempfle, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Sizheng S. Zhao, Uazman Alam, Uazman Alam, Uazman Alam

“…TriNetX’s federated network architecture allows real-time, privacy-compliant data access, significantly enhancing the ability to conduct retrospective studies and refine clinical trial designs. With access to currently over 150 million EHRs, TriNetX has proven particularly effective in filling gaps left by RCTs, especially in the context of rare diseases, rare endpoints, and diverse patient populations. …”
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Where Has All the R-process Gone? Timescales for Gamma-Ray Burst Kilonovae to Enrich Their Host Galaxies by Anya E. Nugent, Alexander P. Ji, Wen-fai Fong, Hilay Shah, Freeke van de Voort

“…Neutron star (NS) mergers are currently the only observed source of r -process production in the Universe. …”
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The limited contribution of local food policies in food resilience: The case of French Territorial Food Projects by Margaux Alarcon, Nathalie Corade

“…The concept of resilience is currently increasingly used to investigate how food systems operate. …”
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Implementing nature walking groups in mental health services as a transdiagnostic approach to promote recovery: a study ​protocol for a non-randomised trial by Nicole Snowdon, Zubair Ahmed Ratan, Katarzyna Olcon, Peter Destry, Julaine Allan

“…Abstract Background Australia is currently facing substantial challenges due to the increasing prevalence of mental health disorders, which pose significant burden on the healthcare system. …”
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Psychological Features of 7-8 Grade Students Interaction with Hypertext: A Theoretical and Experimental Study Using an Eye Tracker by N.A. Borisenko, A.A. Ganicheva, K.V. Mironova, S.V. Shishkova

“… <p><strong>Context and relevance.</strong> Currently, hypertext systems are beginning to play an increasingly important role both in the media and in the educational process. …”
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Pedagogical Culture of Teachers at Technical Universities for Safe Educational Process During the War in Ukraine. by Natalia Tverdokhliebova, Nataliіa Yevtushenko

“… The entire education system is currently undergoing structural changes, which are reflected in the increased use of digital and distance learning technologies. …”
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Design and Synthesis of Bis-Chalcones as Curcumin Simplified Analogs and Assessment of Their Antiproliferative Activities Against Human Lung Cancer Cells and <i>Trypanosoma cruzi</... by Gabriela Alves de Souza, Lorrane de Souza Chaves, Afonso Santine M. M. Velez, Jorge Lucas F. Lacerda, Paulo Pitasse-Santos, Jayane Clys Conceição dos Santos, Otávio Augusto Chaves, Carlos Serpa, Raphael do Carmo Valente, Leonardo Marques da Fonseca, Marcos André Rodrigues da Costa Santos, Jhenifer Santos dos Reis, Carlos Antônio do Nascimento Santos, Lucia Mendonça-Previato, Jose Osvaldo Previato, Celio Geraldo Freire-de-Lima, Debora Decoté-Ricardo, Leonardo Freire-de-Lima, Marco Edilson Freire de Lima

“…<b>Background: </b>Anticancer therapies represent the primary treatment option for a significant number of cancer patients globally; however, many of these treatments are associated with severe side effects as they target molecular structures present in both cancerous and healthy cells. In a similar context, the treatment of Chagas disease, a neglected tropical illness, is hindered by the high toxicity of the currently available drugs. …”
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Understanding data and information needs for palliative cancer care to inform digital health intervention development in Nigeria, Uganda and Zimbabwe: protocol for a multicountry q... by Richard Harding, Bassey Ebenso, Adlight Dandadzi, Eve Namisango, Kehinde Okunade, Kennedy Bashan Nkhoma, Omolola Salako, David Akeju, Olaitan Soyannwo, Elizabeth Namukwaya, Elizabeth Nabirye, Lovemore Mupaza, Emmanuel Luyirika, Henry Ddungu, Z Mike Chirenje, Michael I Bennett, Matthew J Allsop

“…However, there is currently a lack of any theoretical underpinning or data to understand stakeholder drivers for digital health components in this context. …”
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