Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification by Jun Chen, Wenyi Ye

“…Context Hyperpigmentation, a common skin condition marked by excessive melanin production, currently has limited effective treatment options.Objective This study explores the effects of Tao-Hong-Si-Wu decoction (THSWD) on hyperpigmentation and to elucidate the underlying mechanisms.Materials and methods We employed network pharmacology, Mendelian randomization, and molecular docking to identify THSWD’s hub targets and mechanisms against hyperpigmentation. …”
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Residents’ Perceptions of Impending Forced Relocation in Urban China by Xin Li

“…On the other hand, many homeowners and older people are unwilling to move, since their current neighbourhood makes them feel rooted and enables them to develop living strategies to relieve their deprived socio-economic situation. …”
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Identification of Writing Patterns, Motivations, and Barriers to Publishing Articles by Faculty Members in the Humanities Departments of the University of Tabriz in Perestigious In... by Hashem Atapour, Solmaz Zardary, Fereshteh Javadi

“…Accordingly, the publication of scientific outputs resulting from faculty research is currently a fundamental requirement and, in some cases, mandatory at universities. …”
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Enhancing referrals to Child and Adolescent Mental Health Services: the EN-CAMHS mixed-methods study by Kathryn M Abel, Pauline Whelan, Lesley-Anne Carter, Heidi Tranter, Charlotte Stockton-Powdrell, Kerry Gutridge, Lamiece Hassan, Rachel Elvins, Julian Edbrooke-Childs

“…Conclusions The findings from the quantitative and qualitative analyses, patient and public involvement and senior stakeholder consultations during dissemination activities identified the following as important aspects of solutions to the current problems within the referral process: Must haves: Increased understanding about what CAMHS can/cannot provide. …”
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The role of Pakistan Medical & Dental Council in steering undergraduate medical curriculum reforms in Pakistan by Gohar Wajid, Lubna Baig, Syeda Kauser Ali, Usman Mahboob, Ahsan Sethi, Rehan Ahmed Khan

“…There has been an exponential increase in the number of medical colleges in Pakistan over the past few decades, especially in the private sector. …”
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CRITICAL ANALYSIS OF LOADING BY TECHNOLOGY RECONDITIONING, WITH APPLICATION TO REPAIR PIECES OF AUTO INDUSTRY by Gheorghe AMZA

“…One problem is that the presence of detonation ultra-dispersed diamonds in the grain metal coating of diamond powders not only improves the coating functional reliability in protection from destruction in the subsequent pressing and sintering in the production tool, but also resistance of such coating to the opening of the diamond cutting basis of the grains on the grinding wheel working surface that come into working contact with the material being processed. An analysis of the features of an effective exploitative destruction of detonation ultra-dispersed diamonds in the metal coating using electric current in the tool of the diamondspark grinding processes is presented.…”
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Design and meshing characteristics of curvilinear cylindrical gears with asymmetric teeth by Xuegang Zhang

“…Larger contact patterns increase edge contact pressure and transmission error amplitude. …”
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Research on Meshing Stiffness and Bearing Performance of Logarithmic Modified Composite Roller Movable Tooth by Yali Yi, Lei He, Liang Xie, Shuang Zhang, Herong Jin, Zhengxiang Zhou, Yazheng Zhou

“…Aiming at the development requirements of large load capacity and long life of wheel-side deceleration system， a logarithmic modified composite roller movable tooth transmission is proposed. Combined with the current research on the contact deformation of hollow roller， a method for calculating the meshing deformation of logarithmic modified composite roller is proposed by introducing design parameters <italic>Δ_c</italic> and <italic>Δ_e.…”
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A quantitative assessment of the behavior of metallic elements in urban soils exposed to industrial dusts near Dunkerque (northern France) by M. Casetta, S. Philippe, L. Courcot, D. Dumoulin, G. Billon, F. Baudin, F. Henry, M. Hermoso, J. Caillaud

