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  1. 181
  2. 182

    Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4 by Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao

    Published 2025-12-01
    “…Furthermore, MUC4 overexpression in the context of HIF-1α knockout was positively correlated with increased ECM protein expression and TIF. …”
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  3. 183

    Multiomics-based analysis of the mechanism of ammonia reduction in Sphingomonas by Wang Mingcheng, Wang Mingcheng, Wang Mingcheng, Wang Mingcheng, Liu Daoqi, Xia Huili, Wang Gailing, Liu Chaoying, Guo Yanan, Guo Aizhen, Guo Aizhen, Guo Aizhen

    Published 2025-05-01
    “…These results suggested that under high ammonium sulfate level, the flux of purine and arginine metabolism pathways in Sphingomonas sp. Z392 might decrease, while the flux of nitrogen metabolism pathway might increase, resulting in increased nitrite content and NH3 release. …”
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  4. 184

    Legal Challenges of Marine Insurance Laws in the Use of Unmanned Ships by Mahsa Bahadoran- Baghbaderani, Masoud Shirani, Reza Soltani

    Published 2025-03-01
    “…Furthermore, these vessels promise lower operational costs, optimized ship designs, increased cargo capacity, reduced fuel consumption, and consequently, a substantial decrease in environmental pollutants. …”
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  5. 185

    Generative AI may create a socioeconomic tipping point through labour displacement by Jo-An Occhipinti, William Hynes, Ante Prodan, Harris Eyre, Roy Green, Sharan Burrow, Marcel Tanner, John Buchanan, Goran Ujdur, Frederic Destrebecq, Christine Song, Steven Carnevale, Ian B. Hickie, Mark Heffernan

    Published 2025-07-01
    “…Results indicate that even a moderate increase in the AI-capital-to-labour ratio could increase labour underutilisation to double its current level, decrease per capita disposable income by 26% (95% interval, 20.6–31.8%), and decrease the consumption index by 21% (95% interval, 13.6–28.3%) by mid-2050. …”
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  6. 186

    Impacts of CACNB4 overexpression on dendritic spine density in both sexes and relevance to schizophrenia by Emily M. Parker, Nathan L. Kindja, Rebecca A. DeGiosio, Ryan B. Salisbury, Josh M. Krivinko, Claire E. J. Cheetham, Matthew L. MacDonald, Weijia Fan, Bin Cheng, Robert A. Sweet

    Published 2024-12-01
    “…Dendritic spine density is significantly decreased in schizophrenia in the primary auditory cortex where it is driven by the loss of small spines, and small spine loss associated with increased peptide levels of ALFDFLK found in the VGCC β subunit β4. …”
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  7. 187

    Re-use of Building Products in the Netherlands by Loriane Icibaci

    Published 2019-01-01
    “…These characteristics indicated to influence (increase) housing survivability. Especially in the West, where most activities in the national housing stock are concentrated, the increase of private single-family houses influences overall housing survivability in the Netherlands (particularly when the pre-1946 group gradually decreases). …”
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  8. 188

    Two decades of cropland monitoring in Changsha-Zhuzhou-Xiangtan city group: trends and future predictions by Wenbo Zhang, Dazhao Fan, Song Ji, Yang Dong, Dongzi Li, Ming Li

    Published 2024-01-01
    “…The results demonstrated that the cropland area in the CZTCG in the past 20 years has shown a two-stage trend of increasing (2000–2015, increase of 8.25%) and decreasing (2015–2020, decrease of 2.91%), and the main reasons for cropland loss in the whole process of change were forest and building, with serious loss of cropland area in Changsha County and Wangcheng District. …”
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  9. 189

    miR-34a-5p modulation of polycystic ovary syndrome via targeting the NOTCH signaling pathway by Kexin Zhang, Xiaomeng Wang, Fang Liu, Hong Lin, Yan Wang, Min Zhao, Xiaofei Wang, Yijing Chu, Lin Xu

    Published 2025-03-01
    “…Conversely, inhibiting miR-34a-5p resulted in an increase in cell growth and a decrease in programmed cell death. …”
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  10. 190

    Granulocyte-Macrophage Colony-Stimulating Factor Inhibition Ameliorates Innate Immune Cell Activation, Inflammation, and Salt-Sensitive Hypertension by Hannah L. Smith, Bethany L. Goodlett, Gabriella C. Peterson, Emily N. Zamora, Ava R. Gostomski, Brett M. Mitchell

    Published 2025-07-01
    “…SSHTN is defined by an increase in blood pressure (BP) in response to high dietary salt, and is associated with heightened cardiovascular risk, renal damage, and immune system activation. …”
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  11. 191

