Young TPI: empowering animal-free science among the next- generation of scientists by Marta G. Valverde, Marta G. Valverde, Fatima Zohra Abarkan, Fatima Zohra Abarkan, Rebecca Van Eijden, Rebecca Van Eijden, Julia M. L. Menon, Julia M. L. Menon, Nikolas Gaio, Nikolas Gaio, Aarti Ramchandran, Aarti Ramchandran, Victoria C. De Leeuw, Victoria C. De Leeuw

“…In this context, Young TPI emerged as the-first-of-its-kind network comprising young professionals and students dedicated to revolutionizing scientific practices by catalyzing the shift towards animal-free research. …”
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Improvement of oilseed Brassica crops by Trichoderma use: Gene transfer and direct interaction by Tamara Sánchez-Gómez, Jorge Martín-García, Óscar Santamaría, Jorge Poveda

“…Global agriculture must urgently adopt a new approach to ensure adequate food production for the increasing population in the current context of adverse conditions, while prioritizing environmental sustainability. …”
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Improving mesophilic anaerobic digestion of compostable packaging through efficient and versatile thermo-alkaline pre-treatment by Gaël Huet, Julie Lamarque, Florian Monlau, Valentin Puchelle, Cecilia Sambusiti, Juliana Catalina Suarez Murcia, Sandra Domenek, Florian Pion, Emmanuelle Gastaldi

“…In the current European regulatory context, which requires its Member States to collect biowaste separately with a view to its organic recovery, the co-processing of compostable food packaging with biowaste by mesophilic anaerobic digestion (AD) offers the dual opportunity of promoting its conversion into biogas while reducing plastic contamination of the environment. …”
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Matching action to need: an analysis of Global Burden of Disease 2017 and population health data to focus adolescent health policy and actions in Myanmar by Karly I. Cini, Phone Myint Win, Zay Yar Swe, Kyu Kyu Than, Thin Mar Win, Ye Win Aung, Aye Aye Myint, Nisaa R. Wulan, Lia J. Burns, Elissa C. Kennedy, Kate L. Francis, Sanda, Su Mon Myat, Sithu Swe, Aung Ko Ko, Yadanar, Margaret Hellard, Chad L. Hughes, George C. Patton, Ali H. Mokdad, Peter S. Azzopardi

“…Overall, the dominant health problems were injuries for males and non-communicable disease for females in a context of ongoing burden of communicable and nutritional diseases for both sexes, and reproductive health needs for females. …”
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Pregnancy-related acute kidney injury leads to hypertension, reduced kidney function and cognitive impairment in postpartum rats by Ashley Griffin, Jamie Szczepanski, Shauna-Kay Spencer, Shauna-Kay Spencer, Lucia Solis, Teylor Bowles, Reanna Robinson, Jan M. Williams, Patrick B. Kyle, Kedra Wallace, Kedra Wallace

“…Both hypertensive disorders of pregnancy and Acute Kidney Injury (AKI) outside the context of pregnancy have been associated with an increased risk of developing Chronic Kidney Disease (CKD) and cognitive impairment. …”
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Genome-Wide DNA Methylation Analysis during Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells by Yangyang Cao, Haoqing Yang, Luyuan Jin, Juan Du, Zhipeng Fan

“…We found that the majority of cytosines in a CpG context were methylated in induced BMSCs. Our results also revealed that, along with the induced osteogenic differentiation in BMSCs, the average genomic methylation levels and CpG methylation in transcriptional factor regions (TFs) were increased, the CpG methylation level of various genomic elements was mainly in the medium-high methylation section, and CpG methylation levels in the repeat element had highly methylated levels. …”
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Apple phenotyping using deep learning and 3D depth analysis: An experimental study on fruitlet sizing during early development by Giorgio Checola, Damiano Moser, Paolo Sonego, Cristian Iob, Franco Micheli, Pietro Franceschi

“…Current research in apple-growing focuses on collecting extensive biometric data to better understand physiological processes, improve orchard productivity and predict yields. …”
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Évaluer les gains langagiers dans le cadre d’un apprentissage informel à l’étranger by Eva Donohoe

“…The VEPT showed an overall decrease of 7.59% in oral production, in contrast to the CAF analysis, which revealed significant gains in fluency and accuracy for students who went abroad. …”
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P22 | EXPLORING THE UNEXPECTED DUAL ROLE OF GARLIC DERIVATIVES IN REGULATING INVASIVENESS IN BREAST CANCER SUBTYPES

“…However, studies fail to account for the high heterogeneity within triple-negative breast cancer (TNBC), and no data are currently available about its effects on HER2+ tumors, which, despite recent therapeutic advances, frequently develop resistance. …”
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Trends in Research on Hypertrophic Cardiomyopathy and Mitochondria From 2003 to 2023: A Bibliometric Analysis by Lulu Yang, Heng Zhang, Zhiyang Zhu, Jianming Wang, Xiaojuan Liu, Lijie Lu, Jinliang Huang, Miaoran Wang, Zhengchuan Zhu

“…The investigation of mitochondria, particularly in the context of cardiovascular medicine and HCM, demonstrates an unstoppable momentum. …”
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Absence of progression risk of chronic kidney disease in patients with urine protein-creatinine ratio below 500 mg/g: a cohort study with competing risk analysis by Jiang Bai, Lijuan Zhang, Jingkai Di, Wenyu Wang, Yawen Wu, Yun Zhou, Yun Zhou, Yun Zhou

