Human immunodeficiency virus prevention and testing strategies among men who have sex with men in the UK: the PANTHEON research programme including the SELPHI RCT by Janey Sewell, T Charles Witzel, David Dunn, Fiona Lampe, Fiona Burns, Peter Weatherburn, Sheena McCormack, Leanne McCabe, Alec Miners, Valentina Cambiano, Roger Pebody, Roy Trevelion, Nadia Hanum, Andrew Phillips, Alison Rodger

“…Modelling suggested that provision of oral tenofovir/emtricitabine pre-exposure prophylaxis increased human immunodeficiency virus testing, with anti-retroviral therapy initiation at diagnosis, and reductions in the level of condom-less sex, that each played an important role in decreasing human immunodeficiency virus incidence among men who have sex with men, and that the current human immunodeficiency virus incidence would have been double what it is if any one of them had not occurred. …”
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‘It was a joint plan we worked out together’. How the I-WOTCH programme enabled people with chronic non-malignant pain to taper their opioids: a process evaluation by Martin Underwood, Kate Seers, Charles Abraham, Harbinder Kaur Sandhu, Vivien P Nichols, Sam Eldabe, Alleyne Sharisse, Balasubramanian Shyam, Betteley Lauren, Booth Katie, Carnes Dawn, D Furlan Andrea, Haywood Kirstie, Iglesias Urrutia C Paola, Lall Ranjit, Manca Andrea, Mistry Dipesh, Noyes Jennifer, Rahman Anisur, Shaw Jane, KY Tang Nicole, Taylor Stephanie, Tysall Colin, Underwood Martin, J Withers Emma

“…Background The Improving the Wellbeing of people with Opioid Treated CHronic pain (I-WOTCH) randomised controlled trial found that a group-based educational intervention to support people using strong opioids for chronic non-malignant pain helped a significant proportion of people to stop or decrease opioid use with no increase in pain-related disability. …”
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Economic Analysis of Global CO₂ Emissions and Energy Consumption Based on the World Kaya Identity by Alina Yakymchuk, Simone Maxand, Anna Lewandowska

“…Thus, an unexpected increase in the population likely does not have short-term effects on CO₂ emissions, and the responses to GDPpc and energy intensity both decrease after some periods, while the shock in carbon intensity shows a significant effect even after 10 years. …”
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Wisdom of the Established Pattern by Joel Janhonen

“…According to their example, if someone is opposed to increasing as well as decreasing the average human intelligence, they need a good reason for why the current level is optimal. …”
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A Framework for Sustainability Performance Measurement Through Process Mining: Integration of GRI Metrics in Operational Processes by Ourania Areta Hiziroglu, Onur Dogan

“…Organizations face significant challenges in measuring and enhancing sustainability performance across complex operational processes. Current assessment methods frequently lack granularity, real-time capability, and integration with operational data. …”
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Political Dimensions of International Sports and Economic Policies for AI Adoption by Aminova Aziza, Umurkulova Dilrabo, Komilov Jahongir

“…The paper attempts to move forward research in AI adoption from theoretical, empirical, and policy-driven contexts to emerging methodological frameworks that address current challenges in governance and strategic implementation. …”
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Extended reality in anesthesia: a narrative review by Sung Hee Han, Kristen L Kiroff, Sakura Kinjo

“…This review aims to introduce the current literature on XR utilization to help anesthesiologists adopt this technology in education and clinical practice. …”
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A Systematic Literature Review of Cross-Cultural Studies on Interior Perception by Ayşen Özkan, Türkan Sultan Yaşar Ismail

“…Interior spaces can be seen as one of the main surroundings for people, especially in the context of the current century urban context we live in. …”
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Brand authenticity influence on young adults’ luxury sneakers brand preference: the mediating role of brand image by Neo Ligaraba, Joy Cheng, Nompumelelo Fortunate Ndungwane, Brighton Nyagadza

“…The same model development for the current study can be applied in other geographical zones and in different contexts to prove its generalisability. …”
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Big oil and climate change: An ecolinguistic perspective by Richard John Alexander, Douglas Mark Ponton

“…Five years later, that challenge has become even greater due to a continued increase in greenhouse gas emissions. The pace and scale of what has been done so far, and current plans, are insufficient to tackle climate change.” …”
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A systematic review of sexual health, knowledge, and behavior in Autism Spectrum Disorder by Mahtab Motamed, Arman Hajikarim-Hamedani, Arghavan Fakhrian, Javad Alaghband-rad

“…Further research should address current gaps, especially regarding non-Western contexts and individuals with co-occurring intellectual disabilities or gender diversity, to improve support and understanding.…”
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The future of education: Importance of ethical frameworks and cultural sensitivity by Baltezarević Borivoje V.

