Hypoxia-inducible factor-1α promotes tubulointerstitial fibrosis via the upregulation of Muc4 by Zhong-Tang Li, Xin-Hui Hu, Wei-Jie Ni, Zuo-Lin Li, Bi-Kun Huang, Yu Zhang, A-Feng Miao, Jing-Yuan Cao

“…Furthermore, MUC4 overexpression in the context of HIF-1α knockout was positively correlated with increased ECM protein expression and TIF. …”
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Drivers of Food Service Need and Use among Non-Hispanic Black and Hispanic Men with Chronic Conditions in the United States by Jeong-Hui Park, Tyler Prochnow, Ledric Sherman, Caroline D. Bergeron, Ashley Merianos, Babatunde Olubajo, Sanjeela Gandhari, Matthew L. Smith

“…Food insecurity is predominant and differs across certain races and ethnicities, which highlights the importance of community-based food service access and utilization. In this context, the current study examined factors associated with community-based food service needs and utilization among middle-aged and older non-Hispanic Black and Hispanic men with chronic conditions. …”
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Thrombospondin-I is a critical modulator in non-alcoholic steatohepatitis (NASH). by Jessica Min-DeBartolo, Franklin Schlerman, Sandeep Akare, Ju Wang, James McMahon, Yutian Zhan, Jameel Syed, Wen He, Baohong Zhang, Robert V Martinez

“…Activation of PPARα pathway was supported by observed decrease in serum lipid levels. Our findings provide important insights into the role of TSP-1 in context of NAFLD/NASH and TSP-1 may be a target of interest to develop anti-fibrotic therapeutics for NAFLD/NASH.…”
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Modern ideas about the role of the galaninergic system in the pathogenesis of heart failure and myocardial remodeling by A. A. Yafarova, A. R. Kiselev, A. F. Sheptulina, O. M. Drapkina

“…Various experimental models of heart damage showed that under stress conditions and the action of galanin and its derivatives, carbohydrate metabolism in cardiomyocytes improved, oxidative stress decreased due to antioxidant effect, and hyperproduction of reactive oxygen species by mitochondria decreased. …”
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‘It was a joint plan we worked out together’. How the I-WOTCH programme enabled people with chronic non-malignant pain to taper their opioids: a process evaluation by Martin Underwood, Kate Seers, Charles Abraham, Harbinder Kaur Sandhu, Vivien P Nichols, Sam Eldabe, Alleyne Sharisse, Balasubramanian Shyam, Betteley Lauren, Booth Katie, Carnes Dawn, D Furlan Andrea, Haywood Kirstie, Iglesias Urrutia C Paola, Lall Ranjit, Manca Andrea, Mistry Dipesh, Noyes Jennifer, Rahman Anisur, Shaw Jane, KY Tang Nicole, Taylor Stephanie, Tysall Colin, Underwood Martin, J Withers Emma

“…Background The Improving the Wellbeing of people with Opioid Treated CHronic pain (I-WOTCH) randomised controlled trial found that a group-based educational intervention to support people using strong opioids for chronic non-malignant pain helped a significant proportion of people to stop or decrease opioid use with no increase in pain-related disability. …”
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Economic Analysis of Global CO₂ Emissions and Energy Consumption Based on the World Kaya Identity by Alina Yakymchuk, Simone Maxand, Anna Lewandowska

“…Thus, an unexpected increase in the population likely does not have short-term effects on CO₂ emissions, and the responses to GDPpc and energy intensity both decrease after some periods, while the shock in carbon intensity shows a significant effect even after 10 years. …”
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Land use dynamics in Sagara River Catchment in Dodoma Region, Tanzania by Dominico Benedicto Kilemo

“… Abstract Context and background: The Sagara hills provide key ecosystem services to the communities in Kongwa and Mpwapwa districts in Dodoma region. …”
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Complementary Strategy of Maternal Immunization with RSVpreF Vaccine and Monoclonal Antibodies for the Prevention of Respiratory Syncytial Virus Among Italian Infants: A Cost-Effec... by Barbara Polistena, Fabio Midulla, Giovanni Sotgiu, Daniela d’Angela, Roberto Di Virgilio, Federico Spandonaro

“…The strategy results cost-saving: the complementary strategy saves € 6.0 mil and € 8.4 mil per year in the NHS and in the Societal perspective, respectively; the complementary strategies of maternal vaccination plus nirsevimab also prove to have significant benefits versus the monoclonal antibody alone, providing a decrease equal to 941 annual hospitalizations (−9.0%), 6 years of life recovered, and an increase of 20 QALYs. …”
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Structural and Spatial-Functional Changes in the Development of Enterprises in Ukraine by Ivan Burtnyak, Oleksandr Kusnir, Roman Kashevskyi

“…The results of the study indicate a decrease in the spatial dynamics of private enterprises, inertia, spatial polarization and mosaicism. …”
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Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing by Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

