Production and characterization of a promising microbial-derived lipase enzyme targeting BCL-2 gene expression in hepatocellular carcinoma by Amal M. Abo-Kamer, Ahmed A. Abdelaziz, Esraa S. Elkotb, Lamiaa A. Al-Madboly

“…Abstract Context and goal This study aimed to isolate and optimize a high-yield lipase-producing Pseudomonas aeruginosa strain from biological samples, enhance enzyme production through random mutagenesis, and evaluate its potential anticancer activity. …”
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Mapping and visualization of global research progress on autophagy in metabolic dysfunction-associated steatotic liver disease and metabolic syndrome: a bibliometric analysis (2009... by Xing Liu, Xiang Li

“…ObjectiveThis study aimed to delineate the current trends and hotspots in autophagy research related to metabolic syndrome (MetS) and metabolic dysfunction-associated steatotic liver disease (MASLD), with the aim of guiding future investigations in this area.MethodsThis study extracted research on autophagy in MetS and MASLD from the Web of Science Core Collection (WoSCC) database. …”
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Application and Development of Firefighting Technologies in Industrial Heritage: Experiences and Insights from Macau by Linsheng Huang, Ying Huang, Yashan Chen, Senyu Lou, Yile Chen, Mengyan Jia

“…The results show that (1) the fire protection of the industrial heritage of Macau has gone through a total of three phases: passive fire protection, transition of fire protection methods, and active fire protection, and the relied-upon fire protection technologies have been iterated and renewed continuously during this period. (2) When the fire load factors of industrial heritage increase, the fire vulnerability assessment substantially changes, and the center of gravity of heritage fire protection shifts from controlling the scope of disaster to reducing the fire risk. (3) The construction of a suitable and effective ecological model of fire protection technology can provide appropriate fire protection solutions for the preservation and reuse of Macau’s industrial heritage in a complex cultural context. …”
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Research on Unfair Competition in the Digital Economy: Innovation, Regulation, and Balancing Strategies by Kang Yuhao

“…Online unfair competition is on the rise, disrupting market order and violating consumer rights in the context of the fast developing digital economy. Therefore, the purpose of this essay is to investigate the nature and forms of unfair competition in the internet economy and how it affects innovation. …”
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The Catalog of Aquatic Mollusca (Bivalvia and Gastropoda) in the Limnology Museum of Çanakkale Onsekiz Mart University (COMULM) by Songül Biçer, Deniz Anıl Odabaşı, Buğra Öztürk

“…Objective: Natural History Museums are important organizations that increase the awareness of the public on biodiversity, nature, and its conservation. …”
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Why in the Modern World the Future is Replaced by the Past: is History Coming Back? by A. I. Filyushkin

“…In the last two or three decades, there has been a progressive increase in interest in history. Scientists see the reasons for this in the political situation, the growth of nationalist sentiments, and “memory wars.” …”
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LSTGINet: Local Attention Spatio-Temporal Graph Inference Network for Age Prediction by Yi Lei, Xin Wen, Yanrong Hao, Ruochen Cao, Chengxin Gao, Peng Wang, Yuanyuan Guo, Rui Cao

“…First, multi-scale temporal and spatial branches are used to increase the receptive field and model the age information simultaneously, achieving the perception of static correlation. …”
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Effect of Authentic Leadership Educational Program for Head Nurses on Staff Nurses' Organizational Commitment by Aziza Z. F. Ali, Ehsan S. S. Saad, Fadhah T. Alshammari

“… Context: Authentic leadership is required to build trust and achieving positive organizational outcomes. …”
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Socio-Economic Challenges for the Urban Ecosystem: Complex Model of Smart Tourism and Infrastructure by Gevorg Orbelyan

“…In order to fill important deficiencies in Yerevan’s current engineering and transportation infrastructure and increase the city's allure as a travel destination, this study aims to develop a new theoretical framework – the Comprehensive Smart Tourism and Infrastructure Model – specifically designed to address the challenges and opportunities unique to Yerevan's urban ecosystem. …”
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Antibiotics resistance in El Tor Vibrio cholerae 01 isolated during cholera outbreaks in Mozambique from 2012 to 2015. by Liliana Candida Dengo-Baloi, Cynthia Amino Semá-Baltazar, Lena Vania Manhique, Jucunu Elias Chitio, Dorteia Luísa Inguane, José Paulo Langa

