Polymer carrier selection for creation of diosmin solid dispersion system by hot melt extrusion by A. A. Danilova, E. V. Vishnyakov, E. S. Surbeeva, K. A. Gusev, D. N. Maimistov, E. V. Flisyuk

“…Particular importance in the context of current approach is attached to the selection of an effective polymer matrix.Aim. …”
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Management system and optimal control for three-dimensional visualization and maintenance of thermal power plant by Zhiqiang Feng, Qiuxiang Liang, Mingyi Wei, Lei Li, Youzhu Bu, Yanqing Xin

“…After optimization by CNN technology, the response time of the system is increased by 5%. The calculation cost is reduced by 15%, and the data throughput is increased by 13%. …”
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Potential of the mortgage housing lending market by N. I. Parusimova, D. A. Dobrin

“…However, under conditions of increased uncertainty-driven by both external and internal factors, as well as technological and social changes – the Russian mortgage housing lending market is undergoing continuous transformation and facing new contemporary challenges. …”
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Pharmacokinetics of levosimendan in critically Ill children on extracorporeal membrane oxygenation: a prospective observational study by Stéphane Bertin, David Haefliger, Maria-Helena Perez, Monia Guidi, Monia Guidi, Laurent A. Decosterd, Vivianne Chanez, Ermindo R. Di Paolo, Thierry Buclin, Françoise Livio

“…This suggests that dosage should be increased in this context, to achieve optimal exposure of levosimendan and its active metabolite.…”
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Psychological Service in the Education System as a Phenomenon by Irina V. Dubrovina

“…The article highlights a relevant problem of upbringing students within modern school education as considered in the context of the role of interaction between psychology and pedagogy. …”
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Optimization of Distillation Conditions for Improved Recovery of Phthalides from Celery (Apium graveolens L.) Seeds by Adam Kokotkiewicz, Anna Badura, Żaneta Tabaczyńska, Andżelika Lorenc, Adam Buciński, Maria Luczkiewicz

“…The change of distillation mode from HD to SDE significantly increased the oil yield of whole seeds (from 2.8 to 5.8% for 6 h processing) while maintaining its high phthalide content (62.5%), which translated to an increase in the total phthalide yield from 19.4 to 36.0 g/kg.…”
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GBD: incidence rates and prevalence of anxiety disorders, depression and schizophrenia in countries with different SDI levels, 1990–2021 by Jueqi Wang, Xue Guan, Ning Tao

“…Data were categorized into 5-year age groups and 95% uncertainty intervals (UI) were calculated to account for data variability.ResultsIn countries with different SDI levels, the age-standardized average annual percentage change (AAPC) in the incidence of anxiety were all shown to be increasing, and there were large gender differences between the different SDI levels, with a maximum of 0.97 (0.76–1.18) for females in countries with a high SDI level, Age-standardized more rates per 100,000 people in high SDI countries, from 658.87 in 1990 to 841.56 in 2021, and the largest gender differences in countries with a low to moderate SDI level, with AAPCs for males and females of 0.04 (0.04–0.05), 0.86 (0.63–1.09); for depression, only the countries with medium-high SDI levels were statistically significant compared to the countries with medium-low SDI levels, with AAPCs of 0.05 (0.04–0.07), 0.04 (0.04–0.05); for schizophrenia in addition to the AAPCs of the countries with medium-high SDI levels showed an increase of 0.16 (0.13–0.18); the rest decreased.ConclusionThis study highlights the current status of global incidence and prevalence of mental disorders and examines the complex interactions between the period of onset and cohort of onset of mental disorders using APC modeling, with differences in gender differences in mental disorders in countries with different SDIs, and significant differences in countries with low to medium SDI levels, requiring further exploration of the mechanisms by which socio-economic development influences gender-specific mental health. …”
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Evolution of standardization of therapeutic and diagnostic allergens produced in Russia by S. S. Masalskiy, E. I. Sakanyan, M. A. Yasnaya

“…A method of competitive enzyme-linked immunosorbent assay using specific sera containing specific IgE antibodies is used for this purpose.In addition, the specific activity of allergen preparations is certified through three additional characteristics: total protein content (using the Bradford method), protein profile (through electrophoresis in a polyacrylamide gel with sodium dodecyl sulfate under reducing conditions), and authenticity through the presence of major specific components, which is determined by the Western blot method using sera containing IgE antibodies specific for the corresponding allergen.Currently, in the Russian Federation, the standardization of therapeutic and diagnostic allergens is conducted simultaneously according to two indicators: protein nitrogen content, expressed in Protein Nitrogen Units (PNU), and allergenic (specific) activity expressed in units of allergenic activity per milliliter (EAA/ml). …”
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Molecular Layering Synthesis and Investigation of Nanostructured Oxide Layers in High Aspect Ratio Substrates by A. P. Baraban, V. A. Dmitriev, A. V. Drozd, V. A. Moshnikov