“…CE-MS peptidome analysis identified 191 significantly altered peptides in severely injured patients. A consistent increase in the abundance of peptides from A1AT, AHSG, and HBA1 was observed, while peptides derived from PIGR and UROM were consistently decreased. …”
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Banking Models Under the Impact of the Post-Crisis Organizational Changes Apt to Confer Sustainable Financial Stability - Romanian Experience by Claudia Gabriela Baicu, Olimpia State

“…The banking model practiced in Romania continues to be the traditional one. Currently, the most important challenges of the Romanian banking system are the growth of the non-performing loans, the loans in foreign currency to unhedged borrowers, the pressure to meet the Basel III requirements, as well as the possibility that the exposure of foreign banks towards Romania to decrease.…”
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FORMATION OF SUSTAINABLE COMPETITIVE ADVANTAGES OF THE EAEU MEMBER STATES IN THE INVESTMENT SPHERE by V. L. Abramov, P. V. Alekseev

“…The analysis shows a decrease in the indicators of economic growth, level of gross accumulation and attracted current and accumulated FDI in the national economies of the overwhelming majority of the EAEU countries, which makes it urgent and necessary to find new methodological and practical approaches to enhancement of the efficiency of integration processes. …”
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Comparative legal analysis of the labor law status of a higher school lecturer by T. F. Vysheslavova, S. A. Lukinova

“…The authors analyze the provisions of the current Russian labor legislation on the work of higher education lecturers in the context of globalization and the intensification of the global financial and economic crisis. …”
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Importance of Cheese Whey Processing: Supplements for Sports Activities – a Review by Patricia Fassina, Gabriela Quadros Nunes, Fernanda Scherer Adami, Márcia Inês Goettert, Claucia Fernanda Volken de Souza

“…Whey protein (WP) is a highly nutritious, commercially available alternative food source that is used primarily as a food supplement by athletes and physically active individuals to provide them with essential amino acids and bioactive peptides, and additional benefits have been attributed to WP consumption. In this context, the objective of this review was to explore current evidence regarding the consumption of different WP supplements in sports nutrition to elucidate their efficiency in affecting muscle hypertrophy, physical performance, response to muscle injury, weight loss, and body composition changes. …”
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Horticultural performance and QTL mapping of snap bean (Phaseolus vulgaris L.) populations with organic and conventional breeding histories by Hayley E. P. Richardson, Ryan M. King, Joel Davis, James R. Myers

“…IntroductionImproving crop cultivars for use on organic farms is pertinent, as current elite germplasm is less resilient within the more variable context of organic farm environments. …”
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La capacidad del Congreso de los Diputados español para impulsar la incorporación del enfoque de Coherencia de Políticas para el Desarrollo (CPD) by Pérez-González, J., Segovia-Moreno, M.

“…With the information provided by Proyecto Avizor, this article has aimed to find if, in the current Spanish political context, the political initiatives that will be needed to fulfill the 2030 Agenda’s goals, face extra obstacles and burdens during their approval procedures compared withthe rest of initiatives. …”
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Assessment of the Applicability and Steps of Implementing the Six Sigma Method in the Quality Management System of Additive Manufacturing by Ivan S. Kushnir, Anna P. Adylina, Tatyana A. Levina

“…With the help of a technological approach based on the DFSS cycle, through the application of each step sequentially, an effective change in the positive side of quality as the production process itself is possible: the manufacturing accuracy increases at each stage, the process is modernized with each new cycle, based on previous results; as well as finished products: the number of defects decreases, the mechanical characteristics of products improve.…”
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Cognitive and non-cognitive factors predict pigs’ positions in an aggression social network by Lucy Oldham, Saif Agha, Gareth Arnott, Mark Brims, Irene Camerlink, Agnieszka Futro, Victoria E. Lee, Andrea Doeschl-Wilson, Simon P. Turner

“…Betweenness centrality (a network position linking otherwise unconnected individuals) increased with network size and decreased with body weight. …”
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Errors in the diagnosis of types of diabetes mellitus: causes and prevention strategies (literature review and own research results) by K.I. Gerush, N.V. Pashkovska, O.Z. Ukrainets

“…This is due to the increasing heterogeneity of DM, blurring of the boundaries between its types, atypical disease course, the decreased diagnostic value of the essential criteria for DM types (age, presence of metabolic syndrome signs, ketosis, dependency on insulin therapy), presence of comorbid conditions, and limited availability of diagnostic tests to specify the type of diabetes. …”
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Overcoming immunosuppression in cancer: how ketogenic diets boost immune checkpoint blockade by Victoria E. Stefan, Daniela D. Weber, Roland Lang, Barbara Kofler

“…., high-fat low-carbohydrate diets, have been shown to have antiproliferative and immunomodulatory effects in various preclinical cancer studies. Here, we review current knowledge of the complex interplay of KDs and the anti-tumor immune response in the context of ICB therapy, to update our understanding of diet-induced immunometabolic reprogramming in cancer. …”
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