“…Antibiotic therapy is recommended in specific situations for management and control of cholera outbreaks. However, an increase in resistance rates to antibiotics by Vibrio cholerae has been reported in several epidemic outbreaks worldwide. …”
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STRATEGIC COMPETENCE AS A GUARANTEE OF PROFESSIONAL ACTIVITY OF A MODERN IT SPECIALIST by Volkova Nataliia, Oliinyk Iryna, Karpova Maryna

“…The article examines the current problem of professional training of future IT specialists in the context of forming their strategic competence because it is critical for university graduates in the field of IT to be able to strategically plan actions in different ways for effective implementation in their professional activities. …”
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Role of Interleukins in Type 1 and Type 2 Diabetes by Roha Asif, Ammara Khalid, Tolga Mercantepe, Aleksandra Klisic, Sana Rafaqat, Saira Rafaqat, Filiz Mercantepe

“…While their diagnostic and therapeutic potential is increasingly recognized, future research must address current limitations through isoform-specific targeting, context-aware interventions, and validation in large-scale, human cohorts. …”
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Consequences, costs and cost-effectiveness of workforce configurations in English acute hospitals by Peter Griffiths, Christina Saville, Jane Ball, David Culliford, Jeremy Jones, Francesca Lambert, Paul Meredith, Bruna Rubbo, Lesley Turner, Chiara Dall’Ora

“…These findings lend support to policy initiatives aimed at increasing the supply of RNs. Study registration This study is registered as Current Controlled Trials ClinicalTrials.gov NCT04374812. …”
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Administrator Turnover: The Roles of District Support, Safety, Anxiety, and Violence from Students by Andrew H. Perry, Linda A. Reddy, Andrew Martinez, Susan D. McMahon, Eric M. Anderman, Ron A. Astor, Dorothy L. Espelage, Frank C. Worrell, Taylor Swenski, Kailyn Bare, Christopher M. Dudek, Jared Hunt, Adriana I. Martinez Calvit, Hyun Ji Lee, Xi Liu

“…Findings highlight the importance of district support of administrators for reducing mental health concerns and transfer/quit intentions in the context of student violence against school administrators. …”
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Long-term interleukin-6 levels and subsequent risk of coronary heart disease: two new prospective studies and a systematic review. by John Danesh, Stephen Kaptoge, Andrea G Mann, Nadeem Sarwar, Angela Wood, Sara B Angleman, Frances Wensley, Julian P T Higgins, Lucy Lennon, Gudny Eiriksdottir, Ann Rumley, Peter H Whincup, Gordon D O Lowe, Vilmundur Gudnason

“…An updated systematic review of electronic databases and other sources identified 15 relevant previous population-based prospective studies of IL-6 and clinical coronary outcomes (i.e., MI or coronary death). Including the two current studies, the 17 available prospective studies gave a combined odds ratio of 1.61 (95% CI 1.42-1.83) per 2 SD increase in baseline IL-6 (corresponding to an odds ratio of 3.34 [95% CI 2.45-4.56] per 2 SD increase in usual [long-term average] IL-6 levels).…”
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Cognitive Outcomes and Functional Performance for Patients After Open Heart Surgery by Mona A. Hassenien, Sahar Y Mohammad, Dalia A. Ameen

“… Context: Open heart surgery is a lifesaving procedure for patients who need coronary artery bypass graft (CABG) and heart valve replacement or repair (HVR). …”
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Compatibility of the CEN-ISO/TS 82304-2 Health App Assessment Framework With Catalan and Italian Health Authorities’ Needs: Qualitative Interview Study by Petra Hoogendoorn, Mariam Shokralla, Romy Willemsen, Nick Guldemond, María Villalobos-Quesada

“… BackgroundHealth authorities of European Union (EU) member states are increasingly working to integrate quality health apps into their health care systems. …”
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miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

“…Conversely, inhibiting miR-34a-5p resulted in an increase in cell growth and a decrease in programmed cell death. …”
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Direct and indirect crisis of food security due to COVID-19 emergence in Addis Ababa and Amhara regions, Ethiopia: a lesson for the inevitable pandemics by Daniel Teshome Gebeyehu, Leah East, Stuart Wark, Md Shahidul Islam

“…The objective of the current study was to assess both the direct and indirect impact of COVID-19 on individuals’ food security in the metropolitan and regional context of Ethiopia. …”
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The effect of social networks on the development of gastronomy – the way forward to the development of gastronomy tourism in Serbia by Dragan Vukolic, Tamara Gajić, Mirjana Penic

“…Purpose – To evaluate some of the current discussions about the possible impacts of social networks on the development of gastronomy in the Republic of Serbia. …”
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