“…Comparative tests of MCP samples containing the synthesized films were carried out.Conclusion. …”
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The impact of post-defoliation foliage of Pinus halepensis Mill. on the larval performance of Thaumetopoea pityocampa and its relationship with the tree-induced defense by Guadguad M, Sbabdji M, Mouissa H, Chebrouk F

“…Induced defense in trees refers to the increased production of specific substances in response to herbivore attacks, which negatively affects the herbivore. …”
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Pulsed electrodeposition and characterization of HAp-Ta2O5 composite coating on NiTi for orthopedic applications by Sima Mohammadi Kahnamouei, Mir Saman Safavi, Jafar Khalil-Allaf

“…In this study, hydroxyapatite-tantalum pentoxide (HAp-Ta2O5) composite coatings were electrodeposited on the NiTi from the aqueous bath containing calcium nitrate tetrahydrate and ammonium dihydrogen phosphate salts along with different concentrations of Ta2O5 nanoparticles, i.e., 0–1 g/L, under pulsed current at a density of 15 mA/cm2. …”
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THE TREATMENT HYPERSENSITIVITY OF DENTAL HARD TISSUES IN PERIODONTAL TISSUES DISEASES by E.S. Genzytskaya

“… Treatment of dental hypersensitivity in periodontal disease, the prevalence of which is almost 94%, is the urgent problem of dentistry. Current treatments of hyperesthesia of hard dental tissues based on the ability of enamel and dentin remineralization. …”
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Model of regional human resource management as a tool for sustainable development of the socioeconomic system by Veronika S. Zhukova

“…Integration of regional human resource management into the process of achieving goals of national economy is of particular importance in the context of the need for a comprehensive and systemic approach to the development of territories. …”
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Evaluation of biokinetics and dosimetry in [131I]-NaI therapies: whole-body images quantification versus lower limb region by Bianca Lemos Lima, Jamille da Silveira Almeida, Maria da Penha Albuquerque Potiens, Rogério Alexandre Pelissoni, Marcelo Tatit Sapienza, Carlos Alberto Buchpiguel, José Willegaignon

“…As the current dosimetric protocol can be performed by delimiting a region of interest (ROI) in whole body images to evaluate the biokinetics and absorbed dose by the patient, the objective of this study was to analyze the possibility that this measurement was restricted to only one thigh region. …”
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Teaching in the Digital Age—Developing a Support Program for Nursing Education Providers: Design-Based Research by Stefan Walzer, Carolin Barthel, Ronja Pazouki, Helga Marx, Sven Ziegler, Peter Koenig, Christiane Kugler, Stefan Jobst

“…The findings of this research can be used as a basis for the development of similar programs in other educational and health care contexts.…”
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Design and implementation of a project management training program to develop workforce ready skills and career readiness in STEM PhD students and postdoctoral trainees by Elizabeth J. Salm, Caleb C. McKinney

“…Posttest data (n = 25) reveal a significant increase (p < 0.0001) in project management self-efficacy measures across the aforementioned pain point scales. …”
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Exploring Long-Term Clean Energy Transition Pathways in Ghana Using an Open-Source Optimization Approach by Romain Akpahou, Jesse Essuman Johnson, Erica Aboagye, Fernando Plazas-Niño, Mark Howells, Jairo Quirós-Tortós

“…An open-source energy modelling tool was used to assess four scenarios accounting for current policies and additional alternatives to pursue energy transition goals. …”
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Operationalising energy sufficiency for low-carbon built environments in urbanising India by Ashok B. Lall, Girisha Sethi

“…Current trends towards high-rise and high-density residential development contribute significantly to the demand for embodied and operational energy. …”
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Assessing the Efficacy of Seawater Batteries Using NASICON Solid Electrolyte by Mihaela Iordache, Anișoara Oubraham, Mihaela Bazga, Gheorghe Eugen Ungureanu, Simona Elena Borta, Adriana Marinoiu

“…The need to reduce greenhouse gas emissions and guarantee a stable and reliable energy supply has resulted in an increase in the demand for sustainable energy storage solutions over the last decade. …”
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A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer by Gary Middleton, Helen L. Robbins, Peter Fletcher, Joshua Savage, Manita Mehmi, Yvonne Summers, Alastair Greystoke, Nicola Steele, Sanjay Popat, Pooja Jain, James Spicer, Judith Cave, Paul Shaw, David Gilligan, Danielle Power, Dean Fennell, Maya Bajracharya, David J. McBride, Uma Maheswari, Alexander M. Frankell, Charles Swanton, Andrew D. Beggs, Lucinda Billingham

“…Abstract There are no current stratified medicine options for STK11-deficient NSCLC. …”
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