Promoting sound development of preterm infants in the name of developmental neuroscience: Beyond advanced life support and neuroprotection by Osuke Iwata, Sachiko Iwata, Yung-Chieh Lin, Shin Kato, Yuko Mizutani, Tadashi Hisano, Masahiro Kinoshita, Satoko Fukaya, Koya Kawase, Shinji Saitoh

“…Despite the increased survival opportunities for extremely preterm infants, their long-term cognitive outcomes remain poor, with increased incidence of cognitive impairments in childhood and reduced opportunities to attend higher education in young adulthood compared to their term-born peers. …”
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Challenges in modelling the impact of frost and heat stress on the yield of cool-season annual grain crops by Jonathan Richetti, Victor Oscar Sadras, Victor Oscar Sadras, Victor Oscar Sadras, Di He, Brenton Leske, Pengcheng Hu, Yacob Beletse, C. Mariano Cossani, C. Mariano Cossani, C. Mariano Cossani, Ha Nguyen, Bangyou Zheng, David Matthews Deery, M. Fernanda Dreccer, Jeremy Whish, Julianne Lilley

“…These temperature extremes are increasing in frequency and intensity due to climate change in many parts of the broadacre cropping regions globally, presenting challenges to food production. …”
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Vaping – A Beneficial Alternative to Traditional Cigarettes or an Unexplored Danger? by Paulina Błasiak, Aleksandra Ślusarska, Patryk Mikołajec, Barbara Bilecka, Jolanta Mędyk, Małgorzata Wirkijowska, Jakub Wirkijowski, Yauheniya Patarocha, Michał Rogulski, Ruslan Huk

“… The aim of this study is to assess the risks associated with e-cigarette use, particularly in the context of cardiovascular and respiratory health. …”
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Matching action to need: an analysis of Global Burden of Disease 2017 and population health data to focus adolescent health policy and actions in Myanmar by Karly I. Cini, Phone Myint Win, Zay Yar Swe, Kyu Kyu Than, Thin Mar Win, Ye Win Aung, Aye Aye Myint, Nisaa R. Wulan, Lia J. Burns, Elissa C. Kennedy, Kate L. Francis, Sanda, Su Mon Myat, Sithu Swe, Aung Ko Ko, Yadanar, Margaret Hellard, Chad L. Hughes, George C. Patton, Ali H. Mokdad, Peter S. Azzopardi

“…Conclusions: These results highlight the need to focus current efforts on addressing disease and mortality experienced by adolescents in Myanmar, with a specific focus on injury, mental health and non-communicable disease.…”
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Pregnancy-related acute kidney injury leads to hypertension, reduced kidney function and cognitive impairment in postpartum rats by Ashley Griffin, Jamie Szczepanski, Shauna-Kay Spencer, Shauna-Kay Spencer, Lucia Solis, Teylor Bowles, Reanna Robinson, Jan M. Williams, Patrick B. Kyle, Kedra Wallace, Kedra Wallace

“…Both hypertensive disorders of pregnancy and Acute Kidney Injury (AKI) outside the context of pregnancy have been associated with an increased risk of developing Chronic Kidney Disease (CKD) and cognitive impairment. …”
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Genome-Wide DNA Methylation Analysis during Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Yangyang Cao, Haoqing Yang, Luyuan Jin, Juan Du, Zhipeng Fan

“…We found that the majority of cytosines in a CpG context were methylated in induced BMSCs. Our results also revealed that, along with the induced osteogenic differentiation in BMSCs, the average genomic methylation levels and CpG methylation in transcriptional factor regions (TFs) were increased, the CpG methylation level of various genomic elements was mainly in the medium-high methylation section, and CpG methylation levels in the repeat element had highly methylated levels. …”
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Apple phenotyping using deep learning and 3D depth analysis: An experimental study on fruitlet sizing during early development by Giorgio Checola, Damiano Moser, Paolo Sonego, Cristian Iob, Franco Micheli, Pietro Franceschi