    Comparison of Bone Mineral Density in Lumbar Spine and Fracture Rate among Eight Drugs in Treatments of Osteoporosis in Men: A Network Meta-Analysis. by Ling-Xiao Chen, Zhi-Rui Zhou, Yu-Lin Li, Guang-Zhi Ning, Tian-Song Zhang, Di Zhang, Shi-Qing Feng

    Published 2015-01-01
    “…Zoledronate ranked first for increasing the BMD in LS, and teriparatide (20mg) was ranked first for decreasing the fracture rate.…”
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  12. 192

    An Agent-Based Simulation and Optimization Approach for Sustainable Urban Logistics: A Case Study in Lisbon by Renan Paula Ramos Moreno, Rui Borges Lopes, Ana Luísa Ramos, José Vasconcelos Ferreira, Diogo Correia, Igor Eduardo Santos de Melo

    Published 2025-05-01
    “…This study examines the PDP-TW in an urban logistics context using an integrated approach that combines an agent-based simulation model and an optimization model. …”
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  13. 193
  14. 194

    DEVELOPMENT PROSPECTS OF THE RUSSIAN MARKET OF TECHNICAL SERVICING AND REPAIR IN THE СONTEXT OF A PANDEMIC by O. A. Tettsoeva

    Published 2021-02-01
    “…Currently, at a time of decreasing automotive production caused by the suspension of the plants in the period of lockdown, the reduction in purchasing power of communities connected with the risk of unemployment occurrence in consequence of business failures, the decline in wages and lower vacancy rates, is foreseen reduced demand for new cars against the background of significant increase in sales volumes in the used cars market segment and, therefore, sharp increase in demand for car services performing technical servicing and repair. …”
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  15. 195

    Analysis of Adaptation of Students Studying under the Flipped Classroom Model to the Conditions of Distance Learning by G. R. Chaynikova

    Published 2020-10-01
    “…Survey analysis showed that the transition to distance learning was a challenge for most students and demanded from them to make significant efforts  to adapt, which was manifested in a decreased level of satisfaction with the results of their learning activities in general, an increased level of anxiety, as well as highlighting a number of difficulties that they had to face. …”
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  16. 196

    Insulin Modulates NK Cell Activity in Liver Fibrosis MASH Patients via the STING Pathway by Johnny Amer, Ahmad Salhab, Amiram Ariel, Rifaat Safadi

    Published 2025-06-01
    “…While STING is well-established in various immune cells, its role in natural killer (NK) cells, particularly within the context of liver fibrosis, remains inadequately explored. …”
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  17. 197

    Shifting of Distribution and Changing of Antibiotic Resistance in Gram-Positive Bacteria from Bile of Patients with Acute Cholangitis by Hao Y, Li L, Du W, Lu J

    Published 2025-02-01
    “…Yuqi Hao,1 Lianxin Li,2 Wenting Du,1 Jinshuai Lu1 1Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China; 2Endoscopy Center, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of ChinaCorrespondence: Jinshuai Lu, Department of General Internal Medicine, People’s Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang, People’s Republic of China, Email lujinshuai@xjrmyy.comBackground: Gram-negative bacteria are the predominant pathogens responsible for biliary infections; however, the prevalence of Gram-positive bacteria is currently increasing. Investigating the bacterial spectrum and evolving antibiotic resistance patterns of Gram-positive bacteria is crucial for optimizing the management of acute cholangitis, particularly in the context of the global rise in antibiotic resistance.Methods: This retrospective analysis focused on Gram-positive bacteria isolated from the bile of patients undergoing biliary drainage with acute cholangitis at our hospital from January 1, 2018, to March 31, 2024. …”
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  18. 198

    Impact of Thermal Power Plant Waste Products on Corrosion Dynamics of Pipeline Carbon Steel Alloy in Soil Aqueous Solutions by Camila Porporatti Rosso, Eduardo Ceretta Moreira, Matheus Henrique Baesso, André Gündel, Alexandre Ferreira Galio

    Published 2025-05-01
    “…Adding desulfurization by-products to soil solutions (DBS) created a transpassive layer during potentiostatic polarization, with a passive current density of about 10μA.cm-2. EIS measurements showed a substantial increase in polarization resistance, with the DBS exhibiting nearly 700 times higher resistance than the standard soil solution (SSS) at 0V (OCP). …”
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  19. 199

    Bleomycin: A worthy alternative by Gursev Sandlas, Paras Kothari, Parag Karkera, Abhaya Gupta

    Published 2011-01-01
    “…Complications of the therapy were few and far between. 2 patients developed fever after injection, one patients reported a transient increase in size of swelling, 2 patients have developed discoloration of the overlying skin and are currently being followed up for final outcome. …”
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