“…In this context, the monitoring of industrial PTEs in these urban soils is highly recommended, considering (1) the presence of allotment gardens in the vicinity of emitters and (2) the potential evolution of soil conditions due to increasing flood events.…”
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Brain Structural Correlates of EEG Network Hyperexcitability, Symptom Severity, Attention, and Memory in Borderline Personality Disorder by Andrea Schlump, Bernd Feige, Swantje Matthies, Katharina von Zedtwitz, Isabelle Matteit, Thomas Lange, Kathrin Nickel, Katharina Domschke, Marco Reisert, Alexander Rau, Markus Heinrichs, Dominique Endres, Ludger Tebartz van Elst, Simon Maier

“…<b>Introduction</b>: Previous neuroimaging studies have reported structural brain alterations and local network hyperexcitability in terms of increased slow-wave electroencephalography (EEG) activity in patients with borderline personality disorder (BPD). …”
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Risk Screening, Early Detection, and Management of Acute Popliteal Artery Thrombosis Following Total Knee Arthroplasty: Three Case Reports by Vikas Kulshrestha, Pardeep Kumar, Anjan Prabhakara, Munish Sood, Soma Kulshrestha, Manu Mohan

“…Acute limb ischemia (ALI) is an infrequent but potentially devastating complication that can occur after total knee arthroplasty (TKA). Currently, there is a lack of structured protocols for screening, prevention, early detection, and management of ALI in the context of TKA. …”
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Early Warning and Assessment of Chinese Marathon Events' Exposure to High Temperature under Climate Warming by Yu Dandan, Shi Yong, Chen Shuman, Mei Yuru

“…In recent years, the number of marathons in China has expanded rapidly, but the impact of high-temperature weather has become more apparent. Current high-temperature early warning systems lack tailored thresholds and unified standards for sports scenarios. …”
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Energetische upgrading van Nederlandse Wederopbouw flats by Frits Schultheiss

“…The theoretical relevance is to increase scientific knowledge in the field of energetic and circular upgrading. …”
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Nuclear pore dysfunction and disease: a complex opportunity by Charlotte M. Fare, Jeffrey D. Rothstein

“…In this review, we summarize the current understanding of nuclear pore biology in physiological and pathological contexts and discuss potential therapeutic approaches for addressing nuclear pore injury and dysfunctional nucleocytoplasmic transport.…”
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SOUTH AFRICAN USERS’ FUNCTION AND EXPERIENCE WITH A MAGNETORHEOLOGICAL MICROPROCESSOR KNEE: A MIXED METHODS STUDY by Surona Visagie, Benje Theron

“…CONCLUSION: This study provides context specific scientific evidence that may support funding decisions for MPKs in South Africa. …”
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Development and biomechanical evaluation of a 3D printed analogue of the human lumbar spine by Siril Teja Dukkipati, Mark Driscoll

“…Moreover, there are increasing ethical concerns with human dissection practices. …”
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Building a Robust Scenario Library for Safety Assurance of Automated Driving Systems: A Review by Antonio A. Bruto da Costa, Patrick Irvine, Tudor Dodoiu, Siddartha Khastgir, Paul Jennings

“…While every region has its specificities, certain contexts pose particular difficulties in scenario development. …”
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Recent research progress on metal ions and metal-based nanomaterials in tumor therapy by Yongcheng Xu, Aikebaier Reheman, Wenhua Feng, Wenhua Feng, Wenhua Feng

“…In addition, tumor recurrence and metastasis are also difficult problems faced in clinical treatment. In this context, the importance of metal-based nanomaterials in tumor therapy is increasingly highlighted. …”
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The Ecological Restoration Strategies in Terrestrial Ecosystems Were Reviewed: A New Trend Based on Soil Microbiomics by Yuanqi Zhao, Xiaojuan Yuan, Weiwei Ran, Zhibing Zhao, Di Su, Yuehua Song

“…This review aims to address the ecological crises currently experienced by diverse terrestrial ecosystems and to provide a comprehensive overview of the specific practices of soil microorganisms in the context of ecological restoration. …”
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Simulation Study on the Open-Circuit Voltage of Amorphous Silicon p-i-n Solar Cells Using AMPS-1D by B.M. Omer, F.A. Mohammed, A. Seed Ahmed Mahgoub

“…The simulated result of illuminated current density-voltage characteristics was in a good agreement with experimental values. …”
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