The Main Directions of Improving the Methodology for the Application of Advanced Information and Communication Technologies in the Statistical Activities of the Republic of Uzbekis... by I. E. Zhukovskaya

“…This article presents the main directions of improving the methodology of using advanced information and communication technologies in the statistical industry of the Republic of Uzbekistan in the context of the digitalization of the economy. In particular, it is shown that modern ICTs have a huge potential for global competitiveness and contribute to the growth of the country's economy.Currently, in the statistical industry of the Republic of Uzbekistan, a large number of statistical calculations and forecasts are carried out on the basis of the use of the advanced ICT, there is experience in organizing interaction between information systems (IS), operating in the State Committee of the Republic of Uzbekistan on Statistics (Goskomstat), however, in preparation for population census and the implementation of the National Program “Digital Uzbekistan – 2030”, there is a need to develop new methodological solutions, technologies, software products, innovative mechanisms for collecting, processing and providing reporting information to various categories of users based on the use of the advanced ICT.Purpose. …”
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Antiviral efficacy of fluoxetine in early symptomatic COVID-19: an open-label, randomised, controlled, adaptive platform trial (PLATCOV)Research in context by Podjanee Jittamala, Simon Boyd, William H.K. Schilling, James A. Watson, Thundon Ngamprasertchai, Tanaya Siripoon, Viravarn Luvira, Elizabeth M. Batty, Phrutsamon Wongnak, Lisia M. Esper, Pedro J. Almeida, Cintia Cruz, Fernando R. Ascencao, Renato S. Aguiar, Najia K. Ghanchi, James J. Callery, Shivani Singh, Varaporn Kruabkontho, Thatsanun Ngernseng, Jaruwan Tubprasert, Wanassanan Madmanee, Kanokon Suwannasin, Amornrat Promsongsil, Borimas Hanboonkunupakarn, Kittiyod Poovorawan, Manus Potaporn, Attasit Srisubat, Bootsakorn Loharjun, Walter R.J. Taylor, Farah Qamar, Abdul Momin Kazi, M. Asim Beg, Danoy Chommanam, Sisouphanh Vidhamaly, Kesinee Chotivanich, Mallika Imwong, Sasithon Pukrittayakamee, Arjen M. Dondorp, Nicholas P.J. Day, Mauro M. Teixeira, Watcharapong Piyaphanee, Weerapong Phumratanaprapin, Nicholas J. White

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An interpretable machine learning tool for in-home monitoring of agitation episodes in people living with dementia: a proof-of-concept studyResearch in context by Marirena Bafaloukou, Ann-Kathrin Schalkamp, Nan Fletcher-Lloyd, Alex Capstick, Chloe Walsh, Cynthia Sandor, Samaneh Kouchaki, Ramin Nilforooshan, Payam Barnaghi

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HVDC transformer insulation system: Present research, trends, challenges, and prospects by Muhammad Rafiq, Muhammad Shafique

“…High-voltage direct current (HVDC) has attained significant consideration owing to numerous valuable characteristics, for instance, lowest transmission losses, improved stability, and control operation. …”
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Increasing our knowledge about the epidemiology of Helicobacter pylori in Nunavik’s Inuit population (Québec, Canada) using Qanuilirpitaa? 2017 cross-sectional survey by Julie Ducrocq, Benoit Lévesque, Gaston De Serres, Véronique Boiteau, Cedric P. Yansouni, Jean-François Proulx, Denis Talbot

“…Despite current regional guidelines targeting high risk individuals in the context of high prevalence, Nunavik’s health authorities must remain vigilant by following gastric cancer incidence and the rapid evolution of guidelines, while considering local realities.…”
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Low drying temperature has negligible impact but defatting increases in vitro rumen digestibility of insect meals, with minor changes on fatty acid biohydrogenation by Manuela Renna, Mauro Coppa, Carola Lussiana, Aline Le Morvan, Laura Gasco, Lara Rastello, Jonas Claeys, Gaëlle Maxin

“…Abstract Background Insect meals have been identified as innovative and sustainable feedstuffs that could be used in ruminant nutrition. However, current research on the effects that their processing may have on rumen digestibility and fatty acid (FA) biohydrogenation is scant. …”
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Progress towards the UNAIDS 2030 HIV prevention target in New South Wales, Australia: a population-based studyResearch in context by Phillip Keen, Steven J. Nigro, Curtis Chan, Benjamin R. Bavinton, Htein Linn Aung, Martin Holt, Rebecca Guy, Janaki Amin, Timothy R. Broady, Jane Costello, Anthony D. Kelleher, Carla Treloar, Rick Varma, Matthew Vaughan, Valerie Delpech, Andrew E. Grulich

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Short Interfering RNA Directed against the SLUG Gene Increases Cell Death Induction in Human Melanoma Cell Lines Exposed to Cisplatin and Fotemustine by Ivan Vannini, Massimiliano Bonafe, Anna Tesei, Marco Rosetti, Francesco Fabbri, Gianluca Storci, Paola Ulivi, Giovanni Brigliadori, Dino Amadori, Wainer Zoli

“…Background: Melanoma remains largely resistant to currently available chemotherapy, and new strategies have been proposed to flank standardized therapeutic protocols in an effort to improve efficacy. …”
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The Concentration-dependent Investigation of the Toxic Effects of the Anorectic Agent Sibutramine on the Electrical Activity of the Cardiomyocytes in Metabolic Syndrome Rat Heart by Yusuf Olgar, Feyza Alyu, Yusuf Öztürk, Belma Turan