“…With the advent of artificial intelligence (AI) and advanced platforms such as ChatGPT, we are witnessing profound changes in the educational context that are increasingly becoming the focus of current scientific research and discourse. …”
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Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4 by Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao

“…Furthermore, MUC4 overexpression in the context of HIF-1α knockout was positively correlated with increased ECM protein expression and TIF. …”
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Effects of coriander components linalool and geranyl acetate on stress-related neuroendocrine and behavioral measures in adult zebrafish (Danio rerio) by Maureen L. Petrunich-Rutherford

“…However, it is currently unclear how the individual phytochemical components of coriander regulate anxiety-like behavior and stress axis activity. …”
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Angiotensin-(1-7) protective effects in neurocognitive disorders: molecular mechanisms to therapeutic implications by Lillia C. Lucas, Katherine D. Kimbark, Victoria L. Vernail, Yuval Silberman, Amy C. Arnold

“…Current treatments for neurocognitive disorders have limited efficacy and typically focus on symptom attenuation rather than targeting intrinsic pathophysiology. …”
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Playing towards Motivation: Gamification and University Students in Physical Activity! by Victor Javier Sotos-Martinez, Salvador Baena-Morales, Manuel Sanchez-De Miguel, Alberto Ferriz-Valero

“…There is currently concern about the decrease in physical activity participation among university students. …”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…CE-MS peptidome analysis identified 191 significantly altered peptides in severely injured patients. A consistent increase in the abundance of peptides from A1AT, AHSG, and HBA1 was observed, while peptides derived from PIGR and UROM were consistently decreased. …”
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Sexual Crimes in Metaverse: New Frontiers in Forensic Psychology and Legal Challenges by Giulia Melis, Merylin Monaro

“…While digital threats such as the dissemination of pornographic material have long been recognized, behaviors like sexual harassment and assault have historically been addressed primarily within physical contexts. However, in Metaverse, the boundaries between virtual and physical harm are increasingly blurred, as illustrated by the first widely reported case of virtual rape in January 2024, involving the avatar of a young girl assaulted by other users in an immersive gaming environment. …”
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Registry-based surveillance of paediatric home respiratory support in Switzerland: methodology and initial findings by Sophie Guerin, Christian Bieli, Regula Corbelli, Thomas Ferry, Miriam Giaranna, Matthias Horn, Silvia Miano, Nicolas Regamey, Daniel Trachsel, Sylvain Blanchon

“…Analysis of the first year’s data in the SwissPedHRS registry showed a sixfold increase in prevalence since 2001. It also highlighted a larger spectrum of underlying medical conditions and types of sleep-disordered breathing leading to home respiratory support and important changes in home respiratory support modalities, with decreased invasive and increased non-invasive respiratory support and decreased BPAP and increased CPAP ventilation. …”
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Impact of metabolic-associated fatty liver disease on the cholesterol efflux capacity of high-density lipoproteins in adolescents with type 2 diabetes by José Antonio Orozco Morales, José Antonio Orozco Morales, Aída Xochitl Medina Urrutia, Margarita Torres Tamayo, Margarita Torres Tamayo, Juan Reyes Barrera, Esteban Jorge Galarza, Juan Gabriel Juárez Rojas, Pilar Dies Suarez, Nahum Méndez Sánchez, Nahum Méndez Sánchez, Luis Enrique Díaz Orozco, Luis Enrique Díaz Orozco, Lubia Velázquez-López, Patricia Medina Bravo, Patricia Medina Bravo

“…In the population with DM2 and MAFLD, we did not observe a decrease in CEC. Initially we found a slight elevation of CEC in adolescents with DM2, however, with the increase in liver fat, a little decrease is observed, which could explain a probable metabolic phenomenon, since the physicochemical composition and distribution of the particles is associated with the percentage of liver fat. …”
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