“…Current research in apple-growing focuses on collecting extensive biometric data to better understand physiological processes, improve orchard productivity and predict yields. …”
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Repetitive transcranial magnetic stimulation for the treatment of suicidality in opioid use disorder: a pilot feasibility randomized controlled trial by Victor M. Tang, Bernard Le Foll, Zafiris J. Daskalakis, An-Li Wang, Leslie Buckley, Daniel M. Blumberger, Daphne Voineskos

“…Conclusion We present the first data piloting a structural neuroimaging-guided, multi-session rTMS treatment course in outpatients with suicidality and OUD in the current North American context. Recruitment and retention were the main challenges given the highly unstable medical and psychosocial context of this patient population. …”
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HNF-1β alleviates podocyte injury in lupus nephritis by maintaining endoplasmic reticulum homeostasis by Jie Yu, Bing Guo, Fan Zhang, Miao Liu, Ying Xie, Hui-mei Zou, Yuan-yuan Ruan, Xiao-min An, Pei-lei Chen, Ying-qin Luo, Ming-jun Shi, Li-fen Xu

“…Objective The current study aims to elucidate the critical function of hepatocyte nuclear factor 1-beta (HNF1-β) in lupus nephritis (LN) by investigating its modulation of the Derlin-1/valosin-containing protein (VCP)/VCP-interacting membrane selenoprotein (VIMP) complex, endoplasmic reticulum (ER) stress and podocyte apoptosis.Methods In vitro and in vivo models of LN were established using glomerular podocytes treated with LN serum and MRL/lpr mice, respectively. …”
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C18:0 GM3 ganglioside’s efficacy in LPS-induced parkinsonism: neuroprotection, inflammatory inhibition and gliosis mitigation by Tsung-Ta Liu, Cheng-Tsung Liu, I-Hsun Li, Yu-Chieh Chu, Hao-Yuan Hung, Chuang-Hsin Chiu, Ta-Kai Chou, Shiao-Yun Li, Tin-An Wang, Jui-Hu Shih

“…Abstract Background Parkinson’s disease (PD) is an incurable neurological disorder, and current pharmacological therapies primarily address symptoms without halting disease progression. …”
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Low drying temperature has negligible impact but defatting increases in vitro rumen digestibility of insect meals, with minor changes on fatty acid biohydrogenation by Manuela Renna, Mauro Coppa, Carola Lussiana, Aline Le Morvan, Laura Gasco, Lara Rastello, Jonas Claeys, Gaëlle Maxin

“…Abstract Background Insect meals have been identified as innovative and sustainable feedstuffs that could be used in ruminant nutrition. However, current research on the effects that their processing may have on rumen digestibility and fatty acid (FA) biohydrogenation is scant. …”
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Quantitative characterization of adsorbed and free shale oil microscopic distribution based on nuclear magnetic resonance: a case study of Chang 7 member of Triassic Yanchang Forma... by Fei LIU, Jinliang DU, Lin SUN, Ruiliang GUO, Bofei HAO, Peng LIU

“…Adsorbed oil mainly exist in micropores (< 100 nm), and the amount of free oil in micropores, mesopores, and macropores sequentially decreases. Organic-matter-rich shale generally contain higher amount of free oil and lower amount of adsorbed oil due to the existence of hydrocarbon generation-induced microfractures and less developed organic pores. …”
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Efficacy and Safety of Various Intravenous Thrombolytics for Acute Ischemic Stroke (AIS) at Various Dosages: A Systematic Review and Network Meta-Analysis by Yibin Hu, Shengxian Wu, Haixuan Zhang, Kangfeng Wang, Lijuan Zhang, Yizheng Ma, He Li

“…Abstract Background Currently, there is limited evidence on the efficacy and safety of various thrombolytic drugs at different dosages for the treatment of acute ischemic stroke (AIS). …”
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A mixed-methods nutrition, water, sanitation and hygiene knowledge, attitudes, and practices survey of IDPs, returnees, and host community members in four counties of Jonglei state... by Lynn Lieberman Lawry, Rachel Gabor, Jacques Katele, Lazarus Baak Madut, Katina Sommers, David Manuel, Claire Nadolski, Mounir Lado, Tracey Perez Koehlmoos, William Clemmer