“…The results of the Fine and Gray competing risk survival regression model showed the same trend.ConclusionIn patients with CKD and UPCR levels below 500 mg/g, there was no increased risk of CKD progression associated with the higher proteinuria levels.…”
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PROTOCOL: The Application of Information and Communication Technologies in Physical Activity Interventions for Breast Cancer: A Scoping Review Protocol by Xin Chen, Maaz Imam, Yutong Yi, JJ Pionke, Lixcy Vega, Anna Arthur, Jessie Chin, Chungyi Chiu

“…The focus of the scoping review is guided by the mnemonic PCC (Population, Concept, Context) recommended by the JBI Manual for Evidence Synthesis. …”
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Clinical applications and research progress of remifentanil by Xu Liu, Zhipeng Meng, Fei Tong

“…This review synthesizes current evidence on its clinical applications, pharmacological advantages, and emerging challenges, including Opioid-Induced Hyperalgesia (OIH) and labor analgesia.MethodsThis study is a systematic evidence review. …”
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In Search of Law in Women’s and Gender Studies: Toward Critical Womanist Legal Studies by Mark Kessler

“…It also assesses the extent to which legal studies are evidenced in current published works in WGS journals and emphasizes how an increased emphasis on such scholarship permits researchers to usefully explore significant concerns in the field, including the operation of power and privilege, possible interventions in dominant cultural discourses, and legal constructions of intersecting roles of race, gender, class, and sexuality. …”
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Feasibility of cognitive testing and ecological momentary assessments using smartphones in middle aged and older adults with insomnia by Sara Ghadimi, Jason Ereso, Alexander J. Kaula, Nick Taptiklis, Francesca Cormack, Cathy Alessi, Jennifer L. Martin, Joseph M. Dzierzewski, Arash Naeim, Sarah Kremen, Tue Te, Constance H. Fung

“…We assessed the feasibility of self-administered cognitive testing via smartphone apps for collecting in-moment, in-context data about a person’s current state (ecological momentary assessment, EMA). …”
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Validation of the Mild Behavioral Impairment Scale (MBI-S) for brief self-assessment of Mild Behavioral Impairment in people without dementia by Paula Hinkl, Elmar Graessel, Nicolas Rohleder, Peter Landendoerfer, Thomas Kuehlein, Natascha Lauer, Anna Pendergrass

“…Abstract Background Mild Cognitive Impairment (MCI) and Mild Behavioral Impairment (MBI) are important constructs in the context of cognitive decline. MBI can be assessed with the Mild Behavioral Impairment Checklist (MBI-C). …”
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Reducing Plasmodium falciparum malaria transmission in Africa: a model-based evaluation of intervention strategies. by Jamie T Griffin, T Deirdre Hollingsworth, Lucy C Okell, Thomas S Churcher, Michael White, Wes Hinsley, Teun Bousema, Chris J Drakeley, Neil M Ferguson, María-Gloria Basáñez, Azra C Ghani

“…However, it remains unclear what overall reduction in transmission is achievable using currently available tools.<h4>Methods and findings</h4>We developed an individual-based simulation model for Plasmodium falciparum transmission in an African context incorporating the three major vector species (Anopheles gambiae s.s., An. arabiensis, and An. funestus) with parameters obtained by fitting to parasite prevalence data from 34 transmission settings across Africa. …”
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CO2 methanation over low-loaded Ni-M, Ru-M (M = Co, Mn) catalysts supported on CeO2 and SiC by Chopendra G. Wasnik, Maki Nakamura, Taiki Shimada, Hiroshi Machida, Koyo Norinaga

“…An efficient circulation and utilization of CO2 is critical in the current environmental context. Methanation, an exothermic process, emerges as a critical strategy for effective CO2 utilization. …”
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MECHANISMS FOR ENSURING THE ECONOMIC DEVELOPMENT OF RURAL AREAS THROUGH THE FORMATION OF THEIR ENERGY DEPENDENCE BASED ON THE INTENSIFICATION OF BIOFUEL PRODUCTION by Yuliia Okhota, Denys Titov, Svitlana Dotsiuk

“…To achieve this goal, the article discusses the theoretical aspects of energy independence, analyzes current practices of biofuel production, and provides recommendations for their further implementation. …”
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Towards a sustainable rare disease and orphan drug ecosystem in Saudi Arabia: policy insights from a multi-stakeholder workshop by Ghada Mohammed Abozaid, Ghada Mohammed Abozaid, Hussain Abdulrahman Al-Omar, Abdulaziz Alrabiah, Asma AlMuaither, Amy Jayne McKnight

“…Through a series of presentations, educational sessions, and plenary discussions, participants examined the current landscape of RDs in SA, identified barriers to accessing ODs, and recommended strategies and initiatives to improve the accessibility, innovation, and sustainability of ODs.ResultsThe workshop highlighted key challenges recognized by a diverse group of 59 participants, including the absence of a national strategy, absent of local RDs and ODs definitions in the Saudi context, limited awareness and understanding of RDs among healthcare professionals, delayed diagnoses, scarcity of treatment and diagnosis centers for RDs, insufficient screening and prevention programs, regulatory hurdles in approving and importing ODs, and financial constraints. …”
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