“…All patch-clamp experiments were performed in whole-cell mode, but action potentials were recorded in current-clamp configuration and voltage-gated K+-channel currents in voltage-clamp configuration from freshly isolated MetS cardiomyocytes. …”
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Influence of ambient temperature on the safety of live poultry during automobile transportation by M. V. Gryaznov, P. P. Zhuravskiy, E. A. Timofeev

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Evaluation of Temporal Changes in Evapotranspiration and Crop Water Requirements in the Context of Changing Climate: Case Study of the Northern Bucharest–Ilfov Development Region,... by Florentina Iuliana Mincu, Daniel Constantin Diaconu, Dana Maria Oprea Constantin, Daniel Peptenatu

“…The methodology used highlights this fact, showing that major changes are needed in the choice of crop schemes and future technological processes in the current context of climate change. The current results of the study, conducted over a period of 30 years (1991–2020), showed that the climatic, land use and economic changes in the study area have led to a decrease in evapotranspiration and crop water requirements due to the amounts of precipitation that can provide for the water needs of strawberry, sunflower and pea crops. …”
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The epidemiology of bacterial meningitis in the United States during 2008–2023: an analysis of active, laboratory, population-based, multistate surveillance dataResearch in context... by Namrata Prasad, Miwako Kobayashi, Jennifer P. Collins, Amy B. Rubis, Gordana Derado, Miranda J. Delahoy, Daniel C. Payne, Lesley McGee, Sopio Chochua, Henju Marjuki, Lucy A. McNamara, LeAnne M. Fox, Arthur Reingold, Megan Barnes, Susan Petit, Monica M. Farley, Lee H. Harrison, Ruth Lynfield, Jessica Houston, Bridget J. Anderson, Ann Thomas, Keipp H. Talbot, William Schaffner, Adam L. Cohen, Stephanie J. Schrag, Melissa Arvay

“…During 2022–2023, incidence increased to 1.0, driven by increases in S. pneumoniae and H. influenzae meningitis. …”
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TssI2-TsiI2 of Vibrio fluvialis VflT6SS2 delivers pesticin domain-containing periplasmic toxin and cognate immunity that modulates bacterial competitiveness by Yuanming Huang, Yu Han, Zhenpeng Li, Xiaorui Li, Zhe Li, Ping Liu, Xiaoshu Liu, Qian Cheng, Fenxia Fan, Biao Kan, Weili Liang

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Current State And Trends In The Incidence Of Chronic Kidney Disease Among Adult Population And Opportunities For Its Prevention And Treatment In Moscow Healthcare Organizations by O. N. Kotenko, V. N. Vasina, A. Y. Brazhnikov, V. M. Kuraeva

“…Introduction. Currently, the incidence of kidney diseases among adult population is growing. …”
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Impact of strategic public health interventions to reduce tuberculosis incidence in Brazil: a Bayesian structural time-series scenario analysisResearch in context by Klauss Villalva-Serra, Beatriz Barreto-Duarte, Moreno M. Rodrigues, Artur T.L. Queiroz, Leonardo Martinez, Julio Croda, Valeria C. Rolla, Afrânio L. Kritski, Marcelo Cordeiro-Santos, Timothy R. Sterling, Mariana Araújo-Pereira, Bruno B. Andrade

“…Additional reductions were seen with increased coverage of DOT, TPT adherence, and contact investigation rates (−14.4 [−13 to −16.2]), and by combining these with efforts to reduce TB cases among vulnerable populations (−23.6 [−26.3 to −41.4]), potentially lowering incidence to 18.5 [7.8–28.4] per 100,000, though still above WHO targets. …”
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Antiretroviral drug class and anaemia risk in the current treatment era among people living with HIV in the USA: a clinical cohort study by Richard D Moore, Kenneth Mayer, Greer Burkholder, Susan R Heckbert, Barbara N Harding, Bridget M Whitney, Robin M Nance, Heidi M Crane, W Christopher Mathews, Joseph J Eron, Peter W Hunt, Paul Volberding, Michael S Saag, Mari M Kitahata, Joseph A C Delaney

“…Objective Anaemia is common among people living with HIV (PLWH) and has been associated with certain, often older, antiretroviral medications. Information on current antiretroviral therapy (ART) and anaemia is limited. …”
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MFFCI–YOLOv8: A Lightweight Remote Sensing Object Detection Network Based on Multiscale Features Fusion and Context Information by Sheng Xu, Lin Song, Junru Yin, Qiqiang Chen, Tianming Zhan, Wei Huang

“…Most current researches primarily focus on improving experimental accuracy using large models, often neglecting the deployment challenges. …”
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Mapping context of sedentary behaviour in older adults who are prefrail and frail: an analysis of secondary outcomes from a longitudinal study (MAPS-B) by Rong Zheng, Jonathan D Adachi, Alexandra Papaioannou, George Ioannidis, Alexander Rabinovich, Isabel B Rodrigues, Mayank Kalra, Dylan Kobsar, Steven R Bray, Qiyin Fang

“…Although there were no differences in sedentary time between seasons, we found a significant decrease in step count in winter (1190 fewer steps, 95% CI −2228 to −153 steps). …”
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An Analysis of Supply Chain Macro-Strategies in the Context of Industry 4.0 with a System Dynamics Approach (The Case of: Iran's Steel Supply Chain) by Sima Motallebi, Mostafa Zandieh, Akbar Alem Tabriz

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Pharmacoeconomic rationale for switching patients with rheumatic diseases from original biologic disease-modifying antirheumatic drugs to biosimilars in context of the Russian heal... by A. Yu Kulikov, V. G. Serpik, A. M. Lila

“…At the same time, in the context of budgetary constraints, switching to biosimilars remains perhaps the only available strategy for increasing the coverage of patients with innovative drugs. …”
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