“…Improved flood resistant sources for clean water, clean covered water storage container distribution, improved sanitation, oral rehydration solution (ORS) and zinc distribution and education are necessary to decrease diarrheal rates.…”
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Digital currency: features of regulation in the Russian Federation by T. E. Rozhdestvenskaya, A. G. Guznov

“…The article examines the main approaches to the regulation of digital currencies, studies the phenomenon of digital currency itself, assesses the circumstances that aroused massive interest and enthusiasm for cryptocurrencies. An analysis of current positive legal material is presented, in particular, the approach to the regulation of digital currency contained in the Russian Federal Law of July 31, 2020 No. 259- FZ "On digital financial assets, digital currency and on amendments to certain legislative acts of the Russian Federation". …”
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EDUCATIONAL AUTONOMY AS AN IMPORTANT PREREQUISITE FOR THE FORMATION OF FUTURE PHDS’ RESEARCH COMPETENCE IN THE CONDITIONS OF POSTGRADUATE STUDIES by Oliinyk Iryna

“…The purpose of this research is to examine the concept of “learning autonomy” as an effective method of increasing the awareness of future PhD candidates in the process of developing research competence in terms of postgraduate studies. …”
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Absence of progression risk of chronic kidney disease in patients with urine protein-creatinine ratio below 500 mg/g: a cohort study with competing risk analysis by Jiang Bai, Lijuan Zhang, Jingkai Di, Wenyu Wang, Yawen Wu, Yun Zhou, Yun Zhou, Yun Zhou

“…The results of the Fine and Gray competing risk survival regression model showed the same trend.ConclusionIn patients with CKD and UPCR levels below 500 mg/g, there was no increased risk of CKD progression associated with the higher proteinuria levels.…”
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Validation of the Mild Behavioral Impairment Scale (MBI-S) for brief self-assessment of Mild Behavioral Impairment in people without dementia by Paula Hinkl, Elmar Graessel, Nicolas Rohleder, Peter Landendoerfer, Thomas Kuehlein, Natascha Lauer, Anna Pendergrass

“…It has high test economy and measures current neuropsychiatric symptoms and their intensity as a state criterion. …”
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Knowledge of Preconception Healthcare and Associated Factors: A Study among Mothers in Jinka Town, Southern Region, Ethiopia by Kassahun Fikadu Tesema, Tamirat Cheneka, Alemayehu Alemu, Mekonen Feyissa, Birhanu Birkaye, Hafiza Mohammed, Eleni Kidu, Getahun Wegaso, Biresaw Wasihun

“…Preconception healthcare is promising to improve the reproductive health status of women and couples if they receive care three months to two years before conception. In the current context of Ethiopia, however, preconception healthcare is overlooked in the continuum of care. …”
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Towards a sustainable rare disease and orphan drug ecosystem in Saudi Arabia: policy insights from a multi-stakeholder workshop by Ghada Mohammed Abozaid, Ghada Mohammed Abozaid, Hussain Abdulrahman Al-Omar, Abdulaziz Alrabiah, Asma AlMuaither, Amy Jayne McKnight

“…Through a series of presentations, educational sessions, and plenary discussions, participants examined the current landscape of RDs in SA, identified barriers to accessing ODs, and recommended strategies and initiatives to improve the accessibility, innovation, and sustainability of ODs.ResultsThe workshop highlighted key challenges recognized by a diverse group of 59 participants, including the absence of a national strategy, absent of local RDs and ODs definitions in the Saudi context, limited awareness and understanding of RDs among healthcare professionals, delayed diagnoses, scarcity of treatment and diagnosis centers for RDs, insufficient screening and prevention programs, regulatory hurdles in approving and importing ODs, and financial constraints. …”
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